Depressive Disorders

Retirement Associated With Increased Risk for Depressive Symptoms

Retirement Associated With Increased Risk for Depressive Symptoms

Employment status displayed a lagged effect on depression, with retirement preceding higher levels of depression 2 years after initial retirement status report.

Light Therapy Offers Nonpharmacologic Treatment for Perimenopausal Depression

Light Therapy Offers Nonpharmacologic Treatment for Perimenopausal Depression

Light treatments successfully corrected abnormal timing of melatonin circadian rhythms in perimenopausal women with depression and improved mood and sleep within 2 weeks.

Combinatorial Pharmacogenetics Useful in Treatment for Depression

Combinatorial Pharmacogenetics Useful in Treatment for Depression

These data support the clinical use of combinatorial pharmacogenetics for patients with major depressive disorder.

Antidepressants and Bleeding Risk: What's the Link?

Antidepressants and Bleeding Risk: What's the Link?

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Results showed an increased risk of bleeding with SRIs by 1.16-2.36 times with an even higher 3.17- to 10.9-fold risk with concomitant NSAIDs.

Efavirenz Does Not Increase Depression, Suicidal Ideation in HIV-Infected

Efavirenz Does Not Increase Depression, Suicidal Ideation in HIV-Infected

No increased risk of depression or suicidal ideation among persons living with HIV in Uganda.

Medications with depression as a possible adverse effect associated with increased depression risk

In this cross-sectional study, the use of medications with depression as an adverse effect was associated with a higher prevalence of depression while a similar association was not observed for medications without depression as a possible side effect.

Older Age Tied to Poorer Course of Major Depressive Disorder

Older Age Tied to Poorer Course of Major Depressive Disorder

Results were slightly attenuated but remained mostly significant with adjustment for prognostic factors

When Antidepressants Fail, Dose Increase May Be a Less Effective Response

When Antidepressants Fail, Dose Increase May Be a Less Effective Response

As this and previous research on dose increase strategies have produced inconsistent findings, the researchers recommended clinicians consider other responses to antidepressant treatment failure, at least for selective serotonin reuptake inhibitors.

Major Depression in Males May Lower Chances of Conception

Major Depression in Males May Lower Chances of Conception

Active major depression in women not associated with negative fertility outcomes.

Disruption of Circadian Rhythm Negatively Impacts Mental Health

Disruption of Circadian Rhythm Negatively Impacts Mental Health

Reduction in relative amplitude tied to higher risk of lifetime major depressive disorder, bipolar disorder

Resistance Exercise May Reduce Depressive Symptoms in Adults

Resistance Exercise May Reduce Depressive Symptoms in Adults

Meta-analysis shows reduction in depressive symptoms with RET, with considerable heterogeneity

Pediatric irritability, depressive moods linked to suicidality in adolescence

Pediatric irritability, depressive moods linked to suicidality in adolescence

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Children with chronic irritability, including depressive or anxious moods, may be at an increased risk for suicidality or suicidal thoughts as adolescents.

Antidepressant Types Linked to Different Adverse Outcomes in Adults with Depression

Antidepressant Types Linked to Different Adverse Outcomes in Adults with Depression

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Selective serotonin reuptake inhibitors and other antidepressants, such as tricyclic antidepressants, are associated with increased adverse outcomes in patients aged 20 to 64 years diagnosed with depression.

Depression awareness, knowledge improved with peer awareness program

Depression awareness, knowledge improved with peer awareness program

After program initiation in 10 high schools, students responded positively to the campaign by having greater awareness, better identification skills of depression, and reduced stigma.

<i>DSM-5</i> major depressive disorder diagnosis prevalence still high in US

DSM-5 major depressive disorder diagnosis prevalence still high in US

Investigators sought to determine the national prevalence of adults with a major depressive disorder diagnosis according to DSM-5 from 2012 to 2013.

Effective treatments for depression still not initiated in primary care

Effective treatments for depression still not initiated in primary care

The chances of starting treatment were doubled for patients under 44 years compared to patients older than 60.

Cognitive behavioral therapy may prevent relapse in major depressive disorder

Cognitive behavioral therapy may prevent relapse in major depressive disorder

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For major depressive disorder patients in remission, cognitive behavioral therapy is an effective intervention for relapse prevention at either short- or long-term follow-up.

New guidelines issued for adolescent depression in primary care

New guidelines issued for adolescent depression in primary care

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The American Academy of Pediatrics has updated clinical practice guidelines to assist primary care clinicians in the management of adolescent depression.

All antidepressants more effective than placebo for major depression

All antidepressants more effective than placebo for major depression

Some of the most effective antidepressants included agomelatine, amitriptyline, escitalopram, and mirtazapine.

Group cognitive behavior therapy, sertraline psychotherapy similar for depression treatment

Group cognitive behavior therapy, sertraline psychotherapy similar for depression treatment

Sertraline and group cognitive behavioral therapy have similar long-term antidepressant effects in the treatment of mild to moderate depression.

Women have twofold higher depression rate than men

Women have twofold higher depression rate than men

Depression less common in as family income increased and less common in non-Hispanic Asians.

PTSD symptoms reduced with prolonged exposure treatment

PTSD symptoms reduced with prolonged exposure treatment

Prolonged exposure therapy reduced PTSD symptom severity more than minimal-contact control.

Depressive symptoms may predict mortality in head, neck cancer

Depressive symptoms may predict mortality in head, neck cancer

Depressive symptoms at the time of treatment planning can predict overall 2 year mortality in patients with head and neck cancer.

Positive attitude linked to lower mortality risk after cardiovascular event

Positive attitude linked to lower mortality risk after cardiovascular event

Positive emotions and low levels of depression after a cardiovascular disease (CVD) event are associated with low risk for mortality during a 15-year period.

Analyzing differences in illness and outcomes for anxious depression

Analyzing differences in illness and outcomes for anxious depression

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Ranging definitions of anxiety associated with depression have caused variations in findings.

US surgical residents have high stress, burnout levels

US surgical residents have high stress, burnout levels

US Surgical residents have severe stress and high burnout levels during general training.

Patients with a mental health disorder more likely to refuse pharmacotherapy

Patients with a mental health disorder more likely to refuse pharmacotherapy

Differences in refusal rates for pharmacotherapy and psychotherapy were particularly evident for depressive disorders, panic disorder, and social anxiety disorder.

ADA releases guidelines for psychosocial care for diabetes patients

ADA releases guidelines for psychosocial care for diabetes patients

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The position statement provides recommendations for psychosocial assessment and care of individuals with diabetes.

Many adults with depression are not receiving treatment

Many adults with depression are not receiving treatment

Survey results revealed that only 28.7% of patients with depression receive any treatment.

Sertraline may prevent depressive disorders after traumatic brain injury

Sertraline may prevent depressive disorders after traumatic brain injury

The number needed to treat was 5.9 for sertraline vs placebo to prevent depression after a traumatic brain injury.

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