Hepatology

Metastatic pancreatic cancer: a new clinical practice guideline

Metastatic pancreatic cancer: a new clinical practice guideline

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The guideline will help clinicians determine the appropriate treatment of patients with metastatic pancreatic cancer.

NASEM report aims to eliminate hepatitis B and C by 2030

NASEM report aims to eliminate hepatitis B and C by 2030

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Aggressive testing, diagnosis, treatment, and prevention methods, such as needle exchange for those who inject drugs, are some of the options that the NASEM explored to target hepatitis elimination.

FDA approves first direct-acting antivirals for pediatric HCV patients

FDA approves first direct-acting antivirals for pediatric HCV patients

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Harvoni and Sovaldi have been approved for pediatric patients with HCV genotypes.

Oral, direct-acting antivirals effective for hepatitis C virus infection

Oral, direct-acting antivirals effective for hepatitis C virus infection

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Regimens for the treatment of hepatitis C that included ribavirin had more mild or moderate adverse events than those without.

Pharmacists can help optimize care in patients with hepatitis C virus

Pharmacists can help optimize care in patients with hepatitis C virus

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Drug-drug interactions are common in patients taking hepatitis C virus medications, and consulting with a pharmacist can be beneficial.

High BMI in late adolescence associated with increased risk of severe liver disease in men

High BMI in late adolescence associated with increased risk of severe liver disease in men

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A high BMI is associated with an increased risk for severe liver disease, and the risk is higher in those who also have type 2 diabetes mellitus.

FODMAP diet effective for irritable bowel syndrome

FODMAP diet effective for irritable bowel syndrome

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Implementation of the FODMAP diet is an effective strategy to manage symptoms of IBS, including bloating and abdominal pain.

Gluten challenge not effective for confirming non-celiac gluten sensitivity

Gluten challenge not effective for confirming non-celiac gluten sensitivity

Thirty-eight of 231 NCGS patients showed gluten-specific symptoms when completing the placebo-controlled gluten challenge.

Evaluating abnormal liver chemistries: a clinical guideline

Evaluating abnormal liver chemistries: a clinical guideline

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The American College of Gastroenterology has released recommendations of preferred approaches for diagnosing and evaluating patients with abnormal liver test results.

Acute pancreatitis may reveal pancreatic cancer at earlier stage

Acute pancreatitis may reveal pancreatic cancer at earlier stage

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Surgical intervention after 24.5 days of acute pancreatitis may be beneficial for reducing postoperative complications.

Personalized treatment for very early stage hepatocellular carcinoma

Personalized treatment for very early stage hepatocellular carcinoma

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Investigators have proposed an algorithm to facilitate the decision-making process of clinical care for patients with very early hepatocellular carcinoma.

Hepatitis C infection linked to nonhepatic cancers among elderly patients

Hepatitis C infection linked to nonhepatic cancers among elderly patients

HCV infection is associated with cancers such as bile duct and pancreatic cancers and diffuse large B-cell lymphoma.

Uric acid concentration and fructose intake linked to NASH in children

Uric acid concentration and fructose intake linked to NASH in children

Serum uric acid concentrations and fructose consumption are associated with non-alcoholic steatohepatitis in children with non-alcoholic fatty liver disease.

Endoscopic sleeve gastroplasty results in successful weight loss

Endoscopic sleeve gastroplasty results in successful weight loss

The procedure could be used as alternative to bariatric surgery for selected patients with obesity.

HCV patients with diabetes may have increased risk of hepatocellular carcinoma

HCV patients with diabetes may have increased risk of hepatocellular carcinoma

Diabetes could increase the risk of developing hepatocellular carcinoma in patients with hepatitis C.

VA offers hepatitis, HIV screening to veterans who received improper dental care

VA offers hepatitis, HIV screening to veterans who received improper dental care

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A VA center in Wisconsin is advising veterans to be screened for hepatitis and HIV after receiving care from a dentist who did not follow VA procedures.

Novel method identifies patients with nonalcoholic fatty liver disease

Novel method identifies patients with nonalcoholic fatty liver disease

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Researchers described a new method to quantify hepatic fibrogenesis flux rates in the liver tissue and noninvasively in blood.

Ledipasvir-sofosbuvir treatment safe for kidney recipients with hepatitis C

Ledipasvir-sofosbuvir treatment safe for kidney recipients with hepatitis C

Treatment for 12 or 24 weeks is safe and efficacious for kidney transplant recipients with hepatitis C virus.

Probable interaction identified between hepatitis C treatments

Probable interaction identified between hepatitis C treatments

Researchers identified an interaction between ribavirin with paritaprevir/ritonavir/ombitasvir and dasabuvir.

More than 1 million people treated with new hepatitis C drugs

More than 1 million people treated with new hepatitis C drugs

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The cost of the new hepatitis C drugs in low- and certain middle-income countries is rapidly declining, according to a WHO study.

Excessive energy drink consumption leads to acute hepatitis case

Excessive energy drink consumption leads to acute hepatitis case

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A 50-year-old man presents to the emergency department with abdominal pain, nausea, jaundice, and dark urine.

Antibiotics associated with reduced mortality rate in cirrhosis patients

Antibiotics associated with reduced mortality rate in cirrhosis patients

Timely administration of antibiotics was associated with a 30% reduction in 30 day mortality.

Liver hepatotoxicity results from herbal, dietary supplements

Liver hepatotoxicity results from herbal, dietary supplements

The ultimate goal should be to more closely regulate potentially injurious ingredients in herbal and dietary supplements.

FDA requires black box warning on HCV drugs regarding potential HBV reactivation

FDA requires black box warning on HCV drugs regarding potential HBV reactivation

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The FDA issues a warning about the risk of hepatitis B virus reactivation among patients taking direct-acting antivirals to treat hepatitis C infections.

Treating alcohol use disorders in patients with alcoholic liver disease

Treating alcohol use disorders in patients with alcoholic liver disease

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Total alcohol abstinence is the cornerstone of treatment for patients with alcohol use disorders and alcoholic liver disease.

Reducing the duration of hepatitis C therapy may be effective

Reducing the duration of hepatitis C therapy may be effective

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Shortening the duration of HCV therapy from 12 weeks to 3 weeks could substantially reduce the cost of treatment.

Exercise reduces lipid content in nonalcoholic fatty liver disease

Exercise reduces lipid content in nonalcoholic fatty liver disease

Physical Activity reduces intrahepatic lipid content and markers of hepatocellular injury in patients with NAFLD and this effect correlated with baseline body mass index.

Patients with hepatitis C prefer therapy with sofosbuvir and ribavirin

Patients with hepatitis C prefer therapy with sofosbuvir and ribavirin

In patients with Hepatitis C, Oral treatment with sofosbuvir plus ribavirin is preferred over interferon based triple therapy.

Pancreatic cancer is most lethal pancreatic disorder worldwide

Pancreatic cancer is most lethal pancreatic disorder worldwide

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The mortality rate from pancreatic cancer is significantly higher in the American region than in the European and Western Pacific regions.

Hepatitis C virus core antigen testing is a highly accurate diagnostic tool

Hepatitis C virus core antigen testing is a highly accurate diagnostic tool

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HCVcAg assays with signal amplification have the potential to replace NAT in settings with high HCV prevalence.

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