FLAGYL I.V. INJECTION Rx
Generic Name and Formulations:
Indications for FLAGYL I.V. INJECTION:
Susceptible anaerobic infections. Surgical prophylaxis.
Infuse over 1 hour. Anaerobic infections: 15mg/kg (loading dose), then 7.5mg/kg every 6 hours; max 4g/day. Prophylaxis: see literature.
Pregnancy (1st trimester for trichomoniasis).
CNS disease. Discontinue if neurological symptoms occur. Severe hepatic disease: reduce dose. Candidiasis. History of blood dyscrasias. Monitor leukocytes before and after therapy. Elderly: monitor serum levels. Pregnancy (Cat.B). Nursing mothers: not recommended.
Avoid alcohol during and for 3 days after use. Do not give within 2 weeks of disulfiram (possible psychotic reactions). May potentiate oral anticoagulants, phenytoin, lithium. Antagonized by phenobarbital, phenytoin, other hepatic enzyme inducers. May impair phenytoin clearance. Potentiated by cimetidine, other hepatic enzyme inhibitors. Interferes with serum chemistry tests.
Seizures, peripheral neuropathy, GI upset, anorexia, constipation, headache, metallic taste, ECT changes, dysuria.
Tabs—50, 100; Caps 375mg—50; IV—24