Gastroenterology

Gastrointestinal adverse events increase with GLP-1 receptor agonists

Gastrointestinal adverse events increase with GLP-1 receptor agonists

Risk was dependent on dose, background medications, and type of GLP-1 receptor agonist.

Antibiotics associated with reduced mortality rate in cirrhosis patients

Antibiotics associated with reduced mortality rate in cirrhosis patients

Timely administration of antibiotics was associated with a 30% reduction in 30 day mortality.

Liver hepatotoxicity results from herbal, dietary supplements

Liver hepatotoxicity results from herbal, dietary supplements

The ultimate goal should be to more closely regulate potentially injurious ingredients in herbal and dietary supplements.

FDA requires black box warning on HCV drugs regarding potential HBV reactivation

FDA requires black box warning on HCV drugs regarding potential HBV reactivation

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The FDA issues a warning about the risk of hepatitis B virus reactivation among patients taking direct-acting antivirals to treat hepatitis C infections.

Biologic agents may increase infection risk in inflammatory bowel disease

Biologic agents may increase infection risk in inflammatory bowel disease

Biologic agents increase the risk of opportunistic infection, but do not increase the risk of serious infection or malignancy.

Exercise reduces lipid content in nonalcoholic fatty liver disease

Exercise reduces lipid content in nonalcoholic fatty liver disease

Physical Activity reduces intrahepatic lipid content and markers of hepatocellular injury in patients with NAFLD and this effect correlated with baseline body mass index.

Patients diagnosed with upper functional gastroenterology disorders often have irritable bowel syndrome

Patients diagnosed with upper functional gastroenterology disorders often have irritable bowel syndrome

The risk factors for IBS-FD overlap deserve more concern, according to the authors.

Pancreatic cancer is most lethal pancreatic disorder worldwide

Pancreatic cancer is most lethal pancreatic disorder worldwide

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The mortality rate from pancreatic cancer is significantly higher in the American region than in the European and Western Pacific regions.

Chronic pancreatitis in women typically not related to alcohol use

Chronic pancreatitis in women typically not related to alcohol use

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Most cases of chronic pancreatitis in women are from nonalcoholic etiologies, according to researchers.

USPSTF recommends screening for colorectal cancer from age 50 to 75

USPSTF recommends screening for colorectal cancer from age 50 to 75

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The USPSTF has released a recommendation statement regarding screening adults for colorectal cancer.

A step-by-step approach to managing gastrointestinal bleeding

A step-by-step approach to managing gastrointestinal bleeding

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Using a stepwise approach to diagnose and treat gastrointestinal bleeding can improve patient outcomes.

Keep misconceptions in mind when recommending probiotics

Keep misconceptions in mind when recommending probiotics

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When recommending probiotics to patients, NPs should remember that different strains have different health benefits.

Oral contraceptives increase surgery risk for women with Crohn disease

Oral contraceptives increase surgery risk for women with Crohn disease

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Women with Crohn disease who use oral contraceptives for more than 1 year have an increased risk of surgery.

FDA warns that misuse of antidiarrheal loperamide can cause severe cardiac events

FDA warns that misuse of antidiarrheal loperamide can cause severe cardiac events

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The FDA warns that the antidiarrheal loperamide can lead to serious cardiac events when taken in high doses.

An unusual cause 
of respiratory distress in an infant

An unusual cause 
of respiratory distress in an infant

A congenital condition is found in an infant with respiratory and gastrointestinal symptoms.

Odorous stools, laboratory abnormalities after gastric bypass surgery

Odorous stools, laboratory abnormalities after gastric bypass surgery

A patient comes to her yearly nutrition check-up 11 years after undergoing gastric bypass surgery with reports of loose stools with significant odor several times per day.

Greater gluten intake before age 2 may increase risk of celiac disease

Greater gluten intake before age 2 may increase risk of celiac disease

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High gluten intake during the first 2 years of life was associated with an increased risk of celiac disease during childhood.

Low-dose aspirin regimen may reduce risk of certain cancers

Low-dose aspirin regimen may reduce risk of certain cancers

A low-dose aspirin regimen was associated with a 3% lower risk of cancer overall.

Benefit of fiber intake not equal in IBD patients

Benefit of fiber intake not equal in IBD patients

Patients with Crohn disease who ate high-fiber foods were 40% less likely to have a disease flare.

Crohn disease: diagnosis and treatment

Crohn disease: diagnosis and treatment

A condition prone to recurrence, Crohn disease has a complicated presentation and pathophysiology, but multiple treatment options are available.

Constipation: Diagnosis and treatment overview

Constipation: Diagnosis and treatment overview

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Strong evidence for efficacy has been established for stimulant and osmotic laxatives, new intestinal secretagogues, and peripherally restricted μ-opiate receptor antagonists, according to a review in JAMA.

Probiotics in clinical practice

Probiotics in clinical practice

Probiotics may be beneficial for antibiotic-associated diarrhea, digestive symptoms, necrotizing enterocolitis, respiratory tract infections, and other health conditions.

OTC and herbal 
treatment of upper
 and lower GI problems

OTC and herbal 
treatment of upper
 and lower GI problems

A wide array of OTC and herbal products can help treat patients with GI issues.

Soothing coughs and sore throats with marshmallow

Soothing coughs and sore throats with marshmallow

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The leaves and roots of the marshmallow plant can be used as an antitussive and for sore throat relief.

PAMORA for opioid-induced constipation

PAMORA for opioid-induced constipation

Naloxegol functions as a peripherally acting mu-opioid receptor antagonist in tissues such as the gastrointestinal tract, thereby decreasing the constipating effects of opioids.

Delphi methods can improve gastroenterology, liver workups

Delphi methods can improve gastroenterology, liver workups

Delphi methodology can optimize gastroenterology and hepatology workups.

Colonoscopy prep is more effective with split-dose regimen

Colonoscopy prep is more effective with split-dose regimen

The quality of colon cleansing is better with split-dose regimens than with day-before prep.

Antibiotics may be alternative 
to appendectomy in some patients

Antibiotics may be alternative 
to appendectomy in some patients

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Patients with uncomplicated appendicitis may be treated with antibiotics instead of surgery.

PPIs linked to heart attack

PPIs linked to heart attack

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Adults who took PPIs had a significantly higher risk of heart attack compared with those who didn't.

Gastritis tied to metformin-related gastrointestinal side effects in type 2 diabetes

Gastritis tied to metformin-related gastrointestinal side effects in type 2 diabetes

With metformin, mean score for gastrointestinal side effects higher for gastritis subjects over four weeks.

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