Infectious Disease News Archive
Elbasvir and grazoprevir, taken in combination for 12 weeks, successfully treated virologic response in patient with hepatitis C genotype 1b.
During cold/flu season there is an increase in acetaminophen use and overdosing.
The first set of blood screening tests for the tickborne parasite Babesia microti have been approved by the US Food and Drug Administration.
A new antiretroviral HIV treatment, Trogarzo (ibalizumab-uiyk), has been approved by the FDA for patients with HIV who have not have success with past HIV medications.
Increasing awareness of and access to newer HIV testing options such as free or reduced price on home and self-tests and couples HIV testing and counseling can facilitate increased levels of consistent testing among young, Black MSM, and transgender women.
Bacterial vaginosis may cause an increased risk for HIV acquisition in women taking oral or injectable hormonal contraception.
Technical variant grafts may be better than whole grafts for living donor liver transplants in children.
Excessive alcohol consumption does not impact the decline of CD4 cell count in patients with HIV who have not undergone antiretroviral treatments.
Chronicity of depression is associated with increased likelihood of failure along the continuum of HIV care.
Undergoing cardiac surgery during the influenza season is associated with increased likelihood of development of acute respiratory distress syndrome.
The risk of invasive pneumococcal disease is correlated with the prescription opioid use.
The Work Group who authored the new recommendations was made up of professionals from academic medicine, federal and state public health agencies, and medical societies.
Once daily glecaprevir-pibrentasvir for 8 or 12 weeks successfully treated HCV genotype 1 and 3.
The USPSTF reports that pregnant women can benefit from screening for syphilis infection.
The 2017 to 2018 influenza vaccine reduces the chance of getting the disease by about 33%, but is only 25% effective against H3N2, otherwise known as influenza A.
Primary gastrinomas of the hepatobiliary tract may occur in patients with Zollinger-Ellison syndrome
Lymph nodes proximal to hepatic or biliary gastrinomas will likely require extraction as many in the surround region will have metastasized.
Patients with chronic HCV with a sustained virologic response were more likely to have a reduced progression of liver fibrosis.
Influenza infections are independently compartmentalized in the upper and lower airways.
Hydrocortisone treatment does not effectively reduce mortality in sepsis.
Herpes zoster subunit vaccine more effective, less expensive than live attenuated herpes zoster vaccine
The adjuvanted herpes zoster subunit vaccine is more effective and less expensive than the live attenuated herpes zoster vaccine at all ages.
Younger adults are more likely to have provider-ordered flu testing than older adults.
For young adults without known risk factors, a one-time routine HIV screen at 25 years would optimize clinical outcomes and be cost-effective.
Intensive care and death were greatly prevented in patients who were annually vaccinated.
An outbreak of E. coli O157:H7 have been reported in 13 states in the US as well as Canada.
Men may experience a lower immune response than women, adding insight to the man flu debate.
Inactivated and live attenuated flu vaccines can be safely administered to people with egg allergies.
Post-seroconversion brain morphology can occur in HIV patients, but aviremia maintenance via cART can slow of prevent brain injuries.
A new report from the CDC finds that HIV is being diagnosed sooner after initial infection than in previous years.
Nivolumab treatment for non-small-cell lung cancer may induce successful depletion of HIV reservoir.
The decrease in HIV incidence in Uganda was facilitated by antiretroviral therapy, male circumcision, and adolescent abstinence.
Clinician suspicion has minimal accuracy for the diagnosis of Lyme disease.
A Minnesota-based hospital chain fires about 50 employees for refusal to receive the influenza vaccine.
The Food and Drug Administration (FDA) has approved Heplisav-B for the prevention of infection caused by all known subtypes of hepatitis B virus.
New virus mutations make antibody binding difficult as mismatches in vaccines and viruses emerge.
More tests might be administered to transgender individuals who are female, black, or sex workers.
A pneumonia vaccine under development provides the most comprehensive coverage to date and alleviates antimicrobial concerns.
The dual combination of dolutegravir plus darunavir/ritonavir provided a simple and safe salvage therapy to suppress viral replication without metabolic impact in patients infected with HIV-1.
Hepatitis B and hepatitis C may increase mortality risks in HIV patients.
The Ohio Supreme Court has unanimously upheld the constitutionality of a law requiring HIV-infected individuals to tell their sexual partners of their illness.
The CDC revised its US Medical Eligibility Criteria for Contraceptive Use categorization for DMPA injection in women at high risk for HIV infection from US MEC category 1 to US MEC category 2.
Resistance to ART is threatening the recent gains of treatment in the rate of new HIV infections.
A combination antibiotic regimen with a macrolide was shown to improve short- and long-term outcomes in patients with community-acquired pneumonia.
A 38-year old nonalcoholic patient consumed Epsom salt in large quantities for a short period of time and developed jaundice and steatohepatitis.
Researchers developed a clinical tool to predict prolonged hospital stays in patients with pediatric community-acquired pneumonia.
The AAP has updated guidelines on infection prevention and control that include the endorsement of immunization for healthcare personnel and guidance during outbreaks of infectious diseases.
More than half of women receiving a new HIV diagnosis have already received this diagnosis in the past but are not undergoing HIV medical care.
Mislabeling of herbal and dietary supplements is common, occurring in more than half of products tested.
Aspirin therapy is associated with a reduced risk of hepatitis B virus-related hepatocellular carcinoma.
The American Association for the Study of Liver Diseases and the Infectious Diseases Society of America have added updates to the hepatitis C guidelines to include kidney transplant, pregnant, and pediatric patients.
Infection was diagnosed at an early stage for fewer males with infection attributed to heterosexual contact vs male-to-male sexual contact.
In the 1 to 10 days after flu vaccine administration, there was no increased risk for VTE.
Greater positive mood significantly predicted greater antibody responses to the influenza vaccination.
With a continuing resurgence in pertussis, efforts should focus on maximizing Tdap uptake among pregnant women.
The researchers found that 42% of the estimated 12 million ever-employed adults with current asthma had received a pneumococcal vaccine.
The HIV Medicine Association of the Infectious Disease Society of America recommends that people living with HIV be screened for pain and offered both nonpharmacologic and pharmacologic treatment options.
Virological response, efficacy, noninferiority, and tolerability were tested for bictegravir, emtricitabine, and tenofovir alafenamide in patients with HIV.
The FDA has approved Opdivo (nivolumab) injection for the treatment of patients with HCC who have been previously treated with sorafenib.
According to the report, 1.6 million cases were chlamydia, and there were 470,000 cases of gonorrhea and almost 28,000 primary and secondary syphilis cases.
In 16 countries, notification rates for new HIV diagnoses in older adults increased significantly, clustering in central and eastern European countries.
The 3-part plan to halt the outbreak of hepatitis A focuses on immunization, sanitation and education with most of the efforts focused on the homeless population who are the most at-risk population.
The results show no evidence to support a hypothesis of differential impact of interferon and direct-acting antiviral-based cure on risk for HCC occurrence and recurrence.
Elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide was well tolerated in children and maintained high virological suppression.
Patients with childhood-onset IBD have an increased risk of cancer, especially gastrointestinal cancers, lymphoid neoplasms, and skin cancer,
High-dose vitamin D supplements improve bone mineral density in youth with HIV.
Alternative treatments should be offered to pregnant women with HIV instead of tenofovir or emtricitabine.
Smartphone-based electronic reader reliable for point-of-care tests in HIV and T pallidum infections
The findings shed new light on the applicability of smartphone-based electronic readers in point-of-care testing.
The guidelines include a strong recommendation for annual seasonal influenza immunization for everyone 6 months and older.
Total influenza vaccination rates among children in the 2016 to 2017 influenza season dropped 1.6% from the year before.
Digital immunoassays and rapid nucleic acid amplification tests have higher sensitivities for detecting influenza than rapid influenza diagnostic tests.
Adherence decreased over time in adolescent MSM who participated in a 48-week HIV PrEP intervention.
No significant association was observed between coffee consumption and risk of biliary tract cancer, but there was evidence of an inverse correlation between coffee consumption and liver cancer risk.
A Mediterranean diet with antioxidant supplementation contributes to improving lipid profile and insulin sensitivity parameters in patients with non-alcoholic fatty liver disease.
The increase in the demand for liver transplantation for nonalcoholic steatohepatitis is expected to continue with the current population obesity trends.
The Advisory Committee on Immunization Practices has released the guidelines for the 2017-2018 season.
The FDA has approved benznidazole to treat the tropical parasitic infection Chagas disease in children.
This approval provides an additional treatment option for patients with complicated urinary tract infection.
The American Academy of Pediatrics recommends that the first dose of the hepatitis B vaccine should be given within the first 24 hours of life.
Men who are admitted to the hospital with a serious infection may have an increased risk of cardiovascular disease in the years immediately following the infection.
Hypoxia, increased work of breathing outweigh tachypnea, auscultatory findings in diagnosing pneumonia
No single clinical observation reliably differentiates pneumonia from other causes of respiratory illness in children.
Researchers observed excess community-acquired infections incidence in individuals with mild to severe chronic kidney disease.
Researchers found the H3N2 virus in swine at state fairs in Ohio and Michigan, which was transmitted to humans.
Primary care providers and nurse practitioners achieve the same sustained virologic response rates as specialists.
The live attenuated vaccine was ineffective among children between 2 and 17 years of age during the 2015-2016 season.
Researchers found that in a cohort of pregnant women, receipt of influenza vaccine the previous year predicts higher baseline antibody titers and decreased peak antibody responses against all influenza strains.
Women with mental illness engage in significantly more sexually risky behaviors than men, and personality risk scores are a significant predictor of total sex acts for women but not men.
Rapid HIV testing offered in parallel to patient-clinician consultations increases the testing rate in the emergency department.
The new guidelines address the issue of how to manage pretreatment HIV drug resistance in countries where the prevalence of is 10% or higher.
A child who was diagnosed with HIV at 1 month and received early treatment has suppressed the virus without anti-HIV therapy for 8.5 years.
The AAFP has created an alcohol screening practice manual to help family physicians prevent alcohol misuse.
The use of palliative care increased from 2006 to 2012 among patients with end-stage liver disease.
The prompt increased hepatitis C screening rates among baby boomers in primary care by 5-fold.
A rare case reports a 51-year-old man who primarily presented with multiple nodules on his scalp.
The hospital and ICU mortality rates of critically ill patients with VZV-CAP were 24% and 17%, respectively.
The risks of both stroke and myocardial infarction were highest the first year after the onset of herpes zoster and decreased with time.
About half of patients accepted influenza vaccination for their child if the clinician used a presumptive vs participatory initiation format.
Algal blooms produce toxins that can cause illness in people and animals and can block sunlight or use up oxygen in water, which can kill fish and plants.
Telbivudine administered during early and middle pregnancy prevented hepatitis B transmission from mother to infants in all participants receiving antiviral treatment.
The investigators found that after 32 weeks, HIV remained suppressed in 91% percent of those taking the drugs orally, 94% of those receiving monthly injections, and 95% of patients receiving injections every two months.
HIV, hepatitis B, and hepatitis C infections are more common among individuals with severe mental illness.
The update includes 30 new medicines for adults and 25 for children and groups antibiotics into 3 distinct categories.