Melanoma risk elevated in patients with HIV/AIDS

Avoiding unnecessary sun exposure and routine melanoma screenings help protect patients with HIV/AIDS.

  • Melanoma on the Eyelid
  • Melanoma of the Foot (Early Stage)
  • Melanoma of the Foot (Late Stage)
  • Melanoma in the Loin
  • Melanoma on the Arm
  • Melanoma Skin Cells
  • Melanoma of the Neck
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Melanoma

Melanoma risk elevated in patients with HIV/AIDS
Melanoma risk elevated in patients with HIV/AIDS

Regular melanoma screening, as well as counseling to avoid excessive sun exposure, is recommended for patients with HIV/AIDS, according to researchers.

Despite the decrease in AIDS-defining cancers after the introduction of HAART, patients with HIV/AIDS remain at significant risk for melanoma — especially white patients with HIV/AIDS — Catherine M. Olsen, PhD, of the department of Population Health at the QIMR Berghofer Medical Research Institute in Brisbane, Australia, reported in PLOS One.

She and colleagues performed a systematic review and meta-analysis, pooling data using a random effects model from Medline, Embase and ISI science citation index databases on cohort studies including patients with HIV/AIDS examined for melanoma.

Of 288 studies, 21 met inclusion criteria — 13 studies included data during the post-HAART era and eight included data during the pre-HAART era.

The pooled RR for the association between HIV/AIDS and melanoma during the post-and pre-HAART eras was 1.26 (95% CI: 0.97–1.64; 95% CI, 1.11-1.43).

Among studies that adjusted for ethnicity, the pooled RR was 1.50 (95% CI: 1.12–2.01) for the post-HAART era and 1.28 for pre-HAART era (95% CI: 1.10–1.49).

“Whilst sub-group analyses revealed heterogeneity across some study characteristics, the pooled estimates in most sub-groups — most notable for studies that have appropriately adjusted for race/ethnicity and those rated of higher quality on the basis of our quality score — are indicative of a significantly increased risk,” Olsen and colleagues wrote.

Reference 

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