Gastroesophageal Reflux Disease (GERD)
Among GERD patients, the mean annual ARI episode dropped from 4.39 during the year before PPI treatment to 3.89 after treatment with a PPI.
Regular proton pump inhibitor use in the elderly was associated with an increased risk of incident dementia compared with no proton pump inhibitor use, according to researchers.
Both prescription and OTC proton pump inhibitors have been linked to an increased risk for development of dementia.
Adults who took PPIs had a significantly higher risk of heart attack compared with those who didn't.
Increased levels of anxiety correlated with more severe retrosternal pain and burning among patients with gastroesophageal reflux disease (GERD).
Increase in proportion of PPIs discontinued at hospital discharge after intervention implementation.
The FDA has approved esomeprazole magnesium delayed-release capsules, the first generic version of AstraZeneca's Nexium.
A recent study suggested that GERD may influence sleeping patterns.
FDA approves first generic versions of Aciphex delayed-release tablets to treat gastroesophageal reflux disease.
Lansoprazole was associated with higher rates of upper respiratory infection, sore throat and bronchitis and no effect on asthma control.
Most often caused by use of nonsteroidal anti-inflammatory drugs or bacterial infection, peptic ulcer disease usually presents as epigastric pain.
Exercise and weight loss viable treatment options in patients with gastroesophageal reflux disease.
Consider unusual causes of chronic or recurrent ear pain.
Inappropriate endoscopy use generates unnecessary costs and exposes patients to harms without improving outcomes.
The LINX Reflux Management System has been approved to treat people with GERD who continue to have chronic symptoms, despite taking maximum medication and making recommended lifestyle changes.
When choosing among the available treatment options, consideration must be given to local prevalence and antibiotic resistance.
Advise patients who experience watery stool that does not go away, abdominal pain and fever while taking PPIs to seek medical attention immediately.
Patients with functional dyspepsia reaped significant benefits from Helicobacter pylori eradication.
What treatment options are available for chronic esophageal reflux? Is surgery ever preferable to long-term treatment with a proton-pump inhibitor?
What is the likelihood of acid-reflux rebound in a patient stopping a proton-pump inhibitor (PPI) (pantoprazole [Protonix]) after taking the medication for one month or more?
Medically treated patients with mild or absent GERD symptoms were shown to have significantly higher odds of developing Barret's esophagus and esophageal adenocarcinoma.
Can patients be weaned from proton pump inhibitors without causing a reflux flare?
What are the consequences of taking proton pump inhibitors (PPIs) over an extended period of time?
Magnitude of proton pump inhibitor therapy unlikely to be of meaningful clinical significance.
The FDA has determined that osteoporosis and fracture warnings are not needed on the labels of OTC proton pump inhibitors, which are widely used to combat gastroesophageal reflux disease.
Is sertraline effective as an off-label treatment for irritable bowel syndrome?
What first appeared to be infectious esophagitis ended up being a lifelong diagnosis for a young woman.
Respiratory problems lead to neurologic damage for the child and financial ruin for the family.
Due to the risk of more frequent lower respiratory tract infections associated with lansoprazole, some use a histamine-2 blocker first.
PPI users face a potential rise in the risks of fractures and bacterial infection.