Patients with chronic HCV infection who have achieved a sustained virologic response with treatment may still be at risk for complications such as hepatocellular carcinoma.
Women who took probiotics in their second trimester had lower rates of gestational diabetes.
Patients with septic shock taking phenylephrine during the 2011 norepinephrine shortage experienced higher in-hospital mortality rates.
Short-term oral corticosteroid use associated with increased risk for sepsis, venous thromboembolism
Approximately 1 in 5 American adults use corticosteroids in the short term, which is associated with an increased risk for sepsis, venous thromboembolism, and fracture.
Road closures may create delays in emergency care for nonparticipants with acute medical conditions who live close to marathon routes.
The guideline highlights the incidence, risk factors, and preventive approaches of SUDEP.
Researchers conducted a randomized controlled trial to determine whether inpatient rehabilitation provided greater improvements compared with a monitored home-based program alone.
The guideline will help clinicians determine the appropriate treatment of patients with metastatic pancreatic cancer.
Patients with greater clinical symptom severity had lower quality of life and higher functional impairment.
Reviews containing "wishlists" indicate that consumer needs are not adequately addressed by the apps that are currently available.
Aggressive testing, diagnosis, treatment, and prevention methods, such as needle exchange for those who inject drugs, are some of the options that the NASEM explored to target hepatitis elimination.
Intradetrusor injection of onabotulinumtoxin A impairs afferent and efferent nerves, but an injection-free drug delivery approach only impairs the bladder afferent nerves.
Most patients in primary care with undiagnosed chest pain do not undergo diagnostic testing.
Use of the empowerment approach is necessary for health promotion in older patients with COPD, but little attention has been paid to the dimensions of empowerment in COPD management.
The findings show no significant difference among sertraline monotherapy, lithium monotherapy, or a combination of the 2 medications.
The USPSTF recommends that prostate cancer screenings should be an individual decision.
Utibron Neohaler inhalation powder is indicated for the long-term maintenance treatment of airflow obstruction in patients with COPD.
Harvoni and Sovaldi have been approved for pediatric patients with HCV genotypes.
Celiac disease is associated with anorexia nervosa before and after a diagnosis of celiac disease.
Serum concentration levels of several antidepressants were lower in cigarette smokers compared with nonsmokers.
The test will provide information on an individual's genetic predisposition to 10 diseases or conditions.
The European Respiratory Society and the American Thoracic Society have released a guideline for the treatment of patients with COPD exacerbations.
Vitamin D and calcium supplementation not effective for lowering cancer risk in postmenopausal women
Vitamin D and calcium did not result in a significantly lower risk of all-type cancer, including breast cancer, in postmenopausal women.
Data from the Osteoarthritis Initiative show that total knee replacement has minimal effects on quality of life among patients with knee osteoarthritis.
The researchers found heterogeneity in the association between recorded alcohol consumption and the initial presentation of 12 cardiovascular diseases.
The recently released CDC guidelines on opioid prescribing remain a topic of debate.
The American Academy of Otolaryngology—Head and Neck Surgery foundation has released an updated clinical guideline for benign paroxysmal positional vertigo.
Radiofrequency treatment is an effective option for treating refractory chronic knee, hip, and shoulder joint pain.
Patients with chronic pain who are hospitalized have a higher risk of morbidity and mortality, longer lengths of stay, and more frequent readmissions than patients without chronic pain.
Regimens for the treatment of hepatitis C that included ribavirin had more mild or moderate adverse events than those without.
The USPSTF evaluated the benefits and harms of screening vs not screening, targeted vs universal screening, and treatment for celiac disease.
A meta-analysis suggests that patients who take gastric acid suppressants may have a higher risk for recurrent CDI.
Drug-drug interactions are common in patients taking hepatitis C virus medications, and consulting with a pharmacist can be beneficial.
Patients taking linagliptin had decreased HbA1c as well as reactive oxygen species generation and plasma lipid peroxide levels.
Adolescents with type 2 diabetes decreased HbA1c levels after using insulin pump therapy for a 3-month period.
PCV10 decreases rate of pneumonia among vaccine-eligible children and older, unvaccinated children.
Elevated cardiac troponin T is also strongly prognostic of cardiac mortality observed in association with community-acquired pneumonia.
Factors that contribute to antibiotic choice for CAP include patient age, previous antibiotic receipt, and private insurance.
Researchers observed a higher incidence of hypertension in patients with knee osteoarthritis compared with patients without osteoarthritis.
Use of oral contraceptives did not increase the risk for cancer in women and decreased the risk for colorectal, endometrial, ovarian, and lymphatic and hematopoietic cancers.
The updated guideline includes recent advances in diagnostic imaging and improvements in catheter-based and surgical interventions for patients with valvular heart disease.
The Endocrine Society has released a clinical guideline for the diagnosis and treatment of functional hypothalamic amenorrhea.
Early, goal-directed therapy did not result in better outcomes for mortality for patients with septic shock.
A daily dose of atorvastatin could reduce pulmonary artery pressure among patients with COPD.
A novel technique involving NPPV reduced the risks of nosocomial infection, requirement for intubation, and hospital mortality in patients with COPD.
Diabetes incidence rates in the US and glucose intolerance worldwide increased per 1°C increase in temperature.
Six guidelines establish updated clinical practice recommendations for the evaluation, diagnosis, and treatment of obstructive sleep apnea in adults.
Anticoagulation with dabigatran was associated with fewer bleeding complications compared with warfarin among patients undergoing ablation for atrial fibrillation.
Early feeding, skin-to-skin contact improves hospital admission rates for infants at risk of hypoglycemia
A hypoglycemia bundle was created in order to reduce hospital admission rates for infants at risk of hypoglycemia.
A high BMI is associated with an increased risk for severe liver disease, and the risk is higher in those who also have type 2 diabetes mellitus.
The drug combination significantly contributes to the overall population risk of opioid overdose.
Octogenarians with colorectal cancer have several differences in clinical and tumor characteristics, compared with younger patients with the disease.
Budesonide oral suspension treatment improved symptomatic, endoscopic, and histologic parameters in eosinophilic esophagitis.
A longer period between P2Y12 inhibitor administration and primary percutaneous coronary intervention improves coronary reperfusion.
The FDA has received 120 reports of serious cases of pancreatitis or death after the approval of Viberzi in May 2015.
No difference was observed in risk of overall cancer in patients with bipolar disorder who use lithium, compared with the general population.
For many off-label indications, the prescribed drug is often not supported by strong evidence for the respective indication.
The Stepping Up model of care produced a clinically and significantly significant improvement in HbA1c among adults with type 2 diabetes managed in primary care.
Same-day discharge after percutaneous coronary intervention for non-ST-segment elevation acute coronary syndromes was not predictive of 30-day readmission, death, or bleeding.
The students improved their basic knowledge of HPV and understood the benefits of the HPV vaccine.
Using measurements of vaginal fetal fibronectin levels and cervical length did not indicate spontaneous preterm birth among first-time pregnant women.
Data presented at NAPNAP show that an early-onset sepsis calculator can decrease the number of infants who received a sepsis work-up and prophylactic antibiotics.
The ACGME announces that residency programs can increase shift hours for first-year residents from 16 to 24 hours.
A higher incidence of subdural hematomas is associated with the increased use of antithrombotic drugs, particularly vitamin k antagonists among older patients.
Implementation of the FODMAP diet is an effective strategy to manage symptoms of IBS, including bloating and abdominal pain.
Reducing postpartum depression involves universal screening and appropriate referral and treatment by clinicians.
Suboptimal intake of 10 specific dietary factors is associated with a substantial proportion of deaths due to heart disease, stroke, or type 2 diabetes.
Risk of serious infections is similar among pregnant women with systemic inflammatory conditions using steroids, non-biologics, and TNF inhibitors.
The USPSTF concludes that evidence is insufficient to assess the balance of benefits and harms of performing screening pelvic examinations in asymptomatic women for the early detection and treatment of a range of gynecologic conditions.
Point of care lung ultrasound is an accurate tool for the diagnosis of pneumonia, according to researchers.
ACOG recommends that carrier screening should be provided to all women who are pregnant but ideally should be provided to women as they are considering pregnancy.
The position statement by the ADA incorporates updates in treatment and screening for patients with diabetic retinopathy.
The American College of Gastroenterology has released recommendations of preferred approaches for diagnosing and evaluating patients with abnormal liver test results.
The guidelines outline the diagnosis of CF and clarify diagnostic criteria and terminology for other disorders associated with CFTR mutations.
Researchers report that women and men in the United States will have lower life expectancy gains, compared with those in other countries.
The American Academy of Sleep Medicine recommends that the new pharmacologic guidelines be used in conjunction with other AASM guidelines for insomnia.
Younger age, relapsing forms of MS, fewer prior immunotherapy treatments, and lower baseline EDSS score were factors associated with better outcomes for stem cell transplantation.
Patients receiving vitamin D for deficiency without bolus doses experienced the most benefit.
Among GERD patients, the mean annual ARI episode dropped from 4.39 during the year before PPI treatment to 3.89 after treatment with a PPI.
Findings from a US claims-based retrospective study call for more effective antimicrobial treatments for patients with community-acquired pneumonia.
Surgical intervention after 24.5 days of acute pancreatitis may be beneficial for reducing postoperative complications.
The Veterans Administration and Department of Defense issue a clinical practice guideline regarding opioid therapy for chronic pain in veterans.
Investigators have proposed an algorithm to facilitate the decision-making process of clinical care for patients with very early hepatocellular carcinoma.
The ACIP has released the 2017 recommended immunization schedule for adults.
MRI scans showed that the brain size of infants grew faster between 12 and 24 months, the same time that behavioral signs of autism appeared.
Rivaroxaban once daily and dabigatran twice daily showed evidence of lower thromboembolic rates.
HCV infection is associated with cancers such as bile duct and pancreatic cancers and diffuse large B-cell lymphoma.
The ACP has released 3 recommendations for the treatment of patients with acute, subacute, and chronic low back pain.
Girls whose mothers consumed high amounts of licorice during pregnancy have more advanced pubertal maturation at age 12 years.
Using transvaginal mesh and biological graft in prolapse surgery did not improve outcomes of effectiveness, quality of life, or adverse events.
The schedule includes new or revised recommendations for several vaccines for children and adolescents.
After 10 years of low-dose CT screening in patients, 1.5 lung cancers and 2.4 major cancers per 10,000 people screened were induced by radiation.
Women with a good recovery after stroke and a moderate level of optimism had a 0.40‐fold reduction in the odds of developing new-onset poststroke depression.
Atypical antipsychotic adjunctive therapy and mood stabilizers may be a more effective treatment than mood stabilizer monotherapy.
NSAID use during ARI was associated with a 3.4-fold increased risk of AMI compared with 2.7-fold increased risk without NSAID use.
Symptoms of Seoul virus infection typically begin within 1 to 2 weeks after contact with infectious material and include fever, headache, and back pain.
Researchers measured vital status records to ascertain death from 16 site-specific malignancies.
The ACOG releases an updated committee opinion suggesting that low-risk women can benefit from minimal intervention during labor and delivery.
The Seeker System is approved to screen for four rare lysosomal storage disorders in newborns.
More than 10,000 Medicare beneficiaries die each year within 7 days of being discharged from emergency departments.
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Clinical Advisor Articles
- Metastatic pancreatic cancer: a new clinical practice guideline
- Sleep paralysis: A world between wakefulness and sleep
- Psychiatric comorbid conditions may impact quality of life in bipolar disorder
- Practice guideline released for sudden unexpected death in epilepsy
- Inpatient rehabilitation may not improve mobility in total knee arthroplasty
- Magnesium for patients taking opioids for pain
- Benign paroxysmal positional vertigo: a clinical practice guideline
- Valvular heart disease: 2017 updated guideline from the AHA/ACC
- Metastatic pancreatic cancer: a new clinical practice guideline
- Rheumatoid arthritis: risk factors, clinical signs, and treatment
- Neutrophil-to-lymphocyte ratio may predict mortality in community-acquired pneumonia
- AGA Institute releases practice update for managing patients cured of HCV infection
- Probiotics may lower risk of gestational diabetes
- Case Study in Urgent Care: Head injury
- Norepinephrine shortage led to higher mortality in septic shock patients