Polymyxin B/Neomycin/Bacitracin/Hydrocortisone Oph Oint Rx
Generic Name and Formulations:
Polymyxin B sulfate 10000 Units, neomycin 0.35% (as sulfate), bacitracin zinc 400 Units, hydrocortisone 1%; per g.
Various generic manufacturers
Indications for Polymyxin B/Neomycin/Bacitracin/Hydrocortisone Oph Oint:
Ocular inflammation associated with infection.
1–2 drops or small amount of oint every 3–4 hours (may use susp more often); max 20mL or 8g per therapeutic course.
Ocular fungal, viral or mycobacterial infections.
Corneal or scleral thinning. Glaucoma. Monitor IOP, for secondary infections, and avoid abrupt cessation in prolonged use. Pregnancy (Cat.C). Nursing mothers: not recommended.
Antibiotics + steroid.
Local irritation, sensitization, masks infection, delays healing; in prolonged use: increased IOP, cataracts, corneal perforation, optic nerve damage.
Formerly known under the brand name Cortisporin.