Mood Disorders

Lithium not linked to increased cancer risk in patients with bipolar disorder

Lithium not linked to increased cancer risk in patients with bipolar disorder

By

No difference was observed in risk of overall cancer in patients with bipolar disorder who use lithium, compared with the general population.

Off-label antidepressant prescriptions not supported by strong scientific evidence

Off-label antidepressant prescriptions not supported by strong scientific evidence

By

For many off-label indications, the prescribed drug is often not supported by strong evidence for the respective indication.

Ketamine may benefit certain patients for treatment of mood disorders

Ketamine may benefit certain patients for treatment of mood disorders

Appropriate patient section for ketamine treatment should include diagnostic considerations and assessment of other medical, psychological, and social factors.

Patients with a mental health disorder more likely to refuse pharmacotherapy

Patients with a mental health disorder more likely to refuse pharmacotherapy

Differences in refusal rates for pharmacotherapy and psychotherapy were particularly evident for depressive disorders, panic disorder, and social anxiety disorder.

Postpartum depression incidence declining

Postpartum depression incidence declining

By

Reducing postpartum depression involves universal screening and appropriate referral and treatment by clinicians.

Schizophrenia: a clinical overview

Schizophrenia: a clinical overview

By

A better understanding of this complicated condition is key to helping patients reduce symptoms, maximize quality of life, and improve adaptive functioning skills.

Prestroke psychosocial factors linked to poststroke depression risk in women

Prestroke psychosocial factors linked to poststroke depression risk in women

By

Women with a good recovery after stroke and a moderate level of optimism had a 0.40‐fold reduction in the odds of developing new-onset poststroke depression.

Atypical antipsychotic therapy with mood stabilizers effective after bipolar episode

Atypical antipsychotic therapy with mood stabilizers effective after bipolar episode

By

Atypical antipsychotic adjunctive therapy and mood stabilizers may be a more effective treatment than mood stabilizer monotherapy.

Anxiety and depression may have predictive role in cancer mortality

Anxiety and depression may have predictive role in cancer mortality

By

Researchers measured vital status records to ascertain death from 16 site-specific malignancies.

Managing bipolar disorder: pharmacologic options for treatment

Managing bipolar disorder: pharmacologic options for treatment

Lithium has been the mainstay of treatment for decades, but several other classes of medication have recently been used with varying degrees of success.

Lithium side effects and management strategies

Lithium side effects and management strategies

By

The declining rates for lithium use are linked to the burden of side effects and toxicity associated with the drug.

Mortality risk increased in type 2 diabetes with depression or anxiety

Mortality risk increased in type 2 diabetes with depression or anxiety

Men with diabetes, but not women, had excess mortality risk associated with depression and anxiety.

Depression literacy higher in women and linked to medication adherence

Depression literacy higher in women and linked to medication adherence

By

Some aspects of depression literacy were lower among patients with depression.

Panic disorder may increase risk of depression treatment side effects

Panic disorder may increase risk of depression treatment side effects

Comorbid panic disorder was linked to increased likelihood of side effects during treatment for depression.

Depression rate high in patients with mild cognitive impairment

Depression rate high in patients with mild cognitive impairment

By

About one-third of patients with MCI are also diagnosed with depression.

Smartphone questionnaire effective for monitoring mood instability

Smartphone questionnaire effective for monitoring mood instability

By

The Mood Zoom questionnaire rates anxiety, elation, sadness, anger, irritability, and energy on a 7-point scale.

Hyperhidrosis linked to increase in anxiety and depression

Hyperhidrosis linked to increase in anxiety and depression

The researchers found that the prevalence of anxiety was 21.3% and depression 27.2% in patients with HH.

End of daylight saving time may increase depression risk

End of daylight saving time may increase depression risk

By

The transition to standard time is likely to be associated with a negative psychological effect.

High cognitive reserve results in better neurocognitive performance in bipolar disorder

High cognitive reserve results in better neurocognitive performance in bipolar disorder

By

Cognitive reserve in bipolar patients gives a possible explanation for the differences seen among patients in their ability to perform in neurocognitive tests.

Memantine plus sertraline effective for major depressive disorder

Memantine plus sertraline effective for major depressive disorder

Patients taking memantine plus sertraline had significantly greater improvement and greater response rate.

Pharmacogenetic analysis benefits patients unresponsive to clomipramine

Pharmacogenetic analysis benefits patients unresponsive to clomipramine

Therapeutic drug monitoring and pharmacogenetic analyses may be useful in the optimization of clomipramine in nonresponders.

Depression may worsen outcomes in patients with chronic stable angina

Depression may worsen outcomes in patients with chronic stable angina

Depression can occur in approximately 1 in 5 patients who have chronic stable angina.

Cohort effect shows earlier and stronger effects of bipolar disorder

Cohort effect shows earlier and stronger effects of bipolar disorder

By

Researchers observe a cohort effect for earlier age at onset of bipolar disorder. Bipolar disorder is also more common in patients with a family history of unipolar depression and bipolar disorder.

Bipolar disorder treatment more effective in earlier stages

Bipolar disorder treatment more effective in earlier stages

By

Treatment initiated in the early stages of bipolar disorder is more effective than treatment in later stages.

Many adults with depression are not receiving treatment

Many adults with depression are not receiving treatment

Survey results revealed that only 28.7% of patients with depression receive any treatment.

Sertraline may prevent depressive disorders after traumatic brain injury

Sertraline may prevent depressive disorders after traumatic brain injury

The number needed to treat was 5.9 for sertraline vs placebo to prevent depression after a traumatic brain injury.

Acetaminophen use during pregnancy linked to higher risk of childhood behavioral problems

Acetaminophen use during pregnancy linked to higher risk of childhood behavioral problems

By

Children exposed to acetaminophen prenatally had an increased risk of multiple behavioral difficulties.

Depression limits adherence to COPD maintenance medications

Depression limits adherence to COPD maintenance medications

Older adults with depression are less likely to adhere to COPD maintenance medications regimens.

Suicide prevention: restricting access to lethal means is effective

Suicide prevention: restricting access to lethal means is effective

By

While many suicide prevention techniques are effective, others have not been proven to be beneficial.

Most antidepressants may be ineffective for children, adolescents

Most antidepressants may be ineffective for children, adolescents

By

For children and teens diagnosed with depression, the benefits of the most commonly prescribed antidepressants may not outweigh the risks.

Sign Up for Free e-newsletters