Web Exclusives

2017 Adult immunization schedule released by the CDC

2017 Adult immunization schedule released by the CDC

The ACIP has released the 2017 recommended immunization schedule for adults.

MRI may detect autism before age 1

MRI may detect autism before age 1

MRI scans showed that the brain size of infants grew faster between 12 and 24 months, the same time that behavioral signs of autism appeared.

Apixaban linked to higher rates of stroke than warfarin in patients with atrial fibrillation

Apixaban linked to higher rates of stroke than warfarin in patients with atrial fibrillation

Rivaroxaban once daily and dabigatran twice daily showed evidence of lower thromboembolic rates.

Hepatitis C infection linked to nonhepatic cancers among elderly patients

Hepatitis C infection linked to nonhepatic cancers among elderly patients

HCV infection is associated with cancers such as bile duct and pancreatic cancers and diffuse large B-cell lymphoma.

Noninvasive treatment for low back pain: a new clinical guideline from ACP

Noninvasive treatment for low back pain: a new clinical guideline from ACP

The ACP has released 3 recommendations for the treatment of patients with acute, subacute, and chronic low back pain.

Licorice consumption during pregnancy may be harmful for offspring

Licorice consumption during pregnancy may be harmful for offspring

Girls whose mothers consumed high amounts of licorice during pregnancy have more advanced pubertal maturation at age 12 years.

Prolapse surgery outcomes not improved with transvaginal mesh or biological graft

Prolapse surgery outcomes not improved with transvaginal mesh or biological graft

Using transvaginal mesh and biological graft in prolapse surgery did not improve outcomes of effectiveness, quality of life, or adverse events.

2017 immunization schedule for children and adolescents released by CDC

2017 immunization schedule for children and adolescents released by CDC

The schedule includes new or revised recommendations for several vaccines for children and adolescents.

Radiation exposure and cancer risk from CT screening: a risk-benefit analysis

Radiation exposure and cancer risk from CT screening: a risk-benefit analysis

After 10 years of low-dose CT screening in patients, 1.5 lung cancers and 2.4 major cancers per 10,000 people screened were induced by radiation.

Prestroke psychosocial factors linked to poststroke depression risk in women

Prestroke psychosocial factors linked to poststroke depression risk in women

Women with a good recovery after stroke and a moderate level of optimism had a 0.40‐fold reduction in the odds of developing new-onset poststroke depression.

Atypical antipsychotic therapy with mood stabilizers effective after bipolar episode

Atypical antipsychotic therapy with mood stabilizers effective after bipolar episode

Atypical antipsychotic adjunctive therapy and mood stabilizers may be a more effective treatment than mood stabilizer monotherapy.

NSAID use for respiratory infection increases myocardial infarction risk

NSAID use for respiratory infection increases myocardial infarction risk

NSAID use during ARI was associated with a 3.4-fold increased risk of AMI compared with 2.7-fold increased risk without NSAID use.

CDC expands investigation into Seoul virus outbreak

CDC expands investigation into Seoul virus outbreak

Symptoms of Seoul virus infection typically begin within 1 to 2 weeks after contact with infectious material and include fever, headache, and back pain.

Anxiety and depression may have predictive role in cancer mortality

Anxiety and depression may have predictive role in cancer mortality

Researchers measured vital status records to ascertain death from 16 site-specific malignancies.

Intervention during labor and birth: new recommendations from ACOG

Intervention during labor and birth: new recommendations from ACOG

The ACOG releases an updated committee opinion suggesting that low-risk women can benefit from minimal intervention during labor and delivery.

FDA approves first newborn screening system for rare metabolic disorders

FDA approves first newborn screening system for rare metabolic disorders

The Seeker System is approved to screen for four rare lysosomal storage disorders in newborns.

Death rate high in elderly within 7 days of discharge from emergency department

Death rate high in elderly within 7 days of discharge from emergency department

More than 10,000 Medicare beneficiaries die each year within 7 days of being discharged from emergency departments.

Mortality rate lower in US patients treated by foreign-educated internists

Mortality rate lower in US patients treated by foreign-educated internists

Researchers observed a somewhat lower mortality among patients treated by international graduates.

Electronic cigarette use linked to higher CVD risk

Electronic cigarette use linked to higher CVD risk

Electronic cigarettes cause an imbalance of cardiac autonomic tone and increased oxidative stress, which may increase cardiovascular risk.

High-potency statins increase hospitalization for community-acquired pneumonia

High-potency statins increase hospitalization for community-acquired pneumonia

Higher-potency statins increased hospitalization for community-acquired pneumonia compared with lower-potency statins.

Recurrent pneumonia resulting from misdiagnosed endobronchial suture—a case synopsis

Recurrent pneumonia resulting from misdiagnosed endobronchial suture—a case synopsis

Endobronchial suture should be considered in patients with recurrent pneumonia that is unresponsive to medical therapy.

Pneumococcal vaccination reduces pneumonia risk in COPD patients

Pneumococcal vaccination reduces pneumonia risk in COPD patients

Polyvalent pneumococcal vaccines offered protection against community-acquired pneumonia in COPD patients.

Meal timing and frequency in CVD prevention: an AHA scientific statement

Meal timing and frequency in CVD prevention: an AHA scientific statement

The AHA found that irregular eating patterns are less ideal for maintaining body weight and cardiometabolic health.

Pneumonia vaccine may not be effective in rheumatoid arthritis patients

Pneumonia vaccine may not be effective in rheumatoid arthritis patients

The PPSV23 vaccine may not prevent pneumonia in patients with rheumatoid arthritis.

VA lung cancer screening program finds high rate of incidental findings, low cancer detection rate

VA lung cancer screening program finds high rate of incidental findings, low cancer detection rate

An estimated 900,000 veterans of a population of 6.7 million VHA patients met the criteria for LCS.

Diabetes without insulin may not increase thromboembolic risk in atrial fibrillation

Diabetes without insulin may not increase thromboembolic risk in atrial fibrillation

Diabetes without insulin did not appear to increase thromboembolic risk in patients with atrial fibrillation treated with anticoagulation.

Thyroid hormone treatment linked to reduced risk of pregnancy loss in subclinical hypothyroidism

Thyroid hormone treatment linked to reduced risk of pregnancy loss in subclinical hypothyroidism

Treatment is associated with decreased loss of pregnancy among women with subclinical hypothyroidism.

CDC tips for prediabetes prevention and treatment

CDC tips for prediabetes prevention and treatment

Prediabetes does not always show clear symptoms; however, it can lead to type 2 diabetes, heart disease, or stroke.

Sepsis and septic shock: new guidelines for clinical management

Sepsis and septic shock: new guidelines for clinical management

Updated international guidelines for managing sepsis and septic shock have been released by the Society of Critical Care Medicine and European Society of Intensive Care Medicine.

CDC: Two-thirds of US youth consume at least one sugar-sweetened beverage per day

CDC: Two-thirds of US youth consume at least one sugar-sweetened beverage per day

Overall, US youth consumed an average 143 kcal from sugar-sweetened beverages, with boys consuming a higher percentage of calories than girls.

Accuracy of prediabetes screening tests is low

Accuracy of prediabetes screening tests is low

Fasting glucose is specific but not sensitive, and HbA1c is neither sensitive nor specific.

Earwax: a clinical practice guideline for management and treatment

Earwax: a clinical practice guideline for management and treatment

The guideline aims to help clinicians identify patients with cerumen impaction who may benefit from intervention.

USPSTF: Evidence lacking for obstructive sleep apnea screening

USPSTF: Evidence lacking for obstructive sleep apnea screening

The USPSTF found that there is uncertainty about the accuracy of screening tools for obstructive sleep apnea in adults.

Efficacy of renin angiotensin system inhibitors for coronary artery disease

Efficacy of renin angiotensin system inhibitors for coronary artery disease

RASIs reduced cardiovascular events and death only when compared with placebo but not when compared with active controls.

One-third of asthma patients may be misdiagnosed

One-third of asthma patients may be misdiagnosed

About one-third of adults with physician-diagnosed asthma in the last 5 years may not have a current diagnosis.

FDA approves Trulance for chronic idiopathic constipation treatment

FDA approves Trulance for chronic idiopathic constipation treatment

Trulance has been approved for the treatment of chronic idiopathic constipation in adults.

Safety alert issued for LIFEPAK 1000 defibrillator

Safety alert issued for LIFEPAK 1000 defibrillator

The device has shut down due to an intermittent connection between the battery and electrical contacts.

FDA and EPA release final recommendations for fish consumption in pregnant women

FDA and EPA release final recommendations for fish consumption in pregnant women

For adults, the recommended serving size of fish is 4 ounces, while servings for children should be smaller based on their age and calorie intake.

LASIK surgery: a mixed bag of results?

LASIK surgery: a mixed bag of results?

Data from the PROWL studies show that most patients are satisfied with LASIK surgery, although many patients experience new symptoms.

Hypertension treatment in older adults: a new clinical practice guideline

Hypertension treatment in older adults: a new clinical practice guideline

The ACP and the AAFP has released a joint recommendation for the pharmacologic treatment of hypertension in adults aged 60 years and older.

Migraine increases stroke risk in surgical patients

Migraine increases stroke risk in surgical patients

Surgical patients with a history of migraine have an increased risk of perioperative ischemic stroke and a higher 30-day hospital readmission rate.

Lithium side effects and management strategies

Lithium side effects and management strategies

The declining rates for lithium use are linked to the burden of side effects and toxicity associated with the drug.

"Weekend warrior" activity reduces all-cause mortality risk

"Weekend warrior" activity reduces all-cause mortality risk

Individuals who perform their physical activity in 1 or 2 sessions during the week can still reduce their risk of mortality.

Depression literacy higher in women and linked to medication adherence

Depression literacy higher in women and linked to medication adherence

Some aspects of depression literacy were lower among patients with depression.

Monitoring asthma control in children: AAP recommendations for clinicians

Monitoring asthma control in children: AAP recommendations for clinicians

Recent advances in measuring asthma control tools have enhanced ongoing assessment and monitoring of asthma.

Drug and alcohol use associated with higher risk of adolescent firearm homicide

Drug and alcohol use associated with higher risk of adolescent firearm homicide

Substance use is associated with an increased risk of adolescent firearm homicide.

USPSTF recommends folic acid for all women who may become pregnant

USPSTF recommends folic acid for all women who may become pregnant

The USPSTF recommends folic acid supplement for all women who are capable of pregnancy or who are planning to become pregnant.

US spending on health care substantially increases, led by diabetes, ischemic heart disease

US spending on health care substantially increases, led by diabetes, ischemic heart disease

Spending on diabetes, IHD, and lower back and neck pain account for the highest amounts of spending by disease category.

NIH releases addendum guidelines to prevent peanut allergies through early introduction

NIH releases addendum guidelines to prevent peanut allergies through early introduction

The NIAID has issued addendum guidelines regarding the early introduction of peanut-containing foods to infants at risk for peanut allergies.

COPD exacerbations reduced with budesonide/formoterol treatment

COPD exacerbations reduced with budesonide/formoterol treatment

Budesonide/formoterol treatment decreased exacerbations in COPD after 3 months.

Patients with chronic diseases are frequently overly optimistic about life expectancy

Patients with chronic diseases are frequently overly optimistic about life expectancy

Self-estimated life expectancy rates may differ from clinician-estimated rates of survival.

Statin prescription rates lower among younger adults with severe dyslipidemia

Statin prescription rates lower among younger adults with severe dyslipidemia

Prescription rates for statins were dependent on age among patients with severe dyslipidemia.

Morning symptoms in COPD linked to limited physical activity

Morning symptoms in COPD linked to limited physical activity

Many patients with COPD report morning symptoms that are negatively associated with physical activity.

Fish oil, aspirin ineffective for reducing arteriovenous fistula failure

Fish oil, aspirin ineffective for reducing arteriovenous fistula failure

The study suggests that neither fish oil nor aspirin can be recommended for the prevention of AVF failure.

Psychiatric, behavioral conditions linked to future long-term opioid use

Psychiatric, behavioral conditions linked to future long-term opioid use

Patients diagnosed with a prior psychiatric condition have increased odds of long-term opioid receipt than patients without these conditions.

Updated guideline for oral pharmacologic treatment of type 2 diabetes

Updated guideline for oral pharmacologic treatment of type 2 diabetes

The ACP has updated the 2012 guideline to provide clinical recommendations of oral pharmacologic treatment of type 2 diabetes.

FDA approves first continuous glucose monitoring system to replace fingerstick test in diabetes

FDA approves first continuous glucose monitoring system to replace fingerstick test in diabetes

The FDA has approved a continuous glucose monitoring system to replace fingerstick blood sugar testing in patients with diabetes.

American Urological Association issues guideline for male urethral stricture

American Urological Association issues guideline for male urethral stricture

The guidelines provide a clinical framework for the diagnosis and treatment of male urethral stricture.

Mortality rates remain high among HIV-positive patients

Mortality rates remain high among HIV-positive patients

The HIV-positive population of the United Kingdom has a higher risk of death than the general population, despite availability of free treatment and care.

In-utero MRI more accurate than ultrasound for diagnosing fetal brain abnormalities

In-utero MRI more accurate than ultrasound for diagnosing fetal brain abnormalities

This finding suggests that any fetus with a suspected brain abnormality on ultrasound should have iuMRI to better inform counseling and management decisions.

"Zombie" outbreak in New York City caused by ultrapotent cannabinoid use

"Zombie" outbreak in New York City caused by ultrapotent cannabinoid use

The potency of synthetic cannabinoids is consistent with strong depressant effects that account for "zombie-like" behavior.

FDA bans powdered surgeon's and patient examination gloves

FDA bans powdered surgeon's and patient examination gloves

The FDA has issued a final ruling to ban powdered surgeon's gloves, powdered patient examination gloves, and absorbable powder for lubricating a surgeon's glove.

USPSTF recommends against routine serologic screening for genital herpes simplex virus

USPSTF recommends against routine serologic screening for genital herpes simplex virus

The USPSTF has released a final recommendation against routine serologic screening for genital herpes simplex virus infection.

Crizanlizumab reduces sickle cell-related pain

Crizanlizumab reduces sickle cell-related pain

Treatment with high-dose crizanlizumab resulted in an annual rate of sickle cell-related pain crises that was 45.3% lower compared with placebo.

Birth defect rate is 6% among US women with possible Zika virus infection

Birth defect rate is 6% among US women with possible Zika virus infection

Birth defects potentially related to Zika virus were identified in 6% of fetuses or infants of women included in the study.

Shared decision making boosts patients' knowledge of acute coronary syndrome risk

Shared decision making boosts patients' knowledge of acute coronary syndrome risk

The use of a decision aid in patients at risk of acute coronary syndrome increased patient knowledge about their risk.

FDA approves Eucrisa for eczema treatment

FDA approves Eucrisa for eczema treatment

In a controlled trial, participants receiving Eucrisa achieved clear or almost clear skin after 28 days of treatment.

FDA issues warning of anesthesia use in children and pregnant women

FDA issues warning of anesthesia use in children and pregnant women

The FDA warns against the repeated or prolonged use of anesthesia in pregnant women and in children younger than 3 years of age.

American Chronic Pain Association issues toolkit for clinicians

American Chronic Pain Association issues toolkit for clinicians

The toolkit will provide healthcare professionals with adequate tools to manage their patients' pain.

Restless legs syndrome: a new practice guideline

Restless legs syndrome: a new practice guideline

Evidence shows strong support for prescribing pramipexole, rotigotine, cabergoline, or gabapentin enacarbil to treat adults with restless legs syndrome symptoms.

Statins may reduce risk of Alzheimer's disease

Statins may reduce risk of Alzheimer's disease

Depending on race, sex, and ethnicity, the right statin type may lower the risk of Alzheimer disease.

CDC: Influenza vaccine rate low this season

CDC: Influenza vaccine rate low this season

Forty percent of people have reported receiving the flu vaccine thus far, including 37% of children.

VA grants veterans direct access to APRN care

VA grants veterans direct access to APRN care

The VA ruled to grant veterans direct access to advanced practice registered nurses who work in the VA healthcare system.

GOLD Report includes updated COPD management recommendations

GOLD Report includes updated COPD management recommendations

The GOLD Report includes a revised definition of COPD and updates guidelines for managing exacerbations.

Psilocybin treatment reduces depression, anxiety in cancer patients

Psilocybin treatment reduces depression, anxiety in cancer patients

Two studies found that psilocybin (magic mushrooms) treatment was effective for anxiety and depression.

Proposing new concepts and definitions in COPD

Proposing new concepts and definitions in COPD

It is important to use the right terminology when discussing medical terms, specifically ones associated with smoke-related respiratory conditions, according to the researchers.

Predicting COPD exacerbation onset with use of physiological parameters

Predicting COPD exacerbation onset with use of physiological parameters

Researchers conducted a systematic review of the effectiveness of monitoring physiological parameters to predict COPD exacerbations.

Integrating nurse practitioners into intensive care units

Integrating nurse practitioners into intensive care units

Ensuring successful integration of nurse practitioners into intensive care units includes orientation programs and leadership teams.

Many patients are not referred for penicillin allergy testing

Many patients are not referred for penicillin allergy testing

Most clinicians noted the need for allergy consultation but had never referred their patients to an allergist.

Report outlines strategy to improve food allergy safety in US

Report outlines strategy to improve food allergy safety in US

The Committee on Food Allergies concluded that the actual prevalence of food allergies is unknown due to misinterpretation of symptoms and lack of simple diagnostic tests.

Life expectancy in United States declined in 2015

Life expectancy in United States declined in 2015

From 2014 to 2015, the age-adjusted death rate for the total US population increased 1.2%.

ADA releases guidelines for psychosocial care for diabetes patients

ADA releases guidelines for psychosocial care for diabetes patients

The position statement provides recommendations for psychosocial assessment and care of individuals with diabetes.

VA offers hepatitis, HIV screening to veterans who received improper dental care

VA offers hepatitis, HIV screening to veterans who received improper dental care

A VA center in Wisconsin is advising veterans to be screened for hepatitis and HIV after receiving care from a dentist who did not follow VA procedures.

Novel method identifies patients with nonalcoholic fatty liver disease

Novel method identifies patients with nonalcoholic fatty liver disease

Researchers described a new method to quantify hepatic fibrogenesis flux rates in the liver tissue and noninvasively in blood.

Electroconvulsive therapy effective for major depressive disorder

Electroconvulsive therapy effective for major depressive disorder

Electroconvulsive therapy is effective for depression in patients with suicidal ideation and resistance to other treatments.

Outpatient program may be effective for pain self-management

Outpatient program may be effective for pain self-management

A program based on cognitive behavioral therapy and physical exercise could improve pain self-management in patients with complex pain.

FDA approves new drug for postmenopausal pain during sex

FDA approves new drug for postmenopausal pain during sex

Intrarosa provides an additional treatment option for women with dyspareunia caused by vulvar and vaginal atrophy.

Depression rate high in patients with mild cognitive impairment

Depression rate high in patients with mild cognitive impairment

About one-third of patients with MCI are also diagnosed with depression.

Testosterone treatment may increase risk of venous thromboembolism

Testosterone treatment may increase risk of venous thromboembolism

Researchers sought to determine the risk of venous thromboembolism associated with use of testosterone treatment.

New clinical trial underway to study efficacy of HIV vaccine

New clinical trial underway to study efficacy of HIV vaccine

The study will be the largest HIV vaccine clinical trial to take place in South Africa.

Smartphone questionnaire effective for monitoring mood instability

Smartphone questionnaire effective for monitoring mood instability

The Mood Zoom questionnaire rates anxiety, elation, sadness, anger, irritability, and energy on a 7-point scale.

AAP recommendations for behavioral and emotional problems in young children

AAP recommendations for behavioral and emotional problems in young children

Most young children with an emotional, behavioral, or relationship problem receive no interventions for their disorder.

Rates and causes of emergency department visits for adverse drug events

Rates and causes of emergency department visits for adverse drug events

Data regarding adverse drug events in the United States could help to focus medication safety initiatives in outpatient settings.

Elevated blood pressure trends have shifted worldwide

Elevated blood pressure trends have shifted worldwide

The prevalence of elevated blood pressure rates shifted from high-income to low- and middle-income countries.

Is vasectomy linked to risk of prostate cancer?

Is vasectomy linked to risk of prostate cancer?

Vasectomy can continue to be a safe method of contraception in men.

Alternative strategies effective for diagnosing gout

Alternative strategies effective for diagnosing gout

Multidimensional algorithms may help clinicians make a provisional diagnosis of gout.

Managing peripheral artery disease: an updated guideline

Managing peripheral artery disease: an updated guideline

The AHA/ACC guideline updates the 2005 recommendations on PAD management.

Calculator predicts success of live birth after in vitro fertilization

Calculator predicts success of live birth after in vitro fertilization

The findings may help couples plan infertility treatments more effectively.

Functional outcomes in septic arthritis after ultrasonography

Functional outcomes in septic arthritis after ultrasonography

Patients with septic arthritis with poor functional outcome who underwent ultrasonography showed decreased synovial thickness at 3 months.

Antenatal antiretroviral therapy reduces early HIV transmission

Antenatal antiretroviral therapy reduces early HIV transmission

Antenatal ART reduces rates of early HIV transmission but may increase risk of adverse maternal and neonatal outcomes.

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