Cardiovascular Information Center Archive

Empagliflozin Impact on Life Expectancy Examined in T2DM Patients With CVD

For this analysis, the authors used follow-up data from all 7020 patients included in the EMPA-REG OUTCOME trial to estimate the effect of empagliflozin on all-cause mortality vs placebo over the duration of a patient's lifetime.

Wall Thickness Measured by MRI More Consistently Linked to CVD

Common carotid artery wall thickness measured using magnetic resonance imaging is more consistently associated with incident cardiovascular disease outcomes than intima-media thickness measured by ultrasound.

Updated Hypertension Guideline Directs Treatment to Those With High CVD Risk

Implementing ACC/AHA guideline would direct antihypertensive meds to adults at high CVD risk.

Morbidity, Mortality Up for Youth With CHD Presenting to ED

Children with congenital heart disease presenting to ED at increased risk for morbidity, mortality.

Lixisenatide Cuts Kidney Damage in Type 2 Diabetes and Coronary Syndrome

Lixisenatide reduces progression of urinary albumin-creatinine ratio in patients with macroalbuminuria.

Family History Linked to Early-Onset A-Fib in Minorities

Probands of African or Hispanic/Latino descent with early-onset atrial fibrillation are more likely than European Americans to have a first-degree relative with AF.

Diabetes Common in Patients With Ischemic, Hemorrhagic Stroke

Approximately 28% of stroke patients have diabetes, and the presence of diabetes can increase the risk for poor stroke outcome.

Southern Dietary Pattern Mediates Racial Difference in Hypertension

For both men and women, Southern dietary pattern is largest mediating factor for difference in hypertension.

Switching IV to Oral Antibiotics Noninferior for Some Endocarditis Events

For certain patients with endocarditis on the left side of the heart under stable condition, switching from intravenous (IV) antibiotics to orally administered antibiotics is noninferior to staying on IV treatment.

Risk of Venous Thromboembolism Recurrence High

At 6 months, rates for provoked, unprovoked, cancer-related VTE are 6.8, 6.92, 9.06 per 100 person-years.

Guidelines Updated for Adult Congenital Heart Disease

New classification system intended to capture complexity of anatomy and physiology of ACHD.

Policies Should Encourage Healthy Food Consumption

Aim should be to prevent CVD with environment where healthy foods are accessible, desirable.

Lorcaserin Facilitates Weight Loss in Overweight, Obese

Increased weight loss vs placebo with no rise in rate of extended major cardiovascular events.

Enlarged Kidneys in Neonates With Congenital Heart Disease

Kidneys of neonates with left heart obstruction consistently found to be larger than normal.

Risk Factors for Atherosclerotic Cardiovascular Disease in the South Asian Population

South Asians exhibit the highest rates of ASCVD among all ethnic groups, and the highest prevalence is in younger age groups; up to 25% of myocardial infarctions in India occur in individuals younger than 40 years of age.

New Risk Factors Identified for Varicose Vein Disease

Mendelian randomization analysis provides evidence that increased height causally tied to varicose veins.

Including Hypertensive Disorders of Pregnancy in CVD Risk Score Does Not Improve CVD Risk Prediction

Adding history of hypertensive disorders of pregnancy to the current cardiovascular disease (CVD) risk score does not improve CVD prediction in low-risk women.

No Clear Benefit for Rivaroxaban After Hospital Discharge

Incidence of major bleeding low with rivaroxaban, but clot risk not lower.

Intensive Blood Pressure Therapy Lowers Cardiovascular Risk in Diabetes

Intensive blood pressure therapy is associated with a significantly lower risk for serious cardiovascular events in the adults with diabetes.

ASPREE Trial: Aspirin Associated With Higher Mortality, Hemorrhage Risk in Older Adults

The use of aspirin in healthy elderly patients as a preventative strategy was associated with no prolongation of long-term disability-free survival compared with placebo.

Prurigo Nodularis More Likely in African-Americans

PN linked to chronic kidney disease, hepatitis C, congestive heart failure, HIV, psychiatric comorbidities.

AHA: Resistant Hypertension Diagnosis, Treatment Guidelines Updated

Ruling out prescription non-compliance, white coat syndrome, and interfering medications necessary.

Single, Fixed-Dose Combo Pills Improve Hypertension Outcomes

Findings show improved outcomes may be due to better medication adherence.

AHA: Update on Diagnosis, Treatment for Chagas Cardiomyopathy

Prevalence has increased in US; statement aims to increase recognition, improve care.

Increased Dairy Consumption Linked to Reduced CVD, Mortality Risk in Low-, Middle-Income Countries

The consumption of whole-fat dairy products may reduce cardiovascular disease and mortality risk, contrary to current dietary guidelines that advise limited consumption of fat-free or low-fat dairy products.

Reducing HF Hospitalization Risk: Antidiabetic Drug Classes Compared

The authors searched for randomized placebo-controlled trials (December 1, 2008 to November 24, 2017) involving 3 pharmacologic classes of antidiabetic medications to compare the effects of these agents on the risk of hospitalization for HF in T2DM patients.

Labor Induction Linked to Hypertensive Complication Prevention in Women With Chronic Hypertension

For expectant mothers with chronic hypertension, labor induction after 38 weeks of gestation may prevent hypertensive complications without increasing the risk of cesarean delivery.

New Guidelines Target Pharmacological Hypertension Management to High-Risk Patients

A guideline-based approach directing pharmacological treatment to adults more likely to have CVD events may maximize absolute risk reduction of treatment.

Excess Cardiac Risk Varies With Age of Onset of T1D

Excess risk differed by up to 5 times across different diagnosis age groups.

Assessing the Evidence of Aspirin for Primary Prevention in Diabetes

The substantial burden of cardiovascular disease in patients with diabetes has led to the exploration of various cardiovascular disease prevention strategies, including the use of aspirin.

CHEST Releases Guideline for Antithrombotic Therapy in Atrial Fibrillation

Patients with atrial fibrillation who have ≥1 non-sex CHA2DS2VASc stroke risk factor should receive oral anticoagulation as antithrombotic therapy.

Laryngeal Tube Insertion Beats Endotracheal Intubation in OHCA

And, 30-day functional outcomes similar with supraglottic airway device or tracheal intubation.

High LDL in Young, Healthy Adults Leaves Them Vulnerable to CVD

Findings may have implications for future cholesterol treatment paradigms.

Lower Long-Term Survival for In-Hospital Cardiac Arrests in Blacks

Black survivors of in-hospital cardiac arrest have lower survival at 1, 3, 5 years vs whites.

AHA/ACC: Updated Management Guidelines for Adult Congenital Heart Disease

The American College of Cardiology and American Heart Association developed updated guidelines on the evaluation, management, and monitoring of adults with congenital heart disease.

Triple Combo Blood Pressure Pill Can Improve BP Control

Proportion achieving target BP increased with use of triple combo pill vs usual care at 6 months.

Perspectives on USPSTF AF Screening Recommendation

Physicians weigh in on the need to develop a screening strategy.

Healthy Lifestyle With Diabetes Cuts Cardiovascular Risk

Benefit seen for adoption of healthy lifestyle even after T2DM diagnosis made.

AHA: A Diverse Diet May Not Promote a Healthy Weight

American Heart Association science advisory recommends healthy eating patterns instead.

No Impact on Carotid Artery Intima-Media Thickness Following Cessation of Menopausal Hormone Therapy

A follow-up study from KEEPS found that cessation of menopausal hormone therapy did not change the expected trajectory of carotid artery intima-media thickness over a 3-year period.

Review Addresses Nutritional Hype for Popular Foods

Legumes, coffee, tea tied to cardiovascular benefits; added sugars, energy drinks linked to harmful effects.

American Heart Association Urges Screen Time Limits for Youth

Increasing screen trends may have negative cardiometabolic impact; panel calls for more research.

USPSTF: Insufficient Evidence to Screen for Atrial Fibrillation

US Preventive Services Task Force says benefit unclear in asymptomatic, older patients.

'Good' Cholesterol May Not Be So in Postmenopausal Women

High total HDL cholesterol in postmenopausal women may mask heart disease risk.

AHA Introduces Heart Failure Certification Program

Program for heart failure management and implementation of clinical practice guidelines.

Infective Endocarditis More Common with Valve Issues

Antibiotic prophylaxis should be reconsidered with bicuspid aortic valve, mitral valve prolapse.

Independent Relationship Between CV Mortality, Oxidative DNA Damage in Type 2 Diabetes

This represents the prospective study confirming an independent relationship between cardiovascular mortality and oxidative DNA damage in type 2 diabetes.

2002 to 2014 Saw Hike in AMI Rate in Pregnancy, Puerperium

Rate of acute myocardial infarction one per 12,400 for those hospitalized during pregnancy, puerperium.

Use of 2017 ACC/AHA Guidelines Would Increase HTN Prevalence

Adoption of the guidelines would label more than half of 45- to 75-year-olds as having hypertension.

Portable Sleep Monitoring Accurate in Heart Failure Patients

Respiratory polygraphy can accurately diagnose sleep apnea in patients hospitalized with heart failure.

Increased Maternal Mortality Risk Associated With Recurrent Preeclampsia

Recurrent hypertensive disease of pregnancy is associated with increased risk for early all-cause and some cause-specific mortality.

NP, PA Treatment Comparable for Patients With CVD or Diabetes

Effectiveness of care and healthcare resource use for diabetes or cardiovascular disease were comparable among patients receiving care from an NP vs those managed by a PA.

Cardiac Pathology in SUDEP Compared With Sudden Arrhythmic or Traumatic Deaths

Causes of death in patients with epilepsy were assessed to determine the presence of cardiac pathology.

Preeclampsia With Severe Features Increases Risk for Cardiac Abnormalities

Women with preeclampsia with severe features had increased right ventricular systolic pressure and decreased global right ventricular longitudinal systolic strain.

More Youths With Hypertension Using 2017 AAP Guidelines

Weighted net estimated increase of 795,000 US youths being reclassified as having hypertension.

Acute Coronary Syndrome Risk Elevated in Siblings of Patients With RA

Siblings of patients with rheumatoid arthritis appear to have an increased risk for acute coronary syndrome, which suggests there is a shared susceptibility between the 2 conditions.

Wildfire Smoke Causes Health Risks

Agency offers steps to minimize exposure, particularly for those with chronic conditions.

Weight Loss Linked to Reversal of Atrial Fibrillation Progression

Increased weight loss with risk factor management associated with greater atrial fibrillation freedom.

Empagliflozin Reduces Risk for Nephropathy Regardless of Blood Pressure, LDL Cholesterol, HbA1c

Investigators examined renal outcomes when controlling cardiovascular risk factors, such as blood pressure, LDL-C, and HbA1c.

Discharge Tools, Follow-Up Calls Reduce Readmission for Congestive Heart Failure

A literature review revealed that the use of care navigators in conjunction with follow-up telephone calls from nursing staff improved transition of care and readmission rates in patients with congestive heart failure.

Clotting Time in Transfemoral PCI Linked to Bleeding Risk

More major bleeding seen at maximal activated clotting time greater than 290 seconds.

Home Blood Pressure Monitoring Systems Quality Assessment

An observational study was conducted in order to determine the accuracy and quality of readings provided by home blood pressure monitoring systems.

Handheld Device Can ID Cardiac Dysfunction in Cancer Survivors

Vivio can accurately detect cardiac dysfunction in anthracycline-exposed childhood cancer survivors

Risk of CV Events Down With Mediterranean Diet Plus Olive Oil, Nuts

Lower incidence of major cardiovascular events with Mediterranean diet supplemented with oil, nuts.

Sex Hormone Levels May Affect Postmenopausal Heart Disease Risk

Researchers assessed the effect of testosterone, estradiol, dehydroepiandrosterone, and sex hormone-binding globulin levels on coronary heart disease, heart failure, and cardiovascular disease in postmenopausal women.

NSAID Use May Increase CVD Risk in Osteoarthritis

Nonsteroidal anti-inflammatory drug use mediated a substantial amount of cardiovascular disease risk in osteoarthritis.

Higher Blood Pressure at Mid-Life Increases Dementia Risk

Findings for those with systolic BP 130 mm Hg at age 50 years

Peri-Op RBC Transfusions Linked to Postoperative VTE

Perioperative red blood cell transfusion linked to increased adjusted odds of VTE, DVT, PE

Exposure to Maternal HTN May Up Risk of ASD, ADHD in Child

Hypertensive disorders of pregnancy linked to risk of poorer neurodevelopmental outcomes in offspring

African American Adults Less Likely to Be Treated With Statins

Racial differences persist in statin use among adults, specifically African American adults, who are less likely to be treated with any statin or guideline-recommended statin intensity compared with white adults.

USPSTF Does Not Recommend ECG Screening in Low-Risk CVD

The United States Preventive Services Task Force does not recommend screening with resting or exercise electrocardiography in asymptomatic individuals at low risk for cardiovascular disease events.

Mortality Still High After Surgery for Congenital Heart Defects

Long-term mortality elevated even for mild defects; overall survival improved over time

Alcohol Consumption Inversely Linked to Nonfatal Coronary Heart Disease

Alcohol consumption may be inversely related to nonfatal CHD risk but positively correlated with risks for other stroke subtypes.

Male Thyroid Cancer Survivors Face Higher CVD Risk

Age at diagnosis, sex, BMI, and thyroid-stimulating hormone suppression therapy affect CVD risk

ACC Outlines Best Practices for Ionizing Radiation Use in Cardiovascular Imaging

The American College of Cardiology, along with several other cardiology societies, have updated guidelines on best practices for improving safety when using ionizing radiation during cardiovascular imaging.

Increase in Treating Candidates With 2017 Hypertension Guidelines

Increase in proportion of adults recommended for treatment; estimated decrease in CVD events, deaths.

Severe Atopic Eczema Tied to Higher CV Disease Risk

Risk of cardiovascular outcomes was greatest for those with the most active atopic eczema.

Atherosclerotic CVD Mortality Higher in South Asians in the US

Most of the increased risk can be attributed to increased prevalence of known risk factors.

Incident Gout Risk, Serum Urate, and Comorbidities: What Are the Links?

Ethnicity and hypertension have an association with incident gout that is not fully explained by differences in serum urate.

PAH Risk, Mortality Increased by Disturbances in Male Sex Hormones

Men with higher estradiol and estradiol/testosterone levels had an increased risk for pulmonary arterial hypertension.

Hand Grip Strength Associated With All-Cause Mortality, Other Adverse Outcomes

Grip strength is strongly and inversely associated with all-cause mortality and incidence of and mortality from cardiovascular disease, respiratory disease, COPD, all cancer, and subtypes of cancer, with associations being modestly stronger in the younger age groups.

Ischemic Heart Disease, CHF Mortality Vary Across VA Systems

Risk-standardized mortality rates vary considerably across Veterans Affairs Medical Centers

Acute Kidney Injury in Hospital Ups Risk of Later Heart Failure

Findings based on one-year follow-up after a hospitalization complicated by acute kidney injury

Electrical Device Helps Reduce Daily Salt Intake, Improve Blood Pressure

Using a simple self-monitoring device may help reduce salt intake and systolic blood pressure.

Disruption of Circadian Rhythm Negatively Impacts Mental Health

Reduction in relative amplitude tied to higher risk of lifetime major depressive disorder, bipolar disorder

Stroke, TIA Risk Remain High After Atrial Fibrillation Resolved

Patients with resolved atrial fibrillation have an increased risk for stroke or transient ischemic attack.

Case Study: Cardiovascular Complications of Chronic Obstructive Pulmonary Disease

A 55-year-old man with chronic obstructive pulmonary disease reports having some mild chest pain.

Hypertension Increase in Children Based on 2017 AAP Guidelines

Increase in estimated population prevalence of elevated blood pressure from 11.8 to 14.2%.

Smartphone App May Boost Medication Adherence in Hypertension

But use of the app not linked to a change in systolic blood pressure in poorly controlled hypertension

Study Finds Safe Alcohol Consumption Guidelines May Not Be Strict Enough

Among current drinkers without previous diagnosis of cardiovascular disease, the threshold for lowest risk of all-cause mortality is about 100 g of alcohol consumed per week.

Women Less Likely to Fill Post-MI Statin Prescription

Fifty-six percent of men, 47% of women filled high-intensity statin after myocardial infarction

Eating Pecans May Cut Risk of Cardiovascular Disease, Diabetes

Benefits seen in markers of cardiometabolic disease, including insulin sensitivity

Coffee Consumption Cuts Coronary Artery Calcification

There is an inverse association between coffee consumption and coronary artery calcium, especially among never smokers.

Aortic valve replacement linked to increased mortality in elderly

Aside from age, other high mortality factors included left ventricular dysfunction, atrial fibrillation, COPD, and diabetes.

Antidepressants, depression may increase atrial fibrillation risks

According to research presented at the 2018 American Heart Association's Epidemiology and Prevention/Lifestyle and Cardiometabolic Health Scientific Sessions in New Orleans.

FDA: World's smallest mechanical heart valve approved for newborns with heart defects

The world's smallest mechanical heart valve was approved by the FDA for newborns and young infants with heart defects.

High total cholesterol linked to lower risk of cognitive decline in elderly

Cognitive decline risk is lowered in individuals aged 85 and older with high cholesterol.

Cholesterol drug may lower risk for death and cardiovascular events

Alirocumab significantly decreased severe cardiovascular risks in patients with acute coronary syndrome.

Oral fluoroquinolone use is linked to increased aortic aneurysm, dissection risks

Aortic aneurysm risks are significantly elevated in patients taking fluoroquinolone.

Undiagnosed CV events low for elderly patients in emergency department

Medicare patients with ED visits pertaining to imminent ruptured abdominal aortic aneurysms, stroke, acute myocardial infarctions, or other cardiovascular relating events are very likely to be diagnosed prior to hospital discharge.

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