Constipation

Secretagogues Compared in Irritable Bowel Syndrome With Constipation

Secretagogues Compared in Irritable Bowel Syndrome With Constipation

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While several secretagogues have been recently approved by the Food and Drug Administration (FDA), a lack of head-to-head trials led researchers to conduct a systematic review to compare the effectiveness of these agents in patients with IBS-C.

Constipation: Diagnosis and treatment overview

Constipation: Diagnosis and treatment overview

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Strong evidence for efficacy has been established for stimulant and osmotic laxatives, new intestinal secretagogues, and peripherally restricted μ-opiate receptor antagonists, according to a review in JAMA.

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