Sepsis

New York State Mandate for Pediatric Sepsis Bundled Care Linked to Lower Mortality

New York State Mandate for Pediatric Sepsis Bundled Care Linked to Lower Mortality

Completion of a care bundle for pediatric patients within 1 hour of sepsis recognition, which includes blood cultures, broad-spectrum antibiotics, and a 20-mL/kg intravenous fluid bolus, was associated with lower in-hospital mortality among children with sepsis and septic shock

Completing Sepsis Bundle Within an Hour Cuts Pediatric Mortality

Completing Sepsis Bundle Within an Hour Cuts Pediatric Mortality

However, completing individual bundle elements in that timeframe does not reduce pediatric mortality.

Complex government-mandated sepsis performance measures not shown to improve survival

No moderate- or high-level evidence was found that SEP-1 or its hemodynamic interventions increase survival in septic adults.

Glucocorticoid treatment ineffective for reducing sepsis-related mortality

Glucocorticoid treatment ineffective for reducing sepsis-related mortality

By

Hydrocortisone treatment does not effectively reduce mortality in sepsis.

Norepinephrine shortage led to higher mortality in septic shock patients

Norepinephrine shortage led to higher mortality in septic shock patients

By

Patients with septic shock taking phenylephrine during the 2011 norepinephrine shortage experienced higher in-hospital mortality rates.

Short-term oral corticosteroid use associated with increased risk for sepsis, venous thromboembolism

Short-term oral corticosteroid use associated with increased risk for sepsis, venous thromboembolism

By

Approximately 1 in 5 American adults use corticosteroids in the short term, which is associated with an increased risk for sepsis, venous thromboembolism, and fracture.

Septic shock: early, goal-directed therapy versus usual care

Septic shock: early, goal-directed therapy versus usual care

By

Early, goal-directed therapy did not result in better outcomes for mortality for patients with septic shock.

Sepsis risk calculator helps decrease antibiotic use in infants

Sepsis risk calculator helps decrease antibiotic use in infants

By

Data presented at NAPNAP show that an early-onset sepsis calculator can decrease the number of infants who received a sepsis work-up and prophylactic antibiotics.

Definitions for sepsis, septic shock issued

Definitions for sepsis, septic shock issued

By

Sepsis should be defined as life-threatening organ dysfunction as a response to infection.

Sign Up for Free e-newsletters