Hepatology

Ledipasvir-sofosbuvir treatment safe for kidney recipients with hepatitis C

Ledipasvir-sofosbuvir treatment safe for kidney recipients with hepatitis C

Treatment for 12 or 24 weeks is safe and efficacious for kidney transplant recipients with hepatitis C virus.

More than 1 million people treated with new hepatitis C drugs

More than 1 million people treated with new hepatitis C drugs

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The cost of the new hepatitis C drugs in low- and certain middle-income countries is rapidly declining, according to a WHO study.

Excessive energy drink consumption leads to acute hepatitis case

Excessive energy drink consumption leads to acute hepatitis case

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A 50-year-old man presents to the emergency department with abdominal pain, nausea, jaundice, and dark urine.

Antibiotics associated with reduced mortality rate in cirrhosis patients

Antibiotics associated with reduced mortality rate in cirrhosis patients

Timely administration of antibiotics was associated with a 30% reduction in 30 day mortality.

Liver hepatotoxicity results from herbal, dietary supplements

Liver hepatotoxicity results from herbal, dietary supplements

The ultimate goal should be to more closely regulate potentially injurious ingredients in herbal and dietary supplements.

FDA requires black box warning on HCV drugs regarding potential HBV reactivation

FDA requires black box warning on HCV drugs regarding potential HBV reactivation

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The FDA issues a warning about the risk of hepatitis B virus reactivation among patients taking direct-acting antivirals to treat hepatitis C infections.

Treating alcohol use disorders in patients with alcoholic liver disease

Treating alcohol use disorders in patients with alcoholic liver disease

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Total alcohol abstinence is the cornerstone of treatment for patients with alcohol use disorders and alcoholic liver disease.

Reducing the duration of hepatitis C therapy may be effective

Reducing the duration of hepatitis C therapy may be effective

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Shortening the duration of HCV therapy from 12 weeks to 3 weeks could substantially reduce the cost of treatment.

Exercise reduces lipid content in nonalcoholic fatty liver disease

Exercise reduces lipid content in nonalcoholic fatty liver disease

Physical Activity reduces intrahepatic lipid content and markers of hepatocellular injury in patients with NAFLD and this effect correlated with baseline body mass index.

Patients with hepatitis C prefer therapy with sofosbuvir and ribavirin

Patients with hepatitis C prefer therapy with sofosbuvir and ribavirin

In patients with Hepatitis C, Oral treatment with sofosbuvir plus ribavirin is preferred over interferon based triple therapy.

Pancreatic cancer is most lethal pancreatic disorder worldwide

Pancreatic cancer is most lethal pancreatic disorder worldwide

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The mortality rate from pancreatic cancer is significantly higher in the American region than in the European and Western Pacific regions.

Hepatitis C virus core antigen testing is a highly accurate diagnostic tool

Hepatitis C virus core antigen testing is a highly accurate diagnostic tool

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HCVcAg assays with signal amplification have the potential to replace NAT in settings with high HCV prevalence.

Obeticholic acid may be effective for primary biliary cholangitis

Obeticholic acid may be effective for primary biliary cholangitis

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In patients with primary biliary cholangitis obeticholic acid was associated with significant decreases in alkaline phosphatase and total bilirubin levels.

New hepatology rotation increases knowledge of liver disease among residents

New hepatology rotation increases knowledge of liver disease among residents

A new hepatology rotation increased the mean comfort level for managing several liver diseases.

MRI may be useful in assessing hypovascular hepatic lesions

MRI may be useful in assessing hypovascular hepatic lesions

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Researchers found significant differences on MRI between malignant and benign hypovascular lesions of the liver.

Chronic pancreatitis in women typically not related to alcohol use

Chronic pancreatitis in women typically not related to alcohol use

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Most cases of chronic pancreatitis in women are from nonalcoholic etiologies, according to researchers.

A case of G6PD deficiency

A case of G6PD deficiency

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Patients with G6PD should avoid triggers of oxidative stress.

Shared drug paraphernalia linked to hep C transmission

Shared drug paraphernalia linked to hep C transmission

In a study, 24% of confiscated drug snorting straws tested positive for human blood.

Direct-acting antivirals in hepatitis C do not reduce hepatocellular carcinoma occurrence

Direct-acting antivirals in hepatitis C do not reduce hepatocellular carcinoma occurrence

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Patients previously treated for HCC have a high risk of tumor recurrence in the long term.

Conservative management of gallbladder disease before bariatric surgery is safe

Conservative management of gallbladder disease before bariatric surgery is safe

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At 12 months, 21.2% of patients had developed de novo gallbladder disease.

HIV viral load linked to liver fibrosis

HIV viral load linked to liver fibrosis

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Patients with HIV infection and elevated viral load are likely to progress to advanced hepatic fibrosis.

Epclusa approved to treat chronic hepatitis C

Epclusa approved to treat chronic hepatitis C

The combination drug treats 6 strains of chronic hepatitis C.

Obesity in male adolescents linked to cirrhosis risk

Obesity in male adolescents linked to cirrhosis risk

Older teen adolescents who are overweight are at an increased risk of developing liver cirrhosis later in life.

ASCO releases clinical practice guideline for pancreatic cancer

ASCO releases clinical practice guideline for pancreatic cancer

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A clinical practice guideline offers recommendations on the best course of treatment for patients with potentially treatable pancreatic cancer.

Multidisciplinary approach improves outcomes in hepatitis C

Multidisciplinary approach improves outcomes in hepatitis C

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Patients with hepatitis C who had a multidisciplinary team during treatment had improved outcomes.

Additional treatment not effective to treat pancreatic cancer

Additional treatment not effective to treat pancreatic cancer

Median overall survival was 11.9 months in patients receiving gemcitabine plus erlotinib.

FDA approves Ocaliva to treat primary biliary cholangitis

FDA approves Ocaliva to treat primary biliary cholangitis

The FDA has approved Ocaliva to treat patients with primary biliary cholangitis who have not responded or are intolerant to ursodeoxycholic acid.

Liver transplant readmissions reduced through outpatient services protocol

Liver transplant readmissions reduced through outpatient services protocol

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Patients who underwent orthotopic liver transplants were less likely to be readmitted to the hospital when treated via a specialized protocol.

Tumor recurrence is common in patients with hepatitis C, hepatocellular carcinoma

Tumor recurrence is common in patients with hepatitis C, hepatocellular carcinoma

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Direct-acting antivirals pose challenges in patients with hepatitis C and prior hepatocellular carcinoma

Liver grafts from first-degree relatives do not increase recurrence risk

Liver grafts from first-degree relatives do not increase recurrence risk

The source of a patient's liver transplant did not significantly affect rates of disease recurrence.

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