Cardiovascular Disease

DOACs vs warfarin for stroke prevention in atrial fibrillation

DOACs vs warfarin for stroke prevention in atrial fibrillation

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Many direct acting oral anticoagulants may be more beneficial than warfarin.

Low-dose aspirin ineffective for venous leg ulcers

Low-dose aspirin ineffective for venous leg ulcers

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Low-dose aspirin does not decrease healing time for patients with venous leg ulcers.

Endovascular strategy more effective than open repair for ruptured abdominal aortic aneurysms

Endovascular strategy more effective than open repair for ruptured abdominal aortic aneurysms

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Treating patients with ruptured abdominal aortic aneurysms with endovascular strategy over open repair may increase survival and decrease cost.

FDA warns that febuxostat may increase risk of heart-related mortality

FDA warns that febuxostat may increase risk of heart-related mortality

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Preliminary clinical trial results show more heart-related deaths occur in patients taking febuxostat compared to allopurinol.

AHA, ACC release new clinical guideline for managing hypertension in adults

AHA, ACC release new clinical guideline for managing hypertension in adults

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The AHA and ACC have released a new guideline that categorizes more US adults as hypertensive.

Statins associated with increased risk of diabetes in high-risk individuals

Statins associated with increased risk of diabetes in high-risk individuals

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Statins are associated with an increased risk for developing type 2 diabetes, especially for high-risk individuals.

Case Study: Cardiac conditions of rheumatoid arthritis

Case Study: Cardiac conditions of rheumatoid arthritis

A 69-year-old man with no prior medical history presents over the course of several months with new-onset nonspecific joint pain and swelling without evidence of erosions.

Dual antithrombotic therapy with dabigatran reduces bleeding risk after PCI in atrial fibrillation

Dual antithrombotic therapy with dabigatran reduces bleeding risk after PCI in atrial fibrillation

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Dual therapy with dabigatran and a P2Y12 inhibitor resulted in a lower risk of bleeding events compared with triple therapy with warfarin, a P2Y12 inhibitor, and aspirin.

Appropriate use criteria developed for aortic stenosis

Appropriate use criteria developed for aortic stenosis

Appropriate use criteria for the treatment of patients with severe aortic stenosis includes the use of surgical aortic valve replacement and transcatheter aortic valve replacement.

PPI use associated with risk of stroke, myocardial infarction

PPI use associated with risk of stroke, myocardial infarction

Use of PPIs was associated with increased risks of first -time ischemic stroke and MI, particularly among long -term users and at high doses.

Direct oral anticoagulants vs warfarin for bleeding risk in VTE

Direct oral anticoagulants vs warfarin for bleeding risk in VTE

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Compared with warfarin, treatment with DOACs was not associated with an increased risk of major bleeding or all-cause mortality within the first 90 days.

Statin use decreases the risk of community-acquired <i>Staphylococcus aureus</i>

Statin use decreases the risk of community-acquired Staphylococcus aureus

Compared with nonusers, current statin users experienced markedly decreased risk of CA-SAB.

Aspirin discontinuation increases risk of cardiovascular events

Aspirin discontinuation increases risk of cardiovascular events

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Patients who discontinued aspirin use experience a higher risk of cardiovascular events.

New criteria developed for valvular heart disease testing

New criteria developed for valvular heart disease testing

The report addresses the appropriate use of multiple imaging modalities available for clinicians in the evaluation of valvular heart disease, discussing the spectrum of patients.

Hormone replacement therapy for menopause not associated with increased mortality risk

Hormone replacement therapy for menopause not associated with increased mortality risk

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The researchers found no long-term increase in either all-cause or cause-specific mortality among women who received hormone therapy for up to 5.6 years or 7.2 years, depending on the type of therapy.

Metabolically healthy obese individuals have increased risk of CVD events

Metabolically healthy obese individuals have increased risk of CVD events

Compared with normal-weight individuals, metabolically healthy obese individuals have an increased risk of coronary heart disease, cerebrovascular disease, and heart failure

Managing hypertension in diabetes: a position statement from the ADA

Managing hypertension in diabetes: a position statement from the ADA

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The statement includes advances in care since the ADA's last position statement was published in 2003.

Natriuretic peptide-guided therapy does not improve outcomes in high-risk heart failure patients

Natriuretic peptide-guided therapy does not improve outcomes in high-risk heart failure patients

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NT-proBNP-guided treatment strategy did not improve outcomes compared with a usual care strategy in high-risk patients with heart failure.

Anti-inflammatory drug may reduce risk of cardiovascular events, lung cancer

Anti-inflammatory drug may reduce risk of cardiovascular events, lung cancer

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The findings offer the first strong clinical evidence that inflammation-targeted therapy may reduce the risk of cardiovascular disease.

Sepsis, pneumonia lead to increased risk of cardiovascular disease in men

Sepsis, pneumonia lead to increased risk of cardiovascular disease in men

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Men who are admitted to the hospital with a serious infection may have an increased risk of cardiovascular disease in the years immediately following the infection.

Managing high blood pressure in children: a clinical practice guideline

Managing high blood pressure in children: a clinical practice guideline

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The AAP has released an updated clinical practice guideline for the diagnosis and management of high blood pressure in children.

Comparing anticoagulants to prevent venous thromboembolism after hip and knee arthroplasty

Comparing anticoagulants to prevent venous thromboembolism after hip and knee arthroplasty

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Fondaparinux and rivaroxaban were associated with increased risk of major bleeding in patients who underwent total hip or knee arthroplasty.

Increased mortality for percutaneous coronary intervention at safety-net hospitals

Increased mortality for percutaneous coronary intervention at safety-net hospitals

Risk-adjusted in-hospital mortality is significantly increased at safety-net hospitals for patients undergoing percutaneous coronary intervention.

Stroke incidence has decreased over time in men

Stroke incidence has decreased over time in men

The incidence of all strokes decreased over time in men, but not women, due to a decrease in ischemic stroke.

Marijuana use increases risk of hypertension-related mortality

Marijuana use increases risk of hypertension-related mortality

Researchers found higher estimated cardiovascular risks associated with marijuana use than cigarette smoking.

Human embryo editing repairs genetic mutation that causes hypertrophic cardiomyopathy

Human embryo editing repairs genetic mutation that causes hypertrophic cardiomyopathy

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The gene-editing tool called CRISPR-Cas9 could have the potential to treat and prevent other genetic diseases.

CVD prevention: New USPSTF guidelines for lifestyle counseling

CVD prevention: New USPSTF guidelines for lifestyle counseling

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The USPSTF updated their 2012 recommendations on behavior lifestyle counseling for preventing cardiovascular disease.

Ending statin therapy after initial stroke increases risk of recurrence

Ending statin therapy after initial stroke increases risk of recurrence

Stopping statin therapy 3 to 6 months after an initial ischemic stroke may increase risk of a recurrent stroke.

A faster heart rate and numbness: Is the patient having a heart attack?

A faster heart rate and numbness: Is the patient having a heart attack?

A 30-year-old woman presents with an increased heart rate, shortness of breath, and tingling in her right arm.

New data show aspirin safe for heart failure patients

New data show aspirin safe for heart failure patients

Data from a clinical trial show that patients taking daily aspirin were not at heightened risk of being hospitalized for heart failure.

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