Endocrinology

AAP releases list of 5 unnecessary endocrine-related tests

AAP releases list of 5 unnecessary endocrine-related tests

The AAP Section for Endocrinology compiled the list of tests for height and puberty, which should prompt careful discussion between parents and physicians.

Hormone replacement therapy for menopause not associated with increased mortality risk

Hormone replacement therapy for menopause not associated with increased mortality risk

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The researchers found no long-term increase in either all-cause or cause-specific mortality among women who received hormone therapy for up to 5.6 years or 7.2 years, depending on the type of therapy.

Human embryo editing repairs genetic mutation that causes hypertrophic cardiomyopathy

Human embryo editing repairs genetic mutation that causes hypertrophic cardiomyopathy

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The gene-editing tool called CRISPR-Cas9 could have the potential to treat and prevent other genetic diseases.

CVD prevention: New USPSTF guidelines for lifestyle counseling

CVD prevention: New USPSTF guidelines for lifestyle counseling

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The USPSTF updated their 2012 recommendations on behavior lifestyle counseling for preventing cardiovascular disease.

Moderate weight gain in early to middle adulthood linked to increased risk of chronic diseases

Moderate weight gain in early to middle adulthood linked to increased risk of chronic diseases

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Adulthood weight gain is associated with an increased risk of major chronic diseases and mortality.

Thyroid disease associated with higher incidence of manic relapse in bipolar disorder

Thyroid disease associated with higher incidence of manic relapse in bipolar disorder

Thyroid disease may be a risk factor for manic relapse in patients with bipolar disorder.

Too much or too little gestational weight gain increases risk of adverse outcomes

Too much or too little gestational weight gain increases risk of adverse outcomes

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Gestational weight gain greater than or less than guideline recommendations is associated with an increased risk of adverse outcomes.

Screening for thyroid cancer: a recommendation statement from the USPSTF

Screening for thyroid cancer: a recommendation statement from the USPSTF

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The USPSTF recommends against screening for thyroid cancer in asymptomatic adults.

Anti-inflammatory effects of linagliptin in diabetes patients

Anti-inflammatory effects of linagliptin in diabetes patients

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Patients taking linagliptin had decreased HbA1c as well as reactive oxygen species generation and plasma lipid peroxide levels.

Insulin pump therapy improves quality of life in adolescents with type 2 diabetes

Insulin pump therapy improves quality of life in adolescents with type 2 diabetes

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Adolescents with type 2 diabetes decreased HbA1c levels after using insulin pump therapy for a 3-month period.

Lipid screening in children, adolescents: USPSTF recommendation statement

Lipid screening in children, adolescents: USPSTF recommendation statement

Current evidence is insufficient to weigh the balance of benefits and harms of screening.

Thyroid antibodies

Thyroid antibodies

When symptoms of thyroid disease are present, clinicians should check thyroid antibodies even if thyroid function is normal.

Reduced inpatient hypoglycemia with electronic glycemic management system

Reduced inpatient hypoglycemia with electronic glycemic management system

The eGMS system provides patient-specific insulin dosing.

New questionnaire to guide treatment of patients with acromegaly

New questionnaire to guide treatment of patients with acromegaly

Patients with acromegaly often exhibit breakthrough symptoms, despite stable treatment.

Coronary artery bypass linked to new-onset diabetes

Coronary artery bypass linked to new-onset diabetes

Coronary artery bypass surgery may lead to metabolic changes, causing new-onset diabetes.

Glucommander linked to improved blood glucose levels

Glucommander linked to improved blood glucose levels

Use of the Glucommander was linked to a shorter time to achieving blood glucose levels lower than 200 mg/dL.

Once-weekly GLP-1RAs beneficial for type 2 diabetes

Once-weekly GLP-1RAs beneficial for type 2 diabetes

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Once-weekly GLP-1RAs reduced HbA1c and fasting plasma glucose.

Short sleep duration increases risk of metabolic syndrome

Short sleep duration increases risk of metabolic syndrome

Dose-response association, with 1.5-fold increase among those sleeping less than five hours

Prevalence of metabolic 
syndrome high but stable

Prevalence of metabolic 
syndrome high but stable

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Although many older adults have metabolic syndrome, the rates are stable.

Subclinical hypothyroidism plus statins increase diabetes risk

Subclinical hypothyroidism plus statins increase diabetes risk

Patients with subclinical hypothyroidism who take statins have an increased risk of developing diabetes.

Diabetes may increase infection-related mortality risk

Diabetes may increase infection-related mortality risk

After adjustment for age and sex, standardized mortality ratios (SMRs) were higher in type 1 and type 2 diabetes for all outcomes.

Older insulins may be option for uninsured patients with diabetes

Older insulins may be option for uninsured patients with diabetes

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Current insulin treatments and new agents to manage diabetes may be prohibitively expensive for patients without health insurance.

Strict glycemic control may decrease cardiovascular events in diabetes patients

Strict glycemic control may decrease cardiovascular events in diabetes patients

The glycated hemoglobin in the intensive control group was 6.9%, on average. For those on standard care, the glycated hemoglobin average was 8.4%.

Insulin resistance not associated with post-adolescent acne

Insulin resistance not associated with post-adolescent acne

The homeostasis model assessment of insulin resistance index did not differ significantly for patients with post-adolescent acne and controls.

Vegan diet may improve diabetic neuropathy pain

Vegan diet may improve diabetic neuropathy pain

The vegan group had lost 15 pounds, on average, versus about one pound in the comparison group.

Educate patients on SGLT2 inhibitors about yeast infection risk

Educate patients on SGLT2 inhibitors about yeast infection risk

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Patients with diabetes who are prescribed sodium glucose co-transporter type 2 inhibitors are at increased risk for developing a mycotic infection.

Iron deficiency may impact metabolic pathways

Iron deficiency may impact metabolic pathways

Iron treatment correlated with significant increases in serum folate and vitamin B12 from baseline.

Renal failure in a patient with maturity onset diabetes of the young

Renal failure in a patient with maturity onset diabetes of the young

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A patient presented to the office with a 45-year history of maturity onset diabetes of the young after renal failure.

Vitamin D aids weight loss in obese, overweight patients

Vitamin D aids weight loss in obese, overweight patients

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A significantly greater weight decrease was observed in patients assigned to receive vitamin D compared with patients who had no supplementation.

Certain gut microbes may be linked to obesity risk

Certain gut microbes may be linked to obesity risk

More than two dozen of metabolites were highly correlated with diet, and about half the molecules had not previously been linked to obesity risk.

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