Gastroenterology

Colorectal cancer characteristics different, outcomes worse among octogenarians

Colorectal cancer characteristics different, outcomes worse among octogenarians

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Octogenarians with colorectal cancer have several differences in clinical and tumor characteristics, compared with younger patients with the disease.

Budesonide oral suspension may be effective for eosinophilic esophagitis

Budesonide oral suspension may be effective for eosinophilic esophagitis

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Budesonide oral suspension treatment improved symptomatic, endoscopic, and histologic parameters in eosinophilic esophagitis.

Irritable bowel syndrome medication linked to pancreatitis in certain patients

Irritable bowel syndrome medication linked to pancreatitis in certain patients

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The FDA has received 120 reports of serious cases of pancreatitis or death after the approval of Viberzi in May 2015.

Additional weight may affect risk of gastrointestinal cancers

Additional weight may affect risk of gastrointestinal cancers

Excess weight could influence the risk of of gastrointestinal cancers by altering insulin levels and promoting inflammation.

FODMAP diet effective for irritable bowel syndrome

FODMAP diet effective for irritable bowel syndrome

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Implementation of the FODMAP diet is an effective strategy to manage symptoms of IBS, including bloating and abdominal pain.

Gluten challenge not effective for confirming non-celiac gluten sensitivity

Gluten challenge not effective for confirming non-celiac gluten sensitivity

Thirty-eight of 231 NCGS patients showed gluten-specific symptoms when completing the placebo-controlled gluten challenge.

Gluten-free diet may increase risk of type 2 diabetes

Gluten-free diet may increase risk of type 2 diabetes

Individuals who consume the least amount of gluten are more likely to develop type 2 diabetes.

Evaluating abnormal liver chemistries: a clinical guideline

Evaluating abnormal liver chemistries: a clinical guideline

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The American College of Gastroenterology has released recommendations of preferred approaches for diagnosing and evaluating patients with abnormal liver test results.

Proton pump inhibitor use may decrease healthcare visits in GERD patients

Proton pump inhibitor use may decrease healthcare visits in GERD patients

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Among GERD patients, the mean annual ARI episode dropped from 4.39 during the year before PPI treatment to 3.89 after treatment with a PPI.

FDA approves Trulance for chronic idiopathic constipation treatment

FDA approves Trulance for chronic idiopathic constipation treatment

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Trulance has been approved for the treatment of chronic idiopathic constipation in adults.

Endoscopic sleeve gastroplasty results in successful weight loss

Endoscopic sleeve gastroplasty results in successful weight loss

The procedure could be used as alternative to bariatric surgery for selected patients with obesity.

HCV patients with diabetes may have increased risk of hepatocellular carcinoma

HCV patients with diabetes may have increased risk of hepatocellular carcinoma

Diabetes could increase the risk of developing hepatocellular carcinoma in patients with hepatitis C.

Gastrointestinal adverse events increase with GLP-1 receptor agonists

Gastrointestinal adverse events increase with GLP-1 receptor agonists

Risk was dependent on dose, background medications, and type of GLP-1 receptor agonist.

Antibiotics associated with reduced mortality rate in cirrhosis patients

Antibiotics associated with reduced mortality rate in cirrhosis patients

Timely administration of antibiotics was associated with a 30% reduction in 30 day mortality.

Liver hepatotoxicity results from herbal, dietary supplements

Liver hepatotoxicity results from herbal, dietary supplements

The ultimate goal should be to more closely regulate potentially injurious ingredients in herbal and dietary supplements.

FDA requires black box warning on HCV drugs regarding potential HBV reactivation

FDA requires black box warning on HCV drugs regarding potential HBV reactivation

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The FDA issues a warning about the risk of hepatitis B virus reactivation among patients taking direct-acting antivirals to treat hepatitis C infections.

Biologic agents may increase infection risk in inflammatory bowel disease

Biologic agents may increase infection risk in inflammatory bowel disease

Biologic agents increase the risk of opportunistic infection, but do not increase the risk of serious infection or malignancy.

Exercise reduces lipid content in nonalcoholic fatty liver disease

Exercise reduces lipid content in nonalcoholic fatty liver disease

Physical Activity reduces intrahepatic lipid content and markers of hepatocellular injury in patients with NAFLD and this effect correlated with baseline body mass index.

Patients diagnosed with upper functional gastroenterology disorders often have irritable bowel syndrome

Patients diagnosed with upper functional gastroenterology disorders often have irritable bowel syndrome

The risk factors for IBS-FD overlap deserve more concern, according to the authors.

Pancreatic cancer is most lethal pancreatic disorder worldwide

Pancreatic cancer is most lethal pancreatic disorder worldwide

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The mortality rate from pancreatic cancer is significantly higher in the American region than in the European and Western Pacific regions.

Chronic pancreatitis in women typically not related to alcohol use

Chronic pancreatitis in women typically not related to alcohol use

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Most cases of chronic pancreatitis in women are from nonalcoholic etiologies, according to researchers.

USPSTF recommends screening for colorectal cancer from age 50 to 75

USPSTF recommends screening for colorectal cancer from age 50 to 75

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The USPSTF has released a recommendation statement regarding screening adults for colorectal cancer.

A step-by-step approach to managing gastrointestinal bleeding

A step-by-step approach to managing gastrointestinal bleeding

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Using a stepwise approach to diagnose and treat gastrointestinal bleeding can improve patient outcomes.

Keep misconceptions in mind when recommending probiotics

Keep misconceptions in mind when recommending probiotics

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When recommending probiotics to patients, NPs should remember that different strains have different health benefits.

Oral contraceptives increase surgery risk for women with Crohn disease

Oral contraceptives increase surgery risk for women with Crohn disease

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Women with Crohn disease who use oral contraceptives for more than 1 year have an increased risk of surgery.

FDA warns that misuse of antidiarrheal loperamide can cause severe cardiac events

FDA warns that misuse of antidiarrheal loperamide can cause severe cardiac events

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The FDA warns that the antidiarrheal loperamide can lead to serious cardiac events when taken in high doses.

An unusual cause 
of respiratory distress in an infant

An unusual cause 
of respiratory distress in an infant

A congenital condition is found in an infant with respiratory and gastrointestinal symptoms.

Odorous stools, laboratory abnormalities after gastric bypass surgery

Odorous stools, laboratory abnormalities after gastric bypass surgery

A patient comes to her yearly nutrition check-up 11 years after undergoing gastric bypass surgery with reports of loose stools with significant odor several times per day.

Greater gluten intake before age 2 may increase risk of celiac disease

Greater gluten intake before age 2 may increase risk of celiac disease

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High gluten intake during the first 2 years of life was associated with an increased risk of celiac disease during childhood.

Low-dose aspirin regimen may reduce risk of certain cancers

Low-dose aspirin regimen may reduce risk of certain cancers

A low-dose aspirin regimen was associated with a 3% lower risk of cancer overall.

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