Unlike other antibiotics used to treat gonorrhea, zoliflodacin, a spiropyrimidinetrione antimicrobial agent, works by inhibiting DNA biosynthesis by arresting the cleaved covalent gyrase complex, thereby impeding bacterial growth.
Health officials aren't sure what causes acute flaccid myelitis (AFM), a rare but serious polio-like disease that has emerged in the United States.
HIV-exposed infants have high rates of congenital cCMV infection, and in utero HIV infection seems to be a major risk factor for cCMV.
HIV-infected Hispanics have an increased risk for human papillomavirus-related cancers than Hispanics in the general population.
The American Association for the Study of Liver Diseases (AASLD) and the Infectious Diseases Society of America (IDSA) released updates guidelines for treating hepatitis C infection.
The inappropriate use of antibiotics as prophylaxis and treatment in acute pancreatitis is common, highlighting the efforts required for antibiotic stewardship.
The burden of childhood and infant pneumonia can be effectively reduced through the use of the pneumococcal Haemophilus influenzae protein D conjugate vaccine.
An outbreak of flea-borne typhus in Los Angeles County has so far resulted in 57 cases, including 20 in Pasadena and 9 in downtown Los Angeles.
The approval of the expanded age range was based on data from a clinical trial which evaluated the efficacy of Gardasil (quadrivalent human papillomavirus recombinant vaccine) in 3253 women 27-45 years of age with a median duration of follow-up of 3.5 years post-dose 3.
In patients taking multiple antibiotics, proton pump inhibitors, or histamine receptor antagonists, the concurrent use of probiotics was associated with an increased incidence of Clostridium difficile infection
For patients with CAP, antibiotic regimens including a fluoroquinolone may reduce mortality risk by 1-2% compared to beta-lactams and cephalosporins alone.
A combination single tablet once-a-day regimen of doravirine/lamivudine/tenofovir disoproxil fumarate demonstrated non-inferiority and no significant adverse events when compared with continuation of established antiretroviral therapy in adults infected with HIV-1.
A documented β -lactam allergy was found in more than one-third of patients receiving broad-spectrum antibiotics, however, only 10% of patients were found to be truly allergic.
The use of a moderate to low susceptibility antibiotic to treat a urinary tract infection [UTI] may result in a 1.74-fold increase in the odds of an emergency department readmission within 30 days for another UTI.
Fidaxomicin demonstrated the strongest evidence for being the most effective treatment in providing a long-term cure for C difficile infection.
As of end of May 2018, 199 cases of salmonellosis identified that were linked to kratom consumption.
The United States has the seventh highest prevalence of Chagas infection in the Western hemisphere, with most cases seen among immigrants from Latin America.
Inverse association identified between NME rate and MMR vaccine coverage of kindergarteners.
The administration of PCV7 and PCV13 reduced the number of ambulatory visits for otitis media in pediatric patients.
Using state- and individual-level data from the 1995-2014 National Immunization Survey, the effect of a state's Universal Purchase adoption on vaccination rates was estimated.
Estimated annual incidence of viral meningitis is 2.73 per 100,000 UK adults.
The 2017-2018 influenza season in the United States (October 1, 2017-May 19, 2018) was a high-severity season.
Annual occasion is a good time for health care providers to encourage testing
The CDC has identified an increasing number of Shigella isolates that test within the susceptible range for the fluoroquinolone antibiotic ciprofloxacin.
ACX-362E is a targeted, narrow spectrum oral antibiotic that blocks the DNA replication process through inhibition of polymerase III, which has been shown to be bactericidal.
First documented case of Keystone infection in a human.
Although heads of state and governments have pledged to reduce premature mortality from noncommunicable diseases by one-third by 2030, many countries are not on track to achieve this goal.
Lyme neuroborreliosis diagnosis had no substantial effect on long-term survival, health, or educational/social functioning yet may be associated with an increased risk of hematologic and nonmelanoma skin cancers.
197 cases of illness linked to the E coli outbreak, 5 of which were fatal
The CDC recommends 2 doses of the MMR vaccine, which provides 97% protection against measles, prior to international travel.