April 2009 12 4 Issue of Clinical Advisor

April 2009 12 4 Issue of Clinical Advisor

Newsline

Trio of findings challenge Framingham tool

Three recent studies indicate that the Framingham risk score goes only so far as a predictor of cardiovascular problems.
 

Coffee every day may keep stroke away

Coffee consumption may modestly reduce the risk of stroke in women.
 

Prevention of prostate cancer

Men with no signs of prostate cancer should talk to their provider about taking a 5a-reductase inhibitor (5-ARI) for seven years to ward off the ...
 

Algorithm identifies risk for chronic kidney disease

A new algorithm helps predict which patients who have currently healthy kidneys are most likely to develop chronic kidney disease within a decade.
 

Widely used rheumatoid arthritis drugs may bring on shingles

Drugs that inhibit tumor necrosis factor-a (TNF-a) may significantly raise the risk of herpes zoster
 

RSV burden much heavier than expected

Respiratory syncytial virus is substantially underdiagnosed during pediatric office visits.
 

In the obese, weight loss reduces incontinence

Add incontinence relief to the list of benefits obese patients gain from losing weight.
 

Drug Updates from MPR

PPI for esophagitis and nonerosive GERD

Kapidex is designed to provide two separate releases of medication.
 

Topical treatment of acne vulgaris

Acanya contains benzoyl peroxide and the antibiotic clindamycin.
 

Cover Feature

Epilepsy in the elderly

Seizures in the elderly often mimic other conditions, such as transient ischemic attack or dementia. Don't be fooled into a misdiagnosis.
 

Clinical Feature

Early recognition of atypical celiac disease

Celiac disease doesn't look the way you might expect. A new position statement and technical review from the American Gastroenterological Association provide updated guidelines.
 

Dermatologic Look-Alikes

Nuchal plaques

Two cases of neck plaques—one that gets more pruritic at night and one that worsens after a visit to the barber.
 

Clinical Challenge

A college student's erratic behavior draws unwanted attention

The young woman had a personal history of drug use and a family history significant for schizophrenia and suicide.
 

Alternative Meds Update

Cocoa aids cardiovascular health

Consumed in moderation, the right type of chocolate may do more than satisfy a craving--it can also improve cerebral blood flow and lower blood pressure.
 

Dermatology Clinic

A tender finger papule, fever, and abdominal pain

A 54-year-old man complained of fevers and abdominal pain. Four days earlier, he had noted intense left upper-quadrant abdominal pain that was worse with inspiration ...
 

Pigmentation on the legs of a young female athlete

A 17-year-old female developed diffuse blue-gray pigmentation of both shins over a two-month period.
 

Evidence-Based Medicine

Low risk of colorectal cancer five years after negative screening

The risk of colorectal neoplasia is low five years after negative screening.
 

Risk of prostate or other cancers in men unaffected by selenium or vitamin E

Neither selenium nor vitamin E, alone or in combination, reduced the risk of prostate cancer or other cancers in men.
 

Pneumovax may not be effective

But Prevnar may decrease meningitis and pneumonia hospitalizations.
 

Perioperative beta blockers reduce rate of nonfatal MI

But increase stroke and may increase mortality
 

Stat Consult

Legal Advisor

Colorectal cancer misdiagnosed as hemorrhoids

A new mother presents with common postpartum symptoms. When should clinicians start considering more remote possibilities?
 

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