Menopause

Disorders in Pregnancy May Increase Risk for Hot Flashes During Menopause

Disorders in Pregnancy May Increase Risk for Hot Flashes During Menopause

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Hypertensive disorders of pregnancy and gestational diabetes may increase the risk for hot flashes during menopause.

Light Therapy Offers Nonpharmacologic Treatment for Perimenopausal Depression

Light Therapy Offers Nonpharmacologic Treatment for Perimenopausal Depression

Light treatments successfully corrected abnormal timing of melatonin circadian rhythms in perimenopausal women with depression and improved mood and sleep within 2 weeks.

Physical Activity as a Lifestyle Factor Influencing Early Menopause

Physical Activity as a Lifestyle Factor Influencing Early Menopause

Researchers concluded that physical activity was not associated with risk for early menopause.

Imvexxy Now Available in 4mcg Dosage Strength for Dyspareunia Due to Menopause

Imvexxy Now Available in 4mcg Dosage Strength for Dyspareunia Due to Menopause

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According to the Imvexxy prescribing information, women should generally be started at the 4mcg dosage strength with dosage adjustment guided by clinical response.

Guidelines for Managing Perimenopausal Depression Now Available

Guidelines for Managing Perimenopausal Depression Now Available

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The 5 topics addressed by the 11-member expert panel include epidemiology, clinical presentation, therapeutic effects of antidepressants, effects of hormone therapy, and the effectiveness of other therapies (eg, psychotherapy, exercise, natural health products).

Breastfeeding Linked to Lower Risk of Stroke Post-Menopause

Breastfeeding Linked to Lower Risk of Stroke Post-Menopause

Stroke risk 19% lower with breastfeeding for 1 to 6 months; stronger link for longer duration.

Genitourinary Syndrome of Menopause:  A Consensus Statement From the ISSWSH

Genitourinary Syndrome of Menopause: A Consensus Statement From the ISSWSH

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The International Society for the Study of Women's Sexual Health convened an expert consensus panel to discuss the use of androgens in the management of genitourinary syndrome of menopause.

Characteristics of Menstrual Cycle Associated With Early Natural Menopause

Characteristics of Menstrual Cycle Associated With Early Natural Menopause

Investigators examined the relationship between menstrual cycle characteristics in adolescence and early adulthood and the risk for early natural menopause.

No Impact on Carotid Artery Intima-Media Thickness Following Cessation of Menopausal Hormone Therapy

No Impact on Carotid Artery Intima-Media Thickness Following Cessation of Menopausal Hormone Therapy

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A follow-up study from KEEPS found that cessation of menopausal hormone therapy did not change the expected trajectory of carotid artery intima-media thickness over a 3-year period.

Ectopic Lipid Deposition and Insulin Resistance Higher in Postmenopausal Women

Ectopic Lipid Deposition and Insulin Resistance Higher in Postmenopausal Women

The insulin sensitivity in post- and premenopausal women along with lipid deposition in the liver and skeletal muscle was examined.

Menopause Transition Often Prompts Changes in Migraine Pattern, Characteristics

Menopause Transition Often Prompts Changes in Migraine Pattern, Characteristics

This retrospective study sought to assess migraine patterns in 69 menopausal women between ages 40 and 60 who were treated at Partners Healthcare Hospitals for concurrent migraine headache.

Reproductive Dysfunction Risk in Women Taking Long-Term Opioids for Musculoskeletal Pain

Reproductive Dysfunction Risk in Women Taking Long-Term Opioids for Musculoskeletal Pain

Women prescribed long- vs short-term opioids for chronic musculoskeletal pain may be at increased risk for menopause and abnormal menstruation.

Menopausal Hormone Therapy Slows Cognitive Decline in Postmenopausal Women

Menopausal Hormone Therapy Slows Cognitive Decline in Postmenopausal Women

Hormone therapy in postmenopausal women with mild cognitive impairment was examined.

No Additional Benefits With Vaginal Estradiol Tablets, Moisturizers for Postmenopausal Vulvovaginal Symptoms

No Additional Benefits With Vaginal Estradiol Tablets, Moisturizers for Postmenopausal Vulvovaginal Symptoms

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Prescribed vaginal estradiol tablets and over-the-counter vaginal moisturizers may not be more effective than placebos for postmenopausal vulvovaginal symptoms.

Nutraceuticals Containing Equol May Be Effective for Postmenopausal Symptoms

Nutraceuticals Containing Equol May Be Effective for Postmenopausal Symptoms

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Equol-containing nutraceuticals may be beneficial for postmenopausal women with vaginal symptoms.

Imvexxy Approved for Moderate to Severe Dyspareunia Due to Menopause

Imvexxy Approved for Moderate to Severe Dyspareunia Due to Menopause

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The FDA approval was supported by findings from a Phase 3, randomized, double-blind, placebo-controlled study that evaluated Imvexxy (4mcg and 10mcg) vs placebo from baseline to week 12.

Fatigue, muscle aches more common in women with HIV than men

Fatigue, muscle aches more common in women with HIV than men

The two most prevalent HIV symptoms, fatigue and muscle aches, are more common in women than men and can worsen with menopause.

Managing acute UTIs in postmenopausal women

Managing acute UTIs in postmenopausal women

UTIs present clinically as dysuria, with symptoms of frequent and urgent urination secondary to irritation of the urethral and bladder mucosa.

BMI may not indicate obesity in postmenopausal women

BMI may not indicate obesity in postmenopausal women

Body mass index BMI at a cut-point of 30 kg/m2 may not be an appropriate indicator of obesity in postmenopausal women.

Menopausal hormone therapy for chronic conditions: USPSTF's final recommendation

Menopausal hormone therapy for chronic conditions: USPSTF's final recommendation

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The USPSTF has updated its recommendations on the use of menopausal hormone therapy for the primary prevention of chronic conditions.

Underweight women have high risk of early menopause

Underweight women have high risk of early menopause

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Early menopause risk is highest in weight-cycling and severely underweight women.

Hormone replacement therapy for menopause not associated with increased mortality risk

Hormone replacement therapy for menopause not associated with increased mortality risk

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The researchers found no long-term increase in either all-cause or cause-specific mortality among women who received hormone therapy for up to 5.6 years or 7.2 years, depending on the type of therapy.

Earlier menopause may increase risk of type 2 diabetes

Earlier menopause may increase risk of type 2 diabetes

Women who experienced early menopause were 2.4 times more likely to develop diabetes.

FDA approves new drug for postmenopausal pain during sex

FDA approves new drug for postmenopausal pain during sex

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Intrarosa provides an additional treatment option for women with dyspareunia caused by vulvar and vaginal atrophy.

Sex hormone-binding globulin and estradiol associated with type 2 diabetes in women

Sex hormone-binding globulin and estradiol associated with type 2 diabetes in women

Women may have a higher risk of type 2 diabetes with low levels of sex hormone-binding globulin and high levels of total estradiol.

Nighttime hot flashes may be linked to mild depression

Nighttime hot flashes may be linked to mild depression

Women who experience more nighttime hot flashes are more likely to experience worsening mood during menopause.

Menopausal transition linked to rapid increase in metabolic syndrome severity

Menopausal transition linked to rapid increase in metabolic syndrome severity

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The American Heart Association found that during menopausal transition, women have a rapid increase in metabolic syndrome severity.

Vitamin D supplementation does not improve functional outcomes in postmenopausal women

Vitamin D supplementation does not improve functional outcomes in postmenopausal women

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Vitamin D deficiency is especially prevalent in postmenopausal women, and recommendations from current guidelines are inconsistent regarding vitamin D use.

Smoking linked to infertility, early menopause

Smoking linked to infertility, early menopause

Researchers confirmed increased risks for infertility and natural menopause before age 50 in women who are either active smokers or regularly exposed to secondhand smoke.

New treatment guidelines for menopause emphasize individualized care

New treatment guidelines for menopause emphasize individualized care

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New guidelines issued by the Endocrine Society and published in the Journal of Clinical Endocrinology and Metabolism suggest that clinicians should provide patients with individualized menopause treatments.

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