Evidence-Based Medicine

Continuing clopidogrel plus aspirin beyond 12 months after stenting no more effective for cardiovascular outcomes 
than aspirin alone

July 01, 2010

Guidelines recommend dual-antiplatelet therapy for at least one year following placement of a drug-eluting stent.
 

Aspirin associated with reduced risk of breast cancer mortality

July 01, 2010

It has been previously suggested that aspirin use has no effect on breast cancer incidence.
 

Single high Dose of vitamin D3 annually increases risk of falls and fractures in elderly women

July 01, 2010

Adherence to daily supplements can be problematic for older patients.
 

Low-dose colchicine may be as effective as high-dose for acute gout flare

July 01, 2010

Low-dose colchicine was associated with fewer adverse effects.
 

Lactobacillus GG may decrease risk of nosocomial respiratory and GI infections in hospitalized children

July 01, 2010

Measures commonly used to prevent nosocomial infections (e.g., hand hygiene) are not completely effective.
 

High-dose folic acid, vitamin B6, 
and vitamin B12 may increase adverse outcomes in patients with diabetic nephropathy

July 01, 2010

B vitamin formulations with high doses of folate have been used to reduce homocysteine levels.
 

Rifaximin may improve remission 
and reduce hospitalization 
for hepatic encephalopathy

June 01, 2010

Hepatic encephalopathy is a common complication of liver cirrhosis.
 

Questionnaire may detect major depression in adolescents

June 01, 2010

Patients were asked how often in the past two weeks they had experienced a depressed mood and how often they had a lack of pleasure in usual activities.
 

Addition of ECG to pre-participation screening can increase detection of cardiac abnormalities in athletes

June 01, 2010

ECG was also associated with an increase in false positives.
 
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