Gastroenterology

Colorectal cancer mortality rates increasing in younger white adults

Colorectal cancer mortality rates increasing in younger white adults

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Researchers analyzed colorectal cancer mortality rates among individuals between 20 and 54 years of age from 1970 through 2014.

Adding oats to a gluten-free diet may not affect patients with celiac disease

Adding oats to a gluten-free diet may not affect patients with celiac disease

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The addition of oats to a gluten-free diet did not affect symptoms, histology, immunity, or serologic features in patients with celiac disease.

Inflammatory bowel disease less likely in children and teens from rural areas

Inflammatory bowel disease less likely in children and teens from rural areas

Environmental risk factors that predispose people to inflammatory bowel disease may have a stronger effect in children than adults.

Financial incentive linked to increased colonoscopy rates

Financial incentive linked to increased colonoscopy rates

Researchers found that a cash incentive of $100 was associated with increased colorectal screening rates in eligible adults.

Adverse events common in hospitalized patients taking antibiotics

Adverse events common in hospitalized patients taking antibiotics

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Many adverse events could be avoidable with more judicious use of antibiotics.

Antibody screenings could detect celiac disease in asymptomatic children

Antibody screenings could detect celiac disease in asymptomatic children

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Serum TG2A screening has a positive predictive value of 61% to detect celiac disease.

Increased adenoma detection rate associated with lower risk of colorectal cancer and death

Increased adenoma detection rate associated with lower risk of colorectal cancer and death

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An increased ADR is associated with an adjusted hazard ratio of 0.63 for interval colorectal cancer and 0.50 for cancer death.

Immune profile differs during symptom flare for patients with irritable bowel syndrome

Immune profile differs during symptom flare for patients with irritable bowel syndrome

Interferon- concentrations and THELPER cells are significantly reduced during symptom flares.

Proton pump inhibitor use associated with excess risk of death

Proton pump inhibitor use associated with excess risk of death

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Risk of death is increased among those without gastrointestinal conditions and with prolonged use.

Risk-scoring model predicts advanced colorectal neoplasia in younger adults

Risk-scoring model predicts advanced colorectal neoplasia in younger adults

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The score could help predict advanced colorectal neoplasia in adults younger than 50 years of age.

Endoscopy's role in primary sclerosing cholangitis: a clinical guideline

Endoscopy's role in primary sclerosing cholangitis: a clinical guideline

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The guideline is intended to be an educational device to provide information that may assist endoscopists in providing care to patients.

Breast milk bacteria seed development of infant gut microbiome

Breast milk bacteria seed development of infant gut microbiome

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Findings show that bacteria from mothers' breast milk and areolar skin are transferred to their infants' guts.

FDA approves medical device to treat esophageal atresia

FDA approves medical device to treat esophageal atresia

The new device uses magnetic catheters to draw the upper and lower esophagus together.

Elemental diet restores esophageal mucosal integrity in eosinophilic esophagitis

Elemental diet restores esophageal mucosal integrity in eosinophilic esophagitis

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However, duodenal integrity appears to not be affected in eosinophilic esophagitis.

Gluten consumption affects symptom onset in functional dyspepsia

Gluten consumption affects symptom onset in functional dyspepsia

Gluten-rich food may lead to symptom onset, specifically early satiety, in patients with functional dyspepsia.

Zinc effective in children with presymptomatic Wilson disease

Zinc effective in children with presymptomatic Wilson disease

Treatment was effective in patients under 6 years who received 50 mg/day of zinc as an initial dose.

Side effects may affect medication nonadherence in patients with chronic disease

Side effects may affect medication nonadherence in patients with chronic disease

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Almost half of participants reported that they never received information regarding the side effects of their medication from their prescriber.

Long-term gluten consumption not linked to coronary heart disease

Long-term gluten consumption not linked to coronary heart disease

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Avoiding gluten may result in reduced consumption of beneficial whole grains that could affect cardiovascular risk.

Colonoscopy timing after positive fecal test linked to colorectal cancer risk

Colonoscopy timing after positive fecal test linked to colorectal cancer risk

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A follow-up colonoscopy more than 10 months after a positive FIT result is associated with a higher risk of colorectal cancer and more advanced disease at the time of diagnosis.

Long-term antibiotic use associated with an increased risk of colorectal adenoma

Long-term antibiotic use associated with an increased risk of colorectal adenoma

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Increasing duration of antibiotic use at ages 20 to 39 and 40 to 59 is significantly associated with an increased risk of colorectal adenoma.

Apixaban linked to lower risk of gastrointestinal bleeding

Apixaban linked to lower risk of gastrointestinal bleeding

Apixaban is associated with a lower risk of gastrointestinal bleeding than rivaroxaban or dabigatran.

An unusual pelvic mass in a 43-year-old woman

An unusual pelvic mass in a 43-year-old woman

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A woman who is in generally good health presents with a visibly enlarged abdomen with left-sided dominance and increased pelvic pressure that had worsened.

Celiac disease linked to diagnosis of anorexia nervosa

Celiac disease linked to diagnosis of anorexia nervosa

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Celiac disease is associated with anorexia nervosa before and after a diagnosis of celiac disease.

FDA approves first direct-to-consumer genetic health risk test

FDA approves first direct-to-consumer genetic health risk test

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The test will provide information on an individual's genetic predisposition to 10 diseases or conditions.

Screening for celiac disease: A USPSTF recommendation statement

Screening for celiac disease: A USPSTF recommendation statement

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The USPSTF evaluated the benefits and harms of screening vs not screening, targeted vs universal screening, and treatment for celiac disease.

Gastric acid suppressants may increase risk of recurrent <i>Clostridium difficile</i> infection

Gastric acid suppressants may increase risk of recurrent Clostridium difficile infection

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A meta-analysis suggests that patients who take gastric acid suppressants may have a higher risk for recurrent CDI.

Predicting high healthcare costs in patients with inflammatory bowel disease

Predicting high healthcare costs in patients with inflammatory bowel disease

Researchers identified 5 factors that identify patients with IBD at high risk for hospitalization, emergency department visits, and high treatment charges in the next year.

Colorectal cancer characteristics different, outcomes worse among octogenarians

Colorectal cancer characteristics different, outcomes worse among octogenarians

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Octogenarians with colorectal cancer have several differences in clinical and tumor characteristics, compared with younger patients with the disease.

Budesonide oral suspension may be effective for eosinophilic esophagitis

Budesonide oral suspension may be effective for eosinophilic esophagitis

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Budesonide oral suspension treatment improved symptomatic, endoscopic, and histologic parameters in eosinophilic esophagitis.

Irritable bowel syndrome medication linked to pancreatitis in certain patients

Irritable bowel syndrome medication linked to pancreatitis in certain patients

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The FDA has received 120 reports of serious cases of pancreatitis or death after the approval of Viberzi in May 2015.

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