Web Exclusives

No evidence that the influenza vaccine causes VTE

No evidence that the influenza vaccine causes VTE

In the 1 to 10 days after flu vaccine administration, there was no increased risk for VTE.

Postoperative mortality lower among patients treated by female surgeons

Postoperative mortality lower among patients treated by female surgeons

Fewer patients treated by female surgeons died, were readmitted to the hospital, or had complications within 30 days of surgery.

Positive mood associated with enhanced responses to influenza vaccination

Positive mood associated with enhanced responses to influenza vaccination

Greater positive mood significantly predicted greater antibody responses to the influenza vaccination.

AAP releases list of 5 unnecessary endocrine-related tests

AAP releases list of 5 unnecessary endocrine-related tests

The AAP Section for Endocrinology compiled the list of tests for height and puberty, which should prompt careful discussion between parents and physicians.

FDA approves glucose monitoring system which eliminates fingerstick testing

FDA approves glucose monitoring system which eliminates fingerstick testing

The system uses a small sensor implanted below the skin and a mobile reader to continuously monitor blood glucose.

Tdap vaccination during pregnancy protects infants from pertussis

Tdap vaccination during pregnancy protects infants from pertussis

With a continuing resurgence in pertussis, efforts should focus on maximizing Tdap uptake among pregnant women.

USPSTF recommends skin cancer prevention care to begin at age 6 months

USPSTF recommends skin cancer prevention care to begin at age 6 months

The USPSTF has released updated recommendations on skin cancer counseling and self-examination for adults with fair skin.

Gastroesophageal adenocarcinoma patients benefit from adjuvant chemotherapy

Gastroesophageal adenocarcinoma patients benefit from adjuvant chemotherapy

The researchers found that patients receiving adjuvant chemotherapy for gastroesophageal adenocarcinoma were younger, more likely to have advanced disease, and had shorter postoperative inpatient stays.

Physical and psychological coping skills associated with symptom severity in IBS

Physical and psychological coping skills associated with symptom severity in IBS

The association is partially mediated by levels of anxiety and depressive symptoms.

Colonoscopy rates improve from patient navigators, provider reminders

Colonoscopy rates improve from patient navigators, provider reminders

Patient-level interventions include changes to invitation, giving results or follow-up appointments, and patient navigators, and provider-level interventions include reminders or performance data.

Longer hospital stay linked to low health literacy

Longer hospital stay linked to low health literacy

Low health literacy is associated with a longer hospital length of stay in general medicine patients.

Half of adults with work-related asthma receive pneumococcal vaccination

Half of adults with work-related asthma receive pneumococcal vaccination

The researchers found that 42% of the estimated 12 million ever-employed adults with current asthma had received a pneumococcal vaccine.

Longer anesthesia duration linked to increased surgical complications

Longer anesthesia duration linked to increased surgical complications

Among patients undergoing microvascular reconstruction of the head and neck, increased anesthesia duration is associated with higher rates of complications.

National PA Week 2017 celebrates during the profession's 50th anniversary

National PA Week 2017 celebrates during the profession's 50th anniversary

More than 115,500 PAs will celebrate their contributions to healthcare during National PA Week.

Non-vitamin K oral anticoagulants with other medications increase bleeding risk in A-Fib

Non-vitamin K oral anticoagulants with other medications increase bleeding risk in A-Fib

The researchers found that concurrent use of amiodarone, fluconazole, rifampin, and phenytoin was associated with increased risk of major bleeding compared with the use of NOACs alone.

AAPA: Wage gap remains between female and male PAs

AAPA: Wage gap remains between female and male PAs

Although the disparity has improved, female PAs are still paid 11% less than men.

Mid-adulthood hypertension linked to dementia risk in women

Mid-adulthood hypertension linked to dementia risk in women

Among women, but not men, mid-adulthood hypertension correlated with a 65% increased dementia risk.

Increased cancer risk found in rheumatoid arthritis patients with VTE

Increased cancer risk found in rheumatoid arthritis patients with VTE

VTE and cancer are the result of inflammation and immunological dysfunctions associated with RA.

Chronic pain management in HIV: Updated recommendations

Chronic pain management in HIV: Updated recommendations

The HIV Medicine Association of the Infectious Disease Society of America recommends that people living with HIV be screened for pain and offered both nonpharmacologic and pharmacologic treatment options.

Regular, leisure exercise may reduce incidence of depression

Regular, leisure exercise may reduce incidence of depression

A correlation was found between undertaking regular leisure-time exercise and reduced incidence of future depression but not anxiety.

Single-tablet HIV treatment superior to standard therapy

Single-tablet HIV treatment superior to standard therapy

Virological response, efficacy, noninferiority, and tolerability were tested for bictegravir, emtricitabine, and tenofovir alafenamide in patients with HIV.

Most adolescents with ADHD have indifferent attitudes toward medication

Most adolescents with ADHD have indifferent attitudes toward medication

A majority of study participants also reported that they frequently skip doses of ADHD medication.

ACP calls for firearm policy after Las Vegas shooting

ACP calls for firearm policy after Las Vegas shooting

The ACP emphasizes the need for an "assault" weapons ban after the mass shooting in Las Vegas.

Aspirin discontinuation increases risk of cardiovascular events

Aspirin discontinuation increases risk of cardiovascular events

Patients who discontinued aspirin use experience a higher risk of cardiovascular events.

Smartphone apps may improve symptoms in patients with depression

Smartphone apps may improve symptoms in patients with depression

Advancements in smartphone technology may present an opportunity to help patients manage depressive symptoms.

Off-label ketamine beneficial for patients with refractory mood disorders

Off-label ketamine beneficial for patients with refractory mood disorders

Patient selection is key to optimizing the risk-to-benefit ratio of ketamine therapy.

Sleep disturbance in psoriasis leads to psychological and physical predictors

Sleep disturbance in psoriasis leads to psychological and physical predictors

Sleep complaints among individuals with psoriasis warrant greater clinical attention, as they have a greater chance for developing obstructive sleep apnea.

Psoriasis patients have an increased risk of alcohol-related mortality

Psoriasis patients have an increased risk of alcohol-related mortality

Patients with psoriasis have a greater risk of mortality due to alcohol-related causes, including alcoholic liver disease, fibrosis and cirrhosis of the liver, and mental and behavioral disorders.

Evidence finds link between antidepressant drug use and type 2 diabetes

Evidence finds link between antidepressant drug use and type 2 diabetes

After the inclusion of recent negative studies, a statistically significant association between AD use and diabetes was observed.

Secukinumab well-tolerated in patients with scalp psoriasis

Secukinumab well-tolerated in patients with scalp psoriasis

This study shows that more than 50% of patients can expect a 90% or greater improvement in scalp psoriasis within 12 weeks.

FDA approves Opdivo for treatment of hepatocellular carcinoma

FDA approves Opdivo for treatment of hepatocellular carcinoma

The FDA has approved Opdivo (nivolumab) injection for the treatment of patients with HCC who have been previously treated with sorafenib.

CDC: US cases of STDs exceed 2 million

CDC: US cases of STDs exceed 2 million

According to the report, 1.6 million cases were chlamydia, and there were 470,000 cases of gonorrhea and almost 28,000 primary and secondary syphilis cases.

Notification rates of HIV diagnoses increased in 16 European countries

Notification rates of HIV diagnoses increased in 16 European countries

In 16 countries, notification rates for new HIV diagnoses in older adults increased significantly, clustering in central and eastern European countries.

Combating the hepatitis A outbreak in San Diego

Combating the hepatitis A outbreak in San Diego

The 3-part plan to halt the outbreak of hepatitis A focuses on immunization, sanitation and education with most of the efforts focused on the homeless population who are the most at-risk population.

Hepatocellular carcinoma risk unclear after hepatitis C treatment

Hepatocellular carcinoma risk unclear after hepatitis C treatment

The results show no evidence to support a hypothesis of differential impact of interferon and direct-acting antiviral-based cure on risk for HCC occurrence and recurrence.

Clinician characteristics predict low-value back and headache imaging

Clinician characteristics predict low-value back and headache imaging

Clinician predictors of low-value imaging include ordering low-value imaging on a prior patient, high rates of low-value imaging in another clinical scenario, and ownership of imaging equipment.

Gastric bypass surgery effective for weight loss, diabetes prevention for 12 years

Gastric bypass surgery effective for weight loss, diabetes prevention for 12 years

The 12-year results show that Roux-en-Y gastric bypass offered long-term durability of weight loss and was associated with fewer obesity-related coexisting conditions compared with those who did not have the surgery.

Once-daily HIV tablet safe for children

Once-daily HIV tablet safe for children

Elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide was well tolerated in children and maintained high virological suppression.

Arthroscopic rotator cuff repair: comparing postoperative treatment options for pain

Arthroscopic rotator cuff repair: comparing postoperative treatment options for pain

No significant differences were found in pain management for arthroscopic rotator cuff repair between use of an abduction brace and antrotation sling.

US adults affected by ADHD not properly treated

US adults affected by ADHD not properly treated

There is an unmet need for better treatment to manage symptom burden among US adults with ADHD.

Pediatric inflammatory bowel disease increases cancer risk in adulthood

Pediatric inflammatory bowel disease increases cancer risk in adulthood

Patients with childhood-onset IBD have an increased risk of cancer, especially gastrointestinal cancers, lymphoid neoplasms, and skin cancer,

Discontinuation of antidepressants before 1 year may increase relapse risk in patients with anxiety

Discontinuation of antidepressants before 1 year may increase relapse risk in patients with anxiety

Antidepressant discontinuation increased the odds of relapse compared with continued therapy.

Oral isotretinoin better than topical treatment for warts

Oral isotretinoin better than topical treatment for warts

Oral isotretinoin showed the best response in cases of facial warts

Steroid treatment effective for carpal tunnel syndrome

Steroid treatment effective for carpal tunnel syndrome

The researchers found that four weeks after treatment there was significant improvement in Boston Carpal Tunnel Questionnaire scores.

New biochemical bone assessment predicts fracture risk in children

New biochemical bone assessment predicts fracture risk in children

The FSI proved to be at least as effective in predicting fracture risk in children as femoral and total body BMD.

FDA approves Adzenys ER for ADHD treatment

FDA approves Adzenys ER for ADHD treatment

The FDA has approved Adzenys ER extended-release oral suspension ADHD treatment for patients 6 years and older.

Cervical cancer screening: recommendations from the USPSTF

Cervical cancer screening: recommendations from the USPSTF

The major change includes screening with hrHPV testing alone as an alternative to cytology screening alone starting at age 30 years.

Venous thromboembolism risk strongly linked to height in men and women

Venous thromboembolism risk strongly linked to height in men and women

Researchers found a strong association between VTE and height using sibling pair analysis.

Weekend hospital admissions linked to higher mortality rate

Weekend hospital admissions linked to higher mortality rate

Patients admitted to the ER during weekends as opposed to weekdays have a higher mortality rate.

Suicide attempt risk not associated with ADHD treatment

Suicide attempt risk not associated with ADHD treatment

There does not appear to be an association between methylphenidate hydrochloride treatment for ADHD and suicide attempts.

Vitamin D supplements may improve bone health in HIV-infected youth

Vitamin D supplements may improve bone health in HIV-infected youth

High-dose vitamin D supplements improve bone mineral density in youth with HIV.

Clinical practice guideline for antiretroviral therapy in pregnant women with HIV

Clinical practice guideline for antiretroviral therapy in pregnant women with HIV

Alternative treatments should be offered to pregnant women with HIV instead of tenofovir or emtricitabine.

FDA to review novel investigational treatment for ADHD

FDA to review novel investigational treatment for ADHD

Sunovion has submitted a New Drug Application for dasotraline, a new treatment for ADHD.

USPSTF recommends screening for amblyopia in all children aged 3 to 5 years

USPSTF recommends screening for amblyopia in all children aged 3 to 5 years

The USPSTF recommends that children aged 3 to 5 years undergo vision screening at least once to detect amblyopia or its risk factors.

Smartphone-based electronic reader reliable for point-of-care tests in HIV and T pallidum infections

Smartphone-based electronic reader reliable for point-of-care tests in HIV and T pallidum infections

The findings shed new light on the applicability of smartphone-based electronic readers in point-of-care testing.

Hormone replacement therapy for menopause not associated with increased mortality risk

Hormone replacement therapy for menopause not associated with increased mortality risk

The researchers found no long-term increase in either all-cause or cause-specific mortality among women who received hormone therapy for up to 5.6 years or 7.2 years, depending on the type of therapy.

2017-2018 recommendations for pediatric influenza vaccination

2017-2018 recommendations for pediatric influenza vaccination

The guidelines include a strong recommendation for annual seasonal influenza immunization for everyone 6 months and older.

Colon cleansing regimens in inflammatory bowel disease: a review

Colon cleansing regimens in inflammatory bowel disease: a review

A PEG low-volume regimen is similar to a PEG high-volume regimen for colon cleansing in patients with IBS.

GERD may be associated with long-term risk of pneumonia

GERD may be associated with long-term risk of pneumonia

Incidence of pneumonia was higher among patients with GERD compared with matched controls.

Vitamin D supplements reduce depressive symptoms, cardiac events in moderate to severe depression

Vitamin D supplements reduce depressive symptoms, cardiac events in moderate to severe depression

In patients with depressive symptoms, vitamin D deficiency with no additional supplements had the highest depressive score at 6 months and shortest cardiac event-free survival.

Many avoidable emergency department visits include mental health and dental conditions

Many avoidable emergency department visits include mental health and dental conditions

A significant number of avoidable visits to the emergency department are related to mental health and dental conditions.

Breastfeeding associated with a lower risk of endometriosis

Breastfeeding associated with a lower risk of endometriosis

Duration of total and exclusive breastfeeding was significantly associated with a decreased risk of endometriosis.

Psychosis not associated with worse outcomes in bipolar disorder

Psychosis not associated with worse outcomes in bipolar disorder

Psychosis was not associated with worse clinical or functional outcomes in patients with bipolar disorder.

Coffee consumption associated with reduced liver cancer risk, no link to biliary tract cancer

Coffee consumption associated with reduced liver cancer risk, no link to biliary tract cancer

No significant association was observed between coffee consumption and risk of biliary tract cancer, but there was evidence of an inverse correlation between coffee consumption and liver cancer risk.

Managing hypertension in diabetes: a position statement from the ADA

Managing hypertension in diabetes: a position statement from the ADA

The statement includes advances in care since the ADA's last position statement was published in 2003.

Mediterranean diet, antioxidant supplements beneficial for non-alcoholic fatty liver disease

Mediterranean diet, antioxidant supplements beneficial for non-alcoholic fatty liver disease

A Mediterranean diet with antioxidant supplementation contributes to improving lipid profile and insulin sensitivity parameters in patients with non-alcoholic fatty liver disease.

Smoking may be a risk factor for psoriasis

Smoking may be a risk factor for psoriasis

Researchers observed a positive correlation between the amount and duration of smoking and the occurrence of psoriasis.

Natriuretic peptide-guided therapy does not improve outcomes in high-risk heart failure patients

Natriuretic peptide-guided therapy does not improve outcomes in high-risk heart failure patients

NT-proBNP-guided treatment strategy did not improve outcomes compared with a usual care strategy in high-risk patients with heart failure.

CDC releases updated influenza vaccine recommendations for 2017-2018

CDC releases updated influenza vaccine recommendations for 2017-2018

The Advisory Committee on Immunization Practices has released the guidelines for the 2017-2018 season.

Noninvasive test effective for monitoring hepatic fibrosis in psoriasis patients taking methotrexate

Noninvasive test effective for monitoring hepatic fibrosis in psoriasis patients taking methotrexate

NASH FibroSure is useful to monitor for risk of worsening fibrosis during MTX therapy.

Anti-inflammatory drug may reduce risk of cardiovascular events, lung cancer

Anti-inflammatory drug may reduce risk of cardiovascular events, lung cancer

The findings offer the first strong clinical evidence that inflammation-targeted therapy may reduce the risk of cardiovascular disease.

Updated recommendations for pediatric integrative medicine

Updated recommendations for pediatric integrative medicine

The recommendations update the AAP's original 2008 statement on complementary medicine.

Sepsis, pneumonia lead to increased risk of cardiovascular disease in men

Sepsis, pneumonia lead to increased risk of cardiovascular disease in men

Men who are admitted to the hospital with a serious infection may have an increased risk of cardiovascular disease in the years immediately following the infection.

Shorter sleep duration linked to higher diabetes risk in children

Shorter sleep duration linked to higher diabetes risk in children

Sleep duration for 1 hour longer was associated with lower BMI, fat mass, insulin resistance, and fasting glucose but had no effect on HbA1c or cardiovascular risk.

Hypoxia, increased work of breathing outweigh tachypnea, auscultatory findings in diagnosing pneumonia

Hypoxia, increased work of breathing outweigh tachypnea, auscultatory findings in diagnosing pneumonia

No single clinical observation reliably differentiates pneumonia from other causes of respiratory illness in children.

Vitamin B supplements not chemopreventive for lung cancer

Vitamin B supplements not chemopreventive for lung cancer

Vitamin B supplements are not chemopreventive and may increase cancer risk in men.

Oral corticosteroids not effective for lower respiratory tract infection

Oral corticosteroids not effective for lower respiratory tract infection

No significant effects were found from oral corticosteroid use for acute lower respiratory tract infection in adults without asthma.

Influenza A virus transmitted from swine to humans at agricultural fair

Influenza A virus transmitted from swine to humans at agricultural fair

Researchers found the H3N2 virus in swine at state fairs in Ohio and Michigan, which was transmitted to humans.

Managing high blood pressure in children: a clinical practice guideline

Managing high blood pressure in children: a clinical practice guideline

The AAP has released an updated clinical practice guideline for the diagnosis and management of high blood pressure in children.

Previous cesarean delivery increases risk of complications after hysterectomy

Previous cesarean delivery increases risk of complications after hysterectomy

Women with at least 1 previous cesarean delivery have an increased risk of complications when undergoing a hysterectomy.

Individuals born in states with high stroke mortality have increased risk of dementia

Individuals born in states with high stroke mortality have increased risk of dementia

Birth in a high stroke mortality state was associated with a significantly increased risk of dementia.

Sperm counts significantly declining in men from North America, Europe

Sperm counts significantly declining in men from North America, Europe

Western males saw the most significant sperm count decline at 52.4%.

Live attenuated influenza vaccine ineffective in children during 2015-2016 season

Live attenuated influenza vaccine ineffective in children during 2015-2016 season

The live attenuated vaccine was ineffective among children between 2 and 17 years of age during the 2015-2016 season.

Comparing anticoagulants to prevent venous thromboembolism after hip and knee arthroplasty

Comparing anticoagulants to prevent venous thromboembolism after hip and knee arthroplasty

Fondaparinux and rivaroxaban were associated with increased risk of major bleeding in patients who underwent total hip or knee arthroplasty.

Lifestyle intervention provides minimal benefit in improving glycemic control in type 2 diabetes

Lifestyle intervention provides minimal benefit in improving glycemic control in type 2 diabetes

Lifestyle interventions maintain glycemic control in patients with type 2 diabetes.

Antiemetics: a clinical practice guideline update from ASCO

Antiemetics: a clinical practice guideline update from ASCO

The updated guidelines will help clinicians prevent and manage nausea and vomiting caused by antineoplastic agents or radiation therapy in cancer patients.

Forty percent of hospitalized patients report breakdowns in care

Forty percent of hospitalized patients report breakdowns in care

Hospital patients reported breakdowns in care, which included information exchange, medications, delays in admission, team communication, providers' manner, and discharge.

Colorectal cancer mortality rates increasing in younger white adults

Colorectal cancer mortality rates increasing in younger white adults

Researchers analyzed colorectal cancer mortality rates among individuals between 20 and 54 years of age from 1970 through 2014.

Adding oats to a gluten-free diet may not affect patients with celiac disease

Adding oats to a gluten-free diet may not affect patients with celiac disease

The addition of oats to a gluten-free diet did not affect symptoms, histology, immunity, or serologic features in patients with celiac disease.

Tips for avoiding pneumonia in patients with COPD

Tips for avoiding pneumonia in patients with COPD

The COPD Foundation has released tips for patients with COPD to avoid pneumonia and exacerbations.

CTE found in high proportion of deceased football players

CTE found in high proportion of deceased football players

A new study finds compelling evidence of a strong link between chronic traumatic encephalopathy and North American football.

Occupational pesticide exposure linked to fixed airflow obstruction and chronic bronchitis

Occupational pesticide exposure linked to fixed airflow obstruction and chronic bronchitis

Results show that exposure to pesticides and herbicides is associated with fixed airflow obstruction and chronic bronchitis.

Sexually risky behavior more common in women with mental disorders than in men

Sexually risky behavior more common in women with mental disorders than in men

Women with mental illness engage in significantly more sexually risky behaviors than men, and personality risk scores are a significant predictor of total sex acts for women but not men.

Treating acute COPD exacerbations with prednisone and doxycycline

Treating acute COPD exacerbations with prednisone and doxycycline

Researchers found that doxycycline plus prednisone did not prolong the time between exacerbations in patients with COPD.

Sugar consumption linked to increased risk of mood disorders

Sugar consumption linked to increased risk of mood disorders

Research reveals an adverse effect of sugar intake from sweet foods and beverages on long-term psychological health.

Offering rapid HIV testing to patients increases overall testing rate in the emergency department

Offering rapid HIV testing to patients increases overall testing rate in the emergency department

Rapid HIV testing offered in parallel to patient-clinician consultations increases the testing rate in the emergency department.

Transcranial magnetic stimulation outcomes similar in younger and older adults with depression

Transcranial magnetic stimulation outcomes similar in younger and older adults with depression

Researchers found no difference in outcomes between older and younger adults undergoing transcranial magnetic stimulation for depression.

Human embryo editing repairs genetic mutation that causes hypertrophic cardiomyopathy

Human embryo editing repairs genetic mutation that causes hypertrophic cardiomyopathy

The gene-editing tool called CRISPR-Cas9 could have the potential to treat and prevent other genetic diseases.

Regular alcohol consumption associated with lower risk of diabetes

Regular alcohol consumption associated with lower risk of diabetes

Consumption of alcohol 3 to 4 days weekly is associated with a significantly lower risk for diabetes in men and women.

WHO releases new guidelines in response to pretreatment HIV drug resistance

WHO releases new guidelines in response to pretreatment HIV drug resistance

The new guidelines address the issue of how to manage pretreatment HIV drug resistance in countries where the prevalence of is 10% or higher.

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