Hepatology

FDA approves Opdivo for treatment of hepatocellular carcinoma

FDA approves Opdivo for treatment of hepatocellular carcinoma

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The FDA has approved Opdivo (nivolumab) injection for the treatment of patients with HCC who have been previously treated with sorafenib.

Combating the hepatitis A outbreak in San Diego

Combating the hepatitis A outbreak in San Diego

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The 3-part plan to halt the outbreak of hepatitis A focuses on immunization, sanitation and education with most of the efforts focused on the homeless population who are the most at-risk population.

Hepatocellular carcinoma risk unclear after hepatitis C treatment

Hepatocellular carcinoma risk unclear after hepatitis C treatment

The results show no evidence to support a hypothesis of differential impact of interferon and direct-acting antiviral-based cure on risk for HCC occurrence and recurrence.

Pediatric inflammatory bowel disease increases cancer risk in adulthood

Pediatric inflammatory bowel disease increases cancer risk in adulthood

Patients with childhood-onset IBD have an increased risk of cancer, especially gastrointestinal cancers, lymphoid neoplasms, and skin cancer,

Coffee consumption associated with reduced liver cancer risk, no link to biliary tract cancer

Coffee consumption associated with reduced liver cancer risk, no link to biliary tract cancer

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No significant association was observed between coffee consumption and risk of biliary tract cancer, but there was evidence of an inverse correlation between coffee consumption and liver cancer risk.

Mediterranean diet, antioxidant supplements beneficial for non-alcoholic fatty liver disease

Mediterranean diet, antioxidant supplements beneficial for non-alcoholic fatty liver disease

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A Mediterranean diet with antioxidant supplementation contributes to improving lipid profile and insulin sensitivity parameters in patients with non-alcoholic fatty liver disease.

Demand for liver transplant for nonalcoholic steatohepatitis expected to continue

Demand for liver transplant for nonalcoholic steatohepatitis expected to continue

The increase in the demand for liver transplantation for nonalcoholic steatohepatitis is expected to continue with the current population obesity trends.

AAP: Hepatitis B vaccine should be given within first 24 hours of life

AAP: Hepatitis B vaccine should be given within first 24 hours of life

The American Academy of Pediatrics recommends that the first dose of the hepatitis B vaccine should be given within the first 24 hours of life.

Primary care providers and nurse practitioners can expand HCV treatment access

Primary care providers and nurse practitioners can expand HCV treatment access

Primary care providers and nurse practitioners achieve the same sustained virologic response rates as specialists.

Alcohol screening and brief intervention: A practice manual for clinicians

Alcohol screening and brief intervention: A practice manual for clinicians

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The AAFP has created an alcohol screening practice manual to help family physicians prevent alcohol misuse.

Use of palliative care increases in patients with end-stage liver disease

Use of palliative care increases in patients with end-stage liver disease

The use of palliative care increased from 2006 to 2012 among patients with end-stage liver disease.

Electronic health record-based prompt increases hepatitis C screenings in baby boomers

Electronic health record-based prompt increases hepatitis C screenings in baby boomers

The prompt increased hepatitis C screening rates among baby boomers in primary care by 5-fold.

Telbivudine prevents hepatitis B transmission during early pregnancy

Telbivudine prevents hepatitis B transmission during early pregnancy

Telbivudine administered during early and middle pregnancy prevented hepatitis B transmission from mother to infants in all participants receiving antiviral treatment.

WHO updates Essential Medicines List, recommendations for antibiotics

WHO updates Essential Medicines List, recommendations for antibiotics

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The update includes 30 new medicines for adults and 25 for children and groups antibiotics into 3 distinct categories.

Risk-scoring model predicts advanced colorectal neoplasia in younger adults

Risk-scoring model predicts advanced colorectal neoplasia in younger adults

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The score could help predict advanced colorectal neoplasia in adults younger than 50 years of age.

Frequent coffee and herbal tea consumption linked to lower liver stiffness

Frequent coffee and herbal tea consumption linked to lower liver stiffness

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The Rotterdam Study found that frequent coffee and herbal tea consumption is associated with lower liver stiffness in the general population.

High HCV cure rates in patients with HIV coinfection at urban clinic

High HCV cure rates in patients with HIV coinfection at urban clinic

Hepatitis C treatment in HIV coinfection cases is effective with standardized nurse and pharmacist support for patients in an urban clinic.

Hepatitis B vaccine reduces risk of non-Hodgkin lymphoma in adolescents

Hepatitis B vaccine reduces risk of non-Hodgkin lymphoma in adolescents

The universal vaccination against hepatitis B virus infection prevented non-Hodgkin lymphoma in adolescents.

Increased coffee consumption may reduce risk of hepatocellular carcinoma

Increased coffee consumption may reduce risk of hepatocellular carcinoma

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Researchers conducted a meta-analysis to determine the association between coffee consumption and risk of hepatocellular carcinoma.

Tenofovir prevents prenatal transmission of HBV in pregnancy

Tenofovir prevents prenatal transmission of HBV in pregnancy

Pregnant women with a high hepatitis B viral load who receive tenofovir have a reduced risk for passing the virus to their child.

Endoscopy's role in primary sclerosing cholangitis: a clinical guideline

Endoscopy's role in primary sclerosing cholangitis: a clinical guideline

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The guideline is intended to be an educational device to provide information that may assist endoscopists in providing care to patients.

ASCO: Capecitabine may prolong survival in patients with biliary tract cancer

ASCO: Capecitabine may prolong survival in patients with biliary tract cancer

The researchers found that the average survival after surgery for those receiving capecitabine was longer compared with those who only had surgery.

Gluten consumption affects symptom onset in functional dyspepsia

Gluten consumption affects symptom onset in functional dyspepsia

Gluten-rich food may lead to symptom onset, specifically early satiety, in patients with functional dyspepsia.

Primary biliary cholangitis: A clinical practice guideline

Primary biliary cholangitis: A clinical practice guideline

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The guidelines facilitate a holistic, lifelong approach to the management of patients with primary biliary cholangitis.

EASL releases updated guidelines for managing hepatitis B virus infection

EASL releases updated guidelines for managing hepatitis B virus infection

The updated guidelines include substantial changes in the management of hepatitis B based on the latest scientific evidence.

Zinc effective in children with presymptomatic Wilson disease

Zinc effective in children with presymptomatic Wilson disease

Treatment was effective in patients under 6 years who received 50 mg/day of zinc as an initial dose.

HCV transmission knowledge varies among opioid-dependent pregnant patients

HCV transmission knowledge varies among opioid-dependent pregnant patients

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Most opioid-dependent pregnant patients understand that intravenous drug use is a major transmission modality of HCV.

Statins may lower risk of cirrhosis decompensation in HBV and HCV

Statins may lower risk of cirrhosis decompensation in HBV and HCV

Statin use decreased rates of decompensation in patients with liver cirrhosis due to HBV and HCV infections and in patients with alcohol-induced cirrhosis.

AGA Institute releases practice update for managing patients cured of HCV infection

AGA Institute releases practice update for managing patients cured of HCV infection

Patients with chronic HCV infection who have achieved a sustained virologic response with treatment may still be at risk for complications such as hepatocellular carcinoma.

Metastatic pancreatic cancer: a new clinical practice guideline

Metastatic pancreatic cancer: a new clinical practice guideline

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The guideline will help clinicians determine the appropriate treatment of patients with metastatic pancreatic cancer.

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