Type 2 Diabetes

Commercial weight loss program may help prevent diabetes in obese patients

Commercial weight loss program may help prevent diabetes in obese patients

Primary care referral to Weight Watchers meetings is associated with weight loss, HbA1c reduction.

Statins associated with increased risk of diabetes in high-risk individuals

Statins associated with increased risk of diabetes in high-risk individuals

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Statins are associated with an increased risk for developing type 2 diabetes, especially for high-risk individuals.

Cognitive behavioral group therapy ineffective for weight maintenance in type 2 diabetes

Cognitive behavioral group therapy ineffective for weight maintenance in type 2 diabetes

CBGT did not prevent overweight and obese patients with type 2 diabetes from regaining weight lost during weight loss programs.

Antidepressant use linked to type 2 diabetes in young adults

Antidepressant use linked to type 2 diabetes in young adults

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Type 2 diabetes risk is increased in young adults through antidepressant use, specifically the duration of use and the cumulative dose.

Diabetes risk greater in children, young adults on second-generation antipsychotics

Diabetes risk greater in children, young adults on second-generation antipsychotics

Type 2 diabetes is greater with second-generation antipsychotics than with non-second-generation antipsychotic psychotropic medications for patients aged 6 to 25 years.

Evidence finds link between antidepressant drug use and type 2 diabetes

Evidence finds link between antidepressant drug use and type 2 diabetes

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After the inclusion of recent negative studies, a statistically significant association between AD use and diabetes was observed.

Shorter sleep duration linked to higher diabetes risk in children

Shorter sleep duration linked to higher diabetes risk in children

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Sleep duration for 1 hour longer was associated with lower BMI, fat mass, insulin resistance, and fasting glucose but had no effect on HbA1c or cardiovascular risk.

Lifestyle intervention provides minimal benefit in improving glycemic control in type 2 diabetes

Lifestyle intervention provides minimal benefit in improving glycemic control in type 2 diabetes

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Lifestyle interventions maintain glycemic control in patients with type 2 diabetes.

Earlier menopause may increase risk of type 2 diabetes

Earlier menopause may increase risk of type 2 diabetes

Women who experienced early menopause were 2.4 times more likely to develop diabetes.

Moderate weight gain in early to middle adulthood linked to increased risk of chronic diseases

Moderate weight gain in early to middle adulthood linked to increased risk of chronic diseases

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Adulthood weight gain is associated with an increased risk of major chronic diseases and mortality.

Type 2 diabetes patients benefit from depression screening

Type 2 diabetes patients benefit from depression screening

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The annual screening could decrease negative health outcomes and may be a cost-effective way to reduce complications.

Degludec vs glargine in type 2 diabetes for cardiovascular events

Degludec vs glargine in type 2 diabetes for cardiovascular events

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Degludec is noninferior to glargine regarding the incidence of major cardiovascular events among patients with type 2 diabetes.

Some antidiabetic agents may increase pneumonia risk in type 2 diabetes

Some antidiabetic agents may increase pneumonia risk in type 2 diabetes

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Compared with current use of metformin + sulfonylurea, the use of thiazolidinediones + metformin was associated with an increased risk of community-acquired pneumonia.

Insulin pump therapy improves quality of life in adolescents with type 2 diabetes

Insulin pump therapy improves quality of life in adolescents with type 2 diabetes

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Adolescents with type 2 diabetes decreased HbA1c levels after using insulin pump therapy for a 3-month period.

High BMI in late adolescence associated with increased risk of severe liver disease in men

High BMI in late adolescence associated with increased risk of severe liver disease in men

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A high BMI is associated with an increased risk for severe liver disease, and the risk is higher in those who also have type 2 diabetes mellitus.

Insulin initiation in primary care improves HbA1c levels

Insulin initiation in primary care improves HbA1c levels

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The Stepping Up model of care produced a clinically and significantly significant improvement in HbA1c among adults with type 2 diabetes managed in primary care.

Nearly half of all cardiometabolic deaths linked to poor diet

Nearly half of all cardiometabolic deaths linked to poor diet

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Suboptimal intake of 10 specific dietary factors is associated with a substantial proportion of deaths due to heart disease, stroke, or type 2 diabetes.

Metformin, vildagliptin have differing effects on heart rate, blood pressure in diabetes

Metformin, vildagliptin have differing effects on heart rate, blood pressure in diabetes

Vildagliptin lowers blood pressure and elevates heart rate, while metformin increases heart rate with no effect on blood pressure.

Lifestyle modifications vs pharmacologic treatment for patients with diabetes

Lifestyle modifications vs pharmacologic treatment for patients with diabetes

Applying necessary lifestyle changes as well as incorporating pharmaceutical drugs will improve diabetes in patients compared to drugs alone.

Case Study in Diabetes: Use of DPP-4 inhibitors with GLP-1 agonists

Case Study in Diabetes: Use of DPP-4 inhibitors with GLP-1 agonists

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A 63-year-old man with type 2 diabetes was admitted to the hospital to undergo right robotic partial nephrectomy.

Novel oral glucose lowering drugs reduce adverse events in type 2 diabetes

Novel oral glucose lowering drugs reduce adverse events in type 2 diabetes

Researchers observed a reduced risk of all-cause mortality and CVD with dapagliflozin and a lower risk of mortality with dipeptidyl-peptidase-4 inhibitors.

A differing opinion on the ACP's new diabetes treatment guidelines

A differing opinion on the ACP's new diabetes treatment guidelines

Pharmacotherapy and combination therapy may be a better alternative to the ACP's diabetes treatment guidelines.

Accuracy of prediabetes screening tests is low

Accuracy of prediabetes screening tests is low

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Fasting glucose is specific but not sensitive, and HbA1c is neither sensitive nor specific.

Mortality risk increased in type 2 diabetes with depression or anxiety

Mortality risk increased in type 2 diabetes with depression or anxiety

Men with diabetes, but not women, had excess mortality risk associated with depression and anxiety.

Updated guideline for oral pharmacologic treatment of type 2 diabetes

Updated guideline for oral pharmacologic treatment of type 2 diabetes

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The ACP has updated the 2012 guideline to provide clinical recommendations of oral pharmacologic treatment of type 2 diabetes.

Sex hormone-binding globulin and estradiol associated with type 2 diabetes in women

Sex hormone-binding globulin and estradiol associated with type 2 diabetes in women

Women may have a higher risk of type 2 diabetes with low levels of sex hormone-binding globulin and high levels of total estradiol.

Early intensification of diabetes therapy after metformin failure is beneficial

Early intensification of diabetes therapy after metformin failure is beneficial

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Intensification of therapy within 6 months of metformin monotherapy failure resulted in rapid attainment of A1c goals.

Oily fish consumption may lower diabetic retinopathy risk in type 2 diabetes

Oily fish consumption may lower diabetic retinopathy risk in type 2 diabetes

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A target intake of at least 500 mg/d is recommended to combat sight-threatening diabetic retinopathy.

Drug may slow renal disease progression in type 2 diabetes

Drug may slow renal disease progression in type 2 diabetes

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Canagliflozin 100 mg or 300 mg slowed kidney decline compared with glimepiride.

Adlyxin approved for type 2 diabetes

Adlyxin approved for type 2 diabetes

The once-daily injection works to improve glycemic control.

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