Although ovarian cancer risk may be reduced with regular use of low-dose aspirin, the use of nonaspirin analgesics may increase the risk of ovarian cancer among long-term, high-quantity users.
The infection developed within several months of the patients starting SGLT2 therapy and the drug was discontinued in most cases. All patients required surgery and there was 1 reported death.
Rate of incident pneumonia increased in second year after initiating treatment with proton pump inhibitors.
The NDA included data from two Phase 3 clinical trials (VENUS I and VENUS II), all four Phase 3 European Union registration studies, and real-world data of >700,000 women with uterine fibroids across 80 countries.
Results showed an increased risk of bleeding with SRIs by 1.16-2.36 times with an even higher 3.17- to 10.9-fold risk with concomitant NSAIDs.
Cleft lip and palate is defined as congenital malformation of the upper lip and/or oral cavity disrupting normal facial structure and oromotor function.
Heat-stable carbetocin — an analog of oxytocin — was found to be noninferior to oxytocin in preventing hemorrhage associated with vaginal birth and may be beneficial in low- and middle-income countries.
Metformin use during the first trimester of pregnancy is not correlated with an increased risk of congenital anomalies.
No increased risk of depression or suicidal ideation among persons living with HIV in Uganda.
A meta-analysis of 18 studies examining the association of prenatal antidepressant exposure with motor development in children showed a small overall effect of worse motor development outcomes among children exposed to antidepressants in pregnancy.
In this cross-sectional study, the use of medications with depression as an adverse effect was associated with a higher prevalence of depression while a similar association was not observed for medications without depression as a possible side effect.
The broad use of antidepressants among the general population may be linked to weight gain.
In a case study, olaparib was found to induce folate deficiency in most patients with relapsed ovarian cancer. Researchers discuss the significance of this adverse effect and how it was managed.
The Agency has received reports of serious neural tube birth defects involving the brain, spine, and spinal cord in babies born to women who received dolutegravir for HIV treatment.
Advances in new reversal agents will be key for managing patients treated with DOACs to prevent major bleeding events.
In patients with mild Alzheimer's disease solanezumab, an antibody designed to facilitate clearance of amyloid-beta plaques, did not significantly reduce cognitive decline over time.
A higher incidence of subdural hematomas is associated with the increased use of antithrombotic drugs, particularly vitamin k antagonists among older patients.
Cannabis health end points include therapeutic effects, cardiometabolic risk, mental health, respiratory disease, and substance abuse.
The potency of synthetic cannabinoids is consistent with strong depressant effects that account for "zombie-like" behavior.
Grapefruit can safely be consumed with the majority of medications, and patients with concerns should consult with their physicians.
Research suggests that injecting lidocaine with epinephrine may not be as dangerous as previously thought.
A patient was diagnosed with a serum sickness-like reaction in response to antibiotics.
A Bronx jury awarded close to $120 million to a woman who suffered brain damage after being treated at three New York area hospitals.
Taking boceprevir with ritonavir-boosted HIV protease inhibitors together reduces the effectiveness of both therapies, the FDA announced.
What are the differential diagnoses for a woman aged 60 years with a metallic taste in her mouth and the sensation of a burning tongue?
A patient taking terbinafine for onychogryphosis developed a fine pruritic rash over sun exposed body areas while on vacation. Could the drug be to blame?
Read this tip for making abstract concepts, like converting metric medication doses, go down smoothly.
The FDA is updating boxed warnings on all tumor necrosis factor-alpha inhibiting drugs to reflect risk for infection with the bacteria Legionella and Listeria.
The FDA is warning health care providers about reports of type 1 hypersensitivity reactions among patients taking the antipsychotic asenapine maleate (Saphris), with some cases occurring at first dose.