Image of the Week: How would you manage this drug-induced reaction?

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A 55-year-old man is diagnosed with infective endocarditis 2 weeks after undergoing dental surgery; antibiotic therapy is initiated. A few minutes into commencing a rapid infusion of vancomycin, he develops flushing, erythema, and pruritus on his face, neck, and chest. He reports a diffuse burning sensation and generalized discomfort. After stopping the infusion, how would you proceed with this patient's treatment? Learn more about this case and join the conversation on Figure 1.

 

 

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