Diabetes News Archive

Empagliflozin Reduces Risk for Nephropathy Regardless of Blood Pressure, LDL Cholesterol, HbA1c

Investigators examined renal outcomes when controlling cardiovascular risk factors, such as blood pressure, LDL-C, and HbA1c.

Risk for Below Knee Amputations With Canagliflozin vs Other Antihyperglycemic Agents

Investigators analyzed real world data to examine the risk for below-knee amputations in patients with type 2 diabetes taking canagliflozin vs other medications.

Beta-Blockers Show Varied Effects on Hypoglycemic Mortality Risk in Diabetes

Investigators examined the relationship between the use of β-blockers and incidence of hypoglycemia and risk for mortality in hospitalized patients with diabetes.

Pen vs Patch Bolus Insulin Delivery for T2D Using CGM

Investigators compared 2 methods of delivering bolus insulin, pen vs patch, using metrics from continuous glucose monitoring.

Liraglutide May Prevent Dementia in Elderly With Type 2 Diabetes

Investigators examined the efficacy of liraglutide for the prevention of dementia in elderly patients with type 2 diabetes.

Age, Baseline HbA1c May Predict Glycemic Control in Newly Diagnosed Type 2 Diabetes

Investigators examined the effectiveness of oral agents vs insulin as an initial treatment option for people newly diagnosed with type 2 diabetes.

Elevated Triglycerides, Diabetes May Be Predictors of Major Cardiovascular Events

Investigators examined cardiovascular outcomes in patients with elevated triglyceridemia and diabetes treated with statins.

Safety and Performance of Omnipod HCL for Children With Type 1 Diabetes

In children with type 1 diabetes, the Omnipod hybrid closed-loop personal model system was safe and performed well.

Type 2 Diabetes Does Not Affect Pneumonia Incidence, Outcomes After Stroke

Investigators examined the incidence and outcomes of pneumonia in patients with acute ischemic stroke and type 2 diabetes.

ITCA 650 Shows Efficacy in Reducing Weight, HbA1c in Type 2 Diabetes

The ITCA 650, a small titanium osmotic mini-pump, provides a subcutaneous infusion of exenatide over 3 or 6 months.

MEDI0382 Safe, Effective for Normalizing Glucose, Weight Loss in Type 2 Diabetes

MEDI0382 reduced body weight and normalized fasting and postprandial blood glucose levels in patients with type 2 diabetes.

Chronic Kidney Disease More Common in Type 2 Diabetes Than in Type 1 Diabetes

Investigators examined the prevalence of chronic kidney disease in adults with type 1 diabetes compared with type 2 diabetes.

Implantable Continuous Glucose Monitoring Device Safe, Effective for Adolescents

The safety assessment included incidence of insertion or procedure-related removal and device-related serious adverse events through 180 after insertion.

BCG Vaccine Tied to Reduced Hyperglycemia in Type 1 Diabetes

Systemic shift in glucose metabolism from oxidative phosphorylation to aerobic glycolysis.

Cleared Blood Glucose Monitor Systems Not Always Accurate

Six of 18 systems met predetermined accuracy standard in three of three studies

Sodium Chloride Fluid Infusion Rates Do Not Affect Pediatric Diabetic Ketoacidosis

Sodium chloride content of intravenous fluids does not affect neurologic events in children with diabetic ketoacidosis.

Long-Term Type 1 Diabetes Associated With Cognitive Decline

Deficits similar for long-term type 1 diabetes and age-matched patients with type 2 diabetes

Cancer Development Linked to Increased Diabetes Risk

Increased risk of subsequent diabetes independent of traditional diabetes risk factors

More Rapid Decline in Kidney Function for Diagnosed Diabetes

Much steeper decline in adjusted mean eGFR for those with diagnosed diabetes versus those without

Improving Insulin Access: ADA Public Policy Recommendations

The American Diabetes Association (ADA) has released a public policy statement that outlines long- and short-term recommendations for improving insulin affordability.

US Nursing Home Costs Due to Diabetes Vary Greatly by State

Per-person diabetes-attributable costs ranged from 374 in New Mexico to 1,610 in Washington, D.C.

Diabetes and Mortality: Comparing SGLT-2 Inhibitors, GLP-1 Agonists, and DPP-4 Inhibitors

For patients with type 2 diabetes, sodium-glucose cotransporter 2 inhibitors and glucagon-like peptide 1 agonists significantly reduce mortality rates compared with dipeptidyl peptidase 4 inhibitors.

Diabetes Prevalence by Type in the United States: CDC report

The CDC conducted a study to estimate the prevalence of diagnosed diabetes among adults in 2016 by primary type.

FDA Approves AI Device to Detect Diabetic Retinopathy

Artificial intelligence software that can detect diabetic retinopathy has been approved by the U.S. Food and Drug Administration.

Eating Pecans May Cut Risk of Cardiovascular Disease, Diabetes

Benefits seen in markers of cardiometabolic disease, including insulin sensitivity

ACP supports higher HbA1c targets for pharmacotherapy in adults with T2D

ACP responds to criticism from the ADA, the Endocrine Society, the AACE, and the AADE of guidance that clinicians should aim to achieve an HbA1c level between 7% and 8% in most people with type 2 diabetes.

Early Care Transitions Beneficial for Adolescents with Type 1 Diabetes

A diabetes transition registry may help adolescents with type 1 diabetes plan and prepare for independent adult care.

Better glycemic control, weight reduction with surgical treatment for youths with T2D, severe obesity

For adolescents with type 2 diabetes and severe obesity, surgical therapy facilitates glycemic control and weight reduction better than medical therapy.

High fiber diet beneficial for gut bacteria development in type 2 diabetes

A high fiber diet promotes gut bacteria that helps blood glucose control in patients with type 2 diabetes.

New type 2 diabetes guideline recommends more moderate HbA1c target

The American College of Physicians has developed recommendation statements to guide clinicians in selecting targets for pharmacologic treatment of type 2 diabetes.

HbA1C levels linked to cognitive decline in diabetes

HbA1C, diabetes status, and cognitive decline during a span of 10 years were compared using data from the English Longitudinal Study of Ageing.

Standards of Medical Care in Diabetes modified for cardiovascular disease

The ADA's updates include a modified patient-focused care algorithm as well as improved risk management for CVD.

FDA approves shock wave device to treat diabetic foot ulcers

The FDA has approved the Dermapace System for treatment of chronic, full-thickness diabetic foot ulcers.

FDA approves new "follow-on" insulin for diabetes

The new FDA approved short-acting insulin drug can be used to treat T1 and T2 diabetes.

Type 2 diabetes may be reversed with weight loss, physician care

With the help of a doctor and a weight loss plan, new research suggests type 2 diabetes can be reversed in less than a year.

FDA approves weekly diabetes drug that may also be beneficial for weight loss

The FDA has approved semaglutide injection as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Oral insulin does not prevent type 1 diabetes in relatives of patients

Oral insulin usage does not prevent the development of type 1 diabetes in relatives of patients.

Commercial weight loss program may help prevent diabetes in obese patients

Primary care referral to Weight Watchers meetings is associated with weight loss, HbA1c reduction.

Statins associated with increased risk of diabetes in high-risk individuals

Statins are associated with an increased risk for developing type 2 diabetes, especially for high-risk individuals.

Halloween tips for children with diabetes

With a little creativity, children with diabetes can enjoy the festivities of Halloween.

Antidepressant use linked to type 2 diabetes in young adults

Type 2 diabetes risk is increased in young adults through antidepressant use, specifically the duration of use and the cumulative dose.

Diabetes risk greater in children, young adults on second-generation antipsychotics

Type 2 diabetes is greater with second-generation antipsychotics than with non-second-generation antipsychotic psychotropic medications for patients aged 6 to 25 years.

Insulin pump linked to better glycemic control in young patients with type 1 diabetes

Insulin pump therapy is linked to lower risks of severe hypoglycemia and diabetic ketoacidosis and better glycemic control than insulin injection therapy.

FDA approves glucose monitoring system to eliminate fingerstick testing

The system uses a small sensor implanted below the skin and a mobile reader to continuously monitor blood glucose.

Evidence finds link between antidepressant drug use and type 2 diabetes

After the inclusion of recent negative studies, a statistically significant association between AD use and diabetes was observed.

Gastric bypass surgery effective for weight loss, diabetes prevention for 12 years

The 12-year results show that Roux-en-Y gastric bypass offered long-term durability of weight loss and was associated with fewer obesity-related coexisting conditions compared with those who did not have the surgery.

Managing hypertension in diabetes: a position statement from the ADA

The statement includes advances in care since the ADA's last position statement was published in 2003.

Shorter sleep duration linked to higher diabetes risk in children

Sleep duration for 1 hour longer was associated with lower BMI, fat mass, insulin resistance, and fasting glucose but had no effect on HbA1c or cardiovascular risk.

Lifestyle intervention provides minimal benefit in improving glycemic control in type 2 diabetes

Lifestyle interventions maintain glycemic control in patients with type 2 diabetes.

Regular alcohol consumption associated with lower risk of diabetes

Consumption of alcohol 3 to 4 days weekly is associated with a significantly lower risk for diabetes in men and women.

Maternal lifestyle interventions reduce the odds of cesarean section

Lifestyle interventions reduce gestational weight gain across various subgroups of women and lower the odds of cesarean section without affecting offspring outcomes.

A link between antiretroviral therapy and diabetes in HIV patients?

HIV-infected patients on ART had approximately 4 and 1.5 greater odds of developing diabetes mellitus and metabolic syndrome, respectively.

Degludec vs glargine in type 2 diabetes for cardiovascular events

Degludec is noninferior to glargine regarding the incidence of major cardiovascular events among patients with type 2 diabetes.

Side effects may affect medication nonadherence in patients with chronic disease

Almost half of participants reported that they never received information regarding the side effects of their medication from their prescriber.

Cardiometabolic Disease Staging score calculates diabetes risk in obese individuals

The score can predict the effectiveness of weight-loss therapy for preventing diabetes in overweight or obese individuals.

Depression among diabetes patients may affect long-term drug adherence

Patients exhibiting moderate-to-severe depressive symptoms had worse adherence than nondepressed patients.

Probiotics may lower risk of gestational diabetes

Women who took probiotics in their second trimester had lower rates of gestational diabetes.

Using information technology to tailor diabetes care

A study of one tracking system's effect finds improvement in the management of diabetes.

Anti-inflammatory effects of linagliptin in diabetes patients

Patients taking linagliptin had decreased HbA1c as well as reactive oxygen species generation and plasma lipid peroxide levels.

Insulin pump therapy improves quality of life in adolescents with type 2 diabetes

Adolescents with type 2 diabetes decreased HbA1c levels after using insulin pump therapy for a 3-month period.

Diabetes and glucose intolerance increase with higher outdoor temperature

Diabetes incidence rates in the US and glucose intolerance worldwide increased per 1°C increase in temperature.

Insulin initiation in primary care improves HbA1c levels

The Stepping Up model of care produced a clinically and significantly significant improvement in HbA1c among adults with type 2 diabetes managed in primary care.

Gluten-free diet may increase risk of type 2 diabetes

Individuals who consume the least amount of gluten are more likely to develop type 2 diabetes.

Metformin, vildagliptin have differing effects on heart rate, blood pressure in diabetes

Vildagliptin lowers blood pressure and elevates heart rate, while metformin increases heart rate with no effect on blood pressure.

Managing diabetic retinopathy: ADA releases new position statement

The position statement by the ADA incorporates updates in treatment and screening for patients with diabetic retinopathy.

Depression is often untreated in dialysis patients

Depression is common in patients receiving chronic hemodialysis but seems to be ineffectively treated.

Novel oral glucose lowering drugs reduce adverse events in type 2 diabetes

Researchers observed a reduced risk of all-cause mortality and CVD with dapagliflozin and a lower risk of mortality with dipeptidyl-peptidase-4 inhibitors.

Diabetes without insulin may not increase thromboembolic risk in atrial fibrillation

Diabetes without insulin did not appear to increase thromboembolic risk in patients with atrial fibrillation treated with anticoagulation.

The 2017 Standards of Medical Care in Diabetes: an update from the ADA

The document addresses important new issues in diabetes management, including metabolic surgery and a more specific definition of hypoglycemia.

CDC tips for prediabetes prevention and treatment

Prediabetes does not always show clear symptoms; however, it can lead to type 2 diabetes, heart disease, or stroke.

Risk for postpartum depression higher among women with diabetes

Among all women, PPD risk increased with advanced age and gestational diabetes.

Accuracy of prediabetes screening tests is low

Fasting glucose is specific but not sensitive, and HbA1c is neither sensitive nor specific.

Glyburide and metformin have similar glucose control in gestational diabetes

Researchers observed a high efficacy rate for both glyburide and metformin.

Mortality risk increased in type 2 diabetes with depression or anxiety

Men with diabetes, but not women, had excess mortality risk associated with depression and anxiety.

Enterovirus infections associated with autoimmunity in type 1 diabetes

The most frequent enterovirus types included coxsackievirus A4, coxsackievirus A2, and coxsackievirus A16.

Fish oil, aspirin ineffective for reducing arteriovenous fistula failure

The study suggests that neither fish oil nor aspirin can be recommended for the prevention of AVF failure.

Updated guideline for oral pharmacologic treatment of type 2 diabetes

The ACP has updated the 2012 guideline to provide clinical recommendations of oral pharmacologic treatment of type 2 diabetes.

FDA approves first continuous glucose monitoring system to replace fingerstick test in diabetes

The FDA has approved a continuous glucose monitoring system to replace fingerstick blood sugar testing in patients with diabetes.

Primary care clinician volume tied to quality of diabetes care

Higher ambulatory volume was linked to lower quality of care and quality increased with higher diabetes-specific volume.

ADA releases guidelines for psychosocial care for diabetes patients

The position statement provides recommendations for psychosocial assessment and care of individuals with diabetes.

Gastrointestinal adverse events increase with GLP-1 receptor agonists

Risk was dependent on dose, background medications, and type of GLP-1 receptor agonist.

New continuous glucose monitoring system safe and accurate

The continuous glucose monitoring system detected 81% of hypoglycemic events within 30 minutes.

Diabetic peripheral neuropathy: an overview

Often underreported and undertreated, outcomes can be improved in this condition with appropriate screening and diagnosis.

Deferred revascularization leads to poor results in diabetes

Combining FFR with imaging techniques may be required to guide the treatment strategy in patients with high-risk, fast-progressing atherosclerosis.

ADA issues new diabetes guidelines for physical activity and exercise

The ADA releases its first independent recommendations on physical activity and exercise for all patients with diabetes.

Resveratrol supplementation shows no sign of improving insulin sensitivity

Hepatic and peripheral insulin sensitivity in patients with type 2 diabetes were not affected by resveratrol treatment.

Vitamin D may not improve glucose measures in patients at risk for diabetes

Researchers observed significant improvement in LDL cholesterol in those at risk for diabetes.

Stepwise diabetes prevention effective in patients with prediabetes

Individuals with prediabetes may reduce their risk of diabetes with stepwise diabetes prevention.

Oily fish consumption may lower diabetic retinopathy risk in type 2 diabetes

A target intake of at least 500 mg/d is recommended to combat sight-threatening diabetic retinopathy.

Drug may slow renal disease progression in type 2 diabetes

Canagliflozin 100 mg or 300 mg slowed kidney decline compared with glimepiride.

Blood pressure lower than recommended level is beneficial in type 2 diabetes

Patients with type 2 diabetes with systolic blood pressure lower than 140 mm Hg have a lower risk of cardiovascular events.

Adlyxin approved for type 2 diabetes

The once-daily injection works to improve glycemic control.

To combat prediabetes, brisk walking may be superior to jogging

Patients with prediabetes who briskly walked saw greater improvements in oral glucose tolerance compared with those who jogged.

Diabetes drugs similar regarding cardiovascular and all-cause mortality risk

A meta-analysis of the 9 classes of glucose-lowering drugs supports the ADA's recommendation of metformin monotherapy as preferred initial treatment.

Postpartum readmission rates increase

Readmission was more common among publically insured, black patients presenting with comorbidities including hypertension and diabetes.

Whole grain consumption reduces chronic disease, all-cause mortality

Reductions in disease risk were observed for an intake as high as 7.5 servings of whole grains per day.

Coronary artery bypass linked to new-onset diabetes

Coronary artery bypass surgery may lead to metabolic changes, causing new-onset diabetes.

Glucommander linked to improved blood glucose levels

Use of the Glucommander was linked to a shorter time to achieving blood glucose levels lower than 200 mg/dL.

New guidelines support use of metabolic surgery as standard treatment option for type 2 diabetes, obesity

A panel of experts has recommended that metabolic surgery be included as a treatment option for patients with type 2 diabetes and obesity.

Oral glucocorticoid use increases risk of diabetes in patients with rheumatoid arthritis

Glucocorticoid therapy in patients with rheumatoid arthritis has been linked to elevated risk of diabetes.

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