Drug Name:
Phentolamine Rx
Generic Name and Formulations:
Phentolamine mesylate 5mg/vial; for IM or IV inj after reconstitution; contains mannitol.
Company:
Various generic manufacturers
Therapeutic Use:
Indications for Phentolamine:
Hypertensive episodes in patients with pheochromocytoma.
Adult:
Pre-op: 5mg IV or IM 1–2 hrs before surgery; may repeat. During surgery: 5mg IV as needed. See literature.
Children:
Pre-op: 1mg IV or IM 1–2 hrs before surgery; may repeat. During surgery: 1mg IV as needed. See literature.
Contraindications:
MI or history of MI. Coronary insufficiency. Angina. Coronary artery disease.
Warnings/Precautions:
Arrhythmias. Pregnancy (Cat.C). Nursing mothers: not recommended.
Pharmacological Class:
Alpha adrenergic blocker.
Interactions:
Avoid concomitant cardiac glycosides.
Adverse Reactions:
Cerebrovascular spasms or occlusion, MI, tachycardia, arrhythmias, hypotension, weakness, dizziness, flushing, nasal congestion, GI disturbances.
Note:
Formerly known under the brand name Regitine.
How Supplied:
Vial—1
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