For patients with chronic obstructive pulmonary disease and comorbid posttraumatic stress disorder, long-term benzodiazepine use is not associated with mortality, but there is an association for short-term benzodiazepine use.
The quality of patient monitoring may improve if the clinical practice guidelines are improved, as many healthcare professionals use the guidelines in their monitoring of patients taking lithium.
Screening of adult patients with significant depressive symptoms is often inadequate in the primary care setting, especially among those with hazardous alcohol consumption.
These data support the clinical use of combinatorial pharmacogenetics for patients with major depressive disorder.
Older adults with bipolar disorder may benefit from a detailed assessment of the use of substances.
A 25-item true and false questionnaire was used to assess knowledge of bipolar disorder.
Personal recovery improved more rapidly for participants in the anxiety in bipolar disorder intervention, but not social and personal functioning.
Investigators determined that titrating sertraline to 100 mg/day vs 50 mg/day for initial antidepressant therapy for a new MDD episode has no added benefit and increases cost.
Transcranial magnetic stimulation (TMS) uses magnetic fields to stimulate nerve cells in the brain.
Findings seen across spectrum of care -- outpatient, emergency department, inpatient.
Does Bipolar I Disorder Effect the Course of Conduct/Antisocial Personality Disorders in Adolescents?August 13, 2018
Adolescents with bipolar I disorder whose symptoms are in remission are significantly less likely to experience conduct disorder or antisocial personality disorder.
There is no distinct cut off for the Functional Assessment Short Test between none, mind, moderate, and severe functional impairment.
Perseris, an atypical antipsychotic, has an extended-release delivery system that releases sustained levels of risperidone over 1 month.
Maternal lithium use in the first trimester of pregnancy may increase the risk for infant malformations.
Depressed mood more common in young pregnant women today than in their mothers' generation.
Differences Between Cyclothymic Disorder and Unspecified Bipolar Disorder in Youth May Indicate Course of DisorderJuly 16, 2018
Investigators sought to determine the differences between youth with cyclothymic disorder and bipolar disorder not otherwise specified.
Patients receiving treatment with antipsychotic agents would benefit from screening for tardive dyskinesia as these repetitive movements can negatively affect quality of life.
Repeated assessments improved the patients' ability to assess their own situation and the case workers' understanding of the patients' situations.
These findings are in line with previous research, which suggested that abuse and neglect in childhood have different effects on the brain.
As antipsychotic medications are vital to the effective management of severe psychiatric disorders, investigators sought to examine reasons for medication nonadherence in patients with schizophrenia, bipolar disorders, and other psychotic disorders.
Schizophrenia, Major Depressive Disorder, Bipolar Disorder Linked With Abnormal Functional ConnectivityJune 22, 2018
Local functional connectivity may serve as neuroimaging marker to investigate the human brain connectome.
A meta-analysis of 18 studies examining the association of prenatal antidepressant exposure with motor development in children showed a small overall effect of worse motor development outcomes among children exposed to antidepressants in pregnancy.
In this cross-sectional study, the use of medications with depression as an adverse effect was associated with a higher prevalence of depression while a similar association was not observed for medications without depression as a possible side effect.
Prevalence of depression higher for adults reporting use of multiple meds with depression as side effect
These data may lead to a more nuanced understanding of bipolar disorder and to a better definition of the effectiveness of interventions directed at treating both personality disorders and bipolar disorder.
Results were slightly attenuated but remained mostly significant with adjustment for prognostic factors
Increased implementation of integrated primary care could help to improve the availability of psychological treatment for this patient population.
Primary care providers should screen for depression and other health-related risks associated with the use of social media by adolescents.
The broad use of antidepressants among the general population may be linked to weight gain.
As this and previous research on dose increase strategies have produced inconsistent findings, the researchers recommended clinicians consider other responses to antidepressant treatment failure, at least for selective serotonin reuptake inhibitors.