An analysis of population data on cancer incidence, survival, and mortality revealed that early interventions and improvements to treatments contributed to a 26% decline in cancer deaths from 1991 to 2015.
First-line chemotherapy in combination with bevacizumab, compared with chemotherapy alone, may benefit patients with ovarian cancer and elevated neutrophil-to-lymphocyte ratios.
No significant difference was identified in combination CA125/CEA ratio vs CEA alone in distinguishing ovarian neoplasms from ovarian metastases.
Study patients who received Avastin plus chemotherapy followed by Avastin alone, had a greater median PFS vs patients who received chemotherapy alone (18.2 months vs 12 months; hazard ratio [HR] 0.62, 95% CI, 0.52-0.75; P<.0001).
Mirvetuximuab soravtansine uses a humanized FRα-binding antibody to target antibody-drug conjugates specifically to FRα-expressing cancer cells and a potent anti-tumor agent, DM4, to kill the targeted cancer cells.
Standardized definition, guidance on estimation may facilitate understanding of overdiagnosis.
Social media is an ideal platform to reach teenagers and young adults to encourage sun safety.
Investigators report results from the MONALEESA-7 trial, which assessed ribociclib plus endocrine therapy in premenopausal women with advanced breast cancer.
The percentage of NPs who order the mt-sDNA test for colorectal cancer screening has increased significantly since the test became available in 2014.
Percutaneous ablation compared with partial, radical nephrectomy for 4,310 patients aged 66 years
In women, risk declines as levels increase up to 100 nmol/L, but association in men not significant
Regardless of age, favorable survival conferred by an HPV-positive tumor status
Increased risk of subsequent diabetes independent of traditional diabetes risk factors
From 2006 and 2016, smallest increase seen in high Sociodemographic Index countries.
A prophylactic, graded, extended infusion of carboplatin, compared with a shorter, standard infusion, is not associated with a reduced rate of HSRs in women with recurrent ovarian cancer.
In year 1, 13% did not undergo MRI or mammography; up to 19% by year 5.
Average-risk adults aged 45 should undergo high-sensitivity stool-based test, structural exam
In a case study, olaparib was found to induce folate deficiency in most patients with relapsed ovarian cancer. Researchers discuss the significance of this adverse effect and how it was managed.
Age at diagnosis, sex, BMI, and thyroid-stimulating hormone suppression therapy affect CVD risk
Prediction tool may help physicians better personalize screening discussions with patients.
The American College of Cardiology, along with several other cardiology societies, have updated guidelines on best practices for improving safety when using ionizing radiation during cardiovascular imaging.
Findings for men with intermediate- and high-risk prostate cancer
Crossover in sex-specific rates among US non-Hispanic whites born since 1965
Grip strength is strongly and inversely associated with all-cause mortality and incidence of and mortality from cardiovascular disease, respiratory disease, COPD, all cancer, and subtypes of cancer, with associations being modestly stronger in the younger age groups.
Risk not increased for non-advanced adenoma found on colonoscopy following flex sigmoidoscopy
AAPA and SDPA respond to a recent article published in JAMA Dermatology.
But majority of oncologists don't feel knowledgeable enough to make these recommendations
For patients with platinum-sensitive recurrent ovarian cancer, trabectedin plus PLD may be beneficial.
Mice treated with 2-94 had few or no signs of lymphopenia or neutropenia, common adverse events associated with palbociclib.
The researchers enrolled 25 platinum-pretreated, immunotherapy-naïve patients with recurrent advanced epithelial ovarian cancer (EOC) for the trial.