Dermatology News Archives

Methotrexate vs tumor necrosis factor inhibitors for pediatric psoriasis

Medication-related adverse events occur more frequently with methotrexate in children with moderate to severe psoriasis.

Many atopic dermatitis patients have inadequate disease control

Physicians rate a high proportion of patients with atopic dermatitis as having inadequate disease control.

Adolescent acne not linked to malignant melanoma in men

Body mass index is linked to malignant melanoma in men.

Oxybenzone in lotion linked to dermatological, environmental toxicity

Oxybenzone, found in sunscreens and other products, has harmful dermatological and environmental effects.

Methotrexate treatment improves symptoms of severe atopic dermatitis

Methotrexate treatment is associated with a significant improvement in symptoms of moderate to severe atopic dermatitis compared with cyclosporine treatment.

AJCC melanoma staging system is revised

American Joint Commtitee on Cancer melamona staging system revised.

Severe psoriasis linked to higher mortality risk

Patients with psoriasis whose disease affects >10% of their body surface area (BSA) are at an increased risk for death compared with the general population.

Dermatology guideline authors frequently fail to disclose sizable industry payments

Discrepancies were observed in disclosure forms of industry payments received by authors of dermatology clinical practice guidelines.

Sleep disturbance in psoriasis leads to psychological and physical predictors

Sleep complaints among individuals with psoriasis warrant greater clinical attention, as they have a greater chance for developing obstructive sleep apnea.

Psoriasis patients have an increased risk of alcohol-related mortality

Patients with psoriasis have a greater risk of mortality due to alcohol-related causes, including alcoholic liver disease, fibrosis and cirrhosis of the liver, and mental and behavioral disorders.

Secukinumab well-tolerated in patients with scalp psoriasis

This study shows that more than 50% of patients can expect a 90% or greater improvement in scalp psoriasis within 12 weeks.

Oral isotretinoin better than topical treatment for warts

Oral isotretinoin showed the best response in cases of facial warts

Smoking may be a risk factor for psoriasis

Researchers observed a positive correlation between the amount and duration of smoking and the occurrence of psoriasis.

Noninvasive test effective for monitoring hepatic fibrosis in psoriasis patients taking methotrexate

NASH FibroSure is useful to monitor for risk of worsening fibrosis during MTX therapy.

Biosimilar ABP 501 and adalimumab safe and effective for plaque psoriasis

Biosimilar ABP 501 has similar clinical efficacy and safety to adalimumab for the treatment of plaque psoriasis.

Candida antigen safe and effective treatment for common warts

The treatment is a promising, effective, and safe immunotherapeutic modality for common warts.

Dalazatide effective for skin lesions in plaque psoriasis

Dalazatide treatment reduced the plasma levels of multiple inflammation markers and reduced the expression of T cell activation markers on peripheral blood memory T cells.

Screening guidelines for pediatric psoriasis comorbidities

The guidelines are the first to provide recommendations for comorbidity screening in pediatric psoriasis patients.

Nodules on the scalp lead to a diagnosis of secondary syphilis

A rare case reports a 51-year-old man who primarily presented with multiple nodules on his scalp.

Herpes zoster linked to increased risk of cardiovascular events

The risks of both stroke and myocardial infarction were highest the first year after the onset of herpes zoster and decreased with time.

Bee stings and allergies: prevention and treatment tips

Symptoms of an allergic reaction to an insect sting may include itching and hives, swelling in the throat or tongue, difficulty breathing, dizziness, stomach cramps, nausea, or diarrhea.

Cardiometabolic comorbidity rates high in psoriasis patients

The most common comorbidities found in patients with psoriasis are hyperlipidemia, hypertension, depression, type 2 diabetes mellitus, and obesity.

Biologic treatment for psoriasis shows long-term effectiveness

Researchers sought to analyze long-term and real-world outcome data in patients with moderate-to-severe psoriasis after starting biologic treatment.

Antibiotics improve short-term outcomes in small skin abscesses

Antibiotics in conjunction with incision and drainage improved short-term outcomes compared with incision and drainage alone.

Emergency department visits for herpes zoster increased from 2006-2013

The number of emergency department visits for herpes zoster have increased from 2006 to 2013.

Tofacitinib linked to improvements in nail psoriasis

Treatment resulted in improvements in nail psoriasis vs placebo at 16 weeks.

First-line biologic treatment for psoriasis influenced by specific factors

Presence of psoriatic arthritis, weight, employment status, baseline disease severity affect the selection of first-line biologic treatment.

FDA approves Dupixent to treat moderate-to-severe eczema

Participants in clinical studies who received Dupixent achieved clear or almost clear skin and a reduction in itch after 16 weeks of treatment.

FDA approves Siliq for treatment of plaque psoriasis

The injected medication has been approved for use by patients who have failed to respond to other systemic therapies.

Wart lesions: intralesional immunotherapy more effective than cryotherapy

Patients exhibited a significant therapeutic response to immunotherapy compared with cryotherapy.

Food additives may affect recurrent aphthous stomatitis

Participants underwent patch testing for food in an effort to examine whether food additives play a role in recurrent aphthous stomatitis etiology.

FDA approves Eucrisa for eczema treatment

In a controlled trial, participants receiving Eucrisa achieved clear or almost clear skin after 28 days of treatment.

Phenotype-based treatments recommended for rosacea

Phenotype-based treatments are recommended for presenting signs and symptoms of rosacea.

Prescription treatments are more effective in head lice treatment

Over-the-counted remedies are not as effective as prescription medications.

FDA approves over-the-counter Differin Gel 0.1% to treat acne

Differin Gell 0.1% (adapalene) is the first retinoid approved for over-the-counter treatment of acne by the FDA.

Routine primary care screening improves detection of melanomas

Primary care screening can help patients avoid the need for more aggressive therapy and potentially save lives.

Patients with psoriasis have an increased risk of abdominal aortic aneurysm

Patients with psoriasis are more likely to have an abdominal aortic aneurysm, with the likelihood increasing with more severe psoriasis.

Limited data on molluscum contagiosum treatment in HIV

Overall quality of the studies reviewed was poor, leaving gaps in the development treatment recommendations for MC.

1 in 4 patients with infantile hemangioma experience rebound growth

Approximately a quarter of patients with infantile hemangioma experience rebound growth, which happens at a mean age of 17.1 months.

Blood test may improve advanced melanoma tracking

A new blood test assesses levels of circulating tumor DNA (ctDNA) in patients with unresectable stage IIIC/IV melanoma.

Evidence lacking to assess benefits/harm of visual skin cancer screening

The USPTF has determined that there is insufficient evidence for the harms and benefits of visual skin cancer screening.

Brand-name, generic dermatologic drug prices increasing

Escalating prices were found across all categories of dermatologic drugs, including anti-infective medications and treatments for psoriasis and rosacea.

El Niño linked to rise in a range of dermatologic conditions

El Nino and La Nina have been linked to increases in actinic keratosis, rosacea, dermatitis, psoriasis, and varicella, among other dermatologic conditions.

Brodalumab, secukinumab show efficacy for psoriasis treatment

Two studies indicate that brodalumab and secukinumab had significant benefits for patients with psoriasis or psoriatic arthritis.

Patients with rosacea at risk for various comorbid conditions

Researchers found a significant link between moderate to severe rosacea and many comorbid conditions.

Increased risk for arrhythmia in psoriasis patients

Patients with psoriasis, especially those with psoriatic arthritis, have an increased risk of arrhythmia.

Laser technique accurately identifies melanoma

A non-invasive laser test can accurately identify melanoma with 100% accuracy.

Fewer moles linked to more aggressive melanoma

Many moles increases melanoma risk, but fewer moles are linked to more aggressive forms of melanoma.

Combination glycolic acid, iontophoresis therapy effective for acne

Combination therapy of glycolic acid peels and iontophoresis with vitamins A, C, and E effectively treats acne.

FDA approves new rosacea treatment

The FDA has approved Finacea Foam for the topical treatment of rosacea.

Psoriasis increases depression risk in women

Women with psoriasis and psoriatic arthritis have an increased risk of depression.

Hazardous sunburn art trend popular on social media

Clinicians should warn patients about the dangers of sunburn and discourage this new trend.

Physical trauma increases psoriatic arthritis risk

Psoriasis patients exposed to trauma have an increased risk for psoriatic arthritis.

Ixekizumab quickly, effectively treats psoriasis

The monoclonal antibody ixekizumab was more effective than other treatments for treating psoriasis.

Novel drug may be effective for psoriasis

Guselkumab was more effective than standard psoriasis treatment but had higher rates of pneumonia.

Lower zinc levels linked to more severe alopecia

Patients with alopecia areata have lower serum zinc levels compared with controls.

New diagnosis of psoriatic arthritis predicts cardiovascular disease

People with newly diagnosed psoriatic arthritis have an increased risk of later CVD.

Janus kinase inhibitors may treat vitiligo

Janus kinase inhibitors are indicated for rheumatoid arthritis, but they may be able to treat vitiligo.

Inpatient consultation can reduce cellulitis misdiagnosis

Most patients who were initially diagnosed with cellulitis were diagnosed with pseudocellulitis in inpatient settings.

Psoriasis drug may also aid weight loss

Nearly 20% of patients lost more than 5% of their baseline weight by 52 weeks or less when assigned to receive apremilast.

Additional evidence of link between psoriasis, kidney disease

Patients with psoriasis should avoid long-term use of medications that are toxic to the kidneys.

Biologic therapy may be safe for hemodialysis patients with psoriasis

Patient with psoriasis were unsuccessfully treated with conventional therapies before treatment with biologics.

Psoriasis not independent risk factor for heart disease

Patients with psoriasis do not have an increased of major cardiovascular events like heart attack and stroke.

Adalimumab clears psoriasis faster than traditional treatment

Patients taking adalimumab saw quicker treatment of their psoriasis than those taking methotrexate.

Melanoma rates among kids, young adults, on the rise

While women accounted for 57% of melanomas reported between 1973 and 1980, they comprised about 65% of all diagnoses by 2011.

Clindamycin, trimethoprim-sulfamethoxazole have similar success for skin infections

A study suggests that clindamycin and TMP-SMX are equally effective for treating uncomplicated skin infections in adults and children.

Possible link between male sex hormones, psoriasis severity

Male patients with psoriasis have higher levels of estradiol and lower levels of testosterone compared with controls.

Insulin resistance not associated with post-adolescent acne

The homeostasis model assessment of insulin resistance index did not differ significantly for patients with post-adolescent acne and controls.

Acne history linked with increased melanoma risk

After adjustment for known risk factors, increased relative risk for women with history of acne.

Phase 1 trial results favorable for new psoriasis drug

The rate of reported adverse events was comparable in both the treatment and placebo groups.

Combination psoriasis treatments lack efficacy, safety information

The preferred order for combining a second modality with biologics is biologic and methotrexate combination, biologic and acitretin combination, and then biologic and phototherapy combination.

Therapeutic silencing of IL-23 may treat psoriasis

These study findings confirm that the therapeutic silencing of IL-23 is a potential target for psoriasis prevention and management.

Integrating alternative medicine, psoriasis treatment

Consistent evidence supports the use of fish oil supplementation. Zinc supplementation, however, has not been proven effective.

Psoriasis negatively affects sexual health

Of the patients, 38% (n=134) reported current genital involvement while 64% (n=224) had a current and/or previous history of genital involvement.

Sleep apnea could raise psoriasis risk in women

The presence of snoring was not associated with a higher risk of psoriasis.

Researchers identify gene that causes psoriatic arthritis

This discovery could prevent progression of psoriatic arthritis in patients with psoriasis.

Methotrexate, cyclosporine among most affordable psoriasis treatments

Infliximab and ustekinumab 90 mg were the most costly therapies.

Phase 1 trial results favorable for experimental psoriasis drug

The 31 patients who received BI 655066 had clinical improvement beginning at week 2 and maintained through week 66 weeks.

H. Pylori may affect psoriasis severity

The prevalence of H. pylori was not higher in psoriasis versus the control, but patients infected with H. pylori showed more severe psoriasis compared with uninfected patients.

Regular over-the-counter pain med use may up psoriasis, psoriatic arthritis risk

Long-term use of medications such as acetaminophen, ibuprofen, and aspirin may double a patient's risk of developing psoriatic arthritis.

Most psoriasis patients being treated accordingly

Providers may have not made changes to treatment strategies due to the high effectiveness of biologics in most visits.

New hypersensitivity/allergic disease model proposed

The proposed model has been presented to the World Health Organization groups in charge of International Classification of Diseases (ICD-11) revision.

Eczema major U.S. health, cost burden

Adults with eczema had $371 to $489 higher out-of-pocket costs per person-year compared with those without the disease.

Anti-TNF alpha drugs rarely cause lupus flares in patients with psoriasis, lupus

The coexistence of psoriasis with lupus erythematosus is rare and often presents a therapeutic challenge.

Human breast milk effective infant atopic dermatitis treatment

Human breast milk can improve infant atopic eczema with the same results as 1% hydrocortisone ointment, according to researchers.

Consider Achilles arthropathy in asymptomatic patients with psoriasis

The initial site of articular inflammation is where the Achilles tendon attaches to the bone.

Fumaric acid esters effective psoriasis treatment in Germany

The long-term safety profile of continuous fumaric acid esters treatment is favorable.

Psoriasis patients less likely to exercise

Less likely to engage in moderate to vigorous physical activity, especially those with severe disease

Tonsillectomy may improve psoriasis symptoms in select patients

The causative link between chronic tonsillitis and psoriasis have been mostly speculative based on translational association studies.

Secukinumab earns FDA approval for plaque psoriasis

Secukinumab has been approved by the FDA for the treatment of moderate to severe plaque psoriasis in adult patients who are candidates for systemic therapy or phototherapy.

Coffee may lower melanoma risk

People who drank one to three cups a day had about a 10% decreased risk of melanoma compared with those who drank none at all.

Teenage acne, melanoma link identified in women

Among women with a history of severe teenage acne, the relative risk increased for melanoma even after adjustment for previously known risk factors.

Education needed for cardiovascular risks linked to psoriasis, PsA

Educational programs may improve cardiovascular and metabolic risk management in patients.

Biologic monotherapy more effective combination Tx in psoriasis patients

Agents in biologic monotherapy target key processes in the pathogenesis of psoriasis, therefore offering better efficacy than current biologic and systemic therapies.

Psoriasis may cost United States $135 billion each year

Direct costs of psoriasis ranged from $51.7 billion to $63.2 billion, and indirect costs ranged from $23.9 billion to $35.4 billion.

Emphasize lifestyle behavior changes for patients with psoriasis

Clinicians who treat patients with psoriasis may need additional training in lifestyle behavior modification initiatives.

Diet, alcohol consumption effect psoriasis symptoms

Overweight and obese psoriasis patients should to lose weight and increase physical activity as a way to improve psoriasis symptoms.

Bacterial skin/skin structure treatment

Dalvance is used to treat acute ­bacterial skin and skin structure infections (ABSSSI) that have been caused by certain susceptible Gram-positive organisms.

Psoriasis linked to increased chronic kidney disease, glomerulonephritis risk

The increased risk of CKD and GN was seen in patients with both mild and severe psoriasis.

Indoor tanning-related emergency department visits drop

The decreasing popularity of tanning salons may be a contributing factor to the drop of emergency care visits because of overexposure to UV radiation.

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