Generic Name and Formulations:
Atovaquone 750mg/5mL; susp; citrus flavor.
Indications for MEPRON:
Treatment of mild to moderate Pneumocystis carinii pneumonia (PCP) in patients intolerant to trimethoprim/sulfamethoxazole (TMP/SMX). Prevention of PCP in patients intolerant to TMP/SMX.
Take with food. Treatment: 750mg twice daily for 21 days. Prophylaxis: 1500mg once daily.
See full labeling.
GI disorders or inability to take with food. Monitor in severe hepatic impairment. Elderly. Pregnancy (Cat.C). Nursing mothers.
Antagonized by rifampin. Caution with other highly protein-bound drugs.
Rash, headache, GI upset, dyspnea, cough, rhinitis, infection, fever, elevated liver enzymes, insomnia, asthenia, oral moniliasis, pruritus, sinusitis, anorexia, depression, myalgia, pancreatitis, thrombocytopenia, allergic reactions.