Endocrinology

Continuous Subcutaneous Insulin Infusion May Reduce Basal Hyperglycemia in T2D

Continuous Subcutaneous Insulin Infusion May Reduce Basal Hyperglycemia in T2D

Patients with type 2 diabetes who were initially treated with multiple daily injections were assessed before and after switching to continuous subcutaneous insulin infusion.

Elevated Triglycerides, Diabetes May Be Predictors of Major Cardiovascular Events

Elevated Triglycerides, Diabetes May Be Predictors of Major Cardiovascular Events

Investigators examined cardiovascular outcomes in patients with elevated triglyceridemia and diabetes treated with statins.

Age, Baseline HbA1c May Predict Glycemic Control in Newly Diagnosed Type 2 Diabetes

Age, Baseline HbA1c May Predict Glycemic Control in Newly Diagnosed Type 2 Diabetes

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Investigators examined the effectiveness of oral agents vs insulin as an initial treatment option for people newly diagnosed with type 2 diabetes.

Liraglutide May Prevent Dementia in Elderly With Type 2 Diabetes

Liraglutide May Prevent Dementia in Elderly With Type 2 Diabetes

Investigators examined the efficacy of liraglutide for the prevention of dementia in elderly patients with type 2 diabetes.

Metabolic Health Predicative of Cognitive Development in Children

Metabolic Health Predicative of Cognitive Development in Children

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Researchers assessed whether current metabolic parameters are inversely associated with cognitive functioning.

Pen vs Patch Bolus Insulin Delivery for T2D Using CGM

Pen vs Patch Bolus Insulin Delivery for T2D Using CGM

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Investigators compared 2 methods of delivering bolus insulin, pen vs patch, using metrics from continuous glucose monitoring.

Cleared Blood Glucose Monitor Systems Not Always Accurate

Cleared Blood Glucose Monitor Systems Not Always Accurate

Six of 18 systems met predetermined accuracy standard in three of three studies

Sodium Chloride Fluid Infusion Rates Do Not Affect Pediatric Diabetic Ketoacidosis

Sodium Chloride Fluid Infusion Rates Do Not Affect Pediatric Diabetic Ketoacidosis

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Sodium chloride content of intravenous fluids does not affect neurologic events in children with diabetic ketoacidosis.

Maternal Glucose, Fetal Genotype Independently Affect Birth Weight

Maternal Glucose, Fetal Genotype Independently Affect Birth Weight

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Fetal genetic score for birth weight affects fetal growth at various maternal fasting plasma glucose levels.

More Rapid Decline in Kidney Function for Diagnosed Diabetes

More Rapid Decline in Kidney Function for Diagnosed Diabetes

Much steeper decline in adjusted mean eGFR for those with diagnosed diabetes versus those without

Improved glycemic control in type 1 diabetics on very low-carbohydrate diets

A survey of individuals with type 1 diabetes mellitus consuming a very low-carbohydrate diet indicated that many study participants were able to maintain glycemic control within national ideal glycemic target ranges.

Updated Clinical Practice Guidelines on Testosterone Therapy in Men With Hypogonadism

Updated Clinical Practice Guidelines on Testosterone Therapy in Men With Hypogonadism

Testosterone therapy is recommended in men with hypogonadism to correct symptoms of testosterone deficiency. Men who are otherwise healthy do not need to be screened for hypogonadism.

Artificial Pancreas Systems Safe, Effective in Type 1 Diabetes

Artificial Pancreas Systems Safe, Effective in Type 1 Diabetes

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Artificial pancreas treatments are safe and effective for managing type 1 diabetes.

Diabetes and Mortality: Comparing SGLT-2 Inhibitors, GLP-1 Agonists, and DPP-4 Inhibitors

Diabetes and Mortality: Comparing SGLT-2 Inhibitors, GLP-1 Agonists, and DPP-4 Inhibitors

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For patients with type 2 diabetes, sodium-glucose cotransporter 2 inhibitors and glucagon-like peptide 1 agonists significantly reduce mortality rates compared with dipeptidyl peptidase 4 inhibitors.

Gastric bypass vs sleeve gastrectomy in morbidly obese patients

Gastric bypass vs sleeve gastrectomy in morbidly obese patients

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There is no statistically significant difference in weight loss at 5 years after laparoscopic sleeve gastrectomy vs laparoscopic Roux-en-Y gastric bypass in morbidly obese patients.

Oral insulin does not prevent type 1 diabetes in relatives of patients

Oral insulin does not prevent type 1 diabetes in relatives of patients

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Oral insulin usage does not prevent the development of type 1 diabetes in relatives of patients.

Diminished ovarian reserve not associated with infertility

Diminished ovarian reserve not associated with infertility

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Among women who are attempting to conceive naturally, diminished ovarian reserve is not associated with infertility.

AAP releases list of 5 unnecessary endocrine-related tests

AAP releases list of 5 unnecessary endocrine-related tests

The AAP Section for Endocrinology compiled the list of tests for height and puberty, which should prompt careful discussion between parents and physicians.

Hormone replacement therapy for menopause not associated with increased mortality risk

Hormone replacement therapy for menopause not associated with increased mortality risk

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The researchers found no long-term increase in either all-cause or cause-specific mortality among women who received hormone therapy for up to 5.6 years or 7.2 years, depending on the type of therapy.

Human embryo editing repairs genetic mutation that causes hypertrophic cardiomyopathy

Human embryo editing repairs genetic mutation that causes hypertrophic cardiomyopathy

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The gene-editing tool called CRISPR-Cas9 could have the potential to treat and prevent other genetic diseases.

CVD prevention: New USPSTF guidelines for lifestyle counseling

CVD prevention: New USPSTF guidelines for lifestyle counseling

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The USPSTF updated their 2012 recommendations on behavior lifestyle counseling for preventing cardiovascular disease.

Moderate weight gain in early to middle adulthood linked to increased risk of chronic diseases

Moderate weight gain in early to middle adulthood linked to increased risk of chronic diseases

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Adulthood weight gain is associated with an increased risk of major chronic diseases and mortality.

Thyroid disease associated with higher incidence of manic relapse in bipolar disorder

Thyroid disease associated with higher incidence of manic relapse in bipolar disorder

Thyroid disease may be a risk factor for manic relapse in patients with bipolar disorder.

Too much or too little gestational weight gain increases risk of adverse outcomes

Too much or too little gestational weight gain increases risk of adverse outcomes

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Gestational weight gain greater than or less than guideline recommendations is associated with an increased risk of adverse outcomes.

Screening for thyroid cancer: a recommendation statement from the USPSTF

Screening for thyroid cancer: a recommendation statement from the USPSTF

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The USPSTF recommends against screening for thyroid cancer in asymptomatic adults.

Anti-inflammatory effects of linagliptin in diabetes patients

Anti-inflammatory effects of linagliptin in diabetes patients

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Patients taking linagliptin had decreased HbA1c as well as reactive oxygen species generation and plasma lipid peroxide levels.

Insulin pump therapy improves quality of life in adolescents with type 2 diabetes

Insulin pump therapy improves quality of life in adolescents with type 2 diabetes

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Adolescents with type 2 diabetes decreased HbA1c levels after using insulin pump therapy for a 3-month period.

Lipid screening in children, adolescents: USPSTF recommendation statement

Lipid screening in children, adolescents: USPSTF recommendation statement

Current evidence is insufficient to weigh the balance of benefits and harms of screening.

Thyroid antibodies

Thyroid antibodies

When symptoms of thyroid disease are present, clinicians should check thyroid antibodies even if thyroid function is normal.

Reduced inpatient hypoglycemia with electronic glycemic management system

Reduced inpatient hypoglycemia with electronic glycemic management system

The eGMS system provides patient-specific insulin dosing.

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