Opioids

CDC: EMS Administration of Naloxone Up From 2012 to 2016

CDC: EMS Administration of Naloxone Up From 2012 to 2016

Monitoring non-fatal overdose events from EMS data may aid in developing emergency response.

Outpatient Opioid Prescriptions for Children Often Filled

Outpatient Opioid Prescriptions for Children Often Filled

Cumulative incidence of opioid-related adverse events was 38.3 per 100,000 prescriptions.

Wide Variations in Opioid Prescribing Practices for Surgical Procedures

Wide Variations in Opioid Prescribing Practices for Surgical Procedures

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Variation exists in opioid prescribing practices among clinicians in single-hospital systems, which prompts concern about the potential for opioid overprescribing.

Preoperative Opioids Used by Nearly One-Quarter of Surgical Patients

Preoperative Opioids Used by Nearly One-Quarter of Surgical Patients

Odds of pre-op opioid use up with age 31 to 40 years, tobacco use, illicit drug use, depression.

Emergency Physicians Offer Recommendations for Identifying and Managing Opioid Use Disorder

Emergency Physicians Offer Recommendations for Identifying and Managing Opioid Use Disorder

American emergency medicine physicians have been taking measures to address the ongoing opioid crisis, which affects emergency departments throughout the country.

Any Opioid Use Tied to Involvement in Criminal Justice System

Any Opioid Use Tied to Involvement in Criminal Justice System

History of involvement with criminal justice system increased with intensity of drug use.

Pain Societies Issue Guidelines on Use of Ketamine for the Management of Acute Pain

Pain Societies Issue Guidelines on Use of Ketamine for the Management of Acute Pain

Consensus guidelines regarding the use of ketamine for the management of acute pain have been approved.

US Surgeon General Urges More Americans to Carry Naloxone

US Surgeon General Urges More Americans to Carry Naloxone

Surgeon General Jerome M. Adams, M.D., M.P.H., has urged more Americans to carry naloxone, an FDA-approved medication that can be delivered via nasal mist or injection and can temporarily suspend the effects of opioid overdose.

FDA Takes Steps to Reconcile Needs of Patients With Chronic Pain, Efforts to Curb Opioid Epidemic

FDA Takes Steps to Reconcile Needs of Patients With Chronic Pain, Efforts to Curb Opioid Epidemic

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A panel discussion event held at the US Food and Drug Administration gathered patients with chronic pain and FDA officials, to reconcile concerns around prescriptions of opioid medications with the needs of these patient populations.

Reproductive Dysfunction Risk in Women Taking Long-Term Opioids for Musculoskeletal Pain

Reproductive Dysfunction Risk in Women Taking Long-Term Opioids for Musculoskeletal Pain

Women prescribed long- vs short-term opioids for chronic musculoskeletal pain may be at increased risk for menopause and abnormal menstruation.

Chronic Pain Leads to Higher Opioid Doses and Lower QoL in Sickle Cell Patients

Chronic Pain Leads to Higher Opioid Doses and Lower QoL in Sickle Cell Patients

In adults with sickle cell disease, higher daily opioid use may be associated with poorer health-related quality of life.

Lofexidine a Non-Narcotic Option for Opioid Withdrawal Symptoms

Lofexidine a Non-Narcotic Option for Opioid Withdrawal Symptoms

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Lofexidine may help patients with opioid withdrawal symptoms or difficulty with opioid discontinuation.

Buprenorphine Diversion Driven by Withdrawal Prevention, Abstinence Maintenance

Buprenorphine Diversion Driven by Withdrawal Prevention, Abstinence Maintenance

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Researchers deployed a survey to individuals who had received treatment for opioid use disorder to assess their use of buprenorphine.

Oxycodone Substitute Shows Lower Abuse Potential

Oxycodone Substitute Shows Lower Abuse Potential

Investigators assessed the potential for abuse associated with NKTR-181, a new mu-opioid receptor agonist analgesic.

Transition to Naltrexone in Opioid Use Disorder Benefits from Psychosocial Assessment

Transition to Naltrexone in Opioid Use Disorder Benefits from Psychosocial Assessment

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A combination of naltrexone induction and psychoeducational counseling was found to facilitate transition from active opioid use and buprenorphine maintenance in individuals with opioid use disorder.

Recommendations for Perioperative Pain Management in Patients With Opioid Tolerance

Recommendations for Perioperative Pain Management in Patients With Opioid Tolerance

With the increasing number of patients presenting to surgery with opioid tolerance, clinicians should be familiar with their specific analgesic needs.

Meds for Opioid Use Disorder May Reduce Mortality in OD Survivors

Meds for Opioid Use Disorder May Reduce Mortality in OD Survivors

Minority of opioid overdose survivors receive MOUD; buprenorphine, MMT linked to reduced mortality

Rapid Decreasing Heroin Use During Opioid Substitution Treatment Associated With Treatment Success

Rapid Decreasing Heroin Use During Opioid Substitution Treatment Associated With Treatment Success

In patients receiving opioid substitution treatment for opioid use disorder (mainly involving heroin), those exhibiting a rapid decline in heroin use were found to be more likely to have successful treatment outcomes.

Wearable Device Cleared for Use During Opioid Detoxification

Wearable Device Cleared for Use During Opioid Detoxification

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Electrical pulses are sent through small needles that are inserted in the ear to combat the early stages of detoxification, leading to stabilization.

CDC: Invasive MRSA More Likely Among Injection Drug Users

CDC: Invasive MRSA More Likely Among Injection Drug Users

From 2011 to 2016, increase in invasive MRSA cases from 4.1 to 9.2 percent among injection drug users.

FDA Cracks Down on Illegal Online Sales of Opioids

FDA Cracks Down on Illegal Online Sales of Opioids

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The U.S. Food and Drug Administration has issued warnings to 9 online companies selling illegal opioid medications on 53 websites, in direct violation of the Federal Food, Drug, and Cosmetic Act.

Studies ID Impact of US Opioid-Related Mortality, Prescription Patterns

Studies ID Impact of US Opioid-Related Mortality, Prescription Patterns

Burden of deaths up; most patients receiving opioid analgesics use immediate-release formulations

FDA Approves Non-Opioid Treatment for Opioid Withdrawal

FDA Approves Non-Opioid Treatment for Opioid Withdrawal

Lucemyra is an oral selective alpha 2-adrenergic receptor agonist

Pharmaceutical Marketing Associated With Increased Opioid Prescription Rates

Pharmaceutical Marketing Associated With Increased Opioid Prescription Rates

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Payments correlated with prescribing opioids in 2014 may have influenced the increased prescription rates of 2015.

Opioid Education Program Boosts PA Students' Confidence in Providing Patient Care

Opioid Education Program Boosts PA Students' Confidence in Providing Patient Care

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PA students perceived improved confidence in their ability to provide patient education and counseling.

Naloxone Training Beneficial for PA Students

Naloxone Training Beneficial for PA Students

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Opioid-specific health seminars may help PA students learn lifesaving treatments to perform in the future.

Many Patients Have Unused Opioids After Spine, Joint Surgery

Many Patients Have Unused Opioids After Spine, Joint Surgery

Many patients reported unsafe storage and failure to dispose of opioids at one- and 6-month follow-up

Unit-Dose Packaging Cuts Accidental Peds Opioid Exposures

Unit-Dose Packaging Cuts Accidental Peds Opioid Exposures

Relative decrease in buprenorphine-naloxone exposure after transition to unit-dose packaging

Synthetic Opioid Involvement in Opioid-Related Deaths Increases

Synthetic Opioid Involvement in Opioid-Related Deaths Increases

From 2010 to 2016, synthetic opioid involvement up from 14.3 to 45.9% of opioid-related deaths

People With Opioid Use Disorder Have High Suicide Rate

People With Opioid Use Disorder Have High Suicide Rate

Based on data from multiple sources, many opioid-overdose deaths seem to be suicides

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