Infectious Diseases

Norepinephrine shortage led to higher mortality in septic shock patients

Norepinephrine shortage led to higher mortality in septic shock patients

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Patients with septic shock taking phenylephrine during the 2011 norepinephrine shortage experienced higher in-hospital mortality rates.

Almost half of men and women under 60 in the US infected with HPV

Almost half of men and women under 60 in the US infected with HPV

However, the HPV vaccine has the potential to reverse the epidemic and prevent thousands of cancers in the United States each year.

Preventing chronic diseases with lifestyle changes

Preventing chronic diseases with lifestyle changes

A low-carbohydrate lifestyle is an effective treatment option to prevent chronic diseases.

Gastric acid suppressants may increase risk of recurrent <i>Clostridium difficile</i> infection

Gastric acid suppressants may increase risk of recurrent Clostridium difficile infection

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A meta-analysis suggests that patients who take gastric acid suppressants may have a higher risk for recurrent CDI.

PCV10 vaccine decreases pneumonia rate in children

PCV10 vaccine decreases pneumonia rate in children

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PCV10 decreases rate of pneumonia among vaccine-eligible children and older, unvaccinated children.

High cardiac troponin levels may predict mortality in community-acquired pneumonia

High cardiac troponin levels may predict mortality in community-acquired pneumonia

Elevated cardiac troponin T is also strongly prognostic of cardiac mortality observed in association with community-acquired pneumonia.

Antibiotic prescribing in primary care varies for community-acquired pneumonia

Antibiotic prescribing in primary care varies for community-acquired pneumonia

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Factors that contribute to antibiotic choice for CAP include patient age, previous antibiotic receipt, and private insurance.

Pneumococcal conjugate vaccine reduces <i>Streptococcus pneumoniae</i> bacteremia

Pneumococcal conjugate vaccine reduces Streptococcus pneumoniae bacteremia

Researchers observed a 95.3% reduction of Streptococcus pneumoniae bacteremia after implementation of routine immunization with the pneumococcal conjugate vaccine.

Septic shock: early, goal-directed therapy versus usual care

Septic shock: early, goal-directed therapy versus usual care

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Early, goal-directed therapy did not result in better outcomes for mortality for patients with septic shock.

Adolescents not seeking STD services due to confidentiality issues

Adolescents not seeking STD services due to confidentiality issues

Adolescents might not seek care or might delay seeking care for STD services because of concerns about confidentiality, including fears that their parents might find out.

HPV educational session may boost vaccination rates in high school students

HPV educational session may boost vaccination rates in high school students

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The students improved their basic knowledge of HPV and understood the benefits of the HPV vaccine.

Inhaled corticosteroids not tied to pneumonia in children with asthma

Inhaled corticosteroids not tied to pneumonia in children with asthma

Results showed no link between inhaled corticosteroids and risk of pharyngitis, otitis media, or sinusitis.

More antimicrobial treatments needed in community-acquired pneumonia

More antimicrobial treatments needed in community-acquired pneumonia

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Findings from a US claims-based retrospective study call for more effective antimicrobial treatments for patients with community-acquired pneumonia.

CDC expands investigation into Seoul virus outbreak

CDC expands investigation into Seoul virus outbreak

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Symptoms of Seoul virus infection typically begin within 1 to 2 weeks after contact with infectious material and include fever, headache, and back pain.

Stroke risk increases after herpes zoster in patients with autoimmune disease

Stroke risk increases after herpes zoster in patients with autoimmune disease

Herpes zoster was linked to an increased stroke risk in first 90 days among patients with an autoimmune disease.

High-potency statins increase hospitalization for community-acquired pneumonia

High-potency statins increase hospitalization for community-acquired pneumonia

Higher-potency statins increased hospitalization for community-acquired pneumonia compared with lower-potency statins.

Pneumococcal vaccination reduces pneumonia risk in COPD patients

Pneumococcal vaccination reduces pneumonia risk in COPD patients

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Polyvalent pneumococcal vaccines offered protection against community-acquired pneumonia in COPD patients.

Pneumonia vaccine may not be effective in rheumatoid arthritis patients

Pneumonia vaccine may not be effective in rheumatoid arthritis patients

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The PPSV23 vaccine may not prevent pneumonia in patients with rheumatoid arthritis.

Sepsis and septic shock: new guidelines for clinical management

Sepsis and septic shock: new guidelines for clinical management

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Updated international guidelines for managing sepsis and septic shock have been released by the Society of Critical Care Medicine and European Society of Intensive Care Medicine.

Use of fluoroquinolones linked to <i>C. difficile</i> outbreak

Use of fluoroquinolones linked to C. difficile outbreak

A C. difficile epidemic was an unintended consequence of the intensive use of fluoroquinolones.

Pritelivir better for treating genital HSV-2 than valacyclovir

Pritelivir better for treating genital HSV-2 than valacyclovir

HSV shedding was detected in 2.4% of swabs during pritelivir treatment compared with 5.3% during valacyclovir treatment.

USPSTF recommends against routine serologic screening for genital herpes simplex virus

USPSTF recommends against routine serologic screening for genital herpes simplex virus

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The USPSTF has released a final recommendation against routine serologic screening for genital herpes simplex virus infection.

CDC: Influenza vaccine rate low this season

CDC: Influenza vaccine rate low this season

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Forty percent of people have reported receiving the flu vaccine thus far, including 37% of children.

Newborn screening identifies unknown cause of severe combined immunodeficiency

Newborn screening identifies unknown cause of severe combined immunodeficiency

The screening identified BCL11B as the previously unknown cause of human SCID.

Mortality rate from infectious diseases remains unchanged in the United States

Mortality rate from infectious diseases remains unchanged in the United States

The number of patients dying from infections has remained stable, but some disease threats have changed.

High-dose vitamin D may decrease acute respiratory infections in elderly

High-dose vitamin D may decrease acute respiratory infections in elderly

Vitamin D supplementation may be associated with reduced ARIs among long-term care facility residents.

Outbreak of Candida auris identified in the US

Outbreak of Candida auris identified in the US

The CDC requested that laboratories report cases and send patient samples to state and local health departments and the CDC.

More than half of US citizens have a chronic health condition

More than half of US citizens have a chronic health condition

Conditions such as chronic disease, mental illness, or substance abuse commonly overlap with each other and with poverty, which contributes to poor health.

The role of biofilms in chronic infections

The role of biofilms in chronic infections

Bacteria in contact with living tissues form layers that resist penetration by the immune system or antibiotics, but promising treatments abound.

CDC approves HPV vaccine in 2 doses for preteens

CDC approves HPV vaccine in 2 doses for preteens

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Children younger than 15 may be given 2 HPV vaccine doses instead of 3, and the shots should be spaced at least 6 months apart.

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