Therapeutics to cool the brain may someday be a safer alternative to hypnotics.
In patients with paradoxical insomnia, also called sleep state misperception, there is a significant discrepancy between objective sleep quality and subjective perception of sleep.
A normally healthy 7-year-old female complained of "not feeling good," and her pediatrician noted that she had a unilateral lymphadenopathy in her right axilla.
Suspecting that this phenomenon might be the source of my nighttime pain, causing significant REM sleep deprivation, I reasoned that a neuromodulator such as a gabapentinoid might be helpful.
Mr J was an 89-year-old man with a long history of problems voiding due to increasing benign prostatic hyperplasia.