Complete genome sequences were elucidated for 31 fetuses from amniotic fluid. Two methods of DNA extraction proved to be relatively equal in quality of complete genome sequence.
The disease allele may be passed from affected grandmother to granddaughter through the father's inherited genes.
Understanding genetic testing allows providers to make the most of this resource in patient care.
The test will provide information on an individual's genetic predisposition to 10 diseases or conditions.
Published practice bulletins offer guidance to clinicians on patient education during pregnancy.
Primary care clinicians should be proficient at assessing the potential for hereditary breast cancer risk in their patients.
Women who receive genetic counseling prior to undergoing BRCA testing display more knowledge of both the testing process and of the potential results.
For hereditary breast, ovarian cancer, multigene testing can influence clinical treatment options.
The activity of a gene called vanin-1 (VNN1) affected whether they were good or poor responders to corticosteroid treatment.
In the absence of Mbd2, dendritic cells display reduced phenotypic activation and a markedly impaired capacity to initiate immunity against helminthes or allergens.
There is a relative 13.5% increase in coronary artery disease risk for every 2.5 inches shaved off a person's height.
The Food and Drug Administration (FDA) has granted marketing of the EnLite Neonatal TREC Kit, the first FDA-cleared test to screen for severe combined immunodeficiency (SCID) in newborns.
Primary-care providers should offer educational materials and genetic counseling to families of newborns with positive results for sickle cell trait.
Gene variants linked to vitamin levels didn't affect cardiovascular-related mortality.
Exercise does not provide its usual benefit against diabetes in patients with high genetic risk for developing type 2 diabetes and insulin resistance.
The test identified whether all patients in the study had either dermatologic condition correctly.
Patients with the rs1229984 gene variant tended to drink less and had healthier hearts.
AP1S3 variants were present in a significant number of patients with acrodermatitis continua of Hallopeau.
The p.E508K mutation, found only in Hispanic patients, is associated with increased prevalence of type 2 diabetes.
Consumers becoming more involved in do-it-yourself genetic testing need primary-care clinicians to put the results into context for them.
Researchers are beginning to unravel the functional significance of key gene variants in psoriasis.
DNA changes on the IFNL3 gene have been associated with better treatment responses and natural ability to clear infection among patients with hepatitis C infection.
Individuals with a greater genetic predisposition to adiposity may be more susceptible to adverse outcomes from fried food consumption.
Genetics may influence how infants respond to food and subsequent obesity risk.
A variant of a gene associated with glutamic acid metabolism increases heart disease risk in patients with diabetes.
Genes may contribute 38% to 53% of the risk of developing those disorders, researchers estimate.
Having a first-degree relative with schizophrenia or bipolar disorder increases risk for autism spectrum disorders.
A patient whose brother or sister has had a stroke could be up to 94% more likely to suffer the same fate than a person with stroke-free siblings.
Is it a good thing or a bad thing when laypeople are able to order their own genetic profiles and interpret their own results?
Exome sequencing used to describe "de novo" genetic mutations and their role in ASD risk reveal that few mutations occur in the same genes and few participants experienced the same changes.