Generic Name and Formulations:
Dorzolamide HCl 2%; oph soln; contains benzalkonium chloride.
Merck & Co., Inc.
Indications for TRUSOPT:
Open-angle glaucoma. Ocular hypertension.
Adults and Children:
1 drop 3 times daily.
Hepatic impairment. Severe renal impairment (CrCl <30mL/min): not recommended. Discontinue if ocular effects (eg, conjunctivitis, lid reactions) occur. Soft contact lenses. Pregnancy (Cat.C). Nursing mothers: not recommended.
Carbonic anhydrase inhibitor (sulfonamide).
Concomitant oral carbonic anhydrase inhibitors: not recommended. May inhibit renal excretion of basic drugs and promote excretion of acidic drugs. May increase salicylate toxicity (acidosis).
Burning, stinging, bitter taste, punctate keratitis, ocular allergic reaction, blurred vision, tearing, dryness, photophobia; possible sulfa-like systemic effects.