Pain

Preoperative Opioids Used by Nearly One-Quarter of Surgical Patients

Preoperative Opioids Used by Nearly One-Quarter of Surgical Patients

Odds of pre-op opioid use up with age 31 to 40 years, tobacco use, illicit drug use, depression.

Two-Thirds of Parents Report Their Child Has Had Headache

Two-Thirds of Parents Report Their Child Has Had Headache

Only 44 of parents would definitely go to ER if their child had headache that didn't improve with medication.

Radiofrequency Denervation Efficacious in Treating Thoracic Zygapophyseal Joint Pain

Radiofrequency Denervation Efficacious in Treating Thoracic Zygapophyseal Joint Pain

Radiofrequency denervation, typically used to treat lumbar and cervical zygapophyseal joint pain, has shown efficacy in treating thoracic zygapophyseal joint pain.

Emergency Physicians Offer Recommendations for Identifying and Managing Opioid Use Disorder

Emergency Physicians Offer Recommendations for Identifying and Managing Opioid Use Disorder

American emergency medicine physicians have been taking measures to address the ongoing opioid crisis, which affects emergency departments throughout the country.

Overuse of Neuroimaging in the Emergency Department Reported for Pediatric Headache

Overuse of Neuroimaging in the Emergency Department Reported for Pediatric Headache

Investigators examined rates, predictors, and outcomes of neuroimaging in pediatric and adolescent patients who presented to the ED with a headache.

US Surgeon General Urges More Americans to Carry Naloxone

US Surgeon General Urges More Americans to Carry Naloxone

Surgeon General Jerome M. Adams, M.D., M.P.H., has urged more Americans to carry naloxone, an FDA-approved medication that can be delivered via nasal mist or injection and can temporarily suspend the effects of opioid overdose.

FDA Takes Steps to Reconcile Needs of Patients With Chronic Pain, Efforts to Curb Opioid Epidemic

FDA Takes Steps to Reconcile Needs of Patients With Chronic Pain, Efforts to Curb Opioid Epidemic

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A panel discussion event held at the US Food and Drug Administration gathered patients with chronic pain and FDA officials, to reconcile concerns around prescriptions of opioid medications with the needs of these patient populations.

For Postpartum Hemorrhage, Carbetocin Similar to Oxytocin

For Postpartum Hemorrhage, Carbetocin Similar to Oxytocin

Heat-stable carbetocin non-inferior for preventing blood loss of 500 ml, use of other uterotonic agents

WHO Calls for Renewed Effort to Combat Chronic Disease

WHO Calls for Renewed Effort to Combat Chronic Disease

Commission makes 6 recommendations to meet 2030 goals for non-communicable diseases

Stat Consult: Chronic Low Back Pain

Stat Consult: Chronic Low Back Pain

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Chronic low back pain (LBP) defined as persistent or fluctuating musculoskeletal pain of lower back and lumbar spine lasting >3 months.

Chronic Pain Leads to Higher Opioid Doses and Lower QoL in Sickle Cell Patients

Chronic Pain Leads to Higher Opioid Doses and Lower QoL in Sickle Cell Patients

In adults with sickle cell disease, higher daily opioid use may be associated with poorer health-related quality of life.

FDA Upscheduling of Hydrocodone Places Burden on APRNs

FDA Upscheduling of Hydrocodone Places Burden on APRNs

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A study assessing the impact of upscheduling of hydrocodone combined medications on APRN practices in Oklahoma revealed significant barriers to effective pain management.

Buprenorphine Diversion Driven by Withdrawal Prevention, Abstinence Maintenance

Buprenorphine Diversion Driven by Withdrawal Prevention, Abstinence Maintenance

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Researchers deployed a survey to individuals who had received treatment for opioid use disorder to assess their use of buprenorphine.

NKTR-181 for Chronic Lower Back Pain:  SUMMIT-07 Results

NKTR-181 for Chronic Lower Back Pain: SUMMIT-07 Results

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The phase 3 SUMMIT-07 trial assessed the safety, efficacy, and tolerability of a new mu-opioid receptor agonist analgesic in adults with moderate to severe chronic lower back pain.

Oxycodone Substitute Shows Lower Abuse Potential

Oxycodone Substitute Shows Lower Abuse Potential

Investigators assessed the potential for abuse associated with NKTR-181, a new mu-opioid receptor agonist analgesic.

Transition to Naltrexone in Opioid Use Disorder Benefits from Psychosocial Assessment

Transition to Naltrexone in Opioid Use Disorder Benefits from Psychosocial Assessment

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A combination of naltrexone induction and psychoeducational counseling was found to facilitate transition from active opioid use and buprenorphine maintenance in individuals with opioid use disorder.

Budesonide ER for Ulcerative Colitis Safe Regardless of Gender, Age

Budesonide ER for Ulcerative Colitis Safe Regardless of Gender, Age

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The budesonide extended-release formulation was found to be safe and well tolerated for the remission of ulcerative colitis, regardless of age or gender.

Poison Control Center Data Detail Pediatric Exposure to Buprenorphine

Poison Control Center Data Detail Pediatric Exposure to Buprenorphine

Pediatric exposure to buprenorphine can result in serious adverse outcomes, especially among children aged younger than 6 years.

Post-Op Pain Treatment Gets Breakthrough Therapy Designation

Post-Op Pain Treatment Gets Breakthrough Therapy Designation

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The Company indicated that they will work towards an New Drug Application submission for the treatment in the second half of 2018.

Various Factors Affect Progress in Back-Related Leg Pain, Sciatica

Various Factors Affect Progress in Back-Related Leg Pain, Sciatica

Belief in a long recovery, many symptoms attributed to pain negatively tied to improvement

Meds for Opioid Use Disorder May Reduce Mortality in OD Survivors

Meds for Opioid Use Disorder May Reduce Mortality in OD Survivors

Minority of opioid overdose survivors receive MOUD; buprenorphine, MMT linked to reduced mortality

Rapid Decreasing Heroin Use During Opioid Substitution Treatment Associated With Treatment Success

Rapid Decreasing Heroin Use During Opioid Substitution Treatment Associated With Treatment Success

In patients receiving opioid substitution treatment for opioid use disorder (mainly involving heroin), those exhibiting a rapid decline in heroin use were found to be more likely to have successful treatment outcomes.

Wearable Device Cleared for Use During Opioid Detoxification

Wearable Device Cleared for Use During Opioid Detoxification

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Electrical pulses are sent through small needles that are inserted in the ear to combat the early stages of detoxification, leading to stabilization.

Restless Legs Syndrome, Fibromyalgia, and Depression Frequent in Migraine

Restless Legs Syndrome, Fibromyalgia, and Depression Frequent in Migraine

Patients with migraine may exhibit higher prevalence of restless leg syndrome, fibromyalgia, and depressive symptoms compared with individuals not experiencing migraines.

Corticosteroid Plus Lidocaine Injections Do Not Alleviate Pain in Central Lumbar Spinal Stenosis

Corticosteroid Plus Lidocaine Injections Do Not Alleviate Pain in Central Lumbar Spinal Stenosis

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Adding corticosteroids to epidural lidocaine injections does not improve patient-reported pain or function at 12 months.

FDA Cracks Down on Illegal Online Sales of Opioids

FDA Cracks Down on Illegal Online Sales of Opioids

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The U.S. Food and Drug Administration has issued warnings to 9 online companies selling illegal opioid medications on 53 websites, in direct violation of the Federal Food, Drug, and Cosmetic Act.

Cryoablation Efficacious for Cancer Pain, Review Finds

Cryoablation Efficacious for Cancer Pain, Review Finds

Cryoablation also cuts the need for opioids at 24 hours post-treatment and at three months

Studies ID Impact of US Opioid-Related Mortality, Prescription Patterns

Studies ID Impact of US Opioid-Related Mortality, Prescription Patterns

Burden of deaths up; most patients receiving opioid analgesics use immediate-release formulations

PTSD Symptoms and the Acute Pain Response in Low-Income Women

PTSD Symptoms and the Acute Pain Response in Low-Income Women

Posttraumatic stress disorder symptoms may be associated with higher levels of acute pain and pain interference in low-income inner city women.

FDA Approves Non-Opioid Treatment for Opioid Withdrawal

FDA Approves Non-Opioid Treatment for Opioid Withdrawal

Lucemyra is an oral selective alpha 2-adrenergic receptor agonist

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