Hematology

Assessing and treating disorders of primary hemostasis

Assessing and treating disorders of primary hemostasis

An evaluation begins with a focused history and physical examination, CBC count with platelet trend, and examination of the peripheral smear.

Warfarin associated with lower cancer risk in older adults

Warfarin associated with lower cancer risk in older adults

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Warfarin use may provide cancer protection across a broad range of malignant neoplasms.

No evidence that the influenza vaccine causes VTE

No evidence that the influenza vaccine causes VTE

In the 1 to 10 days after flu vaccine administration, there was no increased risk for VTE.

Non-vitamin K oral anticoagulants with other medications increase bleeding risk in A-Fib

Non-vitamin K oral anticoagulants with other medications increase bleeding risk in A-Fib

The researchers found that concurrent use of amiodarone, fluconazole, rifampin, and phenytoin was associated with increased risk of major bleeding compared with the use of NOACs alone.

Increased cancer risk found in rheumatoid arthritis patients with VTE

Increased cancer risk found in rheumatoid arthritis patients with VTE

VTE and cancer are the result of inflammation and immunological dysfunctions associated with RA.

Diagnosing a pulmonary embolism and saving a life

Diagnosing a pulmonary embolism and saving a life

A Divine guidance helps a nurse practitioner make a diagnosis that saved a patient's life.

Birth control leads to a blood clot

Birth control leads to a blood clot

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A patient presents with chest pain 6 weeks after beginning use of a contraceptive device.

Antiemetics: a clinical practice guideline update from ASCO

Antiemetics: a clinical practice guideline update from ASCO

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The updated guidelines will help clinicians prevent and manage nausea and vomiting caused by antineoplastic agents or radiation therapy in cancer patients.

Effects of the obesity paradox: VTE risk in atrial fibrillation

Effects of the obesity paradox: VTE risk in atrial fibrillation

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Researchers found a paradoxical increase in thromboembolism risk in low-weight patients with atrial fibrillation and VTE who were treated with direct oral anticoagulants.

Hepatitis B vaccine reduces risk of non-Hodgkin lymphoma in adolescents

Hepatitis B vaccine reduces risk of non-Hodgkin lymphoma in adolescents

The universal vaccination against hepatitis B virus infection prevented non-Hodgkin lymphoma in adolescents.

Restarting anticoagulation may be cost-effective in some VTE cases

Restarting anticoagulation may be cost-effective in some VTE cases

The therapy may be cost-effective for patients with a predicted 1-year VTE risk of 17.5% or more.

Most coagulation tests can be evaluated up to 8 hours after blood collection

Most coagulation tests can be evaluated up to 8 hours after blood collection

Most routine coagulation tests can be reliably assessed in tubes stored for up to 8 hours.

Warfarin dosing in HIV patients with deep venous thrombosis

Warfarin dosing in HIV patients with deep venous thrombosis

Results showed that mean induction times, analyzed in 170 patients, were 12.87 days in the HIV-infected patients and 11.19 days in the HIV-uninfected patients.

Case study: Recurrent deep vein thrombosis in thoracic outlet syndrome

Case study: Recurrent deep vein thrombosis in thoracic outlet syndrome

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A 53-year-old woman presents to the emergency room for right upper extremity deep vein thrombosis after rib resection and subclavian vein stent placement.

Thoracic outlet syndrome: A review

Thoracic outlet syndrome: A review

The condition has one fundamental pathophysiology but multiple distinct clinical presentations, including venous and neurogenic.

Stem cell therapy may be effective for multiple sclerosis

Stem cell therapy may be effective for multiple sclerosis

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Younger age, relapsing forms of MS, fewer prior immunotherapy treatments, and lower baseline EDSS score were factors associated with better outcomes for stem cell transplantation.

Apixaban linked to higher rates of stroke than warfarin in patients with atrial fibrillation

Apixaban linked to higher rates of stroke than warfarin in patients with atrial fibrillation

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Rivaroxaban once daily and dabigatran twice daily showed evidence of lower thromboembolic rates.

New clinical practice guidelines for red blood cell transfusion

New clinical practice guidelines for red blood cell transfusion

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The AABB evaluated studies that examined hemoglobin thresholds for red blood cell transfusion and red blood cell storage duration.

Using activity trackers to monitor transfusion-dependent patients

Using activity trackers to monitor transfusion-dependent patients

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Activity trackers may help transfusion-dependent patients estimate hemoglobin levels.

Globally, public awareness of thrombosis is low

Globally, public awareness of thrombosis is low

People across the world are relatively unaware of thrombosis, especially venous thromboembolism.

Obese patients taking warfarin may have higher bleeding risk

Obese patients taking warfarin may have higher bleeding risk

The heavier someone was, the greater their risk of bleeding while taking warfarin.

Skin lesion leads to diagnosis
 of cutaneous T-cell lymphoma

Skin lesion leads to diagnosis
 of cutaneous T-cell lymphoma

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In diagnosing mycosis fungoides, biopsy is mandatory.

Extending duration of dual antiplatelet therapy in patients with drug-eluting stents yields mixed results

Extending duration of dual antiplatelet therapy in patients with drug-eluting stents yields mixed results

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Extending the duration of DAPT may decrease the risk of stent thrombosis, but evidence on the efficacy of DAPT for greater than one year has been inconsistent.

Novel anticoagulant Savaysa gets FDA nod

Novel anticoagulant Savaysa gets FDA nod

Savaysa (edoxaban) is indicated to treat deep vein thrombosis and pulmonary embolism and prevent stroke.

What to know about home genetic-test kits

What to know about home genetic-test kits

Consumers becoming more involved in do-it-yourself genetic testing need primary-care clinicians to put the results into context for them.

NSAID, anticoagulant tx ups VTE bleeding risk

NSAID, anticoagulant tx ups VTE bleeding risk

Concomitant treatment increases clinically relevant, major bleeding events in patients with venous thromboembolism.

Infant immunization after a 
blood transfusion


Infant immunization after a 
blood transfusion


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Do blood transfusions affect implementation of the routine immunization schedule?

Blood transfusions adversely affect PCI outcomes

Blood transfusions adversely affect PCI outcomes

Transfusion receipt linked to adverse cardiovascular events, regardless of bleeding complications.

Anemia may raise stroke risk for some

Anemia may raise stroke risk for some

Iron deficiency may increase ischemic stroke risk in patients with defective pulmonary capillary filtration.

Do antipsychotics increase the risk of pulmonary embolism?

Do antipsychotics increase the risk of pulmonary embolism?

Is there any evidence that psychiatric medications contribute to a greater risk of pulmonary emboli?

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