Gastroenterology

Gastroesophageal adenocarcinoma patients benefit from adjuvant chemotherapy

Gastroesophageal adenocarcinoma patients benefit from adjuvant chemotherapy

The researchers found that patients receiving adjuvant chemotherapy for gastroesophageal adenocarcinoma were younger, more likely to have advanced disease, and had shorter postoperative inpatient stays.

Physical and psychological coping skills associated with symptom severity in IBS

Physical and psychological coping skills associated with symptom severity in IBS

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The association is partially mediated by levels of anxiety and depressive symptoms.

Colonoscopy rates improve from patient navigators, provider reminders

Colonoscopy rates improve from patient navigators, provider reminders

Patient-level interventions include changes to invitation, giving results or follow-up appointments, and patient navigators, and provider-level interventions include reminders or performance data.

Gastric bypass surgery effective for weight loss, diabetes prevention for 12 years

Gastric bypass surgery effective for weight loss, diabetes prevention for 12 years

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The 12-year results show that Roux-en-Y gastric bypass offered long-term durability of weight loss and was associated with fewer obesity-related coexisting conditions compared with those who did not have the surgery.

Pediatric inflammatory bowel disease increases cancer risk in adulthood

Pediatric inflammatory bowel disease increases cancer risk in adulthood

Patients with childhood-onset IBD have an increased risk of cancer, especially gastrointestinal cancers, lymphoid neoplasms, and skin cancer,

Case Study: Abdominal pain, distention, and constipation

Case Study: Abdominal pain, distention, and constipation

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A 64-year-old man presents to the emergency department with abdominal pain and distention, as well as constipation of 8 days' duration.

Colon cleansing regimens in inflammatory bowel disease: a review

Colon cleansing regimens in inflammatory bowel disease: a review

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A PEG low-volume regimen is similar to a PEG high-volume regimen for colon cleansing in patients with IBS.

GERD may be associated with long-term risk of pneumonia

GERD may be associated with long-term risk of pneumonia

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Incidence of pneumonia was higher among patients with GERD compared with matched controls.

Clinical pathway beneficial for pediatric acute gastroenteritis

Clinical pathway beneficial for pediatric acute gastroenteritis

Clinical pathway to improve care of acute gastroenteritis patients is associated with a sustained reduction in IV fluid use and length of stay in the pediatric emergency department.

Asthma associated with later development of inflammatory bowel disease

Asthma associated with later development of inflammatory bowel disease

Asthma was associated with Crohn's disease and with early- and late-onset ulcerative colitis.

Colorectal cancer mortality rates increasing in younger white adults

Colorectal cancer mortality rates increasing in younger white adults

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Researchers analyzed colorectal cancer mortality rates among individuals between 20 and 54 years of age from 1970 through 2014.

Adding oats to a gluten-free diet may not affect patients with celiac disease

Adding oats to a gluten-free diet may not affect patients with celiac disease

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The addition of oats to a gluten-free diet did not affect symptoms, histology, immunity, or serologic features in patients with celiac disease.

Inflammatory bowel disease less likely in children and teens from rural areas

Inflammatory bowel disease less likely in children and teens from rural areas

Environmental risk factors that predispose people to inflammatory bowel disease may have a stronger effect in children than adults.

Financial incentive linked to increased colonoscopy rates

Financial incentive linked to increased colonoscopy rates

Researchers found that a cash incentive of $100 was associated with increased colorectal screening rates in eligible adults.

Adverse events common in hospitalized patients taking antibiotics

Adverse events common in hospitalized patients taking antibiotics

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Many adverse events could be avoidable with more judicious use of antibiotics.

Antibody screenings could detect celiac disease in asymptomatic children

Antibody screenings could detect celiac disease in asymptomatic children

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Serum TG2A screening has a positive predictive value of 61% to detect celiac disease.

Increased adenoma detection rate associated with lower risk of colorectal cancer and death

Increased adenoma detection rate associated with lower risk of colorectal cancer and death

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An increased ADR is associated with an adjusted hazard ratio of 0.63 for interval colorectal cancer and 0.50 for cancer death.

Immune profile differs during symptom flare for patients with irritable bowel syndrome

Immune profile differs during symptom flare for patients with irritable bowel syndrome

Interferon- concentrations and THELPER cells are significantly reduced during symptom flares.

Proton pump inhibitor use associated with excess risk of death

Proton pump inhibitor use associated with excess risk of death

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Risk of death is increased among those without gastrointestinal conditions and with prolonged use.

Risk-scoring model predicts advanced colorectal neoplasia in younger adults

Risk-scoring model predicts advanced colorectal neoplasia in younger adults

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The score could help predict advanced colorectal neoplasia in adults younger than 50 years of age.

Endoscopy's role in primary sclerosing cholangitis: a clinical guideline

Endoscopy's role in primary sclerosing cholangitis: a clinical guideline

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The guideline is intended to be an educational device to provide information that may assist endoscopists in providing care to patients.

Breast milk bacteria seed development of infant gut microbiome

Breast milk bacteria seed development of infant gut microbiome

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Findings show that bacteria from mothers' breast milk and areolar skin are transferred to their infants' guts.

FDA approves medical device to treat esophageal atresia

FDA approves medical device to treat esophageal atresia

The new device uses magnetic catheters to draw the upper and lower esophagus together.

Elemental diet restores esophageal mucosal integrity in eosinophilic esophagitis

Elemental diet restores esophageal mucosal integrity in eosinophilic esophagitis

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However, duodenal integrity appears to not be affected in eosinophilic esophagitis.

Gluten consumption affects symptom onset in functional dyspepsia

Gluten consumption affects symptom onset in functional dyspepsia

Gluten-rich food may lead to symptom onset, specifically early satiety, in patients with functional dyspepsia.

Zinc effective in children with presymptomatic Wilson disease

Zinc effective in children with presymptomatic Wilson disease

Treatment was effective in patients under 6 years who received 50 mg/day of zinc as an initial dose.

Side effects may affect medication nonadherence in patients with chronic disease

Side effects may affect medication nonadherence in patients with chronic disease

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Almost half of participants reported that they never received information regarding the side effects of their medication from their prescriber.

Long-term gluten consumption not linked to coronary heart disease

Long-term gluten consumption not linked to coronary heart disease

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Avoiding gluten may result in reduced consumption of beneficial whole grains that could affect cardiovascular risk.

Colonoscopy timing after positive fecal test linked to colorectal cancer risk

Colonoscopy timing after positive fecal test linked to colorectal cancer risk

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A follow-up colonoscopy more than 10 months after a positive FIT result is associated with a higher risk of colorectal cancer and more advanced disease at the time of diagnosis.

Long-term antibiotic use associated with an increased risk of colorectal adenoma

Long-term antibiotic use associated with an increased risk of colorectal adenoma

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Increasing duration of antibiotic use at ages 20 to 39 and 40 to 59 is significantly associated with an increased risk of colorectal adenoma.

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