Generic Name and Formulations:
Minocycline (as HCl) 45mg, 90mg, 135mg; ext-rel tabs.
Medicis Pharmaceuticals Corp
Indications for SOLODYN:
Inflammatory lesions of non-nodular moderate to severe acne.
Swallow whole. Give once daily for up to 12 weeks. Dose based on weight: approximately 1mg/kg. 45–59kg: 45mg. 60–90kg: 90mg. 91–136kg: 135mg. Renal impairment: reduce dose or extend dosing intervals.
Not interchangeable with other minocycline products. Renal or hepatic impairment. Monitor blood, renal, or hepatic function. Pregnancy (Cat.D), nursing mothers: not recommended.
Antacids, iron, zinc, calcium, magnesium, urinary alkalinizers reduce absorption. Avoid penicillins, methoxyflurane, isotretinoin. Monitor PT with oral anticoagulants. May antagonize oral contraceptives.
Headache, fatigue, dizziness, GI upset, rash, increased BUN, hepatotoxicity, tinnitus, tooth discoloration, pseudotumor cerebri, photosensitivity, hyperpigmentation, autoimmune syndromes.
Tabs—30, 90, 100