Generic Name and Formulations:
Digoxin Immune Fab (ovine) 40mg/vial; IV inj after reconstitution; preservative-free.
Indications for DIGIFAB:
Digoxin toxicity or overdose.
Adults and Children:
See literature. Dose based on amount of digoxin or digitoxin to be neutralized. Contents of 1 vial neutralizes 0.5mg digoxin.
Previous allergies to antibiotics, sheep antibodies, papain or papaya extracts. Monitor potassium, renal, and cardiac function. Postpone redigitalization until Fab fragments cleared. Interferes with digitalis immunoassays. Pregnancy (Cat.C). Nursing mothers.
Symptoms of digoxin withdrawal. Hypokalemia.