Clinical evaluation of 
peptic ulcer disease

Clinical evaluation of 
peptic ulcer disease

Most often caused by use of nonsteroidal anti-inflammatory drugs or 
bacterial infection, peptic ulcer disease usually presents as epigastric pain.

Recognizing and treating low testosterone in men

Recognizing and treating low testosterone in men

There is a direct correlation between testosterone and metabolic syndrome, mental function, libido, erectile dysfunction, bone density, and overall energy.

Primary-care prevention of cervical cancer

Primary-care prevention of cervical cancer

To reduce the mortality and incidence of this disease, clinicians must be aware of the most recent vaccination and screening guidelines.

Evaluation and treatment of acute cerebral ischemia

Evaluation and treatment of acute cerebral ischemia

To ensure that therapeutic interventions begin in time, providers must be able to recognize the clinical presentation of an acute ischemic stroke.

New paradigms in managing chronic kidney disease

New paradigms in managing chronic kidney disease

To slow the progression to end-stage renal disease, primary-care clinicians must be able to identify, screen, treat, and educate at-risk individuals.

A collaborative approach to myasthenia gravis

A collaborative approach to myasthenia gravis

This chronic autoimmune disorder is caused by antibodies that block muscle cells from receiving neurotransmitters from the nerve cell.

Updated standards for CCHD screening: Pulse-oximetry pearls and statewide protocols, Part 3

Updated standards for CCHD screening: Pulse-oximetry pearls and statewide protocols, Part 3

Improved pulse-oximetry standards translate into more sensitive critical congenital heart disease screening.

Detection of hypoxemia: 
Visual observation 
versus pulse oximetry, Part 1

Detection of hypoxemia: 
Visual observation 
versus pulse oximetry, Part 1

Early diagnosis is essential to providing treatment in infants with critical congenital heart disease.

Infections, tumors and lumps affecting the scrotal content

Infections, tumors and lumps affecting the scrotal content

A lump, enlarging scrotum or pain can conjure up images of testicular ­cancer, but other conditions involving the scrotal content are possible.

Evaluating and managing 
pediatric food allergy

Evaluating and managing 
pediatric food allergy

An approach involving primary-care clinicians, and specialists — including 
allergists, gastroenterologists, nutritionists and counselors — is crucial.

Oral involvement of ­systemic diseases

Oral involvement of ­systemic diseases

Oral manifestations are often an early signal of systemic disease, so ­recognizing them can point the way to a prompt diagnosis.

HAART meds: Implications for the older adult patient

HAART meds: Implications for the older adult patient

Patients infected with HIV are living longer, which means they have more age-related comorbidities that require other medications as well.

A new understanding of 
osteoarthritis

A new understanding of 
osteoarthritis

Ongoing research and new developments hold promise for altering 
osteoarthritis and go beyond simply treating the symptoms.

Helicobacter pylori: Toward effective eradication

Helicobacter pylori: Toward effective eradication

When choosing among the available treatment options, consideration must be given to local prevalence and antibiotic resistance.

A practical guide to 
metabolic syndrome

A practical guide to 
metabolic syndrome

With obesity on the rise, more patients are at risk for metabolic 
syndrome, a diagnosis given to a set of simultaneous disorders.

Lupus and the autoimmune process in 2012

Lupus and the autoimmune process in 2012

Thanks to new prevention strategies and safer treatments, patients are surviving almost as long as their counterparts without lupus.

Urinary incontinence in the older female population

Urinary incontinence in the older female population

Despite what clinicians and patients think, accurate evaluation and targeted interventions can relieve symptoms and improve quality of life.

Management of diabetic 
ketoacidosis in adults

Management of diabetic 
ketoacidosis in adults

When developing a plan of care for individuals in diabetic ketoacidosis — an acute complication of diabetes — search for the inciting stressor.

Dyspnea with comorbid heart failure and COPD

Dyspnea with comorbid heart failure and COPD

There are guidelines for the management of each as a separate condition, but how do you evaluate and treat them when they appear together?

Screening for functional deficits in older adults

Screening for functional deficits in older adults

Assessment of functional impairments in an aging population is one of the most daunting challenges facing primary-care clinicians.

Therapeutic strategies for bacterial conjunctivitis

Therapeutic strategies for bacterial conjunctivitis

Resistance has compromised the effectiveness of all ophthalmic antibiotics, but new topical treatment options are available.

Taking back control: the fight against obesity

Taking back control: the fight against obesity

As obesity rates continue to rise, primary-care clinicians remain integral in assessing, diagnosing, and treating this worldwide epidemic.

Treatment guidelines for Alzheimer-type dementia

Treatment guidelines for Alzheimer-type dementia

The most common dementia in the elderly, Alzheimer disease places tremendous physical and emotional strain on patient and caregiver alike.

An update on treatments for sleep disorders

An update on treatments for sleep disorders

Insomnia affects the mind as well as the body. Treatment should combine psychological intervention, behavioral change, and possibly drug therapy.

Gouty arthritis: How to make the diagnosis

Gouty arthritis: How to make the diagnosis

This painful disease greatly impacts the daily lives of those who suffer from it. Diagnosis, treatment, and lifestyle modification can ease long-term effects

Diagnosis and management of celiac disease in adults

Diagnosis and management of celiac disease in adults

As this condition becomes more prevalent in primary care, clinicians need to emphasize the importance of lifelong adherence to a gluten-free diet.

Treating giant cell arteritis to avoid complications

Treating giant cell arteritis to avoid complications

Seen primarily in individuals older than age 50 years, this inflammatory disorder is characterized by headache, jaw pain, and vision difficulties.

Infants with hypopigmented processes

Infants with hypopigmented processes

Two patients present with similar hyperpigmented spots on the skin — one with a series of macules on the cheek, and the other with lesions on his back.

Keratotic palms paired with brittle nails

Keratotic palms paired with brittle nails

A 42-year-old man presented with abnormally thick skin of the palms.

Nonhealing hand ulcer turns erythematous

Nonhealing hand ulcer turns erythematous

A woman aged 34 years was referred for treatment of a recurrent, painful, nonhealing ulcer of six months' duration on her left hand.

Oral lesions caused by human papillomavirus

Oral lesions caused by human papillomavirus

Commonly found in the oral cavity, HPV lesions may persist or relapse spontaneously and occasionally require surgical excision.

Controversy over fish oil's cardioprotective effects

Controversy over fish oil's cardioprotective effects

Trial results poured cold water on claims that omega-3s prevent heart attacks. What does the future hold for these popular supplements?

Scaly papules in sun-exposed areas

Two patients present with scaly papules. One presented to the dermatology clinic with an eight-month history of an asymptomatic progressive rash on his arms and legs, and the other patient had a history of multiple nonmelanoma skin cancers with asymptomatic scaly lesions on his hands, arms and head.

Slightly erythematous, scaly scalp lesion

Slightly erythematous, scaly scalp lesion

A 10-year-old boy referred by his pediatrician presented with a six-week history of a scaly scalp lesion.

Rash on palms and arms and blister on lower lip

Rash on palms and arms and blister on lower lip

A 28-year-old woman presents with a burning rash on her palms and arms. The rash appeared abruptly two days earlier along with numerous flat, pinkish-red lesions.

Nonhealing but painless cheek ulcer

Nonhealing but painless cheek ulcer

A Hispanic man age 23 years presented with a nine-month history of a nonhealing ulcer of his cheek. The erosion began as a small, painless erosion and had gradually enlarged.

Blisters on the lip and in the mouth

Blisters on the lip and in the mouth

A 35-year-old white woman presented with grouped vesicles and superficial crusting on both lips and grouped erosions on the gingiva and hard palate.

Papules caused by insect bites

Papules caused by insect bites

Two patients present with insect bites — one after walking in brush while vacationing and another after doing yard work. Can you differentiate between the two?

New strategies to treat primary dysmenorrhea

New strategies to treat primary dysmenorrhea

Painful menstrual cramps are a quality-of-life issue for many. Clinicians should know what nonpharmacologic treatment options are available.

Osteoporosis screening in postmenopausal women

Osteoporosis screening in postmenopausal women

New management strategies include the use of Web-based tools, an emphasis on lifestyle approaches, and early pharmaceutical intervention.

Arm lesions spread to the trunk and neck

Arm lesions spread to the trunk and neck

Asymptomatic erythematous papules on the arms, trunk, and neck are first thought to be insect bites in a man with weight loss, fatigue, and dyspnea.

Discoloration of the face, neck and hands

Discoloration of the face, neck and hands

A man taking an alternative medical treatment for periodontal disease presents with a history of skin discoloration.

Dystrophies of the nail

Two patients present with dystrophies of the nail—one with a several-year history of yellowed toenails and the other with grooved thumbnails.

Screening for functional deficits in older adults

Screening for functional deficits in older adults

Assessment of functional impairments in an aging population is one of the most daunting challenges facing primary-care clinicians.

Red lesions on the extremities

Two women present with similar red lesions on the extremities—one thought she had ringworm, and the other became severely ill after getting several vaccinations.

Bilateral netlike rash on the lower legs

Bilateral netlike rash on the lower legs

To combat cold temperatures at work, a woman kept a small heater under her desk. This led to netlike erythema on both lower legs.

Vesicle on the lip after intense sun exposure

Vesicle on the lip after intense sun exposure

A man presents with a six-month history of oral lesions that led to blistering and ulceration following intense sun exposure.

Tissue changes associated with vaginal atrophy

Tissue changes associated with vaginal atrophy

Developing effective treatment regimens requires an understanding of how tissue changes are affected by estrogen or alternative therapies.

Cutaneous lesions

Cutaneous lesions

Two patients present with similar cutaneous growths—one a series of ulcerative lesions on the lower leg, and the other a painless forearm lesion.

Tender, edematous, red plaques on a woman's hands and feet

Tender, edematous, red plaques on a woman's hands and feet

One month after starting a new chemotherapeutic drug, the patient sought treatment for painful peeling and redness on her hands and feet.

Exposure to moisture leads to palmar rash

Exposure to moisture leads to palmar rash

A woman presents with a painful rash that developed immediately after exposure to water or sweating and disappeared an hour after drying.

Imaging options for patients with acute abdominal pain

Imaging options for patients with acute abdominal pain

Each of the three primary modalities—plain films, diagnostic ultrasound, and CT scan—must be weighed against their strengths and weaknesses.

Patches of hair loss

Patches of hair loss

Two boys with similar patches of hair loss—one developed six months ago, and the other had been present since birth.

Kitchen work worsens pruritic hand lesions

Kitchen work worsens pruritic hand lesions

A restaurant employee's intensely itching and burning hand lesions worsened after he was assigned to work in the kitchen.

Recurrent erosions on the neck and axillae

Recurrent erosions on the neck and axillae

For two years, a woman had lived with an itchy rash on her axillae and neck that became more symptomatic during the summer.

Alzheimer's management from diagnosis to late stage

Alzheimer's management from diagnosis to late stage

Caring for a patient with Alzheimer's disease involves more than assessment and treatment. Education and legal issues must also be considered.

Common pediatric hip diseases in primary care

Common pediatric hip diseases in primary care

Left untreated, these childhood conditions could have lasting effects. Our experts explain three of the most common hip disorders you'll see.

Enlarging back and shoulder lesions

Enlarging back and shoulder lesions

Two patients with enlarging lesions—one in a man with no history of skin cancer, and the other in a man with significant actinic damage

Rash preceded by fever and cough

Rash preceded by fever and cough

After four days with a high fever, cough, and conjunctivitis, a child is brought to the hospital with an extensive, maculopapular rash.

Scaly plaques spread from head to toe

Scaly plaques spread from head to toe

Five months of treatment with corticosteroids and antibiotics did not relieve the scaly rash on a man's scalp, cheeks, trunk, genitals, and legs.

New drug options for dementia and Parkinson's disease

New drug options for dementia and Parkinson's disease

A thorough understanding of the therapies available to patients with dementia or Parkinson's disease is essential to improving outcomes.

Red rashes on the lower legs

Two patients present with leg rashes. One rash developed after a woman started taking cefazolin, and the other featured the deposition of hemosiderin.

Vulvar pruritus with no erosions or papules

Vulvar pruritus with no erosions or papules

A woman with no history of sexually transmitted diseases suffers intense vulvar itching. Hypopigmentation was noted with no erosions or papules.

Flesh-colored nodules on the shins and feet

Flesh-colored nodules on the shins and feet

A middle-aged woman with Graves' disease presented with asymptomatic, firm, nonpitting, flesh-colored nodules and plaques on her legs and feet.

Hypopigmented patches on the body

Two young girls with hypopigmented patches—one on the right buttock, the other on the knees, fingers, and ankles.

Rapidly growing tumor on the forearm

Rapidly growing tumor on the forearm

Six weeks after it appeared, the small red bump on this man's right forearm had become an erythematous crater-shaped nodule

Shiny, waxy patches on the shins

Shiny, waxy patches on the shins

A woman with a history of type 2 diabetes presented with asymptomatic, shiny, waxy, round patches on her shins that turned from red to yellow.

Oral pathology for the primary-care clinician

Oral pathology for the primary-care clinician

Become familiar with the cause, characteristics, and appropriate treatment of the most frequently seen conditions of the mouth, tongue, and gums.

Atrophic rash in a hepatitis C patient

Atrophic rash in a hepatitis C patient

Plaques develop on the face, trunk, and hands of a man with hepatitis C.

Painful tightening of the skin on the legs

Painful tightening of the skin on the legs

A 62-year-old man with a painful erythematous rash on the shins

Purple eruptions

Purple eruptions

Two patients with purple lesions and no other abnormal skin findings.

What lies behind the vitamin D revolution?

What lies behind the vitamin D revolution?

Once known primarily for maintaining bone strength, vitamin D is now thought to contribute to prevention of colon, prostate, and breast cancers.

Erythematous truncal plaques

Erythematous truncal plaques

Two patients with erythematous trunk plaques—the first developed eight months earlier, and the other 15 years ago.

Pressure-induced bumps and erythema

Pressure-induced bumps and erythema

A man presents with complaints of itchy and uncomfortable red bumps on his skin at sites of pressure. The lesions typically dissipated after one hour.

Topical treatment turns ulcer pruritic

Topical treatment turns ulcer pruritic

A woman develops severe itching and burning two days after application of topical bacitracin and a compression bandage to a venous stasis ulcer.

Adult depression: Treating by subtype for success

Adult depression: Treating by subtype for success

Instead of attempting to treat the broad categories, primary-care clinicians should focus on symptoms or features that identify a specific subtype.

Vesiculobullous eruptions

Two patients present with similar vesiculobullous eruptions. One was preceded by painful mouth sores, the other had no oral involvement.

Caring for the geriatric patient: The initial visit

Caring for the geriatric patient: The initial visit

Use the first visit to get as much information as possible about the patient's condition, functional status, and social situation.

Cold blue fingers in a Coloradan

Cold blue fingers in a Coloradan

After moving to Colorado, a woman notices painful blue discoloration of her fingers on exposure to the cold.

White areas on the face of a teenager

White areas on the face of a teenager

Fearing a bacterial infection, a teenager seeks treatment for white facial patches.

Intrauterine Contraception: Who, Why, and How

Intrauterine Contraception: Who, Why, and How

Target Audience: Nurse practitioners with an interest in contraception.This monograph focuses on intrauterine contraception, featuring a case-based look at identifying appropriate contraceptive choices that factor in an individual woman's medical needs,reproductive goals, age, and lifestyle.

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