Gastroenterology

Metachronous gastric cancer risk reduced with <i>H pylori</i> treatment

Metachronous gastric cancer risk reduced with H pylori treatment

Antibiotic treatment for Helicobacter pylori in patients who underwent endoscopic resection of early-stage gastric cancer or high-grade adenoma is associated with a reduced rate of metachronous gastric cancer.

Inflammatory bowel disease risk associated with DPP-4 inhibitor use

Inflammatory bowel disease risk associated with DPP-4 inhibitor use

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Patients with type 2 diabetes have a greater risk for developing inflammatory bowel disease when using dipeptidyl peptidase-4 inhibitors.

Hip fracture risks increase with short-term PPI use in patients with Alzheimer's disease

Hip fracture risks increase with short-term PPI use in patients with Alzheimer's disease

Short-term proton pump inhibitors (PPIs) are linked to an elevated risk for hip fracture among patients with Alzheimer's disease. No link is seem among patients taking long-term or cumulative PPIs.

High fiber diet beneficial for gut bacteria development in type 2 diabetes

High fiber diet beneficial for gut bacteria development in type 2 diabetes

A high fiber diet promotes gut bacteria that helps blood glucose control in patients with type 2 diabetes.

Appendicitis risk greater one week after colonoscopy

Appendicitis risk greater one week after colonoscopy

Investigators found more frequent appendicitis, appendectomy codes in the first week following colonoscopy than the next 51 weeks.

CDC investigating <i>E. coli</i> outbreak in 13 states

CDC investigating E. coli outbreak in 13 states

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An outbreak of E. coli O157:H7 have been reported in 13 states in the US as well as Canada.

Oral capsule of fecal transplant may be effective for <i>C. difficile</i> infection

Oral capsule of fecal transplant may be effective for C. difficile infection

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Oral capsule FMT and colonoscopy delivery showed similar patient outcomes, low rate differences, and high success rates.

FODMAP vs GDA diets for patients with irritable bowel syndrome

FODMAP vs GDA diets for patients with irritable bowel syndrome

Patients with irritable bowel syndrome found FODMAP more beneficial than general dietary advice

Short-term probiotics linked to lower fat percentage in overweight, obese patients

Short-term probiotics linked to lower fat percentage in overweight, obese patients

The meta-analysis showed that short-term probiotic supplementation reduced body weight, BMI, and fat percentage, but the effect sizes were small.

Dabigatran, rivaroxaban associated with increased risk of major gastrointestinal bleeding

Dabigatran, rivaroxaban associated with increased risk of major gastrointestinal bleeding

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The data suggest possible variability across NOACs regarding gastrointestinal bleeding risk, with an increased risk associated with rivaroxaban and dabigatran.

Gastroesophageal adenocarcinoma patients benefit from adjuvant chemotherapy

Gastroesophageal adenocarcinoma patients benefit from adjuvant chemotherapy

The researchers found that patients receiving adjuvant chemotherapy for gastroesophageal adenocarcinoma were younger, more likely to have advanced disease, and had shorter postoperative inpatient stays.

Physical and psychological coping skills associated with symptom severity in IBS

Physical and psychological coping skills associated with symptom severity in IBS

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The association is partially mediated by levels of anxiety and depressive symptoms.

Colonoscopy rates improve from patient navigators, provider reminders

Colonoscopy rates improve from patient navigators, provider reminders

Patient-level interventions include changes to invitation, giving results or follow-up appointments, and patient navigators, and provider-level interventions include reminders or performance data.

Gastric bypass surgery effective for weight loss, diabetes prevention for 12 years

Gastric bypass surgery effective for weight loss, diabetes prevention for 12 years

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The 12-year results show that Roux-en-Y gastric bypass offered long-term durability of weight loss and was associated with fewer obesity-related coexisting conditions compared with those who did not have the surgery.

Pediatric inflammatory bowel disease increases cancer risk in adulthood

Pediatric inflammatory bowel disease increases cancer risk in adulthood

Patients with childhood-onset IBD have an increased risk of cancer, especially gastrointestinal cancers, lymphoid neoplasms, and skin cancer,

Case Study: Abdominal pain, distention, and constipation

Case Study: Abdominal pain, distention, and constipation

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A 64-year-old man presents to the emergency department with abdominal pain and distention, as well as constipation of 8 days' duration.

Colon cleansing regimens in inflammatory bowel disease: a review

Colon cleansing regimens in inflammatory bowel disease: a review

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A PEG low-volume regimen is similar to a PEG high-volume regimen for colon cleansing in patients with IBS.

GERD may be associated with long-term risk of pneumonia

GERD may be associated with long-term risk of pneumonia

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Incidence of pneumonia was higher among patients with GERD compared with matched controls.

Clinical pathway beneficial for pediatric acute gastroenteritis

Clinical pathway beneficial for pediatric acute gastroenteritis

Clinical pathway to improve care of acute gastroenteritis patients is associated with a sustained reduction in IV fluid use and length of stay in the pediatric emergency department.

Asthma associated with later development of inflammatory bowel disease

Asthma associated with later development of inflammatory bowel disease

Asthma was associated with Crohn's disease and with early- and late-onset ulcerative colitis.

Colorectal cancer mortality rates increasing in younger white adults

Colorectal cancer mortality rates increasing in younger white adults

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Researchers analyzed colorectal cancer mortality rates among individuals between 20 and 54 years of age from 1970 through 2014.

Adding oats to a gluten-free diet may not affect patients with celiac disease

Adding oats to a gluten-free diet may not affect patients with celiac disease

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The addition of oats to a gluten-free diet did not affect symptoms, histology, immunity, or serologic features in patients with celiac disease.

Inflammatory bowel disease less likely in children and teens from rural areas

Inflammatory bowel disease less likely in children and teens from rural areas

Environmental risk factors that predispose people to inflammatory bowel disease may have a stronger effect in children than adults.

Financial incentive linked to increased colonoscopy rates

Financial incentive linked to increased colonoscopy rates

Researchers found that a cash incentive of $100 was associated with increased colorectal screening rates in eligible adults.

Adverse events common in hospitalized patients taking antibiotics

Adverse events common in hospitalized patients taking antibiotics

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Many adverse events could be avoidable with more judicious use of antibiotics.

Antibody screenings could detect celiac disease in asymptomatic children

Antibody screenings could detect celiac disease in asymptomatic children

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Serum TG2A screening has a positive predictive value of 61% to detect celiac disease.

Increased adenoma detection rate associated with lower risk of colorectal cancer and death

Increased adenoma detection rate associated with lower risk of colorectal cancer and death

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An increased ADR is associated with an adjusted hazard ratio of 0.63 for interval colorectal cancer and 0.50 for cancer death.

Immune profile differs during symptom flare for patients with irritable bowel syndrome

Immune profile differs during symptom flare for patients with irritable bowel syndrome

Interferon- concentrations and THELPER cells are significantly reduced during symptom flares.

Proton pump inhibitor use associated with excess risk of death

Proton pump inhibitor use associated with excess risk of death

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Risk of death is increased among those without gastrointestinal conditions and with prolonged use.

Risk-scoring model predicts advanced colorectal neoplasia in younger adults

Risk-scoring model predicts advanced colorectal neoplasia in younger adults

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The score could help predict advanced colorectal neoplasia in adults younger than 50 years of age.

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