Generic Name and Formulations:
Phentolamine mesylate 5mg/vial; for IM or IV inj after reconstitution; contains mannitol.
Various generic manufacturers
Indications for Phentolamine:
Hypertensive episodes in patients with pheochromocytoma.
Pre-op: 5mg IV or IM 1–2 hrs before surgery; may repeat. During surgery: 5mg IV as needed. See literature.
Pre-op: 1mg IV or IM 1–2 hrs before surgery; may repeat. During surgery: 1mg IV as needed. See literature.
MI or history of MI. Coronary insufficiency. Angina. Coronary artery disease.
Arrhythmias. Pregnancy (Cat.C). Nursing mothers: not recommended.
Avoid concomitant cardiac glycosides.
Alpha adrenergic blocker.
Cerebrovascular spasms or occlusion, MI, tachycardia, arrhythmias, hypotension, weakness, dizziness, flushing, nasal congestion, GI disturbances.
Formerly known under the brand name Regitine.