Moderate drinking curbs CV risk in diabetes

Cardiovascular benefits observed for moderate alcohol consumption, but risk increases with heavy consumption.

Drinking wine reduces CV risk in diabetes
Drinking wine reduces CV risk in diabetes

HealthDay News -- Moderate alcohol intake, particularly wine consumption, is associated with reduced risks of cardiovascular events in patients with type 2 diabetes, according to research published online in Diabetes Care.

Juuso I. Blomster, MD, of the University of Turku in Finland, and colleagues investigated the effects of alcohol use on cardiovascular health for participants in the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified-Release Controlled Evaluation (ADVANCE) trial.

Compared with those who reported no alcohol consumption, patients with diabetes who drank alcohol moderately had fewer cardiovascular events during a median five-year follow-up period, including cardiovascular death, myocardial infarction and stroke (adjusted hazard ratio 0.83; 95% CI: 0.72 to 0.95; P=0.008).

Patients who drank moderately also had fewer microvascular complications, including new or worsening nephropathy or retinopathy (aHR, 0.85; 95% CI: 0.73 to 0.99; P=0.03); and lower all-cause mortality (aHR, 0.87; 95% CI: 0.75 to 1.00; P=0.05). Greater benefits were observed in participants who drank mostly wine.

Compared with patients who reported no alcohol consumption, those who reported heavy alcohol use had dose-dependent increased risks of cardiovascular events and all-cause mortality.

"In patients with type 2 diabetes, moderate alcohol use, particularly wine consumption, is associated with reduced risks of cardiovascular events and all-cause mortality," the researchers concluded.

Several researchers report financial ties to Servier, which contributed funding to the ADVANCE study.

References

  1. Blomster JI et al. Diabetes Care. 2014;doi:10.2337/dc13-2727.
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