Bipolar Disorder

Childhood Abuse Linked to Compromised White Matter Integrity in Bipolar Disorder

Childhood Abuse Linked to Compromised White Matter Integrity in Bipolar Disorder

These findings are in line with previous research, which suggested that abuse and neglect in childhood have different effects on the brain.

Medication Adherence Predictors in Patients With Severe Psychiatric Disorders

Medication Adherence Predictors in Patients With Severe Psychiatric Disorders

As antipsychotic medications are vital to the effective management of severe psychiatric disorders, investigators sought to examine reasons for medication nonadherence in patients with schizophrenia, bipolar disorders, and other psychotic disorders.

Schizophrenia, Major Depressive Disorder, Bipolar Disorder Linked With Abnormal Functional Connectivity

Schizophrenia, Major Depressive Disorder, Bipolar Disorder Linked With Abnormal Functional Connectivity

Local functional connectivity may serve as neuroimaging marker to investigate the human brain connectome.

Personality Disorders Related to Adverse Outcomes in Bipolar Disorder

Personality Disorders Related to Adverse Outcomes in Bipolar Disorder

These data may lead to a more nuanced understanding of bipolar disorder and to a better definition of the effectiveness of interventions directed at treating both personality disorders and bipolar disorder.

Consensus Statement: Managing Bipolar Disorder During and After Pregnancy

Consensus Statement: Managing Bipolar Disorder During and After Pregnancy

Investigators summarize data regarding the management of bipolar disorder during pregnancy and in the postpartum period.

Childhood-Onset Bipolar Disorder Associated With Impaired Family Functioning

Childhood-Onset Bipolar Disorder Associated With Impaired Family Functioning

Further investigation into the family-based mechanisms of childhood-onset bipolar disorder may assist in the development of future targeted, effective therapies.

Omega-3 supplementation improves pediatric executive functioning

Omega-3 supplementation improves pediatric executive functioning

Omega-3 supplementation in children with mood disorders is associated with decreased impairment in executive functioning.

ECG may distinguish major depressive disorder from bipolar depression

ECG may distinguish major depressive disorder from bipolar depression

Heart rate variability and specific inflammatory biomarkers can differentiate major depressive disorder from depression in bipolar disorder.

Residual anxiety after venlafaxine treatment associated with depressive relapse

Residual anxiety after venlafaxine treatment associated with depressive relapse

Venlafaxine was superior to lithium in reducing symptoms of both bipolar II, depression, and anxiety.

FDA approves schizophrenia digital ingestion sensor

FDA approves schizophrenia digital ingestion sensor

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The US Food and Drug Administration has approved Abilify MyCite, which contains an ingestible sensor that records whether or not the medication was taken.

Asenapine decreases recurrence of manic, depressive episodes in bipolar disorder

Asenapine decreases recurrence of manic, depressive episodes in bipolar disorder

Asenapine shown to decrease the time to recurrence of manic and depressive episodes among patients with bipolar I disorder.

Psychosis not associated with worse outcomes in bipolar disorder

Psychosis not associated with worse outcomes in bipolar disorder

Psychosis was not associated with worse clinical or functional outcomes in patients with bipolar disorder.

Long-term response to mood stabilizers in patients with bipolar disorder

Long-term response to mood stabilizers in patients with bipolar disorder

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Mixed and psychotic features and comorbid anxiety disorder were also associated with poor treatment response.

Benefits of lithium vs quetiapine in patients with early manic bipolar episodes

Benefits of lithium vs quetiapine in patients with early manic bipolar episodes

Individuals with a first manic episode with psychotic features were randomly assigned to receive lithium or quetiapine monotherapy during the randomized controlled trial.

Women with bipolar disorder have high rate of sexual distress

Women with bipolar disorder have high rate of sexual distress

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Overall, 54% of women with bipolar disorder reported sexual distress and 39% were not satisfied with their sexual life.

Thyroid disease associated with higher incidence of manic relapse in bipolar disorder

Thyroid disease associated with higher incidence of manic relapse in bipolar disorder

Thyroid disease may be a risk factor for manic relapse in patients with bipolar disorder.

Risperidone treatment may delay relapse episodes in bipolar disorder

Risperidone treatment may delay relapse episodes in bipolar disorder

Researchers found that mood relapse episodes were delayed with risperidone long-acting injection.

Earlier depression diagnosis leads to longer delay in accurate bipolar disorder diagnosis

Earlier depression diagnosis leads to longer delay in accurate bipolar disorder diagnosis

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An earlier diagnosis of depression is associated with having a longer delay in conversion to bipolar disorder.

Bipolar depression: Early vs late response to treatment with lurasidone

Bipolar depression: Early vs late response to treatment with lurasidone

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The response to lurasidone between baseline and 2 weeks indicates later treatment success in bipolar depression.

Cognitive-behavioral therapy effective for bipolar disorder symptoms

Cognitive-behavioral therapy effective for bipolar disorder symptoms

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Cognitive-behavioral therapy effectively lowered the relapse rate and lessened depressive symptoms.

Case Study: Hyperglycemia, concern for diabetic ketoacidosis, and type 1 diabetes

Case Study: Hyperglycemia, concern for diabetic ketoacidosis, and type 1 diabetes

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A 36-year-old man with type 1 diabetes presents to the emergency room with hyperglycemia and possible diabetic ketoacidosis after not taking his insulin for 3 days.

Obesity may increase cognitive impairment in patients with risk of bipolar disorder

Obesity may increase cognitive impairment in patients with risk of bipolar disorder

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Patients with high risk for bipolar disorder are more likely to exhibit decreased cognitive performance as a function of increasing overweight status.

Lithium therapy may lead to silent thyroiditis in bipolar disorder

Lithium therapy may lead to silent thyroiditis in bipolar disorder

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Clinicians should monitor thyroid function when managing patients receiving lithium for bipolar disorder.

Cognitive remediation may improve executive function in bipolar disorder

Cognitive remediation may improve executive function in bipolar disorder

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Cognitive remediation may aid neurocognitive performance, including attention, working memory, and problem solving in bipolar disorder.

Psychiatric comorbid conditions may impact quality of life in bipolar disorder

Psychiatric comorbid conditions may impact quality of life in bipolar disorder

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Patients with greater clinical symptom severity had lower quality of life and higher functional impairment.

Mobile apps for bipolar disorder may not address consumer needs

Mobile apps for bipolar disorder may not address consumer needs

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Reviews containing "wishlists" indicate that consumer needs are not adequately addressed by the apps that are currently available.

Monotherapy and combined therapy for bipolar II disorder have similar responses

Monotherapy and combined therapy for bipolar II disorder have similar responses

The findings show no significant difference among sertraline monotherapy, lithium monotherapy, or a combination of the 2 medications.

Lithium not linked to increased cancer risk in patients with bipolar disorder

Lithium not linked to increased cancer risk in patients with bipolar disorder

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No difference was observed in risk of overall cancer in patients with bipolar disorder who use lithium, compared with the general population.

Atypical antipsychotic therapy with mood stabilizers effective after bipolar episode

Atypical antipsychotic therapy with mood stabilizers effective after bipolar episode

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Atypical antipsychotic adjunctive therapy and mood stabilizers may be a more effective treatment than mood stabilizer monotherapy.

Managing bipolar disorder: pharmacologic options for treatment

Managing bipolar disorder: pharmacologic options for treatment

Lithium has been the mainstay of treatment for decades, but several other classes of medication have recently been used with varying degrees of success.

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