Web Exclusives

Added fructose: a chief driver of type 2 diabetes?

Added fructose: a chief driver of type 2 diabetes?

Reducing the intake of added sugars may help reduce diabetes-related morbidity, researchers suggest.

Does political affiliation affect life span?

Does political affiliation affect life span?

When it came to political ideologies, 30% of conservatives and moderates died compared with 25% of liberals.

Prescription costs forcing some patients to skimp on treatment

Prescription costs forcing some patients to skimp on treatment

Although patients skimped on prescription drugs because of financial concerns at every age, patients aged 64 years or younger were more likely to do so.

Hypertension guideline adherence yields health, economic benefits

Hypertension guideline adherence yields health, economic benefits

Full implementation of the new hypertension guidelines would reduce deaths and treatment costs for patients aged 45 to 74 years with cardiovascular disease.

Eating blueberries may reduce blood pressure in postmenopausal women

Eating blueberries may reduce blood pressure in postmenopausal women

Nitric oxide levels were greater in the blueberry powder group compared with baseline levels, while no changes were observed in the control group.

Protein, probiotic combo shows promise for pediatric peanut allergy

Protein, probiotic combo shows promise for pediatric peanut allergy

A new oral therapy that combines a probiotic and peanut protein appears to be a successful immunotherapy for peanut allergy.

Chronic insomnia tied to increased hypertension risk

Chronic insomnia tied to increased hypertension risk

Patients with chronic insomnia who took longer than 14 minutes to fall asleep had a 300% higher risk of hypertension.

Diet, exercise may lower plaque build-up in coronary arteries

Diet, exercise may lower plaque build-up in coronary arteries

Intensive lifestyle modifications were associated with a decrease in atherosclerotic burden in both coronary and carotid vasculature systems.

How does the public perceive medical malpractice?

How does the public perceive medical malpractice?

A survey of Massachusetts residents concluded overwhelming public support for more transparency from providers and hospitals.

First generic esomeprazole approved by FDA

First generic esomeprazole approved by FDA

The FDA has approved esomeprazole magnesium delayed-release capsules, the first generic version of AstraZeneca's Nexium.

Updates to U.S. childhood, adolescent vaccine schedule released

Updates to U.S. childhood, adolescent vaccine schedule released

Changes in the 2015 childhood and adolescent immunization schedule include column changes to reflect the availability of influenza vaccines.

Novel combo hypertension drug gets FDA nod

Novel combo hypertension drug gets FDA nod

Perindopril arginine and amlodipine besylate may be used as initial therapy if a patient is likely to need multiple drugs to achieve their blood pressure goals.

Meningococcal disease vaccine earns FDA approval

Meningococcal disease vaccine earns FDA approval

After vaccination, 62% to 88% of patients treated with the vaccine had antibodies in their blood that killed three different N. meningitidis serogroup B strains.

Only half of U.S. girls receive timely HPV vaccine

Only half of U.S. girls receive timely HPV vaccine

Almost half of American girls receive the HPV vaccine after the recommended age.

Fishes omega-3 benefits offset mercury toxicity risk in pregnancy

Fishes omega-3 benefits offset mercury toxicity risk in pregnancy

Only children whose mothers had high levels of meat-related omega-6 fatty acids but low levels of omega-3s from fish oil had associated developmental damage.

E-cigarette vapor contains high levels of formaldehyde

E-cigarette vapor contains high levels of formaldehyde

High-voltage e-cigarettes released enough formaldehyde-containing compounds to increase a patient's lifetime risk of cancer five to 15 times higher than the risk caused by long-term smoking.

U.S. extremely premature infant survival rates increasing

U.S. extremely premature infant survival rates increasing

The largest declines in mortality were in those born at 23 or 24 weeks of gestation.

Record-high number of measles cases reported in 2014

Record-high number of measles cases reported in 2014

There were 644 new measles cases in 27 states in 2014, according to the CDC.

Patients lack proper hypoglycemia management, prevention knowledge

Patients lack proper hypoglycemia management, prevention knowledge

A majority of patients with diabetes are worried about experiencing hypoglycemia, with many being uncertain about how to manage the condition.

Secukinumab earns FDA approval for plaque psoriasis

Secukinumab earns FDA approval for plaque psoriasis

Secukinumab has been approved by the FDA for the treatment of moderate to severe plaque psoriasis in adult patients who are candidates for systemic therapy or phototherapy.

Lorcaserin savings card now available for chronic weight management

Lorcaserin savings card now available for chronic weight management

Eisai has launched a new savings card for lorcaserin (Belviq) to increase the affordability and accessibility of the weight-loss drug.

Coffee may lower melanoma risk

Coffee may lower melanoma risk

People who drank one to three cups a day had about a 10% decreased risk of melanoma compared with those who drank none at all.

Working in pairs may reduce diagnostic errors

Working in pairs may reduce diagnostic errors

Fourth-year medical students who worked in pairs ordered more accurate tests compared with students who worked independently.

Low vegetable-based protein intake may up metabolic syndrome risk

Low vegetable-based protein intake may up metabolic syndrome risk

Decreased vegetable protein intake and increased dietary acid load were associated with prevalence of metabolic syndrome.

Novel combination therapy effective in kids with latent tuberculosis infection

Novel combination therapy effective in kids with latent tuberculosis infection

88.1% of the participants in the rifapentine and isoniazid group completed treatment compared with 80.9% of participants assigned to the isoniazid-only group.

Obese patients, smokers spend more on health care each year

Obese patients, smokers spend more on health care each year

Estimated health-care expenses associated with obesity and smoking increased between 1998 and 2011 by 25% and 30%, respectively.

Are kids and teens eating too much pizza?

Are kids and teens eating too much pizza?

On days when kids and teens reported eating pizza, their overall daily total calorie consumption was higher.

Patients may be mixing medications with alcohol

Patients may be mixing medications with alcohol

Nearly 42% of patients considered current drinkers reported taking a medication that can interact with alcohol.

Unhealthy diet tied to refractory functional dyspepsia

Unhealthy diet tied to refractory functional dyspepsia

The prevalence of unhealthy dietary behaviors was higher among RFD and NRFD compared with healthy controls.

Teenage acne, melanoma link identified in women

Teenage acne, melanoma link identified in women

Among women with a history of severe teenage acne, the relative risk increased for melanoma even after adjustment for previously known risk factors.

Light therapy shows promise in treating nonspecific back pain

Light therapy shows promise in treating nonspecific back pain

Compared with the control group, the changes in pain intensity were higher in the bright light group.

Being sedentary may be worse than being obese

Being sedentary may be worse than being obese

Exercise that burns between 90 and 100 calories per day could reduce the risk of early death by 16% to 30%.

Flu vaccine only 23% effective this season

Flu vaccine only 23% effective this season

Most years, the effectiveness of the flu vaccine ranges from 10% to 60%.

OB/GYN leadership lacks gender diversity

OB/GYN leadership lacks gender diversity

Representation of women was closer to parity among residency program directors, in which women held just under half of positions.

Late, early menstruation onset age ups heart disease risk

Late, early menstruation onset age ups heart disease risk

Women who had an early or late age of menstruation onset have an increased risk for coronary heart disease, stroke and hypertension.

Hospital-acquired infections rates are falling

Hospital-acquired infections rates are falling

Decreases were seen in central-line associated bloodstream infections and surgical-site infections.

Full practice nurse practitioners linked to improved health outcomes

Full practice nurse practitioners linked to improved health outcomes

Despite a predicted shortage of primary-care providers, some states do not allow nurse practitioners to practice to the full extent of their training.

Community cardiovascular disease prevention program tied to improved heart health

Community cardiovascular disease prevention program tied to improved heart health

Improvements in hypertension, cholesterol control, and smoking cessation rates among participants enrolled in a cardiovascular disease prevention program were seen.

Southern states have lower HIV survival rates

Southern states have lower HIV survival rates

Nine southern states had a higher HIV diagnosis rate and higher proportions of patients diagnosed with HIV who were black, female, younger.

Using continuous blood glucose monitoring for type 1 diabetes management

Using continuous blood glucose monitoring for type 1 diabetes management

A 25-year-old woman newly diagnosed with type 1 diabetes presents with insidious onset of recurrent hypoglycemia and is given a CGM device.

Appetite-curbing implant earns FDA approval

Appetite-curbing implant earns FDA approval

The Maestro Rechargeable System has been approved by the FDA to treat obese patients with at least one obesity-related condition.

Does extensive hepatitis C screening help or harm?

Does extensive hepatitis C screening help or harm?

The risk-benefit profile of more widespread hepatitis C screening is not sufficiently understood, researchers suggest.

Education needed for cardiovascular risks linked to psoriasis, PsA

Education needed for cardiovascular risks linked to psoriasis, PsA

Educational programs may improve cardiovascular and metabolic risk management in patients.

Wisconsin lawmaker reintroduces medical malpractice expansion bill

Wisconsin lawmaker reintroduces medical malpractice expansion bill

While most states allow adult children and parents of adult children to sue based on a loved one's death, Wisconsin does not.

Head Start preschool program linked to better weight status in kids

Head Start preschool program linked to better weight status in kids

Obese and overweight children lost weight faster compared with the two comparison groups of children who weren't in the program.

Experts call for improved hepatitis C care

Experts call for improved hepatitis C care

Just 27% of patients with hepatitis C were in care and 15% had reported being treated or receiving treatment.

Acetaminophen use during pregnancy: is it safe?

Acetaminophen use during pregnancy: is it safe?

A meta-analysis reveals a weak association between acetaminophen use during pregnancy and the development of childhood asthma.

E-cigs may increase susceptibility to common cold, infections

E-cigs may increase susceptibility to common cold, infections

Goal was to measure devices' impact on children, researchers say

Sleeping supine may increase stillbirth risk

Sleeping supine may increase stillbirth risk

Sleep position may be additional risk for late-pregnancy stillbirth in already compromised fetus.

Novel anticoagulant Savaysa gets FDA nod

Novel anticoagulant Savaysa gets FDA nod

Savaysa (edoxaban) is indicated to treat deep vein thrombosis and pulmonary embolism and prevent stroke.

Biologic monotherapy more effective combination Tx in psoriasis patients

Biologic monotherapy more effective combination Tx in psoriasis patients

Agents in biologic monotherapy target key processes in the pathogenesis of psoriasis, therefore offering better efficacy than current biologic and systemic therapies.

High-risk HPV testing guidance released

High-risk HPV testing guidance released

The cobas HPV test detects DNA from 14 types of HPV and included types 16 and 18, which cause 70% of cervical cancers.

Hypertension management apps need better regulation

Hypertension management apps need better regulation

Nearly 14% of Google Play apps used a phone's camera to measure blood pressure without a cuff or proper validation.

Selenium, vitamin E supplements do not reduce cataract risk in men

Selenium, vitamin E supplements do not reduce cataract risk in men

Long-term selenium and vitamin E supplementation did not reduce apparently healthy male patients' risks of developing age-related cataracts.

Nutrition education ups fruit, veggie intake in patients with BRCA

Nutrition education ups fruit, veggie intake in patients with BRCA

Only the consumption of fruits and vegetables was significantly higher in the intervention group.

Earlier life adiposity tied to nonalcoholic fatty liver disease in adolescents

Earlier life adiposity tied to nonalcoholic fatty liver disease in adolescents

Adiposity at age 3 years has been linked to diagnosis and severity of hepatic steatosis in late adolescence.

Emphasize lifestyle behavior changes for patients with psoriasis

Emphasize lifestyle behavior changes for patients with psoriasis

Clinicians who treat patients with psoriasis may need additional training in lifestyle behavior modification initiatives.

Limiting alcohol, increasing veggies may reduce obesity-related cancer risk

Limiting alcohol, increasing veggies may reduce obesity-related cancer risk

Dietary advice on preventing cancer should emphasize the importance of eating a plant-based diet and restricting alcohol consumption.

HPV vaccine not associated with increased multiple sclerosis risk

HPV vaccine not associated with increased multiple sclerosis risk

In primary and secondary analyses, vaccination was not associated with an increased risk of multiple sclerosis or other demyelinating diseases.

Rates of assisted reproductive technology complications are low

Rates of assisted reproductive technology complications are low

The most commonly reported patient complications were ovarian hyperstimulation syndrome and hospitalization.

Flu-related outpatient visits increase this season

Flu-related outpatient visits increase this season

The proportion of outpatient visits for flu-like symptoms rose nearly 4% by the end of December 2014.

Whole grains linked to lower mortality, cardiovascular disease risk

Whole grains linked to lower mortality, cardiovascular disease risk

One-third fewer patients died among the group that reported consuming the most whole grains per day.

Preeclampsia-autism connection found

Preeclampsia-autism connection found

The children of mothers who had preeclampsia during pregnancy are more likely to develop autism spectrum disorder.

Non-TNF blocker for colitis, Crohn disease

Non-TNF blocker for colitis, Crohn disease

Entyvio can be used to treat ulcerative colitis and Crohn disease in adults who did not have success with other treatments.

Low chlamydia, gonorrhea rates may suggest overscreening

Low chlamydia, gonorrhea rates may suggest overscreening

Of the women, 21% of women experienced overscreening, and were all menopausal, had a hysterectomy, or were aged older than 40 years.

Asthma, COPD linked with more inflammatory bowel disease

Asthma, COPD linked with more inflammatory bowel disease

People with airway diseases are more likely to have inflammatory bowel disease.

Medicare penalizes hospitals for preventable medical errors

Medicare penalizes hospitals for preventable medical errors

Hospitals that were penalized for high preventable error rates will have their Medicare payments lowered by 1% over the fiscal year.

No link between psoriasis, increased herpes zoster risk

No link between psoriasis, increased herpes zoster risk

Patients with certain autoimmune diseases have a higher risk for varicella zoster infection, but the rates were not significant among patients with psoriasis.

Can exercise help patients with Parkinson disease?

Can exercise help patients with Parkinson disease?

Minimally supervised exercise programs benefited patients with milder Parkinson disease.

Glitazones in bladder cancer

Glitazones in bladder cancer

Pioglitazone was not linked to bladder cancer in an extensive analysis.

Gender impacts opioid-related adverse effects in kids

Gender impacts opioid-related adverse effects in kids

For girls, but not boys, there was a significant morphine effect for postoperative nausea and vomiting and prolonged post-anesthesia recovery unit stay.

Diet, alcohol consumption effect psoriasis symptoms

Diet, alcohol consumption effect psoriasis symptoms

Overweight and obese psoriasis patients should to lose weight and increase physical activity as a way to improve psoriasis symptoms.

Digoxin for A-fib ups deaths, hospitalizations

Digoxin for A-fib ups deaths, hospitalizations

In patients with atrial fibrillation but no heart failure, digoxin increases the risk of death and hospitalization.

High fiber intake may lower kidney stone risk in postmenopausal women

High fiber intake may lower kidney stone risk in postmenopausal women

There were no significant protective effects noted for fiber, fruit, or vegetable intake on the risk of kidney stone recurrence in women with a history of stones.

Bacterial skin/skin structure treatment

Bacterial skin/skin structure treatment

Dalvance is used to treat acute ­bacterial skin and skin structure infections (ABSSSI) that have been caused by certain susceptible Gram-positive organisms.

Daily activity staves off Parkinson disease

Daily activity staves off Parkinson disease

Moderate, daily physical activity has been linked to a decreased risk of Parkinson disease.

Weight loss strategies yield similar results in men, women

Weight loss strategies yield similar results in men, women

Although men lost more weight than women, the evidence does not indicate that weight loss strategies should differ according to sex.

Alkaline phosphatase, bilirubin predict outcomes in primary biliary cirrhosis

Alkaline phosphatase, bilirubin predict outcomes in primary biliary cirrhosis

Levels of alkaline phosphatase that were two times the upper limit of normal at one year after study enrollment best predicted patient outcomes.

Heart not protected by vitamins

Heart not protected by vitamins

Multivitamins did not decrease the risk of developing cardiovascular disease in women.

HIV linked to hearing loss

HIV linked to hearing loss

HIV-positive patients demonstrated worse higher- and lower-frequency hearing, even after accounting for other factors.

Ebola epidemic may have been started by bat exposure

Ebola epidemic may have been started by bat exposure

Ebola epidemics are zoonotic in origin, spreading through contact with bats or larger wildlife.

Diabetes patients' unmet needs may impact disease control

Diabetes patients' unmet needs may impact disease control

More adverse outcomes were present in patients that reported having unmet material needs, such as food insecurity and cost.

Fast-acting Ebola test granted for emergency use by FDA

Fast-acting Ebola test granted for emergency use by FDA

The LightMix Ebola Zaire rRT-PCR Test offers results in three days, compared with other tests that can take up to a day to produce results.

Saxenda earns FDA approval for weight management

Saxenda earns FDA approval for weight management

The FDA has approved Saxenda (liraglutide [rDNA origin]) injection for chronic weight management.

Physical activity may detect cardiometabolic risk

Physical activity may detect cardiometabolic risk

Compared with consistently inactive patients, consistently active and irregularly active patients had lower fasting glucose, and had favorable random glucose and hemoglobin A1c.

Ambulatory BP monitors recommended by USPSTF

Ambulatory BP monitors recommended by USPSTF

Ambulatory blood pressure monitoring does a better job of predicting future events.

Recommendations for improving access to contraception issued

Recommendations for improving access to contraception issued

Barriers include knowledge deficits, cost and insurance coverage, unnecessary medical testing.

New standards of care for diabetes released

New standards of care for diabetes released

Standards include new recommendations for statin treatment based on individual risk profile

FDA reconsidering ban on blood donations from men who have sex with men

FDA reconsidering ban on blood donations from men who have sex with men

The FDA is releasing draft guidance that would allow blood donations from men who have sex with men.

Heart failure survival rates higher in obese, overweight patients

Heart failure survival rates higher in obese, overweight patients

The researchers found that 38% of obese and 45% of overweight patients died over 10 years, compared with 51% of normal-weight patients.

New drug combo wins FDA approval to treat UTIs, intra-abdominal infections

New drug combo wins FDA approval to treat UTIs, intra-abdominal infections

Ceftolozane/tazobactam is the fourth antibiotic to be FDA approved in 2014

Psoriasis linked to increased chronic kidney disease, glomerulonephritis risk

Psoriasis linked to increased chronic kidney disease, glomerulonephritis risk

The increased risk of CKD and GN was seen in patients with both mild and severe psoriasis.

SLIT-tablet seems safe for patients with asthma, allergic rhinitis

SLIT-tablet seems safe for patients with asthma, allergic rhinitis

No serious local allergic swellings or serious allergic reactions among SLIT-tablet-treated individuals with asthma.

Peramivir earns FDA approval to ease flu symptoms in adults

Peramivir earns FDA approval to ease flu symptoms in adults

Patients given paramivir had flu symptoms ease 21 hours sooner compared with patients left untreated.

Thiazide diuretic prophylaxis not linked to increased diabetes risk

Thiazide diuretic prophylaxis not linked to increased diabetes risk

For patients receiving and not receiving thiazide diuretics, the incidence level of DM at 10 years after first stone event was 9.2% and 4.2%, respectively.

Low glycemic index DASH-style diet may not improve cardiovascular benefits

Low glycemic index DASH-style diet may not improve cardiovascular benefits

Insulin sensitivity, lipid levels, and systolic blood pressure were not improved among patients assigned a DASH-style or low-glycemic diet.

Viekira Pak HCV combo tx gets FDA nod

Viekira Pak HCV combo tx gets FDA nod

The novel combination treatment is indicated for patients with chronic hepatitis C virus (HCV) genotype 1 infection, including cirrhosis.

High-dose flu vaccine better for seniors in nursing homes

High-dose flu vaccine better for seniors in nursing homes

Stronger improvement in the immune response was seen in frail senior patients living in nursing homes who received a high-dose flu vaccine.

Metformin may promote weight loss in obese kids

Metformin may promote weight loss in obese kids

Metformin treatment correlated with significant reduction in energy intake.

Geospatial map provides insight into HIV/hepatitis C mortality rates

Geospatial map provides insight into HIV/hepatitis C mortality rates

Multiple cause methodologies were used to illustrate HIV/AIDS and hepatitis C infection rates in Massachusetts.