Infectious Disease News Archive
An outbreak of flea-borne typhus in Los Angeles County has so far resulted in 57 cases, including 20 in Pasadena and 9 in downtown Los Angeles.
The approval of the expanded age range was based on data from a clinical trial which evaluated the efficacy of Gardasil (quadrivalent human papillomavirus recombinant vaccine) in 3253 women 27-45 years of age with a median duration of follow-up of 3.5 years post-dose 3.
One of the goals of the US Department of Health and Human Services National Viral Hepatitis Action Plan is to eliminate mother-to-infant transmission of HCV infection.
Investigators examined treatment response of sofosbuvir-based DAA in patients with chronic hepatitis C with compensated liver cirrhosis in a community care setting.
Wide variations in influenza vaccine coverage have been noted across healthcare personnel based on occupation and worksite.
Analysis of 2 phase 3 clinical trials evaluating the safety/efficacy of glecaprevir/pibrentasvir in people with HCV coinfected with HIV-1 found an overall sustained virologic response of 98% at week 12 of treatment in those with or without cirrhosis.
Active Choice Intervention Effective in Increasing Influenza Vaccination Rates at Primary Care Practices
Influenza vaccination rates decline as the clinic day progresses.
For patients with CAP, antibiotic regimens including a fluoroquinolone may reduce mortality risk by 1-2% compared to beta-lactams and cephalosporins alone.
In patients taking multiple antibiotics, proton pump inhibitors, or histamine receptor antagonists, the concurrent use of probiotics was associated with an increased incidence of Clostridium difficile infection
A combination single tablet once-a-day regimen of doravirine/lamivudine/tenofovir disoproxil fumarate demonstrated non-inferiority and no significant adverse events when compared with continuation of established antiretroviral therapy in adults infected with HIV-1.
A documented β -lactam allergy was found in more than one-third of patients receiving broad-spectrum antibiotics, however, only 10% of patients were found to be truly allergic.
The use of a moderate to low susceptibility antibiotic to treat a urinary tract infection [UTI] may result in a 1.74-fold increase in the odds of an emergency department readmission within 30 days for another UTI.
The first human case of a strain of hepatitis E previously found only in rats was diagnosed in a Hong Kong man who received a liver transplant in May 2017.
Ten to 14 days after being hung, curtains show increased MRSA positivity.
Barriers found among PCPs in surveillance of HCC indicate the need for clinical interventions, including provider education.
2017 to 2018 flu strains hit the very young and elderly especially hard; poor vaccine/strain match-up.
Congenital syphilis up from 362 cases in 2013 to 918 in 2017, with 46.17% increase since 2016.
Number of HIV diagnoses in those aged 13 to 29 4x higher than those aged 50 years.
Beef was produced and packaged at Cargill Meat Solutions in Fort Morgan, Colo.
The PELD score underestimates the actual probability of 90-day pretransplant mortality for children undergoing a primary liver transplant.
Inspection at the VIP Spa in Albuquerque detected practices that might spread HIV or hepatitis B and C.
As infections from drug-resistant microbes continue to rise, the development of new antibiotics has declined since the golden age of antibiotic discovery in the mid-20th century.
Curing HCV infection with direct-acting antiretrovirals is associated with regression of liver fibrosis for most patients.
Live chicks, ducklings obtained from relatives, feed supply stores, websites, and hatcheries.
Bisexual females, 'not sure' males have higher prevalence of many sexual risk behaviors.
The researchers found a significant difference in mean time to direct-acting antiviral agent treatment among participants with public insurance payers compared with private insurance payers.
The neuropsychiatric symptoms associated with HCV infection are likely caused by the body's response to the virus' effects on brain function.
A robust anamnestic response was mounted in most adolescents when challenged with a dose of monovalent HBV vaccine.
All children age 6 months and older, including teens, advised to undergo annual immunization.
There is an opportunity to improve HCV treatment rates for people who inject drugs by integrating DAA therapy into current models of community-based addiction.
Direct-acting antivirals are safe and effective in African-American patients with chronic HCV.
Expression of KLRD1 by natural killer cells before infection associated with influenza severity.
Nearly 2.3 million total cases of chlamydia, gonorrhea, syphilis diagnosed in the United States in 2017.
Decision made 'out of an abundance of caution and concern for the safety of students and employees'.
Specimens of the rapidly evolving virus are needed to develop vaccines and treatments.
Delstrigo is approved as a complete regimen whereas Pifeltro is to be administered in combination with other antiretrovirals.
To date, 8 people have been hospitalized and 1 patient has died.
Compared with uninfected individuals, people with HIV controlled with combination antiretroviral therapy are not at increased risk of developing thyroid dysfunction.
Patient navigation may be considered an effective strategy to enhance engagement and continuation in disease treatment among people with HIV.
In general, routine annual vaccination is recommended for all patients ≥6 months of age who have no contraindications.
Lower odds of having detectable viral load for older adults and those using ISTI-based regimen.
In high-volume centers, patients with liver metastases from colorectal cancer may often be eligible for minimally invasive liver surgery via laparoscopy, thereby reducing potential morbidity risks associated with open surgery.
Lower degree of susceptibility to ibalizumab for 9 of 10 patients with virology failure, rebound.
The International Antiviral Society-USA Panel has updated its recommendations for the management and prevention of HIV infection, to reflect the most current data on new treatment regimens and strategies.
Intervention group had greater reduction in condomless sex acts vs standard of care group.
A systematic literature review, published in Clinical Infectious Diseases, found no evidence supporting a benefit to antibacterial therapy for osteomyelitis in patients with stage IV sacral pressure ulcers.
Close to one-third of sexually active HIV-positive men who have sex with men (MSM) have not received syphilis screening in the past 12 months.
First to be vaccinated will be health workers, contacts of confirmed Ebola patients.
Findings among teens diagnosed with pelvic inflammatory disease in the emergency department.
Asian longhorned tick currently considered a greater threat to livestock than to humans.
All 20 recipients experienced HCV cure, good quality of life, excellent renal function.
Sensitization to Aspergillus fumigatus increased the risk for severe asthma.
Enterococci bacteria surviving exposure for longer periods of time.
Circulating hepatic markers may predict the risk for diabetes in women.
ART recommended for almost all HIV-infected; should be initiated as soon as possible post diagnosis.
Women receiving the inactivated influenza vaccine demonstrated superior antibody response compared with those receiving the live attenuated influenza vaccine.
Investigators added hepatitis C virus and HIV screening tests to standard trauma activation laboratory orders.
Drop in median price of WHO-prequalified generic tenofovir from 208 to 32 from 2004 to 2016
Vaccinated women and girls living with HIV may be at greater risk for HPV vaccine failure compared with women and girls without HIV.
Coordinated treatment programs may improve treatment outcomes in patients with hepatitis C infection.
Infectious disease experts from Emory University School of Medicine recommend that patients contemplating travel to Zika-affected areas consult with their care providers regarding travel plans and potential Zika virus testing.
Adults aged 25 to 34 show greatest relative increase in mortality, driven by alcoholic cirrhosis.
Fidaxomicin demonstrated the strongest evidence for being the most effective treatment in providing a long-term cure for C difficile infection.
Single high-dose liposomal amphotericin B (L-AmB) is non-inferior to daily dosed L-AmB at the standard dose in treatment of fungal clearance in HIV-associated cryptococcal meningitis.
Illnesses appear to be caused by Vibrio parahaemolyticus bacteria.
A study was conducted to evaluate the oxazolidinone resistance mechanisms of enterococci bacteria.
As of end of May 2018, 199 cases of salmonellosis identified that were linked to kratom consumption.
Inverse association identified between NME rate and MMR vaccine coverage of kindergarteners.
The administration of PCV7 and PCV13 reduced the number of ambulatory visits for otitis media in pediatric patients.
Results - including the date you were checked and a list of what you were checked for - can be shared by users through text, e-mail or on dating profiles.
Using state- and individual-level data from the 1995-2014 National Immunization Survey, the effect of a state's Universal Purchase adoption on vaccination rates was estimated.
Adherence and completion to multidose vaccine schedules for hepatitis A, B, and A-B are low, thereby rendering vaccination ineffective.
Estimated annual incidence of viral meningitis is 2.73 per 100,000 UK adults.
According to the CDC, outbreak that started in the spring and is now over
Cirrhosis is associated with an increased risk for diabetes mellitus among patients living with HIV.
Project ECHO at Los Angeles Christian Health Center contributes to improved care of HCV in underserved populations.
From 2007 to 2015, the majority of initial hepatitis A, B, and A/B vaccinations were administered by primary care providers.
The 2017-2018 influenza season in the United States (October 1, 2017-May 19, 2018) was a high-severity season.
No increased risk of depression or suicidal ideation among persons living with HIV in Uganda.
Annual occasion is a good time for health care providers to encourage testing
The CDC has identified an increasing number of Shigella isolates that test within the susceptible range for the fluoroquinolone antibiotic ciprofloxacin.
ACX-362E is a targeted, narrow spectrum oral antibiotic that blocks the DNA replication process through inhibition of polymerase III, which has been shown to be bactericidal.
First documented case of Keystone infection in a human.
Twenty-four people have been hospitalized, but no deaths have been reported.
Although heads of state and governments have pledged to reduce premature mortality from noncommunicable diseases by one-third by 2030, many countries are not on track to achieve this goal.
Patients with chronic hepatitis B have a lower risk of hepatic events if they achieve normal on-treatment ALT in the first 12 months of NA treatment.
Increase seen carbapenem- and cephalosporin-resistant strains, with peak in 2008
Of the 2500 cases of hepatitis A infection reported between January 2017 and April 2018, 68% were among persons who reported drug use (injection and non-injection), homelessness, or both.
31 people have been hospitalized; no deaths reported to date.
Successful DAA therapy may lead to cognitive improvement in several domains in HCV-infected patients.
Costs were significantly higher than total annual costs per matched control with similar comorbidities.
Lyme neuroborreliosis diagnosis had no substantial effect on long-term survival, health, or educational/social functioning yet may be associated with an increased risk of hematologic and nonmelanoma skin cancers.
197 cases of illness linked to the E coli outbreak, 5 of which were fatal
Low screening rate seen at same time as increase in hepatitis C virus prevalence among pregnant women
The Respectful & Equitable Access to Comprehensive Healthcare program obtained 93% of prior authorization approvals for hepatitis C medications.
A proposed novel Medicaid purchasing strategy is anticipated to increase access to medications that can eradicate hepatitis C virus infection without increasing costs at the state and federal levels.
Outbreaks with confirmed infectious etiology usually caused by Cryptosporidium, Legionella, Pseudomonas
Patients with mild, moderate renal impairment showed improvement in renal biomarkers over one year
The CDC recommends 2 doses of the MMR vaccine, which provides 97% protection against measles, prior to international travel.
Humoral response seen for 97.8% of HZ/su vaccine recipients vs 2% of placebo