Dermatology

Gene therapy for ichthyosis or pityriasis rubra pilaris?

March 18, 2010

Ichthyosis and pityriasis rubra pilaris are very difficult conditions for a child to deal with emotionally and physically.
 

What to look for with 
drug-induced urticaria

Natasha Casie Chetty, MD, and Clive E.H. Grattan, MD March 01, 2010

An accurate diagnosis is crucial. It is necessary to know which related drugs need to be avoided, as well as alternative drugs to recommend for patients.
 

Purple eruptions

Noah S. Scheinfeld, MD, JD March 01, 2010

Two patients with purple lesions and no other abnormal skin findings.
 

Painful tightening 
of the skin on the legs

Michael Sonabend, MD March 01, 2010

A 62-year-old man with a painful erythematous rash on the shins
 

Atrophic rash in a 
patient with hepatitis C

Laura McGevna, MD, and Robert Scott Nelson, MD March 01, 2010

Plaques develop on the face, trunk, and hands of a man with hepatitis C.
 

Erythematous truncal plaques

Sean D. Doherty, MD February 04, 2010

Two patients with erythematous trunk plaques—the first developed eight months earlier, and the other 15 years ago.
 

Pressure-induced bumps and erythema

Craig G. Burkhart, MD, MPH February 04, 2010

A man presents with complaints of itchy and uncomfortable red bumps on his skin at sites of pressure. The lesions typically dissipated after one hour.
 

Topical treatment turns ulcer pruritic

Rajani Katta, MD, and Vijayalaxmi Anusuri, MBBS February 04, 2010

A woman develops severe itching and burning two days after application of topical bacitracin and a compression bandage to a venous stasis ulcer.
 

Biologics revolutionize psoriasis management

By Noah Scheinfeld, MD, JD, and Maryann Mikhail January 21, 2010

Biologic agents, some of them already used for arthritis, are proving highly effective against this disfiguring disease. But there's a downside: high cost.
 

Lung infiltrates complicate a common rash

Case and Analysis by Kirk M. Chan-Tack, MD, and Edward Adelstein, MD January 20, 2010

The vesicular rash spread rapidly from the face and mouth to cover the chest, back, arms, legs, and feet.
 

Headache, fever, and joint pain accompanied by a facial rash

Amy Waggner, CFNP January 12, 2010

Was the unusual presentation of this nurse's symptoms caused by a fungal infection or something more common?
 

Vesiculobullous eruptions

Stanley Chan, MD January 08, 2010

Two patients present with similar vesiculobullous eruptions. One was preceded by painful mouth sores, the other had no oral involvement.
 

White areas on the face of a teenager

Craig G. Burkhart, MD, MPH January 06, 2010

Fearing a bacterial infection, a teenager seeks treatment for white facial patches.
 

Brown recluse spider bite

Matthew Brier, MD, MPH January 05, 2010

Fatalities are rare, but bites are most dangerous to young children, the elderly, and those in poor physical condition.
 

Reminders of sun exposure

Laura Conley and Robert L. Buka, MD December 15, 2009

Sun exposure is the common link between these two conditions. Can you tell them apart?
 

Persistent plaque with severe intermittent pruritus

By Craig G. Burkhart, MD, MPH December 15, 2009

Intermittent itching accompanies a persistent leg plaque.
 

Herpes zoster risk in an infant

December 11, 2009

What is the best way to prevent transmission of the varicella-zoster virus?
 

Nonhealing painless ulcer on the sole

Michael L. Sonabend, MD, Nicholas R. Snavely, MD, and Sylvia Hsu, MD December 10, 2009

For three years, the patient lived with an enlarging painless ulcer on the sole of his foot. The lesion occasionally drained liquid but never became red or tender.
 

Brown bumps that evolved into verrucous plaques

Mandy Harting, MD December 10, 2009

The asymptomatic rash on a young woman's chest and back appeared to be spreading. Hyperpigmented papules had become larger verrucous plaques.
 

Shingles can be treated—and now prevented

Jeffrey M. Weinberg, MD December 04, 2009

Older patients are at greatest risk for debilitating postherpetic neuralgia, but antiviral therapies ease the pain, and a new vaccine offers hope of prevention.
 

Can you identify these similar scalp nodules?

Deborah J. Yang, MD December 01, 2009

Two women present with growing scalp nodules. One patient reported recent unintentional weight loss.
 

Errors lead to undiagnosed melanoma

By Ann W. Latner, JD November 16, 2009

After referring his patient to a dermatologist to have a mole looked at, the clinician considered the case resolved. Not so fast.
 

Coalescing purpuric plaques

Noah S. Scheinfeld, MD, JD November 10, 2009

Can you distinguish between two purpuric plaques on patients' legs?
 

Tongue plaque with offensive odor

Robert L. Buka, md November 10, 2009

The patient is concerned about a recent increase in his foul-smelling tongue discoloration.
 

Recurrent periorbital dermatitis

November 05, 2009

A routinely developing reddish, bilateral, slightly papular rash on the lower eyelids resolves with OTC hydrocortisone but reappears.
 

Irregular purplish blue markings on the limbs of a newborn

Jennifer Smith, MSN, ACNP November 05, 2009

Blue markings on the arm and leg of a newborn were first thought to be bruises from a traumatic delivery.
 

Target lesions in a patient with acne

Craig G. Burkhart, MD, MPH November 05, 2009

Numerous red target lesions develop on the extremities of a young woman being treated for acne.
 

A pair of generalized red rashes

Noah S. Scheinfeld, MD, JD November 03, 2009

Two men present with red rashes—one started on the back and spread to the upper arms, and the other was limited to the chest.
 

Colloidal silver—science or fraud?

Sherril Sego, MSN, FNP November 03, 2009

While topical and implanted silver products are safe, there is no clinical indication for oral colloidal silver use.
 

Recurrent cellulitis following buttock augmentation

Erica Kass, MD, and Eugene Wong, MD November 03, 2009

The patient's pain and swelling failed to resolve despite previous hospitalization and IV cephalosporin therapy.
 

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