Web Exclusives

Comparing anticoagulants to prevent venous thromboembolism after hip and knee arthroplasty

Comparing anticoagulants to prevent venous thromboembolism after hip and knee arthroplasty

Fondaparinux and rivaroxaban were associated with increased risk of major bleeding in patients who underwent total hip or knee arthroplasty.

Lifestyle intervention provides minimal benefit in improving glycemic control in type 2 diabetes

Lifestyle intervention provides minimal benefit in improving glycemic control in type 2 diabetes

Lifestyle interventions maintain glycemic control in patients with type 2 diabetes.

Antiemetics: a clinical practice guideline update from ASCO

Antiemetics: a clinical practice guideline update from ASCO

The updated guidelines will help clinicians prevent and manage nausea and vomiting caused by antineoplastic agents or radiation therapy in cancer patients.

Forty percent of hospitalized patients report breakdowns in care

Forty percent of hospitalized patients report breakdowns in care

Hospital patients reported breakdowns in care, which included information exchange, medications, delays in admission, team communication, providers' manner, and discharge.

Colorectal cancer mortality rates increasing in younger white adults

Colorectal cancer mortality rates increasing in younger white adults

Researchers analyzed colorectal cancer mortality rates among individuals between 20 and 54 years of age from 1970 through 2014.

Adding oats to a gluten-free diet may not affect patients with celiac disease

Adding oats to a gluten-free diet may not affect patients with celiac disease

The addition of oats to a gluten-free diet did not affect symptoms, histology, immunity, or serologic features in patients with celiac disease.

Tips for avoiding pneumonia in patients with COPD

Tips for avoiding pneumonia in patients with COPD

The COPD Foundation has released tips for patients with COPD to avoid pneumonia and exacerbations.

CTE found in high proportion of deceased football players

CTE found in high proportion of deceased football players

A new study finds compelling evidence of a strong link between chronic traumatic encephalopathy and North American football.

Occupational pesticide exposure linked to fixed airflow obstruction and chronic bronchitis

Occupational pesticide exposure linked to fixed airflow obstruction and chronic bronchitis

Results show that exposure to pesticides and herbicides is associated with fixed airflow obstruction and chronic bronchitis.

Sexually risky behavior more common in women with mental disorders than in men

Sexually risky behavior more common in women with mental disorders than in men

Women with mental illness engage in significantly more sexually risky behaviors than men, and personality risk scores are a significant predictor of total sex acts for women but not men.

Treating acute COPD exacerbations with prednisone and doxycycline

Treating acute COPD exacerbations with prednisone and doxycycline

Researchers found that doxycycline plus prednisone did not prolong the time between exacerbations in patients with COPD.

Sugar consumption linked to increased risk of mood disorders

Sugar consumption linked to increased risk of mood disorders

Research reveals an adverse effect of sugar intake from sweet foods and beverages on long-term psychological health.

Offering rapid HIV testing to patients increases overall testing rate in the emergency department

Offering rapid HIV testing to patients increases overall testing rate in the emergency department

Rapid HIV testing offered in parallel to patient-clinician consultations increases the testing rate in the emergency department.

Transcranial magnetic stimulation outcomes similar in younger and older adults with depression

Transcranial magnetic stimulation outcomes similar in younger and older adults with depression

Researchers found no difference in outcomes between older and younger adults undergoing transcranial magnetic stimulation for depression.

Human embryo editing repairs genetic mutation that causes hypertrophic cardiomyopathy

Human embryo editing repairs genetic mutation that causes hypertrophic cardiomyopathy

The gene-editing tool called CRISPR-Cas9 could have the potential to treat and prevent other genetic diseases.

Regular alcohol consumption associated with lower risk of diabetes

Regular alcohol consumption associated with lower risk of diabetes

Consumption of alcohol 3 to 4 days weekly is associated with a significantly lower risk for diabetes in men and women.

WHO releases new guidelines in response to pretreatment HIV drug resistance

WHO releases new guidelines in response to pretreatment HIV drug resistance

The new guidelines address the issue of how to manage pretreatment HIV drug resistance in countries where the prevalence of is 10% or higher.

Long-term response to mood stabilizers in patients with bipolar disorder

Long-term response to mood stabilizers in patients with bipolar disorder

Mixed and psychotic features and comorbid anxiety disorder were also associated with poor treatment response.

CVD prevention: New USPSTF guidelines for lifestyle counseling

CVD prevention: New USPSTF guidelines for lifestyle counseling

The USPSTF updated their 2012 recommendations on behavior lifestyle counseling for preventing cardiovascular disease.

Child with HIV suppresses virus without antiretroviral therapy for more than 8 years

Child with HIV suppresses virus without antiretroviral therapy for more than 8 years

A child who was diagnosed with HIV at 1 month and received early treatment has suppressed the virus without anti-HIV therapy for 8.5 years.

Poor metabolic health associated with depression regardless of body mass index

Poor metabolic health associated with depression regardless of body mass index

Researchers found an association between poor metabolic health and depression, regardless of weight status.

Completing the antibiotic course: Is it necessary?

Completing the antibiotic course: Is it necessary?

Completing the antibiotic course increases the chance of patients developing antibiotic resistance, according to the authors.

Alcohol screening and brief intervention: A practice manual for clinicians

Alcohol screening and brief intervention: A practice manual for clinicians

The AAFP has created an alcohol screening practice manual to help family physicians prevent alcohol misuse.

Contraception and adolescents: ACOG releases counseling recommendations for clinicians

Contraception and adolescents: ACOG releases counseling recommendations for clinicians

The ACOG released recommendations to help clinicians counsel adolescents about using contraception.

Dalazatide effective for skin lesions in plaque psoriasis

Dalazatide effective for skin lesions in plaque psoriasis

Dalazatide treatment reduced the plasma levels of multiple inflammation markers and reduced the expression of T cell activation markers on peripheral blood memory T cells.

Screening guidelines for pediatric psoriasis comorbidities

Screening guidelines for pediatric psoriasis comorbidities

The guidelines are the first to provide recommendations for comorbidity screening in pediatric psoriasis patients.

12.9 million infants worldwide not vaccinated in 2016: A WHO report

12.9 million infants worldwide not vaccinated in 2016: A WHO report

Nearly 1 in 10 infants did not receive any vaccinations in 2016, according to the World Health Organization.

CDC urges measles vaccine for European travelers

CDC urges measles vaccine for European travelers

Most measles cases in the United States are the result of international travel.

VZV-related community-acquired pneumonia linked to morbidity, mortality

VZV-related community-acquired pneumonia linked to morbidity, mortality

The hospital and ICU mortality rates of critically ill patients with VZV-CAP were 24% and 17%, respectively.

Bee stings and allergies: prevention and treatment tips

Bee stings and allergies: prevention and treatment tips

Symptoms of an allergic reaction to an insect sting may include itching and hives, swelling in the throat or tongue, difficulty breathing, dizziness, stomach cramps, nausea, or diarrhea.

Clinician communication affects parental decision-making with pediatric influenza vaccine

Clinician communication affects parental decision-making with pediatric influenza vaccine

About half of patients accepted influenza vaccination for their child if the clinician used a presumptive vs participatory initiation format.

Ovarian cancer screening: a USPSTF recommendation statement

Ovarian cancer screening: a USPSTF recommendation statement

The USPSTF states that the harms of screening for ovarian cancer in asymptomatic women outweigh the benefits.

Algal blooms pose summertime health risk

Algal blooms pose summertime health risk

Algal blooms produce toxins that can cause illness in people and animals and can block sunlight or use up oxygen in water, which can kill fish and plants.

Telbivudine prevents hepatitis B transmission during early pregnancy

Telbivudine prevents hepatitis B transmission during early pregnancy

Telbivudine administered during early and middle pregnancy prevented hepatitis B transmission from mother to infants in all participants receiving antiviral treatment.

Sleep disorders may increase risk for Alzheimer's disease

Sleep disorders may increase risk for Alzheimer's disease

Obstructive sleep apnea and sleep-disordered breathing are associated with amyloid deposition.

Blood-borne viruses more common in patients with severe mental illness

Blood-borne viruses more common in patients with severe mental illness

HIV, hepatitis B, and hepatitis C infections are more common among individuals with severe mental illness.

Benefits of lithium vs quetiapine in patients with early manic bipolar episodes

Benefits of lithium vs quetiapine in patients with early manic bipolar episodes

Individuals with a first manic episode with psychotic features were randomly assigned to receive lithium or quetiapine monotherapy during the randomized controlled trial.

Moderate weight gain in early to middle adulthood linked to increased risk of chronic diseases

Moderate weight gain in early to middle adulthood linked to increased risk of chronic diseases

Adulthood weight gain is associated with an increased risk of major chronic diseases and mortality.

WHO updates Essential Medicines List, recommendations for antibiotics

WHO updates Essential Medicines List, recommendations for antibiotics

The update includes 30 new medicines for adults and 25 for children and groups antibiotics into 3 distinct categories.

Effects of the obesity paradox: VTE risk in atrial fibrillation

Effects of the obesity paradox: VTE risk in atrial fibrillation

Researchers found a paradoxical increase in thromboembolism risk in low-weight patients with atrial fibrillation and VTE who were treated with direct oral anticoagulants.

Type 2 diabetes patients benefit from depression screening

Type 2 diabetes patients benefit from depression screening

The annual screening could decrease negative health outcomes and may be a cost-effective way to reduce complications.

Adverse events common in hospitalized patients taking antibiotics

Adverse events common in hospitalized patients taking antibiotics

Many adverse events could be avoidable with more judicious use of antibiotics.

NASEM report outlines strategy to combat opioid epidemic

NASEM report outlines strategy to combat opioid epidemic

The FDA commissioned the report to provide an update on current evidence on research, care, and education in the pain field, and to identify actionable measures for the FDA to more adequately address the ongoing opioid epidemic.

Higher childhood intelligence linked to lower mortality risk

Higher childhood intelligence linked to lower mortality risk

Researchers sought to examine the link between intelligence scores during childhood and leading causes of death during the life course.

Early antiretroviral therapy initiation linked to bone loss in HIV patients

Early antiretroviral therapy initiation linked to bone loss in HIV patients

Early antiretroviral therapy initiation may increase the rate of bone loss in HIV patients.

Walgreens expands availability of PrEP for HIV prevention

Walgreens expands availability of PrEP for HIV prevention

Providers in 17 new Walgreens locations will be able to prescribe PrEP for HIV prevention.

Social support boosts rehabilitation in adult COPD patients

Social support boosts rehabilitation in adult COPD patients

Patients are more likely to exercise and participate in pulmonary rehabilitation if they live with others and have a caregiver.

Coffee consumption associated with lower mortality risk

Coffee consumption associated with lower mortality risk

Coffee consumption is associated with a lower risk of all-cause mortality for men and women, specifically in African Americans, Japanese Americans, Latinos, and whites.

FDA approves first generic version of Truvada for HIV

FDA approves first generic version of Truvada for HIV

The drug is indicated for use in combination with other antiretroviral agents for the treatment of pediatric and adult patients with HIV-1.

Cardiovascular and cerebrovascular risk may decrease with LABA/LAMA in COPD

Cardiovascular and cerebrovascular risk may decrease with LABA/LAMA in COPD

LABA/LAMA is associated with a similar or lower risk of cardiovascular and cerebrovascular adverse events compared to treatment with LABA/inhaled corticosteroid.

Antibody screenings could detect celiac disease in asymptomatic children

Antibody screenings could detect celiac disease in asymptomatic children

Serum TG2A screening has a positive predictive value of 61% to detect celiac disease.

Opioid use increases risk of cardiac events in older COPD patients

Opioid use increases risk of cardiac events in older COPD patients

Users of opioid-only agents had significantly increased rates of emergency room visits and hospitalizations for ischemic heart disease and IHD-related mortality.

Increased adenoma detection rate associated with lower risk of colorectal cancer and death

Increased adenoma detection rate associated with lower risk of colorectal cancer and death

An increased ADR is associated with an adjusted hazard ratio of 0.63 for interval colorectal cancer and 0.50 for cancer death.

Beta-blocker therapy may reduce exacerbations in moderate-to-severe COPD

Beta-blocker therapy may reduce exacerbations in moderate-to-severe COPD

Cardiac geometry demonstrated by non-contrast computerized tomography scan can predict which patients will respond to β-blocker therapy with a reduction in exacerbation frequency.

CDC: Opioid prescription rate remains high, inconsistent in the United States

CDC: Opioid prescription rate remains high, inconsistent in the United States

However, the number of opioids prescribed decreased between 2010 and 2015.

Cardiometabolic comorbidity rates high in psoriasis patients

Cardiometabolic comorbidity rates high in psoriasis patients

The most common comorbidities found in patients with psoriasis are hyperlipidemia, hypertension, depression, type 2 diabetes mellitus, and obesity.

Biologic treatment for psoriasis shows long-term effectiveness

Biologic treatment for psoriasis shows long-term effectiveness

Researchers sought to analyze long-term and real-world outcome data in patients with moderate-to-severe psoriasis after starting biologic treatment.

Aspirin effective in preventing preterm preeclampsia in women at high risk

Aspirin effective in preventing preterm preeclampsia in women at high risk

Preterm preeclampsia occurred in 13 participants (1.6%) in the aspirin group, as compared with 35 (4.3%) in the placebo group.

Majority of opioid prescriptions are written for patients with mental disorders

Majority of opioid prescriptions are written for patients with mental disorders

Among the nearly 40 million Americans who have a mental health condition, about 19% use prescription opioids.

Antibiotics improve short-term outcomes in small skin abscesses

Antibiotics improve short-term outcomes in small skin abscesses

Antibiotics in conjunction with incision and drainage improved short-term outcomes compared with incision and drainage alone.

Proton pump inhibitor use associated with excess risk of death

Proton pump inhibitor use associated with excess risk of death

Risk of death is increased among those without gastrointestinal conditions and with prolonged use.

Women with bipolar disorder have high rate of sexual distress

Women with bipolar disorder have high rate of sexual distress

Overall, 54% of women with bipolar disorder reported sexual distress and 39% were not satisfied with their sexual life.

Risk-scoring model predicts advanced colorectal neoplasia in younger adults

Risk-scoring model predicts advanced colorectal neoplasia in younger adults

The score could help predict advanced colorectal neoplasia in adults younger than 50 years of age.

Thyroid disease associated with higher incidence of manic relapse in bipolar disorder

Thyroid disease associated with higher incidence of manic relapse in bipolar disorder

Thyroid disease may be a risk factor for manic relapse in patients with bipolar disorder.

Frequent coffee and herbal tea consumption linked to lower liver stiffness

Frequent coffee and herbal tea consumption linked to lower liver stiffness

The Rotterdam Study found that frequent coffee and herbal tea consumption is associated with lower liver stiffness in the general population.

Chlorhexidine oral rinse solution ineffective for aspiration pneumonia

Chlorhexidine oral rinse solution ineffective for aspiration pneumonia

Study findings suggest that nursing home residents should receive more guidance in using strategies to prevent aspiration during eating and drinking.

CDC: 101 influenza deaths in children reported for 2016-17

CDC: 101 influenza deaths in children reported for 2016-17

A total of 101 influenza-related deaths occurred among children throughout the 2016-17 flu season.

Hepatitis B vaccine reduces risk of non-Hodgkin lymphoma in adolescents

Hepatitis B vaccine reduces risk of non-Hodgkin lymphoma in adolescents

The universal vaccination against hepatitis B virus infection prevented non-Hodgkin lymphoma in adolescents.

Maternal antibodies inhibit antigenic responses to vaccines in infants

Maternal antibodies inhibit antigenic responses to vaccines in infants

Vaccines given shortly after birth demonstrated a strong inhibitory response to maternal antibodies.

High-dose vitamin D supplement use increasing, poses risk of adverse effects

High-dose vitamin D supplement use increasing, poses risk of adverse effects

Although research has emphasized the possible benefits of vitamin D, high dosages pose potential risks.

USPSTF recommends obesity screening in children aged 6 years and older

USPSTF recommends obesity screening in children aged 6 years and older

The USPSTF has released updated recommendations on obesity screening in children and adolescents to focus on intensive behavioral interventions.

Updated meningococcal vaccine guidelines reflect more dosing options

Updated meningococcal vaccine guidelines reflect more dosing options

The Advisory Committee on Immunization Practices released updated guidelines to include recommendations for the 3-dose formulation of serogroup B meningococcal vaccine.

Physical activity may not reduce the risk of dementia

Physical activity may not reduce the risk of dementia

Results from a 27-year follow-up study found no association between physical activity and a lower risk of dementia.

Breast, ovarian cancer risks estimated for BRCA1/BRCA2 mutation carriers

Breast, ovarian cancer risks estimated for BRCA1/BRCA2 mutation carriers

Breast cancer risk is increased with a larger number of first- and second-degree relatives diagnosed as having breast cancer for both BRCA1/BRCA2 carriers.

Amphotericin B superior to itraconazole for HIV-associated talaromycosis

Amphotericin B superior to itraconazole for HIV-associated talaromycosis

Treatment with amphotericin B was superior to itraconazole as an induction therapy for HIV-associated talaromycosis.

Risperidone treatment may delay relapse episodes in bipolar disorder

Risperidone treatment may delay relapse episodes in bipolar disorder

Researchers found that mood relapse episodes were delayed with risperidone long-acting injection.

Managing comorbidities linked to childhood obesity

Managing comorbidities linked to childhood obesity

A point-of-care resource tool may help clinicians better manage childhood overweight- and obesity-related comorbidities.

Women veterans lack access to effective health care in civilian practice

Women veterans lack access to effective health care in civilian practice

Civilian healthcare providers need to be educated on the importance of screening women for military service and also be aware of the unique healthcare needs of this population.

Advanced practice preceptor development program improves student transitions into practice

Advanced practice preceptor development program improves student transitions into practice

An innovative advanced practice preceptor program can help students and novices transition into established professionals.

NPs improve care coordination for high-risk complex care patients post-discharge

NPs improve care coordination for high-risk complex care patients post-discharge

Post-discharge care from hospital to community coordinated by an NP in high-risk complex care patients reduced hospital readmission rates.

Managing patients with chronic heart failure

Managing patients with chronic heart failure

Clinicians will encounter more patients at risk for CHF as the population ages and cardiovascular risk factors become more prevalent.

NPs have favorable view of retail health clinics

NPs have favorable view of retail health clinics

A survey found that 77.4% of NPs reported that the care provided in retail health clinics was in accordance with evidence-based guidelines.

Rivaroxaban decreased VTE rate in high-risk orthopedic joint surgery patients

Rivaroxaban decreased VTE rate in high-risk orthopedic joint surgery patients

Researchers developed a protocol to demonstrate the efficacy of rivaroxaban in lowering the risk of venous thromboembolism among orthopedic joint surgery patients.

Mammogram referral, screening rates boosted with point-of-care screening program

Mammogram referral, screening rates boosted with point-of-care screening program

A breast cancer screening program helped improve mammography referral and screening rates in a federally qualified health center.

Preventing holiday weight gain among rural hospital nightshift employees

Preventing holiday weight gain among rural hospital nightshift employees

Using collaboration and technology, NPs can help patients prevent weight gain and obesity-related diseases.

AANP 2017: More NPs choosing primary care

AANP 2017: More NPs choosing primary care

Nearly 90% of nurse practitioners are prepared in primary care programs in 2017.

AANP 2017: Teaching strategies to enhance intergenerational learning

AANP 2017: Teaching strategies to enhance intergenerational learning

Understanding the different attitudes and skills that different generations and professions bring to relationships can increase working confidence and self-efficacy.

AANP 2017: NPs better able to diagnose and treat mental health disorders with greater exposure as students

AANP 2017: NPs better able to diagnose and treat mental health disorders with greater exposure as students

Diagnostic and treatment competency levels in mental health disorders improved with increased educational time on these conditions.

Postpartum antiretroviral therapy is beneficial in HIV-positive women

Postpartum antiretroviral therapy is beneficial in HIV-positive women

Continued antiretroviral therapy was found to be safe and beneficial in HIV-positive postpartum women with high CD4+ T cell counts.

AANP 2017: Revolutionizing health care

AANP 2017: Revolutionizing health care

The AANP 2017 National Conference will be held from June 20 through June 25 in Philadelphia.

Use of ketamine for pain management and treatment of depression

Use of ketamine for pain management and treatment of depression

Ketamine may alleviate depression, pain, and adverse effects associated with opioid treatment.

DASH diet associated with lower risk of gout

DASH diet associated with lower risk of gout

The DASH diet could offer a dietary strategy that may help prevent gout and its comorbidities in high-risk patients with hyperuricemia.

A link between antiretroviral therapy and diabetes in HIV patients?

A link between antiretroviral therapy and diabetes in HIV patients?

HIV-infected patients on ART had approximately 4 and 1.5 greater odds of developing diabetes mellitus and metabolic syndrome, respectively.

Degludec vs glargine in type 2 diabetes for cardiovascular events

Degludec vs glargine in type 2 diabetes for cardiovascular events

Degludec is noninferior to glargine regarding the incidence of major cardiovascular events among patients with type 2 diabetes.

Quality of life in military HIV patients affected by advanced disease and mental comorbidity

Quality of life in military HIV patients affected by advanced disease and mental comorbidity

Factors linked to health-related quality of life in military HIV patients include advanced HIV disease and mental or medical comorbidity.

Majority of birth defects have unknown etiology

Majority of birth defects have unknown etiology

About 80% of birth defects between 2005 and 2009 have an unknown etiology.

Increased coffee consumption may reduce risk of hepatocellular carcinoma

Increased coffee consumption may reduce risk of hepatocellular carcinoma

Researchers conducted a meta-analysis to determine the association between coffee consumption and risk of hepatocellular carcinoma.

Too much or too little gestational weight gain increases risk of adverse outcomes

Too much or too little gestational weight gain increases risk of adverse outcomes

Gestational weight gain greater than or less than guideline recommendations is associated with an increased risk of adverse outcomes.

Tenofovir prevents prenatal transmission of HBV in pregnancy

Tenofovir prevents prenatal transmission of HBV in pregnancy

Pregnant women with a high hepatitis B viral load who receive tenofovir have a reduced risk for passing the virus to their child.

Endoscopy's role in primary sclerosing cholangitis: a clinical guideline

Endoscopy's role in primary sclerosing cholangitis: a clinical guideline

The guideline is intended to be an educational device to provide information that may assist endoscopists in providing care to patients.

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