Cardiovascular Disease

PPI use associated with risk of stroke, myocardial infarction

PPI use associated with risk of stroke, myocardial infarction

Use of PPIs was associated with increased risks of first -time ischemic stroke and MI, particularly among long -term users and at high doses.

Direct oral anticoagulants vs warfarin for bleeding risk in VTE

Direct oral anticoagulants vs warfarin for bleeding risk in VTE

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Compared with warfarin, treatment with DOACs was not associated with an increased risk of major bleeding or all-cause mortality within the first 90 days.

Statin use decreases the risk of community-acquired <i>Staphylococcus aureus</i>

Statin use decreases the risk of community-acquired Staphylococcus aureus

Compared with nonusers, current statin users experienced markedly decreased risk of CA-SAB.

Aspirin discontinuation increases risk of cardiovascular events

Aspirin discontinuation increases risk of cardiovascular events

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Patients who discontinued aspirin use experience a higher risk of cardiovascular events.

New criteria developed for valvular heart disease testing

New criteria developed for valvular heart disease testing

The report addresses the appropriate use of multiple imaging modalities available for clinicians in the evaluation of valvular heart disease, discussing the spectrum of patients.

Hormone replacement therapy for menopause not associated with increased mortality risk

Hormone replacement therapy for menopause not associated with increased mortality risk

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The researchers found no long-term increase in either all-cause or cause-specific mortality among women who received hormone therapy for up to 5.6 years or 7.2 years, depending on the type of therapy.

Metabolically healthy obese individuals have increased risk of CVD events

Metabolically healthy obese individuals have increased risk of CVD events

Compared with normal-weight individuals, metabolically healthy obese individuals have an increased risk of coronary heart disease, cerebrovascular disease, and heart failure

Managing hypertension in diabetes: a position statement from the ADA

Managing hypertension in diabetes: a position statement from the ADA

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The statement includes advances in care since the ADA's last position statement was published in 2003.

Natriuretic peptide-guided therapy does not improve outcomes in high-risk heart failure patients

Natriuretic peptide-guided therapy does not improve outcomes in high-risk heart failure patients

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NT-proBNP-guided treatment strategy did not improve outcomes compared with a usual care strategy in high-risk patients with heart failure.

Anti-inflammatory drug may reduce risk of cardiovascular events, lung cancer

Anti-inflammatory drug may reduce risk of cardiovascular events, lung cancer

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The findings offer the first strong clinical evidence that inflammation-targeted therapy may reduce the risk of cardiovascular disease.

Sepsis, pneumonia lead to increased risk of cardiovascular disease in men

Sepsis, pneumonia lead to increased risk of cardiovascular disease in men

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Men who are admitted to the hospital with a serious infection may have an increased risk of cardiovascular disease in the years immediately following the infection.

Managing high blood pressure in children: a clinical practice guideline

Managing high blood pressure in children: a clinical practice guideline

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The AAP has released an updated clinical practice guideline for the diagnosis and management of high blood pressure in children.

Comparing anticoagulants to prevent venous thromboembolism after hip and knee arthroplasty

Comparing anticoagulants to prevent venous thromboembolism after hip and knee arthroplasty

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Fondaparinux and rivaroxaban were associated with increased risk of major bleeding in patients who underwent total hip or knee arthroplasty.

Increased mortality for percutaneous coronary intervention at safety-net hospitals

Increased mortality for percutaneous coronary intervention at safety-net hospitals

Risk-adjusted in-hospital mortality is significantly increased at safety-net hospitals for patients undergoing percutaneous coronary intervention.

Stroke incidence has decreased over time in men

Stroke incidence has decreased over time in men

The incidence of all strokes decreased over time in men, but not women, due to a decrease in ischemic stroke.

Marijuana use increases risk of hypertension-related mortality

Marijuana use increases risk of hypertension-related mortality

Researchers found higher estimated cardiovascular risks associated with marijuana use than cigarette smoking.

Human embryo editing repairs genetic mutation that causes hypertrophic cardiomyopathy

Human embryo editing repairs genetic mutation that causes hypertrophic cardiomyopathy

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The gene-editing tool called CRISPR-Cas9 could have the potential to treat and prevent other genetic diseases.

CVD prevention: New USPSTF guidelines for lifestyle counseling

CVD prevention: New USPSTF guidelines for lifestyle counseling

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The USPSTF updated their 2012 recommendations on behavior lifestyle counseling for preventing cardiovascular disease.

Ending statin therapy after initial stroke increases risk of recurrence

Ending statin therapy after initial stroke increases risk of recurrence

Stopping statin therapy 3 to 6 months after an initial ischemic stroke may increase risk of a recurrent stroke.

A faster heart rate and numbness: Is the patient having a heart attack?

A faster heart rate and numbness: Is the patient having a heart attack?

A 30-year-old woman presents with an increased heart rate, shortness of breath, and tingling in her right arm.

New data show aspirin safe for heart failure patients

New data show aspirin safe for heart failure patients

Data from a clinical trial show that patients taking daily aspirin were not at heightened risk of being hospitalized for heart failure.

Moderate weight gain in early to middle adulthood linked to increased risk of chronic diseases

Moderate weight gain in early to middle adulthood linked to increased risk of chronic diseases

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Adulthood weight gain is associated with an increased risk of major chronic diseases and mortality.

Higher childhood intelligence linked to lower mortality risk

Higher childhood intelligence linked to lower mortality risk

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Researchers sought to examine the link between intelligence scores during childhood and leading causes of death during the life course.

CPAP not effective in reducing cardiovascular events, mortality

CPAP not effective in reducing cardiovascular events, mortality

The use of PAP, compared with no treatment or sham, was not associated with reduced risks of cardiovascular outcomes or death for patients with sleep apnea.

Idarucizumab reverses anticoagulant effect of dabigatran in emergency situations

Idarucizumab reverses anticoagulant effect of dabigatran in emergency situations

Researchers found that idarucizumab is effective for dabigatran reversal among patients with uncontrolled bleeding and who are undergoing urgent surgery.

Opioid use increases risk of cardiac events in older COPD patients

Opioid use increases risk of cardiac events in older COPD patients

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Users of opioid-only agents had significantly increased rates of emergency room visits and hospitalizations for ischemic heart disease and IHD-related mortality.

Managing systolic heart failure

Managing systolic heart failure

Primary care providers can help significantly reduce heart failure exacerbations and improve their patients' overall quality of life.

Heart failure hospitalization rate declining in the United States

Heart failure hospitalization rate declining in the United States

There were 526.86 hospital admissions for every 100,000 people in 2002, compared with 364.66 per 100,000 in 2013.

Managing patients with chronic heart failure

Managing patients with chronic heart failure

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Clinicians will encounter more patients at risk for CHF as the population ages and cardiovascular risk factors become more prevalent.

Antiplatelet drug use may lead to bleeding risk in elderly

Antiplatelet drug use may lead to bleeding risk in elderly

The researchers found that during 13,509 patient-years of follow-up, 3166 patients had 405 first bleeding events.

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