Neurology

Exercise May Delay Symptoms of Alzheimer's in Those at Risk

Exercise May Delay Symptoms of Alzheimer's in Those at Risk

Findings among individuals with a genetic mutation known to cause Alzheimer's.

Change in Dietary Patterns Over 5 Years in Early Multiple Sclerosis

Change in Dietary Patterns Over 5 Years in Early Multiple Sclerosis

Researchers analyze the dietary habits of 260 patients in the early stages of multiple sclerosis from baseline to 5 years after initial onset of symptoms.

Hospitals Using Get With the Guidelines-Stroke Program Offer Better Quality Care in Ischemic Stroke

Hospitals Using Get With the Guidelines-Stroke Program Offer Better Quality Care in Ischemic Stroke

The Get With the Guidelines-Stroke program includes measures such as neurologist assessment, rehabilitation evaluation, and education on stroke risk factors.

Acetaminophen Can Reduce Recurrence of Febrile Seizures

Acetaminophen Can Reduce Recurrence of Febrile Seizures

For children, infants with febrile seizure, recurrence down with acetaminophen vs no antipyretic.

New AAN Guidelines for the Management of Disorders of Consciousness

New AAN Guidelines for the Management of Disorders of Consciousness

The new guidelines place a substantial emphasis on the importance of introducing high-quality rehabilitation early in these patients.

Fycompa Approved for Younger Epilepsy Patients With Partial-Onset Seizures

Fycompa Approved for Younger Epilepsy Patients With Partial-Onset Seizures

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Safety data for Fycompa was consistent with the safety profile in adult populations without the need for weight-based dosing.

NDA Submitted for Valtoco Nasal Spray to Treat Acute Repetitive Seizures

NDA Submitted for Valtoco Nasal Spray to Treat Acute Repetitive Seizures

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The Company states that the NDA is supported by robust clinical trial data, including patients studies where more than 1600 seizures were treated with Valtoco nasal spray.

Outcomes After Seizure Recurrence Upon AED Withdrawal Following Temporal Lobectomy

Outcomes After Seizure Recurrence Upon AED Withdrawal Following Temporal Lobectomy

Recurrence of seizures was reported in 28.2% of patients who attempted withdrawal.

Late-Onset Epilepsy Linked to <i>APOE</i> ε4, Smoking, Diabetes

Late-Onset Epilepsy Linked to APOE ε4, Smoking, Diabetes

The risk for late-onset epilepsy was lower in patients with higher physical activity levels and moderate alcohol intake.

Folic Acid Supplementation May Protect Against Language Delay in AED-Exposed Children

Folic Acid Supplementation May Protect Against Language Delay in AED-Exposed Children

The odds of language delay were lower at 18 months and 36 months in children exposed to AEDs in utero whose mothers took folic acid.

Effects of Parental Decision Aids on ED CT Rates Among Children at Risk for TBI

Effects of Parental Decision Aids on ED CT Rates Among Children at Risk for TBI

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Emergency department computed tomography rates for children with minor head trauma were not affected by parent decision aid use.

Case Study: Worsening Headache After Giving Birth

Case Study: Worsening Headache After Giving Birth

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A 32-year-old woman presents to the emergency department with gradually worsening generalized headache 8 days after giving birth to her second child.

Recreational Screen Time, Sleep Duration Linked to Cognitive Development in Children

Recreational Screen Time, Sleep Duration Linked to Cognitive Development in Children

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More than 2 hours of recreational screen time was found to be associated with cognitive decline in children.

Prevalence of Alzheimer's, Related Dementia Set to Double

Prevalence of Alzheimer's, Related Dementia Set to Double

Alzheimer's disease and related dementias burden is expected to increase to 3.3% in 2060.

Smoking Promotes Disease Progression in Multiple Sclerosis

Smoking Promotes Disease Progression in Multiple Sclerosis

Investigators examined the effects of smoking on respiratory symptoms and functional levels in patients with multiple sclerosis.

Age, Sex, <i>APOE</i> Genotype Identify Alzheimer's, Dementia Risk

Age, Sex, APOE Genotype Identify Alzheimer's, Dementia Risk

Three factors help identify absolute 10-year risk of Alzheimer's disease, all dementia for different groups.

Brivaracetam Effective for Reducing Seizures in Patients with Epileptic Encephalopathies

Brivaracetam Effective for Reducing Seizures in Patients with Epileptic Encephalopathies

Although 2 patients experienced an increase in seizure frequency, the remaining patients did not experience a change in frequency.

Many RA Patients' Pain Related to Central Nervous System

Many RA Patients' Pain Related to Central Nervous System

MRIs show rheumatoid arthritis patients have neurobiologic features observed in fibromyalgia.

New Guideline for Pediatric Mild Traumatic Brain Injury Diagnosis, Management

New Guideline for Pediatric Mild Traumatic Brain Injury Diagnosis, Management

Gradually increasing academic pursuits requires careful planning among the medical, school, and family units to enable prompt return and avoidance of prolonging school absence.

X-Rays, Blood Tests Not Advised for Children's Concussions

X-Rays, Blood Tests Not Advised for Children's Concussions

CT scans may be warranted in the case of vomiting, unconsciousness, and severe, worsening headaches.

Last 20 Years Saw Increase in Prevalence of ADHD in Children

Last 20 Years Saw Increase in Prevalence of ADHD in Children

Significant increases in prevalence in subgroups by age, sex, race/ethnicity, income, geographic region.

In Stroke Survivors, Cost-Related Non-Adherence Down After ACA

In Stroke Survivors, Cost-Related Non-Adherence Down After ACA

Among adult survivors of stroke, Medicaid increased, non-adherence decreased after ACA implementation.

Raising Awareness of Pseudobulbar Affect: Knowing the Signs, Symptoms, and Treatment for Patients With Uncontrollable Laughing or Crying

Raising Awareness of Pseudobulbar Affect: Knowing the Signs, Symptoms, and Treatment for Patients With Uncontrollable Laughing or Crying

Pseudobulbar affect is a significant national health issue in the United States, with approximately 2 million individuals affected.

Sensor Array May Detect De Novo Parkinson Disease in Breath

Sensor Array May Detect De Novo Parkinson Disease in Breath

Sensitivity, specificity, accuracy values of 79, 84, and 81% for detecting PD from controls.

Treatment of New-Onset Epilepsy: AAN, AES Update Practice Guidelines

Treatment of New-Onset Epilepsy: AAN, AES Update Practice Guidelines

An expert subcommittee was formed consisting of members of the AAN and AES to update the 2004 evidence-based guidelines on epilepsy treatment with AEDs.

TBI Linked to Increased Suicide Risk

TBI Linked to Increased Suicide Risk

Increased suicide risk with one, two, and three or more medical contacts for traumatic brain injury.

Traumatic brain injury associated with higher rate of suicide

In this retrospective study, Traumatic Brain Injury (TBI) was associated with a doubling in deaths by suicide, especially within the 6 months post-TBI.

Both Abstinence and High Alcohol Use Linked to Dementia

Both Abstinence and High Alcohol Use Linked to Dementia

Increased dementia risk for those with abstinence or with drinking 14 units alcohol/week in midlife.

Cognitive Impairment Profiles Differ Between Parkinson's, Alzheimer's

Cognitive Impairment Profiles Differ Between Parkinson's, Alzheimer's

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As the neurodegenerative processes of Alzheimer disease and Parkinson disease are different, early cognitive impairment also present differently in these diseases.

New Clinical Guideline for Evaluating Alzheimer's, Related Dementias

New Clinical Guideline for Evaluating Alzheimer's, Related Dementias

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Currently, there are no US consensus on best clinical practice guidelines that incorporate multispecialty recommendations for evaluating cognitive impairment that are thought to be due to Alzheimer's disease and Related Dementias (ADRD) for use by physicians and nurse practitioners.

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