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Obstructive sleep apnea in adults: a new clinical practice guideline

Obstructive sleep apnea in adults: a new clinical practice guideline

Six guidelines establish updated clinical practice recommendations for the evaluation, diagnosis, and treatment of obstructive sleep apnea in adults.

Dabigatran linked to fewer bleeding complications in patients with atrial fibrillation

Dabigatran linked to fewer bleeding complications in patients with atrial fibrillation

Anticoagulation with dabigatran was associated with fewer bleeding complications compared with warfarin among patients undergoing ablation for atrial fibrillation.

Early feeding, skin-to-skin contact improves hospital admission rates for infants at risk of hypoglycemia

Early feeding, skin-to-skin contact improves hospital admission rates for infants at risk of hypoglycemia

A hypoglycemia bundle was created in order to reduce hospital admission rates for infants at risk of hypoglycemia.

High BMI in late adolescence associated with increased risk of severe liver disease in men

High BMI in late adolescence associated with increased risk of severe liver disease in men

A high BMI is associated with an increased risk for severe liver disease, and the risk is higher in those who also have type 2 diabetes mellitus.

Opioid and benzodiazepine combination use significantly increases overdose risk

Opioid and benzodiazepine combination use significantly increases overdose risk

The drug combination significantly contributes to the overall population risk of opioid overdose.

Colorectal cancer characteristics different, outcomes worse among octogenarians

Colorectal cancer characteristics different, outcomes worse among octogenarians

Octogenarians with colorectal cancer have several differences in clinical and tumor characteristics, compared with younger patients with the disease.

Budesonide oral suspension may be effective for eosinophilic esophagitis

Budesonide oral suspension may be effective for eosinophilic esophagitis

Budesonide oral suspension treatment improved symptomatic, endoscopic, and histologic parameters in eosinophilic esophagitis.

Coronary reperfusion improved with longer time between antiplatelet therapy and PCI

Coronary reperfusion improved with longer time between antiplatelet therapy and PCI

A longer period between P2Y12 inhibitor administration and primary percutaneous coronary intervention improves coronary reperfusion.

Irritable bowel syndrome medication linked to pancreatitis in certain patients

Irritable bowel syndrome medication linked to pancreatitis in certain patients

The FDA has received 120 reports of serious cases of pancreatitis or death after the approval of Viberzi in May 2015.

Lithium not linked to increased cancer risk in patients with bipolar disorder

Lithium not linked to increased cancer risk in patients with bipolar disorder

No difference was observed in risk of overall cancer in patients with bipolar disorder who use lithium, compared with the general population.

Off-label antidepressant prescriptions not supported by strong scientific evidence

Off-label antidepressant prescriptions not supported by strong scientific evidence

For many off-label indications, the prescribed drug is often not supported by strong evidence for the respective indication.

Insulin initiation in primary care improves HbA1c levels

Insulin initiation in primary care improves HbA1c levels

The Stepping Up model of care produced a clinically and significantly significant improvement in HbA1c among adults with type 2 diabetes managed in primary care.

Same-day discharge may be safe for patients after percutaneous coronary intervention

Same-day discharge may be safe for patients after percutaneous coronary intervention

Same-day discharge after percutaneous coronary intervention for non-ST-segment elevation acute coronary syndromes was not predictive of 30-day readmission, death, or bleeding.

HPV educational session may boost vaccination rates in high school students

HPV educational session may boost vaccination rates in high school students

The students improved their basic knowledge of HPV and understood the benefits of the HPV vaccine.

Screening for spontaneous preterm birth has low predictive accuracy

Screening for spontaneous preterm birth has low predictive accuracy

Using measurements of vaginal fetal fibronectin levels and cervical length did not indicate spontaneous preterm birth among first-time pregnant women.

Sepsis risk calculator helps decrease antibiotic use in infants

Sepsis risk calculator helps decrease antibiotic use in infants

Data presented at NAPNAP show that an early-onset sepsis calculator can decrease the number of infants who received a sepsis work-up and prophylactic antibiotics.

First-year residents will be able to work 24-hour shifts

First-year residents will be able to work 24-hour shifts

The ACGME announces that residency programs can increase shift hours for first-year residents from 16 to 24 hours.

Antithrombotic drug use linked to higher risk of subdural hematoma

Antithrombotic drug use linked to higher risk of subdural hematoma

A higher incidence of subdural hematomas is associated with the increased use of antithrombotic drugs, particularly vitamin k antagonists among older patients.

FODMAP diet effective for irritable bowel syndrome

FODMAP diet effective for irritable bowel syndrome

Implementation of the FODMAP diet is an effective strategy to manage symptoms of IBS, including bloating and abdominal pain.

Postpartum depression incidence declining

Postpartum depression incidence declining

Reducing postpartum depression involves universal screening and appropriate referral and treatment by clinicians.

Nearly half of all cardiometabolic deaths linked to poor diet

Nearly half of all cardiometabolic deaths linked to poor diet

Suboptimal intake of 10 specific dietary factors is associated with a substantial proportion of deaths due to heart disease, stroke, or type 2 diabetes.

High-dose steroids increase infection risk in pregnant women with inflammatory conditions

High-dose steroids increase infection risk in pregnant women with inflammatory conditions

Risk of serious infections is similar among pregnant women with systemic inflammatory conditions using steroids, non-biologics, and TNF inhibitors.

USPSTF: evidence insufficient for pelvic exams in asymptomatic nonpregnant women

USPSTF: evidence insufficient for pelvic exams in asymptomatic nonpregnant women

The USPSTF concludes that evidence is insufficient to assess the balance of benefits and harms of performing screening pelvic examinations in asymptomatic women for the early detection and treatment of a range of gynecologic conditions.

Ultrasound vs radiology for diagnosing pneumonia

Ultrasound vs radiology for diagnosing pneumonia

Point of care lung ultrasound is an accurate tool for the diagnosis of pneumonia, according to researchers.

ACOG recommends genetic screening in all women before pregnancy

ACOG recommends genetic screening in all women before pregnancy

ACOG recommends that carrier screening should be provided to all women who are pregnant but ideally should be provided to women as they are considering pregnancy.

Managing diabetic retinopathy: ADA releases new position statement

Managing diabetic retinopathy: ADA releases new position statement

The position statement by the ADA incorporates updates in treatment and screening for patients with diabetic retinopathy.

Evaluating abnormal liver chemistries: a clinical guideline

Evaluating abnormal liver chemistries: a clinical guideline

The American College of Gastroenterology has released recommendations of preferred approaches for diagnosing and evaluating patients with abnormal liver test results.

Cystic fibrosis: consensus diagnostic guidelines for clinicians

Cystic fibrosis: consensus diagnostic guidelines for clinicians

The guidelines outline the diagnosis of CF and clarify diagnostic criteria and terminology for other disorders associated with CFTR mutations.

Life expectancy for some may exceed 90 years by 2030

Life expectancy for some may exceed 90 years by 2030

Researchers report that women and men in the United States will have lower life expectancy gains, compared with those in other countries.

Pharmacologic treatment of insomnia: a new clinical practice guideline

Pharmacologic treatment of insomnia: a new clinical practice guideline

The American Academy of Sleep Medicine recommends that the new pharmacologic guidelines be used in conjunction with other AASM guidelines for insomnia.

Stem cell therapy may be effective for multiple sclerosis

Stem cell therapy may be effective for multiple sclerosis

Younger age, relapsing forms of MS, fewer prior immunotherapy treatments, and lower baseline EDSS score were factors associated with better outcomes for stem cell transplantation.

Vitamin D supplementation reduces the risk of acute respiratory tract infection

Vitamin D supplementation reduces the risk of acute respiratory tract infection

Patients receiving vitamin D for deficiency without bolus doses experienced the most benefit.

Proton pump inhibitor use may decrease healthcare visits in GERD patients

Proton pump inhibitor use may decrease healthcare visits in GERD patients

Among GERD patients, the mean annual ARI episode dropped from 4.39 during the year before PPI treatment to 3.89 after treatment with a PPI.

More antimicrobial treatments needed in community-acquired pneumonia

More antimicrobial treatments needed in community-acquired pneumonia

Findings from a US claims-based retrospective study call for more effective antimicrobial treatments for patients with community-acquired pneumonia.

Acute pancreatitis may reveal pancreatic cancer at earlier stage

Acute pancreatitis may reveal pancreatic cancer at earlier stage

Surgical intervention after 24.5 days of acute pancreatitis may be beneficial for reducing postoperative complications.

Opioids for chronic pain: a new clinical guideline from the VA and Department of Defense

Opioids for chronic pain: a new clinical guideline from the VA and Department of Defense

The Veterans Administration and Department of Defense issue a clinical practice guideline regarding opioid therapy for chronic pain in veterans.

Personalized treatment for very early stage hepatocellular carcinoma

Personalized treatment for very early stage hepatocellular carcinoma

Investigators have proposed an algorithm to facilitate the decision-making process of clinical care for patients with very early hepatocellular carcinoma.

2017 Adult immunization schedule released by the CDC

2017 Adult immunization schedule released by the CDC

The ACIP has released the 2017 recommended immunization schedule for adults.

MRI may detect autism before age 1

MRI may detect autism before age 1

MRI scans showed that the brain size of infants grew faster between 12 and 24 months, the same time that behavioral signs of autism appeared.

Apixaban linked to higher rates of stroke than warfarin in patients with atrial fibrillation

Apixaban linked to higher rates of stroke than warfarin in patients with atrial fibrillation

Rivaroxaban once daily and dabigatran twice daily showed evidence of lower thromboembolic rates.

Hepatitis C infection linked to nonhepatic cancers among elderly patients

Hepatitis C infection linked to nonhepatic cancers among elderly patients

HCV infection is associated with cancers such as bile duct and pancreatic cancers and diffuse large B-cell lymphoma.

Noninvasive treatment for low back pain: a new clinical guideline from ACP

Noninvasive treatment for low back pain: a new clinical guideline from ACP

The ACP has released 3 recommendations for the treatment of patients with acute, subacute, and chronic low back pain.

Licorice consumption during pregnancy may be harmful for offspring

Licorice consumption during pregnancy may be harmful for offspring

Girls whose mothers consumed high amounts of licorice during pregnancy have more advanced pubertal maturation at age 12 years.

Prolapse surgery outcomes not improved with transvaginal mesh or biological graft

Prolapse surgery outcomes not improved with transvaginal mesh or biological graft

Using transvaginal mesh and biological graft in prolapse surgery did not improve outcomes of effectiveness, quality of life, or adverse events.

2017 immunization schedule for children and adolescents released by CDC

2017 immunization schedule for children and adolescents released by CDC

The schedule includes new or revised recommendations for several vaccines for children and adolescents.

Radiation exposure and cancer risk from CT screening: a risk-benefit analysis

Radiation exposure and cancer risk from CT screening: a risk-benefit analysis

After 10 years of low-dose CT screening in patients, 1.5 lung cancers and 2.4 major cancers per 10,000 people screened were induced by radiation.

Prestroke psychosocial factors linked to poststroke depression risk in women

Prestroke psychosocial factors linked to poststroke depression risk in women

Women with a good recovery after stroke and a moderate level of optimism had a 0.40‐fold reduction in the odds of developing new-onset poststroke depression.

Atypical antipsychotic therapy with mood stabilizers effective after bipolar episode

Atypical antipsychotic therapy with mood stabilizers effective after bipolar episode

Atypical antipsychotic adjunctive therapy and mood stabilizers may be a more effective treatment than mood stabilizer monotherapy.

NSAID use for respiratory infection increases myocardial infarction risk

NSAID use for respiratory infection increases myocardial infarction risk

NSAID use during ARI was associated with a 3.4-fold increased risk of AMI compared with 2.7-fold increased risk without NSAID use.

CDC expands investigation into Seoul virus outbreak

CDC expands investigation into Seoul virus outbreak

Symptoms of Seoul virus infection typically begin within 1 to 2 weeks after contact with infectious material and include fever, headache, and back pain.

Anxiety and depression may have predictive role in cancer mortality

Anxiety and depression may have predictive role in cancer mortality

Researchers measured vital status records to ascertain death from 16 site-specific malignancies.

Intervention during labor and birth: new recommendations from ACOG

Intervention during labor and birth: new recommendations from ACOG

The ACOG releases an updated committee opinion suggesting that low-risk women can benefit from minimal intervention during labor and delivery.

FDA approves first newborn screening system for rare metabolic disorders

FDA approves first newborn screening system for rare metabolic disorders

The Seeker System is approved to screen for four rare lysosomal storage disorders in newborns.

Death rate high in elderly within 7 days of discharge from emergency department

Death rate high in elderly within 7 days of discharge from emergency department

More than 10,000 Medicare beneficiaries die each year within 7 days of being discharged from emergency departments.

Mortality rate lower in US patients treated by foreign-educated internists

Mortality rate lower in US patients treated by foreign-educated internists

Researchers observed a somewhat lower mortality among patients treated by international graduates.

Electronic cigarette use linked to higher CVD risk

Electronic cigarette use linked to higher CVD risk

Electronic cigarettes cause an imbalance of cardiac autonomic tone and increased oxidative stress, which may increase cardiovascular risk.

High-potency statins increase hospitalization for community-acquired pneumonia

High-potency statins increase hospitalization for community-acquired pneumonia

Higher-potency statins increased hospitalization for community-acquired pneumonia compared with lower-potency statins.

Recurrent pneumonia resulting from misdiagnosed endobronchial suture—a case synopsis

Recurrent pneumonia resulting from misdiagnosed endobronchial suture—a case synopsis

Endobronchial suture should be considered in patients with recurrent pneumonia that is unresponsive to medical therapy.

Pneumococcal vaccination reduces pneumonia risk in COPD patients

Pneumococcal vaccination reduces pneumonia risk in COPD patients

Polyvalent pneumococcal vaccines offered protection against community-acquired pneumonia in COPD patients.

Meal timing and frequency in CVD prevention: an AHA scientific statement

Meal timing and frequency in CVD prevention: an AHA scientific statement

The AHA found that irregular eating patterns are less ideal for maintaining body weight and cardiometabolic health.

Pneumonia vaccine may not be effective in rheumatoid arthritis patients

Pneumonia vaccine may not be effective in rheumatoid arthritis patients

The PPSV23 vaccine may not prevent pneumonia in patients with rheumatoid arthritis.

VA lung cancer screening program finds high rate of incidental findings, low cancer detection rate

VA lung cancer screening program finds high rate of incidental findings, low cancer detection rate

An estimated 900,000 veterans of a population of 6.7 million VHA patients met the criteria for LCS.

Diabetes without insulin may not increase thromboembolic risk in atrial fibrillation

Diabetes without insulin may not increase thromboembolic risk in atrial fibrillation

Diabetes without insulin did not appear to increase thromboembolic risk in patients with atrial fibrillation treated with anticoagulation.

Thyroid hormone treatment linked to reduced risk of pregnancy loss in subclinical hypothyroidism

Thyroid hormone treatment linked to reduced risk of pregnancy loss in subclinical hypothyroidism

Treatment is associated with decreased loss of pregnancy among women with subclinical hypothyroidism.

CDC tips for prediabetes prevention and treatment

CDC tips for prediabetes prevention and treatment

Prediabetes does not always show clear symptoms; however, it can lead to type 2 diabetes, heart disease, or stroke.

Sepsis and septic shock: new guidelines for clinical management

Sepsis and septic shock: new guidelines for clinical management

Updated international guidelines for managing sepsis and septic shock have been released by the Society of Critical Care Medicine and European Society of Intensive Care Medicine.

CDC: Two-thirds of US youth consume at least one sugar-sweetened beverage per day

CDC: Two-thirds of US youth consume at least one sugar-sweetened beverage per day

Overall, US youth consumed an average 143 kcal from sugar-sweetened beverages, with boys consuming a higher percentage of calories than girls.

Accuracy of prediabetes screening tests is low

Accuracy of prediabetes screening tests is low

Fasting glucose is specific but not sensitive, and HbA1c is neither sensitive nor specific.

Earwax: a clinical practice guideline for management and treatment

Earwax: a clinical practice guideline for management and treatment

The guideline aims to help clinicians identify patients with cerumen impaction who may benefit from intervention.

USPSTF: Evidence lacking for obstructive sleep apnea screening

USPSTF: Evidence lacking for obstructive sleep apnea screening

The USPSTF found that there is uncertainty about the accuracy of screening tools for obstructive sleep apnea in adults.

Efficacy of renin angiotensin system inhibitors for coronary artery disease

Efficacy of renin angiotensin system inhibitors for coronary artery disease

RASIs reduced cardiovascular events and death only when compared with placebo but not when compared with active controls.

One-third of asthma patients may be misdiagnosed

One-third of asthma patients may be misdiagnosed

About one-third of adults with physician-diagnosed asthma in the last 5 years may not have a current diagnosis.

FDA approves Trulance for chronic idiopathic constipation treatment

FDA approves Trulance for chronic idiopathic constipation treatment

Trulance has been approved for the treatment of chronic idiopathic constipation in adults.

Safety alert issued for LIFEPAK 1000 defibrillator

Safety alert issued for LIFEPAK 1000 defibrillator

The device has shut down due to an intermittent connection between the battery and electrical contacts.

FDA and EPA release final recommendations for fish consumption in pregnant women

FDA and EPA release final recommendations for fish consumption in pregnant women

For adults, the recommended serving size of fish is 4 ounces, while servings for children should be smaller based on their age and calorie intake.

LASIK surgery: a mixed bag of results?

LASIK surgery: a mixed bag of results?

Data from the PROWL studies show that most patients are satisfied with LASIK surgery, although many patients experience new symptoms.

Hypertension treatment in older adults: a new clinical practice guideline

Hypertension treatment in older adults: a new clinical practice guideline

The ACP and the AAFP has released a joint recommendation for the pharmacologic treatment of hypertension in adults aged 60 years and older.

Migraine increases stroke risk in surgical patients

Migraine increases stroke risk in surgical patients

Surgical patients with a history of migraine have an increased risk of perioperative ischemic stroke and a higher 30-day hospital readmission rate.

Lithium side effects and management strategies

Lithium side effects and management strategies

The declining rates for lithium use are linked to the burden of side effects and toxicity associated with the drug.

"Weekend warrior" activity reduces all-cause mortality risk

"Weekend warrior" activity reduces all-cause mortality risk

Individuals who perform their physical activity in 1 or 2 sessions during the week can still reduce their risk of mortality.

Depression literacy higher in women and linked to medication adherence

Depression literacy higher in women and linked to medication adherence

Some aspects of depression literacy were lower among patients with depression.

Monitoring asthma control in children: AAP recommendations for clinicians

Monitoring asthma control in children: AAP recommendations for clinicians

Recent advances in measuring asthma control tools have enhanced ongoing assessment and monitoring of asthma.

Drug and alcohol use associated with higher risk of adolescent firearm homicide

Drug and alcohol use associated with higher risk of adolescent firearm homicide

Substance use is associated with an increased risk of adolescent firearm homicide.

USPSTF recommends folic acid for all women who may become pregnant

USPSTF recommends folic acid for all women who may become pregnant

The USPSTF recommends folic acid supplement for all women who are capable of pregnancy or who are planning to become pregnant.

US spending on health care substantially increases, led by diabetes, ischemic heart disease

US spending on health care substantially increases, led by diabetes, ischemic heart disease

Spending on diabetes, IHD, and lower back and neck pain account for the highest amounts of spending by disease category.

NIH releases addendum guidelines to prevent peanut allergies through early introduction

NIH releases addendum guidelines to prevent peanut allergies through early introduction

The NIAID has issued addendum guidelines regarding the early introduction of peanut-containing foods to infants at risk for peanut allergies.

COPD exacerbations reduced with budesonide/formoterol treatment

COPD exacerbations reduced with budesonide/formoterol treatment

Budesonide/formoterol treatment decreased exacerbations in COPD after 3 months.

Patients with chronic diseases are frequently overly optimistic about life expectancy

Patients with chronic diseases are frequently overly optimistic about life expectancy

Self-estimated life expectancy rates may differ from clinician-estimated rates of survival.

Statin prescription rates lower among younger adults with severe dyslipidemia

Statin prescription rates lower among younger adults with severe dyslipidemia

Prescription rates for statins were dependent on age among patients with severe dyslipidemia.

Morning symptoms in COPD linked to limited physical activity

Morning symptoms in COPD linked to limited physical activity

Many patients with COPD report morning symptoms that are negatively associated with physical activity.

Fish oil, aspirin ineffective for reducing arteriovenous fistula failure

Fish oil, aspirin ineffective for reducing arteriovenous fistula failure

The study suggests that neither fish oil nor aspirin can be recommended for the prevention of AVF failure.

Psychiatric, behavioral conditions linked to future long-term opioid use

Psychiatric, behavioral conditions linked to future long-term opioid use

Patients diagnosed with a prior psychiatric condition have increased odds of long-term opioid receipt than patients without these conditions.

Updated guideline for oral pharmacologic treatment of type 2 diabetes

Updated guideline for oral pharmacologic treatment of type 2 diabetes

The ACP has updated the 2012 guideline to provide clinical recommendations of oral pharmacologic treatment of type 2 diabetes.

FDA approves first continuous glucose monitoring system to replace fingerstick test in diabetes

FDA approves first continuous glucose monitoring system to replace fingerstick test in diabetes

The FDA has approved a continuous glucose monitoring system to replace fingerstick blood sugar testing in patients with diabetes.

American Urological Association issues guideline for male urethral stricture

American Urological Association issues guideline for male urethral stricture

The guidelines provide a clinical framework for the diagnosis and treatment of male urethral stricture.

Mortality rates remain high among HIV-positive patients

Mortality rates remain high among HIV-positive patients

The HIV-positive population of the United Kingdom has a higher risk of death than the general population, despite availability of free treatment and care.

In-utero MRI more accurate than ultrasound for diagnosing fetal brain abnormalities

In-utero MRI more accurate than ultrasound for diagnosing fetal brain abnormalities

This finding suggests that any fetus with a suspected brain abnormality on ultrasound should have iuMRI to better inform counseling and management decisions.

"Zombie" outbreak in New York City caused by ultrapotent cannabinoid use

"Zombie" outbreak in New York City caused by ultrapotent cannabinoid use

The potency of synthetic cannabinoids is consistent with strong depressant effects that account for "zombie-like" behavior.

FDA bans powdered surgeon's and patient examination gloves

FDA bans powdered surgeon's and patient examination gloves

The FDA has issued a final ruling to ban powdered surgeon's gloves, powdered patient examination gloves, and absorbable powder for lubricating a surgeon's glove.

USPSTF recommends against routine serologic screening for genital herpes simplex virus

USPSTF recommends against routine serologic screening for genital herpes simplex virus

The USPSTF has released a final recommendation against routine serologic screening for genital herpes simplex virus infection.

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