Intradetrusor injection of onabotulinumtoxin A impairs afferent and efferent nerves, but an injection-free drug delivery approach only impairs the bladder afferent nerves.
The FDA has approved Botox for adults with overactive bladder who can't use or don't respond to anticholinergics.
Myrbetriq is indicated for adults with overactive to minimize symptoms of frequent urination and urinary incontinence.
Toviaz works by relaxing the smooth muscle tissue of the bladder.
Add incontinence relief to the list of benefits obese patients gain from losing weight.