Vaccine Information Center Archive

FDA approves Heplisav-B vaccine for hepatitis B treatment

The Food and Drug Administration (FDA) has approved Heplisav-B for the prevention of infection caused by all known subtypes of hepatitis B virus.

Reduced effectiveness of last season's flu vaccine traced to mutation in chicken eggs

New virus mutations make antibody binding difficult as mismatches in vaccines and viruses emerge.

Proposed pneumonia vaccine provides universal pneumococcal disease prevention

A pneumonia vaccine under development provides the most comprehensive coverage to date and alleviates antimicrobial concerns.

Vaccination coverage remains above 90% for infants

Infants aged 19-35 months had vaccination rates above 90%.

CDC committee recommends new shingles vaccine

CDC voted for Shingrix over Zostavax as herpes zoster vaccine of choice

Module created to improve adult vaccination rates

The AMA STEPS Forward module helps health care professionals save time by creating a team-based approach for an adult immunization program.

No evidence that the influenza vaccine causes VTE

In the 1 to 10 days after flu vaccine administration, there was no increased risk for VTE.

Positive mood associated with enhanced responses to influenza vaccination

Greater positive mood significantly predicted greater antibody responses to the influenza vaccination.

Tdap vaccination during pregnancy protects infants from pertussis

With a continuing resurgence in pertussis, efforts should focus on maximizing Tdap uptake among pregnant women.

Half of adults with work-related asthma receive pneumococcal vaccination

The researchers found that 42% of the estimated 12 million ever-employed adults with current asthma had received a pneumococcal vaccine.

CDC releases updated influenza vaccine recommendations for 2017-2018

The Advisory Committee on Immunization Practices has released the guidelines for the 2017-2018 season.

AAP: Hepatitis B vaccine should be given within first 24 hours of life

The American Academy of Pediatrics recommends that the first dose of the hepatitis B vaccine should be given within the first 24 hours of life.

Anti-vaccine information during pregnancy could delay infant immunization

Information about vaccines received during pregnancy could influence infant immunization.

Live attenuated influenza vaccine ineffective in children during 2015-2016 season

The live attenuated vaccine was ineffective among children between 2 and 17 years of age during the 2015-2016 season.

Previous maternal influenza vaccine does not weaken newborn benefit

Researchers found that in a cohort of pregnant women, receipt of influenza vaccine the previous year predicts higher baseline antibody titers and decreased peak antibody responses against all influenza strains.

12.9 million infants worldwide not vaccinated in 2016: A WHO report

Nearly 1 in 10 infants did not receive any vaccinations in 2016, according to the World Health Organization.

CDC urges measles vaccine for European travelers

Most measles cases in the United States are the result of international travel.

Clinician communication affects parental decision-making with pediatric influenza vaccine

About half of patients accepted influenza vaccination for their child if the clinician used a presumptive vs participatory initiation format.

Injectable antiretroviral therapy for as HIV effective as oral medications

The investigators found that after 32 weeks, HIV remained suppressed in 91% percent of those taking the drugs orally, 94% of those receiving monthly injections, and 95% of patients receiving injections every two months.

CDC: 101 influenza deaths in children reported for 2016-17

A total of 101 influenza-related deaths occurred among children throughout the 2016-17 flu season.

Hepatitis B vaccine reduces risk of non-Hodgkin lymphoma in adolescents

The universal vaccination against hepatitis B virus infection prevented non-Hodgkin lymphoma in adolescents.

Maternal antibodies inhibit antigenic responses to vaccines in infants

Vaccines given shortly after birth demonstrated a strong inhibitory response to maternal antibodies.

Updated meningococcal vaccine guidelines reflect more dosing options

The Advisory Committee on Immunization Practices released updated guidelines to include recommendations for the 3-dose formulation of serogroup B meningococcal vaccine.

CDC finalizes cholera vaccine recommendation for international travelers

Cholera, an acute, diarrheal illness, is spread by drinking water or eating food that is contaminated with cholera bacteria.

HPV vaccine effective against genital warts in 2 doses

The researchers found that 2 doses of the HPV vaccine were just as protective as 3 doses.

2017 Adult immunization schedule released by the CDC

The ACIP has released the 2017 recommended immunization schedule for adults.

CDC: Influenza vaccine rate low this season

Forty percent of people have reported receiving the flu vaccine thus far, including 37% of children.

CDC approves HPV vaccine in 2 doses for preteens

Children younger than 15 may be given 2 HPV vaccine doses instead of 3, and the shots should be spaced at least 6 months apart.

Addressing parental vaccine concerns: AAP provides guidance for clinicians

The AAP has released a report to help clinicians address the concerns of parents who are hesitant about their children's vaccination.

Mumps outbreak controlled by third dose of MMR vaccine

A third dose of the MMR vaccine should be administered in cases of a mumps outbreak.

Concomitant vaccine administration may increase febrile seizure risk

Children who receive the influenza vaccine at the same time as PCV or a DTaP-containing vaccine have an increased risk for febrile seizure.

Predicting viral mutations may improve flu vaccine efficacy

Natural viral mutations ensure that the seasonal flu vaccine must be updated on a yearly basis.

Delayed immunizations, breastfeeding over age 1 may increase risk for caries

Researchers identify new risk factors for caries in young children.

Vaccines administered in the morning may be more effective

Vaccines administered between 9 and 11 AM showed a significant increase in patients' antibody concentration

Vaccine refusal key factor in measles, pertussis risk

Of 970 measles cases studied, 574 were eligible to receive the vaccine but chose not to.

Increased use of Gardasil 9 for HPV prevention would reduce cervical cancer rates, healthcare costs

The new vaccine protects against 9 types of HPV and 5 cancer-causing strains.

ASCO recommendations aim to increase HPV vaccination rates

The American Society of Clinical Oncology has released its recommendations to help improve rates of HPV vaccination worldwide.

ACOG recommendations on immunization integration in OB/GYN practices

Women's health practitioners should offer vaccinations for a wide range of common, preventable diseases.

Second dose of varicella vaccine boots vaccine efficacy

A second inoculation administered between 4 and 6 years of age is nearly 100% effective in preventing varicella.

ACIP recommends minor changes in flu vaccination practices

An ACIP panel recommended adding live-attenuated influenza vaccination as an option for individuals with egg allergy of any severity.

CDC reports nearly 60% efficacy for influenza vaccine

The ACIP announced the latest vaccine effectiveness percentages at their February 24th meeting.

HPV prevalence declines since introduction of vaccine in young females

Data collected between 2009 and 2012 show a significant decline in cases of HPV in females aged 14-19 and 20-24.

CDC urges rapid antiviral treatment of very ill and high-risk patients suspected of having influenza

Cases of both influenza A and influenza B have been reported since October 2015.

Tdap vaccine moderately effective for 1 year after vaccination

The Tdap vaccine for adolescents provides moderate protection for 1 year after vaccination, after which efficacy declines.

2016 Recommended adult immunization schedule published by ACIP

The ACIP has released the Recommended Adult Immunization Schedule: United States, 2016, available from the Annals of Internal Medicine and the CDC.

2016 Child and adolescent immunization schedules available

The American Academy of Pediatrics has approved the 2016 immunization schedule for children and adolescents.

Influenza vaccine may reduce all-cause mortality rates in patients with heart failure

Patients with heart failure who receive the influenza vaccine may have a lower risk for all-cause mortality compared with those who do not get the vaccine.

FDA approves adjuvant flu vaccine for use in the elderly

The FDA has approved Fluad, a trivalent flu vaccine with the adjuvant MF59, for use in patients aged 65 and older.

Parents make vaccination decisions before pregnancy

According to data presented at the Academy of Pediatrics National Conference and Exhibition, nearly 75% of parents decide on child vaccination preferences before becoming pregnant.

Multidisciplinary team launches new HIV vaccine initiative

Scientists from 22 institutions are launching a new research initiative with the goal of taking a new HIV vaccine through human trials in the next 5 years.

Male adolescents not receiving HPV vaccine with other inoculations

A variety of factors have led to low rates of teenage boys being vaccinated for the human papillomavirus (HPV), said a report published in Pediatrics.

High number of U.S. children remain unvaccinated against measles

Due to a dip in the number of vaccinated individuals, almost a quarter of children under the age of 3 are currently susceptible to the measles.

Influenza vaccine can prevent pneumonia hospitalizations

The influenza vaccine may be able to prevent approximately 57% of hospitalizations due to influenza pneumonia.

Egg-free influenza vaccine now available

The makers of the egg-free flu vaccine, Flublok, have announced that it is now available nationwide.

New vaccines help reduce respiratory, diarrhea-related hospitalizations

The introduction of pneumococcal conjugate and rotavirus vaccines has helped to reduce hospitalizations from respiratory infections and diarrhea.

Flu, pneumococcal vaccines recommended by CDC, NFID

Clinicians are advised to lead by example and encourage all patients to get their annual influenza vaccine.

AAP calls for mandatory flu vaccines for children, health care workers

The American Academy of Pediatrics recommends that flu vaccines should be mandatory for children and health care workers.

At age 50, herpes zoster vaccine not cost-effective

For every 1,000 people aged 50 years that get the vaccine, only 25 cases of herpes zoster are prevented.

Children vaccination rates are high in U.S., says CDC

On average, 94% of children entering kindergarten received vaccinations.

Children with HIV may lack measles, mumps, rubella immunity

Children with HIV may not have adequate immunity against measles, mumps, and rubella, even after vaccination.

Nursing home residents should receive annual flu vaccine

A new study provides evidence that yearly influenza vaccination benefited residents of nursing homes.

HPV vaccination is lagging among U.S. adolescents

Approximately 40% of girls and 60% of boys aged 13 to 17 have not received the HPV vaccine.

Poll indicates many people are unaware of hepatitis B vaccine

More than half of Americans polled were unsure or unaware of the existence of a hepatitis B vaccine.

Genetic makeup influences HIV vaccine efficacy

Researchers may be able to make HIV vaccines that are effective for specific genetic makeups.

One and two doses of HPV-16/18 vaccine as effective as three

The Cervarix vaccine may be as effective in one or two doses as it is with three.

Sequence of shots may play role in effective HIV vaccine

Series of immunizations might encourage HIV-fighting antibodies.

Decreased flu vaccine efficacy due to differing strains

The strain of H3N2 used in last year's flu vaccine differed from the circulating strain.

Intradermal HBV vaccine safe, effective for intramuscular nonresponders

No reports of adverse events with intradermal recombinant HBsAg-based vaccine.

Many college students unaware of human papillomavirus risks

In survey, more than half didn't get vaccinated; many were unaware of risk

Provider intervention may not ease maternal caution to vaccines

Vaccine adherence didn't increase with a provider-targeted intervention; personal medical and belief exemption rates tended to overlap in California.

Prioritize HPV, meningitis, Tdap and MMR vaccines in 2015

New HPV and meningitis B vaccines offer better protection for adolescents.

Patients' cultural, religious backgrounds complicate HPV vaccine adherence

While not statistically significant, participants who noted they had received the HPV vaccine also reported that they used condoms without fail at every sexual encounter.

Reminder system improves human papillomavirus vaccine adherence

The prompted cohort was significantly more likely to complete the vaccine series in a timely manner compared with the unprompted cohort.

Measles depletes immune system up to three years post-infection

Children's immune systems appeared to be weakened for as long as 28 months following a measles infection, during which time they were at increased risk for death from a viral or bacterial disease

Tdap vaccine effectiveness may wane over time in preteens

The CDC does not recommend any shift in vaccine protocols at this time.

Investigational meningococcal vaccine may protect patients during outbreak

In the target population, 89.1% coverage with the two-dose vaccination series was obtained through May 14, 2014.

Experimental microneedle patch may be game changer for vaccine delivery

A recently completed study on the patch found that it produced a strong immune response to the measles virus in rhesus macaques with no adverse effects or health issues.

More evidence debunks measles vaccine, autism link

Finding held true even for children at risk for the developmental disorder

Subcutaneous measles vaccine superior to aerosolized vaccine

At day 91, 85.4% of children in the aerosol group and 94.6% in the subcutaneous group were seropositive.

Ebola vaccine trials start in West Africa

Roughly 6,000 health workers will get shots in country hit hard by current outbreak

Poll: More Americans favor vaccination

Survey results indicate that more people feel positively toward childhood vaccination in the wake of the measles outbreak.

Vaccine offers some protection for hepatitis E

Hepatitis E vaccine offers nearly five years of protection. Long-term efficacy still needs to be assessed.

Despite risk, many providers yield to parental vaccine delay requests

While most providers believe that veering from the recommended vaccine schedule is risky, they often agree to parents' wishes.

Centralized reminder system aids vaccination outreach

Centralized notification system might be more effective than messages from health care provider offices.

Biggest rise in measles cases reported in Illinois

The majority of patients who have gotten the measles in the current outbreak were unvaccinated.

Sexually transmitted infection rates similar among HPV-vaccinated, unvaccinated girls

There was a nearly identical increase in STIs among girls who received the HPV vaccine and girls who did not.

Flu vaccine rates low among nursing home workers

More education is needed to increase influenza vaccination rates among nursing home workers.

Measles cases surge in 2015

The spike in measles cases stemmed from an outbreak at Disney theme parks in December 2014.

Updates to U.S. childhood, adolescent vaccine schedule released

Changes in the 2015 childhood and adolescent immunization schedule include column changes to reflect the availability of influenza vaccines.

Meningococcal disease vaccine earns FDA approval

After vaccination, 62% to 88% of patients treated with the vaccine had antibodies in their blood that killed three different N. meningitidis serogroup B strains.

Only half of U.S. girls receive timely HPV vaccine

Almost half of American girls receive the HPV vaccine after the recommended age.

Novel combination therapy effective in kids with latent tuberculosis infection

88.1% of the participants in the rifapentine and isoniazid group completed treatment compared with 80.9% of participants assigned to the isoniazid-only group.

Flu vaccine only 23% effective this season

Most years, the effectiveness of the flu vaccine ranges from 10% to 60%.

Clinician education needed to improve HPV4 vaccine rate for young male adolescents in primary care

In a survey conducted by the Advisory Committee on Immunization Practices (ACIP), 33% of clinicians routinely recommend the HPV4 vaccine to 11- and 12-year-old males.

HPV vaccine not associated with increased multiple sclerosis risk

In primary and secondary analyses, vaccination was not associated with an increased risk of multiple sclerosis or other demyelinating diseases.

Flu-related outpatient visits increase this season

The proportion of outpatient visits for flu-like symptoms rose nearly 4% by the end of December 2014.

No link between psoriasis, increased herpes zoster risk

Patients with certain autoimmune diseases have a higher risk for varicella zoster infection, but the rates were not significant among patients with psoriasis.

Peramivir earns FDA approval to ease flu symptoms in adults

Patients given paramivir had flu symptoms ease 21 hours sooner compared with patients left untreated.

High-dose flu vaccine better for seniors in nursing homes

Stronger improvement in the immune response was seen in frail senior patients living in nursing homes who received a high-dose flu vaccine.

Less than 50% of Americans received their flu shot so far this year

CDC officials are urging the public to get the flu vaccine even though it may not be as effective against the mutated H3N2 strain.

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