Statins

Statin and PCSK9 inhibitor combination more effective at lowering cholesterol

Statin and PCSK9 inhibitor combination more effective at lowering cholesterol

By

PCSK9 inhibition produces incremental benefits on coronary disease progression in patients treated with statins.

USPSTF releases final statin recommendations for CVD prevention

USPSTF releases final statin recommendations for CVD prevention

By

The task force finalizes recommendations for statin therapy among adults between 40 and 75 years of age.

Statin-based therapy less effective in advanced chronic kidney disease

Statin-based therapy less effective in advanced chronic kidney disease

By

Statin-based therapy had a smaller effect in reducing major vascular events in patients with advanced chronic kidney disease.

Alternative non-statin therapies effectively lower LDL cholesterol

Alternative non-statin therapies effectively lower LDL cholesterol

Researchers found that dietary changes, other medications, and surgery can also lower cardiovascular risk.

Statins may benefit intermediate-risk patients without CVD

Statins may benefit intermediate-risk patients without CVD

Results from a study presented at ACC in Chicago suggest that statins can be more widely used in patients considered to be intermediate risk for cardiovascular disease.

The anti-inflammatory effects of statins

The anti-inflammatory effects of statins

Is the real benefit of statins their anti-inflammatory benefits?

Statins slow progression of liver disease in patients with HIV, Hep C

Statins slow progression of liver disease in patients with HIV, Hep C

Statin use in co-infected patients showed a slowed progression of liver disease, according to a study conducted at the Johns Hopkins Moore Clinic for HIV Care.

Statins cost-effective in adults aged 40-75 years

Statins cost-effective in adults aged 40-75 years

By

For older adults at risk for heart attack or stroke, statin use is cost effective in 48% to 67% of patients.

Statins linked to higher aggression in women, lower aggression in men

Statins linked to higher aggression in women, lower aggression in men

By

While statins may decrease aggression in men, they appear to increase it in postmenopausal women.

Subclinical hypothyroidism plus statins increase diabetes risk

Subclinical hypothyroidism plus statins increase diabetes risk

Patients with subclinical hypothyroidism who take statins have an increased risk of developing diabetes.

Statin discontinuation may increase quality of life in patients with life-limiting illness

Statin discontinuation may increase quality of life in patients with life-limiting illness

By

Patients with life-limiting illnesses often take statins, and discontinuing these can increase quality of life.

Discussion urged with statins

Discussion urged with statins

By

Clinicians should clearly explain the risks and benefits to patients beginning statin therapy.

Applying pediatric cholesterol guidelines would increase statin use

Applying pediatric cholesterol guidelines would increase statin use

Under the pediatric guidelines, 2.5% of the patients surveyed would qualify for statin treatment while only 0.4% would qualify under the adult guidelines.

Gender 
effects 
of statins

Gender 
effects 
of statins

By

A patient's gender does not affect the efficacy of statin therapy for major vascular events.

Statin use poses low risk of hepatic injury in liver disease

Statin use poses low risk of hepatic injury in liver disease

There was no difference overall in the incidence with different statins, but high-dose atorvastatin was associated with increased hospitalization.

Statin use advised in chronic kidney disease


Statin use advised in chronic kidney disease


By

A new study indicated that older patients with predialysis chronic kidney disease should take statins.

Telephone reminders up cardiovascular disease medication adherence

Telephone reminders up cardiovascular disease medication adherence

Small but statistically significant improvements in adherence were seen among intervention participants.

Statins cut microvascular risk in diabetes

Statins cut microvascular risk in diabetes

Compared with patients who had not taken statins, those who had were less likely to develop diabetic neuropathy by 34%, diabetic retinopathy by 40%, and gangrene by 12%.

Statin efficacy varies widely from patient to patient

Statin efficacy varies widely from patient to patient

More than 40% of those taking high-dose statins don't reach LDL-C target of <70 mg/dL

New guidelines expand statin eligibility by 13 million

New guidelines expand statin eligibility by 13 million

Increase largely driven by eligibility of adults aged 60 years and older without cardiovascular disease in the primary prevention setting.

No link between statins and cognition

No link between statins and cognition

A systematic review of available evidence uncovered no association between the use of statins and adverse cognitive outcomes.

Statin benefits outweigh risk of developing diabetes

Statin benefits outweigh risk of developing diabetes

Diabetes risk only increased in those with one or more major risk factors.

Statin label to carry diabetes warning

By

The FDA warns of a small increased risk for elevated blood glucose levels and possible problems with transient memory and cognition with statin use.

Statin use pays off without causing cancer

Statin use pays off without causing cancer

By

A large, long-term project by the Heart Protection Study Collaborative Group showed that statin therapy increasingly reduced heart attack, stroke, and other vascular disease as treatment continued, and that these benefits persisted for several years after treatment had stopped.

Does gender affect statin efficacy?

Is there evidence showing that women taking statins saw little improvement in their lipid levels?

Statins lowered death risk associated with flu hospitalization

Statins lowered death risk associated with flu hospitalization

Statins given before or during hospitalization reduced mortality in adults with influenza.

Keep using statins despite diabetes risk

Keep using statins despite diabetes risk

Clinical practice in patients with moderate or high cardiovascular risk or existing cardiovascular disease should not change.

Sign Up for Free e-newsletters