Mood Disorders

Smartphone questionnaire effective for monitoring mood instability

Smartphone questionnaire effective for monitoring mood instability

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The Mood Zoom questionnaire rates anxiety, elation, sadness, anger, irritability, and energy on a 7-point scale.

Hyperhidrosis linked to increase in anxiety and depression

Hyperhidrosis linked to increase in anxiety and depression

The researchers found that the prevalence of anxiety was 21.3% and depression 27.2% in patients with HH.

End of daylight saving time may increase depression risk

End of daylight saving time may increase depression risk

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The transition to standard time is likely to be associated with a negative psychological effect.

High cognitive reserve results in better neurocognitive performance in bipolar disorder

High cognitive reserve results in better neurocognitive performance in bipolar disorder

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Cognitive reserve in bipolar patients gives a possible explanation for the differences seen among patients in their ability to perform in neurocognitive tests.

Memantine plus sertraline effective for major depressive disorder

Memantine plus sertraline effective for major depressive disorder

Patients taking memantine plus sertraline had significantly greater improvement and greater response rate.

Pharmacogenetic analysis benefits patients unresponsive to clomipramine

Pharmacogenetic analysis benefits patients unresponsive to clomipramine

Therapeutic drug monitoring and pharmacogenetic analyses may be useful in the optimization of clomipramine in nonresponders.

Depression may worsen outcomes in patients with chronic stable angina

Depression may worsen outcomes in patients with chronic stable angina

Depression can occur in approximately 1 in 5 patients who have chronic stable angina.

Cohort effect shows earlier and stronger effects of bipolar disorder

Cohort effect shows earlier and stronger effects of bipolar disorder

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Researchers observe a cohort effect for earlier age at onset of bipolar disorder. Bipolar disorder is also more common in patients with a family history of unipolar depression and bipolar disorder.

Bipolar disorder treatment more effective in earlier stages

Bipolar disorder treatment more effective in earlier stages

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Treatment initiated in the early stages of bipolar disorder is more effective than treatment in later stages.

Many adults with depression are not receiving treatment

Many adults with depression are not receiving treatment

Survey results revealed that only 28.7% of patients with depression receive any treatment.

Sertraline may prevent depressive disorders after traumatic brain injury

Sertraline may prevent depressive disorders after traumatic brain injury

The number needed to treat was 5.9 for sertraline vs placebo to prevent depression after a traumatic brain injury.

Acetaminophen use during pregnancy linked to higher risk of childhood behavioral problems

Acetaminophen use during pregnancy linked to higher risk of childhood behavioral problems

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Children exposed to acetaminophen prenatally had an increased risk of multiple behavioral difficulties.

Depression limits adherence to COPD maintenance medications

Depression limits adherence to COPD maintenance medications

Older adults with depression are less likely to adhere to COPD maintenance medications regimens.

Suicide prevention: restricting access to lethal means is effective

Suicide prevention: restricting access to lethal means is effective

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While many suicide prevention techniques are effective, others have not been proven to be beneficial.

Most antidepressants may be ineffective for children, adolescents

Most antidepressants may be ineffective for children, adolescents

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For children and teens diagnosed with depression, the benefits of the most commonly prescribed antidepressants may not outweigh the risks.

Depression is underdiagnosed in adolescents with diabetes

Depression is underdiagnosed in adolescents with diabetes

In adolescents with type 1 or type 2 diabetes, the rates of diagnosed depression are lower than the number of patients reporting depressive symptoms.

Efficacy of psychotherapy overestimated for depression

Efficacy of psychotherapy overestimated for depression

An analysis of 55 studies found that medical literature overestimates the efficacy of psychotherapy for depression by about 10%.

Combination of antidepressants and NSAIDs may increase intracranial hemorrhage risk

Combination of antidepressants and NSAIDs may increase intracranial hemorrhage risk

People who started taking an antidepressant while taking NSAIDs had increased risk of intracranial hemorrhage.

New drug approved for schizophrenia, depression

New drug approved for schizophrenia, depression

Rexulti is indicated for treating schizophrenia and for major depression after first-line treatments fail.

Consider alternatives to drug therapy for geriatric depression


Consider alternatives to drug therapy for geriatric depression


Geriatric patients who are not responding well to antidepressants may benefit from a combination of pharmacotherapy and psychotherapy.

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