Asymptomatic red lesions

Asymptomatic red lesions

Two patients present with asymptomatic red lesions -- a 60-year-old man, whose lesion was present for five years before beginning to bleed, and a 27-year-old man whose lesion doubled in size during a two year period. Can you differentiate between the two?

Bimalar facial rashes

Bimalar facial rashes

A 54-year-old nurse and a 26-year old woman both present with bimalar facial rashes caused by two different things. Can you tell the difference?

Trunk rashes with central clearing

Trunk rashes with central clearing

Two patients present with oval-shaped plaques with central clearing on the trunk. Can you tell the difference?

Growing skin plaques with scale

Growing skin plaques with scale

Two patients present to the dermatology clinic with scaly pruritic lesions on the forearm. Can you differentiate between the two?

Diffuse erythematous papules

Diffuse erythematous papules

A 3-year-old boy and 45-year-old man present separately to the dermatology clinic with similar looking erythematous rashes. Can you differentiate between the two?

Linear pink plaques

Linear pink plaques

Two patients present to the dermatology clinic with pink rashes — one with a hyperpigmented rough patch on the nose, the other with pink papules in a linear pattern on the lateral thigh.

Yellow processes on the face

Yellow processes on the face

A patient presents with a yellow plaque on her left eyelid and a yellow papule on her left cheek. Are the two related?

Yellow papules near the nipple

Yellow papules near the nipple

A woman presents with papules on the areola that had been enlarging for several months. A man presents with protuberant papules with a red, yellow and whitish hue. Can you differentiate between the two?

Newly developed brown papules

Newly developed brown papules

Two patients present with newly developed brown papules. The first patient, a 45-year-old man, presented with a new mole that continues to grow and is associated with occasional pruritus and bleeding. The second patient, a 47-year-old man, presented with a 6-month history of a brown, growing "mole." Can you differentiate between the two?

Discoloration of the eyelid

Discoloration of the eyelid

Two patients present with discoloration of the eyelid. The first patient, a black woman aged 65, presents with velvety plaques and skin tags near hear right area that did not itch, burn or hurt. The second, an 8 year old boy with a family history of atopy, presented with eyelid dermatitis. Can you differentiate between the two?

Growths on the fingers

Growths on the fingers

Two patients present with growths on the fingers. The first patient, black woman aged 45 years, presents with papules on the outside of her pinkies that had been present since birth, had not grown and did not bother her. The second, is a man aged 40 years with a six-month history of a growth on the side of one middle finger. Can you differentiate between the two?

Vascular nodules and papules

Vascular nodules and papules

Two patients present with red lesions. A white infant aged 4 months presented with a three-month history of a red, verrucous nodule on his scalp, that grew from a small papule to a 3-cm nodule. A white man aged 50 years who had developed red papules on his legs, arms, chest and abdomen 20 years earlier, noticed that a group of the papules grew together to form a plaque. Can you differentiate between these two patients' lesions?

Pustular facial eruptions

Pustular facial eruptions

Two patients present with facial pustules, a 35-year-old man and an 18-year old woman. Can you differentiate between these two different dermatologic conditions?

Infant hand and foot blisters

Infant hand and foot blisters

Two patients present with blisters. One has bilateral blister formation on the dorsum of the hands, the other has blisters on the foot, face and diaper regions. Can you differentiate between the two?

Hair loss in an adult and a child

Hair loss in an adult and a child

Two patients present with hair loss. The first, a 55-year-old gay man presented with patchy-scalp hair loss. The scalp did not itch, burn or hurt, and was not scaly. The other patient, an 8-year-old boy with a several month history of hair loss and palpable lymph nodes. Can you differentiate between the two?

Painless, annular lesions

Painless, annular lesions

Two patients present with painless annular lesions. One presented to the dermatology clinic with a two-month history of a ringed rash on his abdomen, and the other patient had a three-week history of a slowly enlarging, pruritic rash on his left arm. Can you differentiate between the two?

Pediatric facial rashes

Pediatric facial rashes

Two patients present facial rashes. One presented to the dermatology clinic with an eight-month history of an asymptomatic progressive rash on his arms and legs, and the other patient had a history of multiple nonmelanoma skin cancers presented with asymptomatic scaly lesions on his hands, arms, and head. Can you differentiate between the two?

Infants with hypopigmented processes

Infants with hypopigmented processes

Two patients present with similar hyperpigmented spots on the skin — one with a series of macules on the cheek, and the other with lesions on his back.

Scaly papules in sun-exposed areas

Two patients present with scaly papules. One presented to the dermatology clinic with an eight-month history of an asymptomatic progressive rash on his arms and legs, and the other patient had a history of multiple nonmelanoma skin cancers with asymptomatic scaly lesions on his hands, arms and head.

Papules caused by insect bites

Papules caused by insect bites

Two patients present with insect bites — one after walking in brush while vacationing and another after doing yard work. Can you differentiate between the two?

Dystrophies of the nail

Two patients present with dystrophies of the nail—one with a several-year history of yellowed toenails and the other with grooved thumbnails.

Red lesions on the extremities

Two women present with similar red lesions on the extremities—one thought she had ringworm, and the other became severely ill after getting several vaccinations.

Cutaneous lesions

Cutaneous lesions

Two patients present with similar cutaneous growths—one a series of ulcerative lesions on the lower leg, and the other a painless forearm lesion.

Patches of hair loss

Patches of hair loss

Two boys with similar patches of hair loss—one developed six months ago, and the other had been present since birth.

Enlarging back and shoulder lesions

Enlarging back and shoulder lesions

Two patients with enlarging lesions—one in a man with no history of skin cancer, and the other in a man with significant actinic damage

Red rashes on the lower legs

Two patients present with leg rashes. One rash developed after a woman started taking cefazolin, and the other featured the deposition of hemosiderin.

Hypopigmented patches on the body

Two young girls with hypopigmented patches—one on the right buttock, the other on the knees, fingers, and ankles.

Purple eruptions

Purple eruptions

Two patients with purple lesions and no other abnormal skin findings.

Erythematous truncal plaques

Erythematous truncal plaques

Two patients with erythematous trunk plaques—the first developed eight months earlier, and the other 15 years ago.

Vesiculobullous eruptions

Two patients present with similar vesiculobullous eruptions. One was preceded by painful mouth sores, the other had no oral involvement.

Reminders of sun exposure

Sun exposure is the common link between these two conditions. Can you tell them apart?

Can you identify these similar scalp nodules?

Two women present with growing scalp nodules. One patient reported recent unintentional weight loss.

Coalescing purpuric plaques

Can you distinguish between two purpuric plaques on patients' legs?

A pair of generalized red rashes

Two men present with red rashes—one started on the back and spread to the upper arms, and the other was limited to the chest.

Facial plaques in aging men

Two aging men develop similar-appearing asymptomatic facial plaques.

Discrete areas of hair loss

A 40-year-old woman and a 3-year-old boy experience similar patterns of hair loss—one of sudden onset and the other present at birth.

Axillary papules and plaques

Differentiating two similar-appearing cases of axillary papules and plaques

Similar-appearing vesicles

Two women, the first bedridden with high fever and the second otherwise healthy, present with a vesicular rash.

Differentiating cutaneous dells

Two men present with cutaneous heel lesions. Similar growths appear on the patients' hands as well.

Itchless, pigmented macules

Itchless, pigmented macules

Can you distinguish between these two facial lesions with similar characteristics?

Perinasal papules

Two men with papules on the nose, cheeks, and forehead.

Two plaque-type eruptions

Two plaque-type eruptions

Painful lesions on a man's axilla and groin and a woman's breast. Can you guess the correct diagnosis?

Painful pedal erythema

Two elderly men present with painful red rashes on their feet and lower leg. One patient had a history of gout, the other essential thrombocytosis.

Painful pedal lesions

Painful pedal lesions

An 18-year-old student and a 72-year-old woman bear similar pedal lesions that interfere with walking.

A pair of solitary nodules

A pair of solitary nodules

One man had a nodule on his palm, and another had one on his leg. Both lesions were painless, but the diagnoses were very different.

Two erythematous leg rashes

Two erythematous leg rashes

Two women with considerable comorbidities present with lower leg trouble.

Papules and renal disease

Asymptomatic hyperkeratotic papules affect two women.

Nuchal plaques

Two cases of neck plaques—one that gets more pruritic at night and one that worsens after a visit to the barber.

Erosive lesions on the hand

Similar-appearing ulcerative hand lesions

Distinguishing dysplastic nevi

Two patients presented with similar multiple moles on the extremities and torso. Can you tell which case was mild and which was severe?

Pink papules on the fingers

Two patients with pink-purple hand papules—but only one shows interface dermatitis and lymphocytic infiltrate.

Two cases of gray hair

Two cases of gray hair—one localized and one widespread. Put together the clues and try to make the diagnosis.

Bluish-purple facial papules

Two patients with bluish-purple facial papules—one on the nose and the other on the lower lip

Cystic lesions on the hands

Two cases of lymphedema

White eruptions on the penis

Sorting out oral striations

Two ichthyosiform eruptions

Two reticulated eruptions

Two shiny, flat eruptions

Two vesicular eruptions

Two yellow-crusted eruptions

Hypopigmented head lesions

Brown-black eruptions

Armloads of pigmentation

A pair of acral nevi

Treatment-resistant alopecias

A pair of pigment disorders

Differentiating cystlike nodules

Eruptions of the hand

Blue bumps on the body

Tan-brown macules

Skin-fold eruptions

Linear white facial eruptions

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