Evidence-Based Medicine Articles

High-dose folic acid, vitamin B6, 
and vitamin B12 may increase adverse outcomes in patients with diabetic nephropathy

July 01, 2010

B vitamin formulations with high doses of folate have been used to reduce homocysteine levels.
 

Lactobacillus GG may decrease risk of nosocomial respiratory and GI infections in hospitalized children

July 01, 2010

Measures commonly used to prevent nosocomial infections (e.g., hand hygiene) are not completely effective.
 

Low-dose colchicine may be as effective as high-dose for acute gout flare

July 01, 2010

Low-dose colchicine was associated with fewer adverse effects.
 

Single high Dose of vitamin D3 annually increases risk of falls and fractures in elderly women

July 01, 2010

Adherence to daily supplements can be problematic for older patients.
 

Aspirin associated with reduced risk of breast cancer mortality

July 01, 2010

It has been previously suggested that aspirin use has no effect on breast cancer incidence.
 

Continuing clopidogrel plus aspirin beyond 12 months after stenting no more effective for cardiovascular outcomes 
than aspirin alone

July 01, 2010

Guidelines recommend dual-antiplatelet therapy for at least one year following placement of a drug-eluting stent.
 

Moderate alcohol consumption in women may reduce overweight or obesity

June 01, 2010

Red wine was associated with the greatest risk reduction
 

Addition of ECG to pre-participation screening can increase detection of cardiac abnormalities in athletes

June 01, 2010

ECG was also associated with an increase in false positives.
 

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