Single high-dose liposomal amphotericin B (L-AmB) is non-inferior to daily dosed L-AmB at the standard dose in treatment of fungal clearance in HIV-associated cryptococcal meningitis.
A study was conducted to evaluate the oxazolidinone resistance mechanisms of enterococci bacteria.
First-line chemotherapy in combination with bevacizumab, compared with chemotherapy alone, may benefit patients with ovarian cancer and elevated neutrophil-to-lymphocyte ratios.
Study patients who received Avastin plus chemotherapy followed by Avastin alone, had a greater median PFS vs patients who received chemotherapy alone (18.2 months vs 12 months; hazard ratio [HR] 0.62, 95% CI, 0.52-0.75; P<.0001).
Valve has been approved after review of data from trial involving 190 patients with emphysema
Mirvetuximuab soravtansine uses a humanized FRα-binding antibody to target antibody-drug conjugates specifically to FRα-expressing cancer cells and a potent anti-tumor agent, DM4, to kill the targeted cancer cells.
DBS has been known to generate other movement-related disorders such as dyskinesias, blepharospasm, and hypokinesia.
The final analysis set comprised biologic-naïve individuals — individuals who had filled an initial prescription for etanercept, infliximab, adalimumab, or ustekinumab after 2 years without using any biologic agent during the study period.
In patients with and without dementia, amyloid-positive and negative results were significantly linked to diagnoses and treatment changes.
Researchers conducted a retrospective matched cohort study to compare the risk of death among BPH patients treated with 5ARIs, as monotherapy or in combination with alpha-blockers, and those treated with alpha-blockers alone.
In 2003, the Human Genome Project became the culmination of the history of genetics research, allowing us to understand the role of genetics in human health and disease. As part of The Clinical Advisor's 20th Anniversary, this article explores the influence of race and genetics in clinical practice.
Patients with mild, moderate renal impairment showed improvement in renal biomarkers over one year
Microneedling combined with bleomycin was associated with higher clearance rates and was less painful than the use of intralesional bleomycin injections.
In patients with mild asthma, use of the inhaled combined corticosteroid and beta agonist budesonide-formoterol as needed was superior to terbutaline as needed with respect to electronically recorded weeks of well-controlled asthma.
Oral medication, botulinum toxin type A injections, and endoscopic decompression surgery were all compared in the treatment of patients with frontal secondary headaches due to STN and SON configuration.
Payments correlated with prescribing opioids in 2014 may have influenced the increased prescription rates of 2015.
Researchers found a positive but weak correlation between psychological interventions and chronic pain treatment in older adults.
But majority of oncologists don't feel knowledgeable enough to make these recommendations
For patients with platinum-sensitive recurrent ovarian cancer, trabectedin plus PLD may be beneficial.
Mice treated with 2-94 had few or no signs of lymphopenia or neutropenia, common adverse events associated with palbociclib.
Clinics claim unapproved therapies can treat number of diseases and conditions, including ALS and cancer
Vigil immunotherapy is possible for women with recurrent ovarian cancer and PARP 7 may impact ovarian cancer survival, according to two studies presented in New Orleans.
Researchers assessed the use of dupilumab in adults with chronic rhinosinusitis and nasal polyps who did not respond to treatment with intranasal corticosteroids.
Among patients admitted to the hospital for a provisional diagnosis of cellulitis, early dermatologic consultation was associated with improved recognition of pseudo-cellulitis, decreased antibiotic use, and earlier discharge.
The addition of HIPEC resulted in longer recurrence-free and overall survival among patients with ovarian cancer.
Hydrocortisone treatment does not effectively reduce mortality in sepsis.
Bimodal auditory-somatosensory treatment is noninvasive and showed no side effects.
New FDA-approved prophylactic treatment decreases bleeding episodes hemophilia A patients with factor VIII inhibitors.