Oncology

Progress Report in Cancer Control: How Are We Doing?

Progress Report in Cancer Control: How Are We Doing?

An analysis of population data on cancer incidence, survival, and mortality revealed that early interventions and improvements to treatments contributed to a 26% decline in cancer deaths from 1991 to 2015.

Chemotherapy With Bevacizumab May Improve Some Ovarian Cancer Outcomes, Worsen Others

Chemotherapy With Bevacizumab May Improve Some Ovarian Cancer Outcomes, Worsen Others

By

First-line chemotherapy in combination with bevacizumab, compared with chemotherapy alone, may benefit patients with ovarian cancer and elevated neutrophil-to-lymphocyte ratios.

No Difference in CEA vs CA125/CEA Ratio for Identifying Ovarian Masses

No Difference in CEA vs CA125/CEA Ratio for Identifying Ovarian Masses

By

No significant difference was identified in combination CA125/CEA ratio vs CEA alone in distinguishing ovarian neoplasms from ovarian metastases.

Avastin Plus ChemoTx Approved for Advanced Ovarian Cancer After Resection

Avastin Plus ChemoTx Approved for Advanced Ovarian Cancer After Resection

By

Study patients who received Avastin plus chemotherapy followed by Avastin alone, had a greater median PFS vs patients who received chemotherapy alone (18.2 months vs 12 months; hazard ratio [HR] 0.62, 95% CI, 0.52-0.75; P<.0001).

Mirvetuximab Gets Fast Track Status for Platinum-Resistant Ovarian Cancer

Mirvetuximab Gets Fast Track Status for Platinum-Resistant Ovarian Cancer

By

Mirvetuximuab soravtansine uses a humanized FRα-binding antibody to target antibody-drug conjugates specifically to FRα-expressing cancer cells and a potent anti-tumor agent, DM4, to kill the targeted cancer cells.

Authors Explore Overdiagnosis in Cancer Screening

Authors Explore Overdiagnosis in Cancer Screening

Standardized definition, guidance on estimation may facilitate understanding of overdiagnosis.

#DontFryDay: 12 Million Twitter Impressions Spread Message of Sun Safety

#DontFryDay: 12 Million Twitter Impressions Spread Message of Sun Safety

By

Social media is an ideal platform to reach teenagers and young adults to encourage sun safety.

Ribociclib Prolongs Progression-Free Survival in Premenopausal Breast Cancer

Ribociclib Prolongs Progression-Free Survival in Premenopausal Breast Cancer

By

Investigators report results from the MONALEESA-7 trial, which assessed ribociclib plus endocrine therapy in premenopausal women with advanced breast cancer.

More NPs Ordering Multitarget Stool DNA Test for Colorectal Cancer Screening

More NPs Ordering Multitarget Stool DNA Test for Colorectal Cancer Screening

By

The percentage of NPs who order the mt-sDNA test for colorectal cancer screening has increased significantly since the test became available in 2014.

Study Compares Treatment Options for T1a Renal Cancer

Study Compares Treatment Options for T1a Renal Cancer

Percutaneous ablation compared with partial, radical nephrectomy for 4,310 patients aged 66 years

Higher Vitamin D Levels Tied to Lower Risk of Colorectal Cancer

Higher Vitamin D Levels Tied to Lower Risk of Colorectal Cancer

In women, risk declines as levels increase up to 100 nmol/L, but association in men not significant

Older Adults Increasingly Have HPV&#43; Oropharyngeal Cancers

Older Adults Increasingly Have HPV+ Oropharyngeal Cancers

Regardless of age, favorable survival conferred by an HPV-positive tumor status

Cancer Development Linked to Increased Diabetes Risk

Cancer Development Linked to Increased Diabetes Risk

Increased risk of subsequent diabetes independent of traditional diabetes risk factors

Increase in Global Cancer Incidence, Drop in Death Rates

Increase in Global Cancer Incidence, Drop in Death Rates

From 2006 and 2016, smallest increase seen in high Sociodemographic Index countries.

Prophylactic, Extended Carboplatin Infusion Not Linked to Lower HSR in Ovarian Cancer Patients

Prophylactic, Extended Carboplatin Infusion Not Linked to Lower HSR in Ovarian Cancer Patients

By

A prophylactic, graded, extended infusion of carboplatin, compared with a shorter, standard infusion, is not associated with a reduced rate of HSRs in women with recurrent ovarian cancer.

Many Breast Cancer Survivors Do Not Undergo Annual Surveillance

Many Breast Cancer Survivors Do Not Undergo Annual Surveillance

In year 1, 13% did not undergo MRI or mammography; up to 19% by year 5.

ACS Updates Colorectal Cancer Screening to Start at Age 45

ACS Updates Colorectal Cancer Screening to Start at Age 45

Average-risk adults aged 45 should undergo high-sensitivity stool-based test, structural exam

Severe Folate Deficiency Associated With Olaparib for Relapsed Ovarian Cancer

Severe Folate Deficiency Associated With Olaparib for Relapsed Ovarian Cancer

In a case study, olaparib was found to induce folate deficiency in most patients with relapsed ovarian cancer. Researchers discuss the significance of this adverse effect and how it was managed.

Male Thyroid Cancer Survivors Face Higher CVD Risk

Male Thyroid Cancer Survivors Face Higher CVD Risk

Age at diagnosis, sex, BMI, and thyroid-stimulating hormone suppression therapy affect CVD risk

Prediction tool helps tailor lung cancer screening to patient benefit and preferences

Prediction tool may help physicians better personalize screening discussions with patients.

ACC Outlines Best Practices for Ionizing Radiation Use in Cardiovascular Imaging

ACC Outlines Best Practices for Ionizing Radiation Use in Cardiovascular Imaging

The American College of Cardiology, along with several other cardiology societies, have updated guidelines on best practices for improving safety when using ionizing radiation during cardiovascular imaging.

PSA Level 3 Months After Radiation Treatment May Predict Outcome

PSA Level 3 Months After Radiation Treatment May Predict Outcome

Findings for men with intermediate- and high-risk prostate cancer

Lung Cancer Incidence Higher for Young Women Than Young Men

Lung Cancer Incidence Higher for Young Women Than Young Men

Crossover in sex-specific rates among US non-Hispanic whites born since 1965

Hand Grip Strength Associated With All-Cause Mortality, Other Adverse Outcomes

Hand Grip Strength Associated With All-Cause Mortality, Other Adverse Outcomes

By

Grip strength is strongly and inversely associated with all-cause mortality and incidence of and mortality from cardiovascular disease, respiratory disease, COPD, all cancer, and subtypes of cancer, with associations being modestly stronger in the younger age groups.

Higher CRC Risk With Advanced Adenoma Found on Colonoscopy

Higher CRC Risk With Advanced Adenoma Found on Colonoscopy

Risk not increased for non-advanced adenoma found on colonoscopy following flex sigmoidoscopy

AAPA Responds to <i>JAMA Dermatology</i> Study

AAPA Responds to JAMA Dermatology Study

By

AAPA and SDPA respond to a recent article published in JAMA Dermatology.

Many Oncologists Discuss, Recommend Medical Marijuana

Many Oncologists Discuss, Recommend Medical Marijuana

But majority of oncologists don't feel knowledgeable enough to make these recommendations

Ovarian Cancer Patients May Benefit From Trabectedin With PLD

Ovarian Cancer Patients May Benefit From Trabectedin With PLD

By

For patients with platinum-sensitive recurrent ovarian cancer, trabectedin plus PLD may be beneficial.

Highly Selective, First-in-Class CDK4 Inhibitor Promising in Ovarian Cancer

Highly Selective, First-in-Class CDK4 Inhibitor Promising in Ovarian Cancer

Mice treated with 2-94 had few or no signs of lymphopenia or neutropenia, common adverse events associated with palbociclib.

Personalized Cancer Vaccine Looks Promising in Early Study

Personalized Cancer Vaccine Looks Promising in Early Study

By

The researchers enrolled 25 platinum-pretreated, immunotherapy-naïve patients with recurrent advanced epithelial ovarian cancer (EOC) for the trial.

Sign Up for Free e-newsletters