Cardiovascular Disease

Comparing anticoagulants to prevent venous thromboembolism after hip and knee arthroplasty

Comparing anticoagulants to prevent venous thromboembolism after hip and knee arthroplasty

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Fondaparinux and rivaroxaban were associated with increased risk of major bleeding in patients who underwent total hip or knee arthroplasty.

Increased mortality for percutaneous coronary intervention at safety-net hospitals

Increased mortality for percutaneous coronary intervention at safety-net hospitals

Risk-adjusted in-hospital mortality is significantly increased at safety-net hospitals for patients undergoing percutaneous coronary intervention.

Stroke incidence has decreased over time in men

Stroke incidence has decreased over time in men

The incidence of all strokes decreased over time in men, but not women, due to a decrease in ischemic stroke.

Marijuana use increases risk of hypertension-related mortality

Marijuana use increases risk of hypertension-related mortality

Researchers found higher estimated cardiovascular risks associated with marijuana use than cigarette smoking.

Human embryo editing repairs genetic mutation that causes hypertrophic cardiomyopathy

Human embryo editing repairs genetic mutation that causes hypertrophic cardiomyopathy

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The gene-editing tool called CRISPR-Cas9 could have the potential to treat and prevent other genetic diseases.

CVD prevention: New USPSTF guidelines for lifestyle counseling

CVD prevention: New USPSTF guidelines for lifestyle counseling

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The USPSTF updated their 2012 recommendations on behavior lifestyle counseling for preventing cardiovascular disease.

Ending statin therapy after initial stroke increases risk of recurrence

Ending statin therapy after initial stroke increases risk of recurrence

Stopping statin therapy 3 to 6 months after an initial ischemic stroke may increase risk of a recurrent stroke.

A faster heart rate and numbness: Is the patient having a heart attack?

A faster heart rate and numbness: Is the patient having a heart attack?

A 30-year-old woman presents with an increased heart rate, shortness of breath, and tingling in her right arm.

New data show aspirin safe for heart failure patients

New data show aspirin safe for heart failure patients

Data from a clinical trial show that patients taking daily aspirin were not at heightened risk of being hospitalized for heart failure.

Moderate weight gain in early to middle adulthood linked to increased risk of chronic diseases

Moderate weight gain in early to middle adulthood linked to increased risk of chronic diseases

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Adulthood weight gain is associated with an increased risk of major chronic diseases and mortality.

Higher childhood intelligence linked to lower mortality risk

Higher childhood intelligence linked to lower mortality risk

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Researchers sought to examine the link between intelligence scores during childhood and leading causes of death during the life course.

CPAP not effective in reducing cardiovascular events, mortality

CPAP not effective in reducing cardiovascular events, mortality

The use of PAP, compared with no treatment or sham, was not associated with reduced risks of cardiovascular outcomes or death for patients with sleep apnea.

Idarucizumab reverses anticoagulant effect of dabigatran in emergency situations

Idarucizumab reverses anticoagulant effect of dabigatran in emergency situations

Researchers found that idarucizumab is effective for dabigatran reversal among patients with uncontrolled bleeding and who are undergoing urgent surgery.

Opioid use increases risk of cardiac events in older COPD patients

Opioid use increases risk of cardiac events in older COPD patients

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Users of opioid-only agents had significantly increased rates of emergency room visits and hospitalizations for ischemic heart disease and IHD-related mortality.

Managing systolic heart failure

Managing systolic heart failure

Primary care providers can help significantly reduce heart failure exacerbations and improve their patients' overall quality of life.

Heart failure hospitalization rate declining in the United States

Heart failure hospitalization rate declining in the United States

There were 526.86 hospital admissions for every 100,000 people in 2002, compared with 364.66 per 100,000 in 2013.

Managing patients with chronic heart failure

Managing patients with chronic heart failure

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Clinicians will encounter more patients at risk for CHF as the population ages and cardiovascular risk factors become more prevalent.

Antiplatelet drug use may lead to bleeding risk in elderly

Antiplatelet drug use may lead to bleeding risk in elderly

The researchers found that during 13,509 patient-years of follow-up, 3166 patients had 405 first bleeding events.

Many patients taking NOACs for atrial fibrillation may not be receiving correct dose

Many patients taking NOACs for atrial fibrillation may not be receiving correct dose

Researchers found that 16% of patients received doses inconsistent with US Food and Drug Administration labeling.

Restarting anticoagulation may be cost-effective in some VTE cases

Restarting anticoagulation may be cost-effective in some VTE cases

The therapy may be cost-effective for patients with a predicted 1-year VTE risk of 17.5% or more.

Reducing blood pressure below recommended targets significantly reduces CVD, mortality risk

Reducing blood pressure below recommended targets significantly reduces CVD, mortality risk

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Blood pressure levels below the recommended targets lower risk of CVD and all-cause mortality.

Regular chocolate consumption may lower atrial fibrillation risk

Regular chocolate consumption may lower atrial fibrillation risk

Compared with individuals reporting chocolate intake less than once per month, the rate of AF was lower for people consuming chocolate regularly.

Statins vs usual care for primary cardiovascular prevention in older adults

Statins vs usual care for primary cardiovascular prevention in older adults

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The ALLHAT-LLT trial showed that statin therapy for primary cardiovascular prevention may not benefit adults older than 65 years of age.

Vitamin D not effective for preventing cardiovascular disease

Vitamin D not effective for preventing cardiovascular disease

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CVD occurred in 11.8% of participants in the vitamin D group and 11.5% in the placebo group.

Screening for preeclampsia throughout pregnancy recommended by USPSTF

Screening for preeclampsia throughout pregnancy recommended by USPSTF

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The USPSTF recommends that pregnant women receive screening for preeclampsia with blood pressure measurements throughout pregnancy.

Apixaban linked to lower risk of gastrointestinal bleeding

Apixaban linked to lower risk of gastrointestinal bleeding

Apixaban is associated with a lower risk of gastrointestinal bleeding than rivaroxaban or dabigatran.

Statin eligibility differs between ACC/AHA vs USPSTF guidelines

Statin eligibility differs between ACC/AHA vs USPSTF guidelines

Nine million fewer adults would be taking statins if clinicians followed the USPSTF guidelines.

Undiagnosed chest pain may increase long-term cardiovascular risk

Undiagnosed chest pain may increase long-term cardiovascular risk

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Most patients in primary care with undiagnosed chest pain do not undergo diagnostic testing.

Moderate alcohol consumption linked to lower risk of some types of cardiovascular disease

Moderate alcohol consumption linked to lower risk of some types of cardiovascular disease

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The researchers found heterogeneity in the association between recorded alcohol consumption and the initial presentation of 12 cardiovascular diseases.

Case Study: Chest pain radiating into the neck

Case Study: Chest pain radiating into the neck

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A 44-year-old man presents to his local urgent care clinic for chest pain radiating up into his neck that is gradually getting worse.

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