Generic Name and Formulations:
Glatiramer acetate 20mg/mL, 40mg/mL; soln for SC inj; contains mannitol; preservative-free.
Indications for COPAXONE:
To reduce the frequency of relapses in patients with relapsing-remitting multiple sclerosis, including those who have experienced a first clinical episode and have MRI features consistent with multiple sclerosis.
Supervise 1st dose. Rotate inj sites (arms, abdomen, hips, thighs). ≥18yrs: 20mg SC once daily or 40mg SC three times weekly (at least 48hrs apart). The 20mg/mL and 40mg/mL injections are not interchangeable.
<18yrs: not recommended.
Not for IV inj. Pregnancy (Cat.B). Nursing mothers.
Inj site and post-inj reactions, vasodilatation, rash, dyspnea, chest pain, asthenia, infection, pain, nausea, arthralgia, anxiety, hypertonia; rare: lipoatrophy, skin necrosis, modified immune response.
Single-use prefilled syringes 20mg/mL—30; 40mg/mL—12