Pharmaceuticals

American College of Physicians recommends prescribing generic medications

American College of Physicians recommends prescribing generic medications

Clinicians should prescribe generic medications over brand-name drugs when they can because the generics are less expensive and molecularly identical.

Clinician access on the decline for pharmaceutical reps

Clinician access on the decline for pharmaceutical reps

A new survey indicates that pharmaceutical representatives have restricted access to over half of clinicians.

Breakthrough therapy for HCV infection

Breakthrough therapy for HCV infection

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Sofosbuvir is indicated for use with other medications as part of an antiviral treatment regimen for chronic hepatitis C infection.

Improved 
control of 
seizures

Improved 
control of 
seizures

Fycompa is indicated to treat partial-onset seizures in patients aged 12 years and older.

GSK ends physician speaking fees

GSK ends physician speaking fees

Pharmaceutical giant first drug maker to adopt such a policy and may encourage others to follow suit.

FDA investigating death of two patients on Zyprexa

FDA investigating death of two patients on Zyprexa

The FDA is looking into the cause of death of two patients who died several days after receiving injections of Zyprexa Relprevv.

Myrbetriq safe, effective alternative for OAB

Myrbetriq safe, effective alternative for OAB

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High discontinuation rates with traditional second-line therapies suggest more overactive bladder treatment options are needed.

FDA approves abuse-deterrent OxyContin labeling

FDA approves abuse-deterrent OxyContin labeling

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As the patent on the original formulation expires, the FDA introduces new label and blocks NDAs for generic versions that lack abuse-deterrent properties.

Desperation leads patients online for Rx meds

Desperation leads patients online for Rx meds

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Clinicians must carefully question our patients about the source of their prescription drugs to make sure they are obtaining these products from legitimate sources.

FDA calls for new rules for compounding pharmacies

FDA calls for new rules for compounding pharmacies

Greater cooperation needed between federal and state health inspectors to oversee compounding pharmacies, which fall into a regulatory gray zone between various state and federal laws.

Qualitest recalls hydrocodone bitartrate and acetaminophen tablets

Qualitest recalls hydrocodone bitartrate and acetaminophen tablets

Drug manufacturer Qualitest has issued a nationwide voluntary recall of one lot of hydrocodone bitartrate and acetaminophen 10mg/500mg tablets due to potentially over-sized tablets.

Bosutinib approved for chronic myelogenous leukemia

Bosutinib approved for chronic myelogenous leukemia

The FDA has approved bosutinib (Bosulif, Pfizer) for patients with chronic, accelerated or blast phase Philadelphia chromosome positive CML, who are resistant to or who cannot tolerate other therapies.

New drug approved for chemo-related severe neutropenia

New drug approved for chemo-related severe neutropenia

The FDA has approved tbo-filgrastim to treat neutropenia in patients with nonmyeloid malignancies, who receive myelosuppressive chemotherapy.

Pediatric everolimus dose approved to treat rare brain tumor

Pediatric everolimus dose approved to treat rare brain tumor

The first pediatric form of the cancer drug everolimus has been sanctioned to treat rare brain tumors in children aged 1 year and older.

FDA approves Linzess for IBS, chronic constipation

FDA approves Linzess for IBS, chronic constipation

Linzess sanctioned for constipation that does not respond to conventional treatment.

Online Adderall may contain wrong active ingredients

Online Adderall may contain wrong active ingredients

FDA warns that counterfeit drug may be ineffective and potentially harmful.

FDA places restrictions on oral MS drug

FDA places restrictions on oral MS drug

The FDA has added new contraindications to fingolimod's label, and more detailed recommendations for monitoring patients after dosing.

Hydromorphone HCl injection 1mg/mL recalled due to overdose risk

Prefilled glass cartridges of hydromorphone HCI injection 1 mg/mL manufactured by Hospira may contain more than the labeled 1 mL fill volume.

Epinephrine injection recalled due to visible particulate matter

American Regent has issued a nationwide voluntary recall of epinephrine injection, 1:1000, 1mL ampules after concerns that visible particulates in some ampules could cause adverse events if administered intravenously.

Natazia approved for heavy menstrual bleeding

The FDA has approved the oral contraceptive, Natazia, to treat women with heavy menstrual bleeding that is not caused by a diagnosed condition of the uterus.

FDA approves respiratory distress drug for infants

FDA approves respiratory distress drug for infants

Surfaxin (lucinactant) is indicated for the prevention of respiratory distress syndrome, a breathing disorder that affects premature infants.

FDA adds drug interaction warnings to Lipitor, Crestor and Zocor

Drug interactions between statins and certain protease inhibitors for HIV or hepatitis C can increase the risk for myopathy, including rhabdomyolysis.

Sleeping pill deaths may exceed 500,000 annually

Sleeping pill deaths may exceed 500,000 annually

Sleeping pill use was associated with a three- to five-fold higher mortality risk compared to nonuse, even among patients taking relatively few pills a year.

Generic oral contraceptives recalled due to packaging error

Generic oral contraceptives recalled due to packaging error

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Glenmark Generics Inc. has issued a voluntary nationwide recall of seven lots of the oral contraceptives norgestimate and ethinyl estradiol, after consumers reported that the tablets in some packages were in reverse order.

Phenylephrine HCl injection recalled

American Regent has issued a nationwide voluntary recall of Phenylephrine HCl Injection, USP, 1% (10mg/mL), 5mL vials.

Infants' Tylenol oral suspension recalled

McNeil Consumer Healthcare is voluntarily recalling seven lots of Infants' Tylenol Oral Suspension, 1oz Grape, distributed nationwide in the U.S.

FDA warns of counterfeit Avastin

The FDA is warning health care professionals about a counterfeit version of Avastin 400mg/16mL, which may have been purchased and used by some medical practices in the United States.

Hepatitis C therapy interferes with HIV treatment

Taking boceprevir with ritonavir-boosted HIV protease inhibitors together reduces the effectiveness of both therapies, the FDA announced.

Janumet XR approved for type 2 diabetes

Merck announced that the FDA has approved Janumet XR (sitagliptin/metformin HCl extended-release tablets) for the treatment of type 2 diabetes.

Gleevec indications expanded to include rare cancer

Gleevec indications expanded to include rare cancer

The FDA expanded indications for imatinib mesylate tablets (Gleevec, Novartis) to include patients who have had CD117-positive gastrointestinal stromal tumors surgically removed.

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