Cardiovascular Information Center Archive

Empagliflozin Reduces Risk for Nephropathy Regardless of Blood Pressure, LDL Cholesterol, HbA1c

Investigators examined renal outcomes when controlling cardiovascular risk factors, such as blood pressure, LDL-C, and HbA1c.

Discharge Tools, Follow-Up Calls Reduce Readmission for Congestive Heart Failure

A literature review revealed that the use of care navigators in conjunction with follow-up telephone calls from nursing staff improved transition of care and readmission rates in patients with congestive heart failure.

Clotting Time in Transfemoral PCI Linked to Bleeding Risk

More major bleeding seen at maximal activated clotting time greater than 290 seconds.

Home Blood Pressure Monitoring Systems Quality Assessment

An observational study was conducted in order to determine the accuracy and quality of readings provided by home blood pressure monitoring systems.

Handheld Device Can ID Cardiac Dysfunction in Cancer Survivors

Vivio can accurately detect cardiac dysfunction in anthracycline-exposed childhood cancer survivors

Risk of CV Events Down With Mediterranean Diet Plus Olive Oil, Nuts

Lower incidence of major cardiovascular events with Mediterranean diet supplemented with oil, nuts.

Sex Hormone Levels May Affect Postmenopausal Heart Disease Risk

Researchers assessed the effect of testosterone, estradiol, dehydroepiandrosterone, and sex hormone-binding globulin levels on coronary heart disease, heart failure, and cardiovascular disease in postmenopausal women.

NSAID Use May Increase CVD Risk in Osteoarthritis

Nonsteroidal anti-inflammatory drug use mediated a substantial amount of cardiovascular disease risk in osteoarthritis.

Higher Blood Pressure at Mid-Life Increases Dementia Risk

Findings for those with systolic BP 130 mm Hg at age 50 years

Peri-Op RBC Transfusions Linked to Postoperative VTE

Perioperative red blood cell transfusion linked to increased adjusted odds of VTE, DVT, PE

Exposure to Maternal HTN May Up Risk of ASD, ADHD in Child

Hypertensive disorders of pregnancy linked to risk of poorer neurodevelopmental outcomes in offspring

African American Adults Less Likely to Be Treated With Statins

Racial differences persist in statin use among adults, specifically African American adults, who are less likely to be treated with any statin or guideline-recommended statin intensity compared with white adults.

USPSTF Does Not Recommend ECG Screening in Low-Risk CVD

The United States Preventive Services Task Force does not recommend screening with resting or exercise electrocardiography in asymptomatic individuals at low risk for cardiovascular disease events.

Mortality Still High After Surgery for Congenital Heart Defects

Long-term mortality elevated even for mild defects; overall survival improved over time

Alcohol Consumption Inversely Linked to Nonfatal Coronary Heart Disease

Alcohol consumption may be inversely related to nonfatal CHD risk but positively correlated with risks for other stroke subtypes.

Male Thyroid Cancer Survivors Face Higher CVD Risk

Age at diagnosis, sex, BMI, and thyroid-stimulating hormone suppression therapy affect CVD risk

ACC Outlines Best Practices for Ionizing Radiation Use in Cardiovascular Imaging

The American College of Cardiology, along with several other cardiology societies, have updated guidelines on best practices for improving safety when using ionizing radiation during cardiovascular imaging.

Increase in Treating Candidates With 2017 Hypertension Guidelines

Increase in proportion of adults recommended for treatment; estimated decrease in CVD events, deaths.

Severe Atopic Eczema Tied to Higher CV Disease Risk

Risk of cardiovascular outcomes was greatest for those with the most active atopic eczema.

Atherosclerotic CVD Mortality Higher in South Asians in the US

Most of the increased risk can be attributed to increased prevalence of known risk factors.

Incident Gout Risk, Serum Urate, and Comorbidities: What Are the Links?

Ethnicity and hypertension have an association with incident gout that is not fully explained by differences in serum urate.

PAH Risk, Mortality Increased by Disturbances in Male Sex Hormones

Men with higher estradiol and estradiol/testosterone levels had an increased risk for pulmonary arterial hypertension.

Hand Grip Strength Associated With All-Cause Mortality, Other Adverse Outcomes

Grip strength is strongly and inversely associated with all-cause mortality and incidence of and mortality from cardiovascular disease, respiratory disease, COPD, all cancer, and subtypes of cancer, with associations being modestly stronger in the younger age groups.

Ischemic Heart Disease, CHF Mortality Vary Across VA Systems

Risk-standardized mortality rates vary considerably across Veterans Affairs Medical Centers

Acute Kidney Injury in Hospital Ups Risk of Later Heart Failure

Findings based on one-year follow-up after a hospitalization complicated by acute kidney injury

Electrical Device Helps Reduce Daily Salt Intake, Improve Blood Pressure

Using a simple self-monitoring device may help reduce salt intake and systolic blood pressure.

Disruption of Circadian Rhythm Negatively Impacts Mental Health

Reduction in relative amplitude tied to higher risk of lifetime major depressive disorder, bipolar disorder

Stroke, TIA Risk Remain High After Atrial Fibrillation Resolved

Patients with resolved atrial fibrillation have an increased risk for stroke or transient ischemic attack.

Case Study: Cardiovascular Complications of Chronic Obstructive Pulmonary Disease

A 55-year-old man with chronic obstructive pulmonary disease reports having some mild chest pain.

Hypertension Increase in Children Based on 2017 AAP Guidelines

Increase in estimated population prevalence of elevated blood pressure from 11.8 to 14.2%.

Smartphone App May Boost Medication Adherence in Hypertension

But use of the app not linked to a change in systolic blood pressure in poorly controlled hypertension

Study Finds Safe Alcohol Consumption Guidelines May Not Be Strict Enough

Among current drinkers without previous diagnosis of cardiovascular disease, the threshold for lowest risk of all-cause mortality is about 100 g of alcohol consumed per week.

Women Less Likely to Fill Post-MI Statin Prescription

Fifty-six percent of men, 47% of women filled high-intensity statin after myocardial infarction

Eating Pecans May Cut Risk of Cardiovascular Disease, Diabetes

Benefits seen in markers of cardiometabolic disease, including insulin sensitivity

Coffee Consumption Cuts Coronary Artery Calcification

There is an inverse association between coffee consumption and coronary artery calcium, especially among never smokers.

Aortic valve replacement linked to increased mortality in elderly

Aside from age, other high mortality factors included left ventricular dysfunction, atrial fibrillation, COPD, and diabetes.

Antidepressants, depression may increase atrial fibrillation risks

According to research presented at the 2018 American Heart Association's Epidemiology and Prevention/Lifestyle and Cardiometabolic Health Scientific Sessions in New Orleans.

FDA: World's smallest mechanical heart valve approved for newborns with heart defects

The world's smallest mechanical heart valve was approved by the FDA for newborns and young infants with heart defects.

High total cholesterol linked to lower risk of cognitive decline in elderly

Cognitive decline risk is lowered in individuals aged 85 and older with high cholesterol.

Cholesterol drug may lower risk for death and cardiovascular events

Alirocumab significantly decreased severe cardiovascular risks in patients with acute coronary syndrome.

Oral fluoroquinolone use is linked to increased aortic aneurysm, dissection risks

Aortic aneurysm risks are significantly elevated in patients taking fluoroquinolone.

Undiagnosed CV events low for elderly patients in emergency department

Medicare patients with ED visits pertaining to imminent ruptured abdominal aortic aneurysms, stroke, acute myocardial infarctions, or other cardiovascular relating events are very likely to be diagnosed prior to hospital discharge.

Varicose veins associated with increased risk of deep venous thrombosis

There is a significant association between varicose veins and an increased risk for deep venous thrombosis and possible associations with pulmonary embolism and peripheral artery disease, though results are still unclear.

Noninvasive coronary testing may prevent need for future invasive tests

Low-risk acute coronary syndrome patients may require fewer referrals for invasive coronary angiography if they had initial noninvasive testing such as stress echocardiography or cardiovascular magnetic resonance.

Obesity associated with elevated CVD mortality, morbidity

Obesity is affiliated with elevated morbidity, cardiovascular disease related mortality, and shorter longevity compared with individuals with a normal body mass index.

ACC: Changes in temperature linked to STEMI

Large changes in temperature are associated with increased risk of ST-segment elevation myocardial infarction.

Cancer history affects mortality risk independent of CV risk

Cancer history has an important impact on mortality independent of cardiovascular risk factors.

Cardiac surgery during flu season linked to ARDS

Undergoing cardiac surgery during the influenza season is associated with increased likelihood of development of acute respiratory distress syndrome.

Patent foramen ovale associated with stroke risk after noncardiac surgery

Patients diagnosed with PFO prior to noncardiac surgery have an elevated ischemic stroke risk.

Standards of Medical Care in Diabetes modified for cardiovascular disease

The ADA's updates include a modified patient-focused care algorithm as well as improved risk management for CVD.

Migraine associated with increased risk of cardiovascular events

Migraines are linked to cardiovascular events, including myocardial infarction, VTE, and stroke.

Gestational diabetes increases T2D, hypertension, heart disease risk

Women with gestational diabetes have a greater risk of developing T2D and cardiovascular events than women who were not previously diagnosed with the disease.

Breastfeeding may lower hypertension risk in postmenopausal women

Breastfeeding duration and frequency may help reduce hypertension risks.

NFL players do not have significantly increased mortality risk

Among NFL football players who began their careers between 1982 and 1992, career participation in the NFL, compared with limited NFL exposure obtained primarily as an NFL replacement player during a league-wide strike, was not associated with a statistically significant difference in long-term all-cause mortality.

Heart failure, hearing loss linked in older patients

Patients with heart failure might have a greater risk for cardiovascular comorbidities and hearing loss.

Depressive symptoms may increase mortality risk in patients undergoing aortic valve replacement

In patients undergoing TAVR or SAVR, approximately 1 in 3 had depressive symptoms at baseline and a higher risk of short-term and midterm mortality.

Acute ischemic stroke: new guidelines open treatment window to 24 hours

At the 2018 International Stroke Conference in Los Angeles, the AHA/ASA released updated guidelines for the early management of ischemic strokes, which account for 87% of all strokes.

Evidence of marijuana's effect on cardiovascular events still scarce

Future studies may help to assess the relation between chronic marijuana use and cardiovascular risks.

Early menarche, menopause linked to increased CVD risk

Several reproductive variables were independently linked to increased CVD risks.

USPSTF: Evidence insufficient for unconventional CVD risk factors

According to the USPSTF, evidence is lacking to investigate nontraditional risk factors for CVD risk evaluation.

New long-acting bronchodilator use linked to CV risk in COPD patients

Use of long-acting bronchodilators is linked to cardiovascular risks in patients with COPD.

Mechanically expanded TAVR may benefit high-risk aortic stenosis patients

MEV aortic valve replacement is noninferior to SEV aortic valve replacement in high-risk patients with aortic stenosis.

Addition of new class of antihypertensive drug effective for lowering BP

Addition of a new class of antihypertensive drugs to existing treatment greatly decreases SBP in previously medicated patients with HT.

Positive attitude linked to lower mortality risk after cardiovascular event

Positive emotions and low levels of depression after a cardiovascular disease (CVD) event are associated with low risk for mortality during a 15-year period.

USPSTF screening recommendation for use of ECG in atrial fibrillation, CVD

The USPSTF has found that the current evidence is inadequate to assess the benefits and harms of screening with ECG for atrial fibrillation and cardiovascular disease in older adults.

Ginkgo biloba extract aids cognition in stroke patients

Ginkgo biloba extract, along with aspiring, may help cognition in acute ischemic stroke patients.

Compression ultrasounds assist GPs in diagnosing DVTs

Accuracy was 95.8% for DVT diagnosis for general practitioners using compression ultrasonography.

AAFP does not endorse new hypertension guideline

The AAFP continues to use the 2014 JNC8 guideline instead of the 2017 AHA/ACC update.

Blood pressure decreases more than a decade before death

Blood pressure decreases more than a decade before death in patients older than 60 years.

VTE risk linked to increased television watching

Increased frequency of television viewing may be linked to an increased risk for venous thromboembolism.

DOACs vs warfarin for stroke prevention in atrial fibrillation

Many direct acting oral anticoagulants may be more beneficial than warfarin.

Low-dose aspirin ineffective for venous leg ulcers

Low-dose aspirin does not decrease healing time for patients with venous leg ulcers.

Endovascular strategy more effective than open repair for ruptured abdominal aortic aneurysms

Treating patients with ruptured abdominal aortic aneurysms with endovascular strategy over open repair may increase survival and decrease cost.

FDA warns that febuxostat may increase risk of heart-related mortality

Preliminary clinical trial results show more heart-related deaths occur in patients taking febuxostat compared to allopurinol.

AHA, ACC release new clinical guideline for managing hypertension in adults

The AHA and ACC have released a new guideline that categorizes more US adults as hypertensive.

Statins associated with increased risk of diabetes in high-risk individuals

Statins are associated with an increased risk for developing type 2 diabetes, especially for high-risk individuals.

Dual antithrombotic therapy with dabigatran reduces bleeding risk after PCI in atrial fibrillation

Dual therapy with dabigatran and a P2Y12 inhibitor resulted in a lower risk of bleeding events compared with triple therapy with warfarin, a P2Y12 inhibitor, and aspirin.

Appropriate use criteria developed for aortic stenosis

Appropriate use criteria for the treatment of patients with severe aortic stenosis includes the use of surgical aortic valve replacement and transcatheter aortic valve replacement.

PPI use associated with risk of stroke, myocardial infarction

Use of PPIs was associated with increased risks of first -time ischemic stroke and MI, particularly among long -term users and at high doses.

Direct oral anticoagulants vs warfarin for bleeding risk in VTE

Compared with warfarin, treatment with DOACs was not associated with an increased risk of major bleeding or all-cause mortality within the first 90 days.

Statin use decreases the risk of community-acquired Staphylococcus aureus

Compared with nonusers, current statin users experienced markedly decreased risk of CA-SAB.

Mid-adulthood hypertension linked to dementia risk in women

Among women, but not men, mid-adulthood hypertension correlated with a 65% increased dementia risk.

Aspirin discontinuation increases risk of cardiovascular events

Patients who discontinued aspirin use experience a higher risk of cardiovascular events.

New criteria developed for valvular heart disease testing

The report addresses the appropriate use of multiple imaging modalities available for clinicians in the evaluation of valvular heart disease, discussing the spectrum of patients.

Hormone replacement therapy for menopause not associated with increased mortality risk

The researchers found no long-term increase in either all-cause or cause-specific mortality among women who received hormone therapy for up to 5.6 years or 7.2 years, depending on the type of therapy.

Metabolically healthy obese individuals have increased risk of CVD events

Compared with normal-weight individuals, metabolically healthy obese individuals have an increased risk of coronary heart disease, cerebrovascular disease, and heart failure

Vitamin D supplements reduce depressive symptoms, cardiac events in moderate to severe depression

In patients with depressive symptoms, vitamin D deficiency with no additional supplements had the highest depressive score at 6 months and shortest cardiac event-free survival.

Managing hypertension in diabetes: a position statement from the ADA

The statement includes advances in care since the ADA's last position statement was published in 2003.

Natriuretic peptide-guided therapy does not improve outcomes in high-risk heart failure patients

NT-proBNP-guided treatment strategy did not improve outcomes compared with a usual care strategy in high-risk patients with heart failure.

Anti-inflammatory drug may reduce risk of cardiovascular events, lung cancer

The findings offer the first strong clinical evidence that inflammation-targeted therapy may reduce the risk of cardiovascular disease.

Sepsis, pneumonia lead to increased risk of cardiovascular disease in men

Men who are admitted to the hospital with a serious infection may have an increased risk of cardiovascular disease in the years immediately following the infection.

Managing high blood pressure in children: a clinical practice guideline

The AAP has released an updated clinical practice guideline for the diagnosis and management of high blood pressure in children.

Comparing anticoagulants to prevent venous thromboembolism after hip and knee arthroplasty

Fondaparinux and rivaroxaban were associated with increased risk of major bleeding in patients who underwent total hip or knee arthroplasty.

Increased mortality for percutaneous coronary intervention at safety-net hospitals

Risk-adjusted in-hospital mortality is significantly increased at safety-net hospitals for patients undergoing percutaneous coronary intervention.

Stroke incidence has decreased over time in men

The incidence of all strokes decreased over time in men, but not women, due to a decrease in ischemic stroke.

Marijuana use increases risk of hypertension-related mortality

Researchers found higher estimated cardiovascular risks associated with marijuana use than cigarette smoking.

Human embryo editing repairs genetic mutation that causes hypertrophic cardiomyopathy

The gene-editing tool called CRISPR-Cas9 could have the potential to treat and prevent other genetic diseases.

CVD prevention: New USPSTF guidelines for lifestyle counseling

The USPSTF updated their 2012 recommendations on behavior lifestyle counseling for preventing cardiovascular disease.

Ending statin therapy after initial stroke increases risk of recurrence

Stopping statin therapy 3 to 6 months after an initial ischemic stroke may increase risk of a recurrent stroke.

New data show aspirin safe for heart failure patients

Data from a clinical trial show that patients taking daily aspirin were not at heightened risk of being hospitalized for heart failure.

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