Statins

Ending statin therapy after initial stroke increases risk of recurrence

Ending statin therapy after initial stroke increases risk of recurrence

Stopping statin therapy 3 to 6 months after an initial ischemic stroke may increase risk of a recurrent stroke.

Statins vs usual care for primary cardiovascular prevention in older adults

Statins vs usual care for primary cardiovascular prevention in older adults

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The ALLHAT-LLT trial showed that statin therapy for primary cardiovascular prevention may not benefit adults older than 65 years of age.

Statin eligibility differs between ACC/AHA vs USPSTF guidelines

Statin eligibility differs between ACC/AHA vs USPSTF guidelines

Nine million fewer adults would be taking statins if clinicians followed the USPSTF guidelines.

Statins may reduce pulmonary artery pressure in COPD patients

Statins may reduce pulmonary artery pressure in COPD patients

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A daily dose of atorvastatin could reduce pulmonary artery pressure among patients with COPD.

Statin prescription rates lower among younger adults with severe dyslipidemia

Statin prescription rates lower among younger adults with severe dyslipidemia

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Prescription rates for statins were dependent on age among patients with severe dyslipidemia.

Women using statins may have a lower risk of uterine fibroids

Women using statins may have a lower risk of uterine fibroids

Researchers examined the association between statin use and the risk of uterine fibroids and fibroid-related symptoms.

Statins may reduce risk of Alzheimer's disease

Statins may reduce risk of Alzheimer's disease

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Depending on race, sex, and ethnicity, the right statin type may lower the risk of Alzheimer disease.

Statin and PCSK9 inhibitor combination more effective at lowering cholesterol

Statin and PCSK9 inhibitor combination more effective at lowering cholesterol

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PCSK9 inhibition produces incremental benefits on coronary disease progression in patients treated with statins.

USPSTF releases final statin recommendations for CVD prevention

USPSTF releases final statin recommendations for CVD prevention

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The task force finalizes recommendations for statin therapy among adults between 40 and 75 years of age.

Statin-based therapy less effective in advanced chronic kidney disease

Statin-based therapy less effective in advanced chronic kidney disease

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Statin-based therapy had a smaller effect in reducing major vascular events in patients with advanced chronic kidney disease.

Alternative non-statin therapies effectively lower LDL cholesterol

Alternative non-statin therapies effectively lower LDL cholesterol

Researchers found that dietary changes, other medications, and surgery can also lower cardiovascular risk.

Statins may benefit intermediate-risk patients without CVD

Statins may benefit intermediate-risk patients without CVD

Results from a study presented at ACC in Chicago suggest that statins can be more widely used in patients considered to be intermediate risk for cardiovascular disease.

The anti-inflammatory effects of statins

The anti-inflammatory effects of statins

Is the real benefit of statins their anti-inflammatory benefits?

Statins slow progression of liver disease in patients with HIV, Hep C

Statins slow progression of liver disease in patients with HIV, Hep C

Statin use in co-infected patients showed a slowed progression of liver disease, according to a study conducted at the Johns Hopkins Moore Clinic for HIV Care.

Statins cost-effective in adults aged 40-75 years

Statins cost-effective in adults aged 40-75 years

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For older adults at risk for heart attack or stroke, statin use is cost effective in 48% to 67% of patients.

Statins linked to higher aggression in women, lower aggression in men

Statins linked to higher aggression in women, lower aggression in men

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While statins may decrease aggression in men, they appear to increase it in postmenopausal women.

Subclinical hypothyroidism plus statins increase diabetes risk

Subclinical hypothyroidism plus statins increase diabetes risk

Patients with subclinical hypothyroidism who take statins have an increased risk of developing diabetes.

Statin discontinuation may increase quality of life in patients with life-limiting illness

Statin discontinuation may increase quality of life in patients with life-limiting illness

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Patients with life-limiting illnesses often take statins, and discontinuing these can increase quality of life.

Discussion urged with statins

Discussion urged with statins

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Clinicians should clearly explain the risks and benefits to patients beginning statin therapy.

Applying pediatric cholesterol guidelines would increase statin use

Applying pediatric cholesterol guidelines would increase statin use

Under the pediatric guidelines, 2.5% of the patients surveyed would qualify for statin treatment while only 0.4% would qualify under the adult guidelines.

Gender 
effects 
of statins

Gender 
effects 
of statins

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A patient's gender does not affect the efficacy of statin therapy for major vascular events.

Statin use poses low risk of hepatic injury in liver disease

Statin use poses low risk of hepatic injury in liver disease

There was no difference overall in the incidence with different statins, but high-dose atorvastatin was associated with increased hospitalization.

Statin use advised in chronic kidney disease


Statin use advised in chronic kidney disease


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A new study indicated that older patients with predialysis chronic kidney disease should take statins.

Telephone reminders up cardiovascular disease medication adherence

Telephone reminders up cardiovascular disease medication adherence

Small but statistically significant improvements in adherence were seen among intervention participants.

Statins cut microvascular risk in diabetes

Statins cut microvascular risk in diabetes

Compared with patients who had not taken statins, those who had were less likely to develop diabetic neuropathy by 34%, diabetic retinopathy by 40%, and gangrene by 12%.

Statin efficacy varies widely from patient to patient

Statin efficacy varies widely from patient to patient

More than 40% of those taking high-dose statins don't reach LDL-C target of <70 mg/dL

New guidelines expand statin eligibility by 13 million

New guidelines expand statin eligibility by 13 million

Increase largely driven by eligibility of adults aged 60 years and older without cardiovascular disease in the primary prevention setting.

No link between statins and cognition

No link between statins and cognition

A systematic review of available evidence uncovered no association between the use of statins and adverse cognitive outcomes.

Statin benefits outweigh risk of developing diabetes

Statin benefits outweigh risk of developing diabetes

Diabetes risk only increased in those with one or more major risk factors.

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