Cardiovascular Information Center Archive

Aspirin discontinuation increases risk of cardiovascular events

Patients who discontinued aspirin use experience a higher risk of cardiovascular events.

New criteria developed for valvular heart disease testing

The report addresses the appropriate use of multiple imaging modalities available for clinicians in the evaluation of valvular heart disease, discussing the spectrum of patients.

Hormone replacement therapy for menopause not associated with increased mortality risk

The researchers found no long-term increase in either all-cause or cause-specific mortality among women who received hormone therapy for up to 5.6 years or 7.2 years, depending on the type of therapy.

Metabolically healthy obese individuals have increased risk of CVD events

Compared with normal-weight individuals, metabolically healthy obese individuals have an increased risk of coronary heart disease, cerebrovascular disease, and heart failure

Vitamin D supplements reduce depressive symptoms, cardiac events in moderate to severe depression

In patients with depressive symptoms, vitamin D deficiency with no additional supplements had the highest depressive score at 6 months and shortest cardiac event-free survival.

Managing hypertension in diabetes: a position statement from the ADA

The statement includes advances in care since the ADA's last position statement was published in 2003.

Natriuretic peptide-guided therapy does not improve outcomes in high-risk heart failure patients

NT-proBNP-guided treatment strategy did not improve outcomes compared with a usual care strategy in high-risk patients with heart failure.

Anti-inflammatory drug may reduce risk of cardiovascular events, lung cancer

The findings offer the first strong clinical evidence that inflammation-targeted therapy may reduce the risk of cardiovascular disease.

Sepsis, pneumonia lead to increased risk of cardiovascular disease in men

Men who are admitted to the hospital with a serious infection may have an increased risk of cardiovascular disease in the years immediately following the infection.

Managing high blood pressure in children: a clinical practice guideline

The AAP has released an updated clinical practice guideline for the diagnosis and management of high blood pressure in children.

Comparing anticoagulants to prevent venous thromboembolism after hip and knee arthroplasty

Fondaparinux and rivaroxaban were associated with increased risk of major bleeding in patients who underwent total hip or knee arthroplasty.

Increased mortality for percutaneous coronary intervention at safety-net hospitals

Risk-adjusted in-hospital mortality is significantly increased at safety-net hospitals for patients undergoing percutaneous coronary intervention.

Stroke incidence has decreased over time in men

The incidence of all strokes decreased over time in men, but not women, due to a decrease in ischemic stroke.

Marijuana use increases risk of hypertension-related mortality

Researchers found higher estimated cardiovascular risks associated with marijuana use than cigarette smoking.

Human embryo editing repairs genetic mutation that causes hypertrophic cardiomyopathy

The gene-editing tool called CRISPR-Cas9 could have the potential to treat and prevent other genetic diseases.

CVD prevention: New USPSTF guidelines for lifestyle counseling

The USPSTF updated their 2012 recommendations on behavior lifestyle counseling for preventing cardiovascular disease.

Ending statin therapy after initial stroke increases risk of recurrence

Stopping statin therapy 3 to 6 months after an initial ischemic stroke may increase risk of a recurrent stroke.

New data show aspirin safe for heart failure patients

Data from a clinical trial show that patients taking daily aspirin were not at heightened risk of being hospitalized for heart failure.

Moderate weight gain in early to middle adulthood linked to increased risk of chronic diseases

Adulthood weight gain is associated with an increased risk of major chronic diseases and mortality.

Higher childhood intelligence linked to lower mortality risk

Researchers sought to examine the link between intelligence scores during childhood and leading causes of death during the life course.

CPAP not effective in reducing cardiovascular events, mortality

The use of PAP, compared with no treatment or sham, was not associated with reduced risks of cardiovascular outcomes or death for patients with sleep apnea.

Idarucizumab reverses anticoagulant effect of dabigatran in emergency situations

Researchers found that idarucizumab is effective for dabigatran reversal among patients with uncontrolled bleeding and who are undergoing urgent surgery.

Opioid use increases risk of cardiac events in older COPD patients

Users of opioid-only agents had significantly increased rates of emergency room visits and hospitalizations for ischemic heart disease and IHD-related mortality.

Heart failure hospitalization rate declining in the United States

There were 526.86 hospital admissions for every 100,000 people in 2002, compared with 364.66 per 100,000 in 2013.

Managing patients with chronic heart failure

Clinicians will encounter more patients at risk for CHF as the population ages and cardiovascular risk factors become more prevalent.

Antiplatelet drug use may lead to bleeding risk in elderly

The researchers found that during 13,509 patient-years of follow-up, 3166 patients had 405 first bleeding events.

Many patients taking NOACs for atrial fibrillation may not be receiving correct dose

Researchers found that 16% of patients received doses inconsistent with US Food and Drug Administration labeling.

Restarting anticoagulation may be cost-effective in some VTE cases

The therapy may be cost-effective for patients with a predicted 1-year VTE risk of 17.5% or more.

Reducing blood pressure below recommended targets significantly reduces CVD, mortality risk

Blood pressure levels below the recommended targets lower risk of CVD and all-cause mortality.

Regular chocolate consumption may lower atrial fibrillation risk

Compared with individuals reporting chocolate intake less than once per month, the rate of AF was lower for people consuming chocolate regularly.

Statins vs usual care for primary cardiovascular prevention in older adults

The ALLHAT-LLT trial showed that statin therapy for primary cardiovascular prevention may not benefit adults older than 65 years of age.

Vitamin D not effective for preventing cardiovascular disease

CVD occurred in 11.8% of participants in the vitamin D group and 11.5% in the placebo group.

Screening for preeclampsia throughout pregnancy recommended by USPSTF

The USPSTF recommends that pregnant women receive screening for preeclampsia with blood pressure measurements throughout pregnancy.

Apixaban linked to lower risk of gastrointestinal bleeding

Apixaban is associated with a lower risk of gastrointestinal bleeding than rivaroxaban or dabigatran.

Statin eligibility differs between ACC/AHA vs USPSTF guidelines

Nine million fewer adults would be taking statins if clinicians followed the USPSTF guidelines.

Undiagnosed chest pain may increase long-term cardiovascular risk

Most patients in primary care with undiagnosed chest pain do not undergo diagnostic testing.

Moderate alcohol consumption linked to lower risk of some types of cardiovascular disease

The researchers found heterogeneity in the association between recorded alcohol consumption and the initial presentation of 12 cardiovascular diseases.

Knee osteoarthritis linked to increased risk of hypertension

Researchers observed a higher incidence of hypertension in patients with knee osteoarthritis compared with patients without osteoarthritis.

Valvular heart disease: 2017 updated guideline from the AHA/ACC

The updated guideline includes recent advances in diagnostic imaging and improvements in catheter-based and surgical interventions for patients with valvular heart disease.

Statins may reduce pulmonary artery pressure in COPD patients

A daily dose of atorvastatin could reduce pulmonary artery pressure among patients with COPD.

Physical activity important for adults with CVD

In older adults, the consequences of functional impairment include increased morbidity and mortality, and reduced ability to perform activities of daily living.

ICU may be overused for some patients with heart or lung disease

Researchers also observed no difference in 30-day mortality rates between patients in the ICU and those who received regular inpatient care in another hospital unit.

Dabigatran linked to fewer bleeding complications in patients with atrial fibrillation

Anticoagulation with dabigatran was associated with fewer bleeding complications compared with warfarin among patients undergoing ablation for atrial fibrillation.

Coronary reperfusion improved with longer time between antiplatelet therapy and PCI

A longer period between P2Y12 inhibitor administration and primary percutaneous coronary intervention improves coronary reperfusion.

Same-day discharge may be safe for patients after percutaneous coronary intervention

Same-day discharge after percutaneous coronary intervention for non-ST-segment elevation acute coronary syndromes was not predictive of 30-day readmission, death, or bleeding.

Hospitalization, mortality rates higher for heart failure patients in winter

Researchers find that hospitalizations and deaths among heart failure patients are highest during winter months.

Nearly half of all cardiometabolic deaths linked to poor diet

Suboptimal intake of 10 specific dietary factors is associated with a substantial proportion of deaths due to heart disease, stroke, or type 2 diabetes.

NSAID use for respiratory infection increases myocardial infarction risk

NSAID use during ARI was associated with a 3.4-fold increased risk of AMI compared with 2.7-fold increased risk without NSAID use.

Electronic cigarette use linked to higher CVD risk

Electronic cigarettes cause an imbalance of cardiac autonomic tone and increased oxidative stress, which may increase cardiovascular risk.

High-potency statins increase hospitalization for community-acquired pneumonia

Higher-potency statins increased hospitalization for community-acquired pneumonia compared with lower-potency statins.

Meal timing and frequency in CVD prevention: an AHA scientific statement

The AHA found that irregular eating patterns are less ideal for maintaining body weight and cardiometabolic health.

Diabetes without insulin may not increase thromboembolic risk in atrial fibrillation

Diabetes without insulin did not appear to increase thromboembolic risk in patients with atrial fibrillation treated with anticoagulation.

Efficacy of renin angiotensin system inhibitors for coronary artery disease

RASIs reduced cardiovascular events and death only when compared with placebo but not when compared with active controls.

Safety alert issued for LIFEPAK 1000 defibrillator

The device has shut down due to an intermittent connection between the battery and electrical contacts.

Increasing number of US adults with masked hypertension

An estimated 12.3% of Americans over the age of 21 have masked hypertension.

Caffeine may reduce age-related inflammation linked to cardiovascular disease

Researchers observed a connection between advancing age, systemic inflammation, cardiovascular disease, and caffeine.

Hypertension treatment in older adults: a new clinical practice guideline

The ACP and the AAFP has released a joint recommendation for the pharmacologic treatment of hypertension in adults aged 60 years and older.

"Weekend warrior" activity reduces all-cause mortality risk

Individuals who perform their physical activity in 1 or 2 sessions during the week can still reduce their risk of mortality.

Statin prescription rates lower among younger adults with severe dyslipidemia

Prescription rates for statins were dependent on age among patients with severe dyslipidemia.

Women using statins may have a lower risk of uterine fibroids

Researchers examined the association between statin use and the risk of uterine fibroids and fibroid-related symptoms.

Shared decision making boosts patients' knowledge of acute coronary syndrome risk

The use of a decision aid in patients at risk of acute coronary syndrome increased patient knowledge about their risk.

Statins may reduce risk of Alzheimer's disease

Depending on race, sex, and ethnicity, the right statin type may lower the risk of Alzheimer disease.

Regular alcohol consumption may increase risk of atrial fibrillation

Drinking small amounts of alcohol may increase the risk of atrial fibrillation.

Testosterone treatment may increase risk of venous thromboembolism

Researchers sought to determine the risk of venous thromboembolism associated with use of testosterone treatment.

Elevated blood pressure trends have shifted worldwide

The prevalence of elevated blood pressure rates shifted from high-income to low- and middle-income countries.

Dabigatran with statins increases hemorrhage risk in patients with atrial fibrillation

Patients who also took either lovastatin or simvastatin had a 40% higher risk of major hemorrhage than those who took other statins.

Managing peripheral artery disease: an updated guideline

The AHA/ACC guideline updates the 2005 recommendations on PAD management.

Warfarin may be linked to reduced thromboembolism in nonvalvular atrial fibrillation

The reduction in thromboembolism was attenuated after accounting for competing death events.

Statin and PCSK9 inhibitor combination more effective at lowering cholesterol

PCSK9 inhibition produces incremental benefits on coronary disease progression in patients treated with statins.

USPSTF releases final statin recommendations for CVD prevention

The task force finalizes recommendations for statin therapy among adults between 40 and 75 years of age.

Ambulatory diuretic therapy lowers costs in decompensated heart failure

Ambulatory high-dose intravenous diuretic therapy could be cost saving compared with hospitalization for intravenous loop diuretic therapy.

Caffeine does not induce arrhythmias in patients with heart disease

Caffeine consumption in patients with systolic heart failure does not induce arrhythmias both at rest and during physical exercise.

Pulmonary embolism common in patients hospitalized for syncope

One in 6 patients hospitalized for a first episode of syncope experiences a pulmonary embolism.

Depression may worsen outcomes in patients with chronic stable angina

Depression can occur in approximately 1 in 5 patients who have chronic stable angina.

New clinical practice guidelines for red blood cell transfusion

The AABB evaluated studies that examined hemoglobin thresholds for red blood cell transfusion and red blood cell storage duration.

NSAID use linked to increased risk of heart failure hospitalization

Some individual NSAIDs may be linked to increased risk of hospital admission for heart failure.

Vitamin D may not improve glucose measures in patients at risk for diabetes

Researchers observed significant improvement in LDL cholesterol in those at risk for diabetes.

Statin-based therapy less effective in advanced chronic kidney disease

Statin-based therapy had a smaller effect in reducing major vascular events in patients with advanced chronic kidney disease.

Alternative non-statin therapies effectively lower LDL cholesterol

Researchers found that dietary changes, other medications, and surgery can also lower cardiovascular risk.

European and American guidelines lead to different statin recommendations

Researchers observed a lower frequency of statin recommendation with ESC guidelines compared with the AHA/ACC guidelines.

Folic acid-fortified foods linked to lower risk of congenital heart defects

Foods fortified with folic acid are associated with a decrease in infants being born with congenital heart defects.

CPAP does not prevent cardiovascular events in obstructive sleep apnea

Patients with obstructive sleep apnea did not have reduced cardiovascular events after CPAP in addition to usual care.

Oily fish consumption may lower diabetic retinopathy risk in type 2 diabetes

A target intake of at least 500 mg/d is recommended to combat sight-threatening diabetic retinopathy.

AHA advisory: Sedentary behavior may increase cardiovascular morbidity and mortality

The American Heart Association has released a science advisory regarding the cardiovascular risks associated with sedentary behavior.

Lipid screening in children, adolescents: USPSTF recommendation statement

Current evidence is insufficient to weigh the balance of benefits and harms of screening.

Blood pressure lower than recommended level is beneficial in type 2 diabetes

Patients with type 2 diabetes with systolic blood pressure lower than 140 mm Hg have a lower risk of cardiovascular events.

Common medications can cause or worsen heart failure, cautions AHA

The American Heart Association has published a scientific statement that outlines which medications cause or exacerbate heart failure.

Vagal nerve stimulation does not reduce mortality in heart failure patients

At 16 months, 30.3% of patients either died or experienced worsening heart failure.

Patients with atrial fibrillation and stroke risk treated with aspirin over oral anticoagulants

Specific patient characteristics predicted the type of therapy more likely to be prescribed.

Postpartum readmission rates increase

Readmission was more common among publically insured, black patients presenting with comorbidities including hypertension and diabetes.

Whole grain consumption reduces chronic disease, all-cause mortality

Reductions in disease risk were observed for an intake as high as 7.5 servings of whole grains per day.

Coronary artery bypass linked to new-onset diabetes

Coronary artery bypass surgery may lead to metabolic changes, causing new-onset diabetes.

Smartphone app helps circumvent unnecessary testing for chest pain in ED patients

The HEART pathway app provides doctors in the ED with a digital application an already proven method of assessment.

Non-vitamin K antagonist oral anticoagulants may be safe, effective

Non-vitamin K antagonist oral anticoagulants perform similarly to warfarin for patients with atrial fibrillation.

Rates of CVD mortality declining in US

Researchers found that mortality rates dropped less than 1% between 2011 and 2014.

Alanine aminotransferase serum levels linked to cardiovascular event risk

Incident events were most common in those within the lowest tertile of basline ALT serum.

Renal function can predict preeclampsia in pregnant women with hypertension

Baseline renal function tests may predict the risk of preeclampsia and preterm birth for pregnant women with hypertension.

Intensive blood pressure reduction offers no added benefit in stroke outcomes

For patients with intracerebral hemorrhage, intensive blood pressure reduction has similar outcomes compared with standard treatment.

FDA warns that misuse of antidiarrheal loperamide can cause severe cardiac events

The FDA warns that the antidiarrheal loperamide can lead to serious cardiac events when taken in high doses.

ART may not reduce HIV-associated arterial inflammation

Antiretroviral therapy in HIV-positive patients did not decrease the progression of arterial inflammation.

Sign Up for Free e-newsletters