Web Exclusives

Presence, pain intensity, itch may be a sign of skin cancer

Presence, pain intensity, itch may be a sign of skin cancer

The prevalence of itch was 36.9%, and the prevalence of pain was 28.2% across all skin cancer, but these symptoms were mainly absent in melanomas

Travel warning issued after Ebola outbreak worsens in West Africa

Travel warning issued after Ebola outbreak worsens in West Africa

Agency also plans to send 50 more experts to the affected countries.

COPD costs projected to reach $49B in 2020

COPD costs projected to reach $49B in 2020

Nearly 13 million U.S. adults had chronic obstructive pulmonary disease in 2011, and 24 million adults had signs of impaired lung function.

Dieting young triggers greater health complications later in life

Dieting young triggers greater health complications later in life

In young women, dieting at a younger age predicts obesity, extreme weight control measures, and alcohol misuse.

IOM: GME funding system needs an overhaul

IOM: GME funding system needs an overhaul

Medicare should continue to support graduate medical education, contingent on value.

Stroke incidence, mortality declines in senior patients

Stroke incidence, mortality declines in senior patients

Incident strokes in the Medicare population aged ≥65 years decreased by approximately 40% over the last two decades.

Dietary salt intake linked to CVD in patients with T2D

Dietary salt intake linked to CVD in patients with T2D

Sodium reduction has been encouraged in guidelines for diabetes care in many countries.

New hepatitis C treatments promising

New hepatitis C treatments promising

Combined simeprevir and sofosbuvir, and an all-oral therapy with daclatasvir plus asunaprevir showed sustained virological responses.

Language barriers not associated with diabetes complications

Language barriers not associated with diabetes complications

A study of immigrant patients in Canada suggests that language barriers don't impact the risk for diabetes complications in non-native patients.

Hormonal birth control increases gestational diabetes risk

Hormonal birth control increases gestational diabetes risk

Women using barrier contraception and those using no contraception were at lower risk compared with those using hormonal contraception.

Post-cardiac-surgery stroke predictors identified

Post-cardiac-surgery stroke predictors identified

Most patients undergoing cardiac surgery have conditions such as hypertension, diabetes and atrial fibrillation.

Obesity, gestational weight gain associated with child asthma risk

Obesity, gestational weight gain associated with child asthma risk

Each 1-kg/m2 increase in maternal BMI was associated with a 2% to 3% increase in the odds of childhood asthma.

PCPs aren't recommending the HPV vaccine enough

PCPs aren't recommending the HPV vaccine enough

1/3 of parents of girls reported that their child's clinician had failed to recommended the HPV vaccination during office visits.

FDA approves extended-release painkiller

FDA approves extended-release painkiller

The medication is designed to deter abuse of the drug by snorting or injection.

Smoking during pregnancy linked to child ADHD

Smoking during pregnancy linked to child ADHD

Maternal and paternal smoking during pregnancy was associated with higher ADHD risk, but the association was stronger for females.

Probiotics may lower blood pressure

Probiotics may lower blood pressure

Effect appears to be greater when baseline blood pressure is elevated.

Antibiotics Rxs more common than antivirals for flu

Antibiotics Rxs more common than antivirals for flu

Among patients diagnosed with PCR-confirmed influenza, more receive antibiotic prescriptions than antivirals.

Clinicians' role in HIV prevention to expand

Clinicians' role in HIV prevention to expand

Combining behavioral and biomedical advancements may be the best prevention method for patients at risk of HIV.

Long-term weight loss decreases diabetes risk

Long-term weight loss decreases diabetes risk

Steady weight-loss over two years was a stronger predictor of reducing diabetes risk, compared with six months of weight-loss.

Tech program helps PCPs identify undiagnosed hypertension

Tech program helps PCPs identify undiagnosed hypertension

Hypertension is the leading modifiable risk factor for coronary artery disease, stroke, heart failure, and chronic kidney disease.

Experts urge reconsidering lifetime ban on blood donations from gay men

Experts urge reconsidering lifetime ban on blood donations from gay men

Citing new technologies and legal protections, the lifetime ban on blood donations from gay men should be reconsidered.

Drug-resistant CRE increasing in southeastern U.S. hospitals

Drug-resistant CRE increasing in southeastern U.S. hospitals

Greater use of broad-spectrum antibiotics, increased transmission from long-term acute care facilities associated with increases in carbapenem-resistant Enterobacteriaceae.

Medical malpractice filings drop 40% in Pennsylvania

Medical malpractice filings drop 40% in Pennsylvania

Two new state rulings are credited with the drop in malpractice filings.

Follow-up care improves heart-failure outcomes

Follow-up care improves heart-failure outcomes

Heart failure patients receiving continuity care after ED discharge were less likely to experience hospitalization or death.

CDC: Not enough teens are being tested for HIV

CDC: Not enough teens are being tested for HIV

Female and black patients were more likely to be tested for sexually transmitted diseases compared with males.

Patients may not need to fast for cholesterol tests

Patients may not need to fast for cholesterol tests

Agencies should consider re-evaluating the recommendation that patients fast before obtaining a lipid panel.

Electronic communications increase PCP visits for diabetes

Electronic communications increase PCP visits for diabetes

A 10% increase in secure message threads and telephone encounters correlated with 1.25% and 2.74% increases in office visits, respectively.

Delayed retirement has slowed predicted nursing shortage

Delayed retirement has slowed predicted nursing shortage

The economic recession and the influx of new nursing students has slowed the predicted nursing shortage in the United States.

Testicular cancer risk up in Hispanic patients

Testicular cancer risk up in Hispanic patients

A 58% increase in incidence rate per 100,000 has been noted from 1992 to 2010.

Niacin, laropiprant may not decrease vascular risk

Niacin, laropiprant may not decrease vascular risk

Adverse effects have been found in 34.2% and 32.5% of patients prescribed extended-release niacin.

Simplified approach to aspirin for heart risk prevention

Simplified approach to aspirin for heart risk prevention

Recommend aspirin for all high-risk patients without an increased risk of bleeding.

Stress, hostility increase stroke risk

Stress, hostility increase stroke risk

Correlations seen in middle-aged and older adults, even after adjustment for risk factors.

Psoriasis may be triggered by nerve cells responsible for feeling pain

Psoriasis may be triggered by nerve cells responsible for feeling pain

Researchers are investigating ways to mediate the interactions between immune cells and nerves.

Should you advise patients to eat organic?

Should you advise patients to eat organic?

A new study suggests organically grown produce and grains contain less cadmium and more antioxidants.

Behavioral weight-loss program may reduce hot flashes

Behavioral weight-loss program may reduce hot flashes

Hot flash reduction was reported as a motivator for weight loss.

Detailed screening tools help diagnose PsA

Detailed screening tools help diagnose PsA

PsA prevalence based on the patient-administered screening tools was 12% to 16% higher compared with rheumatologists' diagnosis.

Polio vaccine boosts kids' intestinal immunity

Polio vaccine boosts kids' intestinal immunity

Single dose improves intestinal immunity for children previously vaccinated with oral polio vaccine.

Routine NSAID use in females ups cardiovascular risks

Routine NSAID use in females ups cardiovascular risks

Risk up with regular NSAID use, selective cox-2 inhibitor use, agents with cox-2>cox-1 inhibition.

Update: 444,000 patients die each year due to medical errors

Update: 444,000 patients die each year due to medical errors

Medical errors are the third leading cause of death in the United States.

Drinking less alcohol benefits heart health

Drinking less alcohol benefits heart health

Patients with the rs1229984 gene variant tended to drink less and had healthier hearts.

Obesity linked to higher total mortality

Obesity linked to higher total mortality

Increasing BMI was associated with increasing number of years of life lost in class III obese patients.

Newly discovered protein may be key to psoriasis Tx

Newly discovered protein may be key to psoriasis Tx

AhR signaling in nonhematopoietic cells plays a pivotal role in prevention of excessive skin inflammation.

Kidney donation OK for select seniors

Kidney donation OK for select seniors

The combined outcome of death/cardiovascular disease was not significantly different between donors and nondonors.

WHO recognizes psoriasis as chronic condition

WHO recognizes psoriasis as chronic condition

The resolution sends a powerful global message about the serious nature of the disease.

Violence 'accepted' in the ED

Violence 'accepted' in the ED

Barriers to decreasing violence included limited recognition of high-risk patients and culture of acceptance of violence.

Poverty linked to increased PAD prevalence

Poverty linked to increased PAD prevalence

Patients who were in the lowest six poverty-income ratios were at a two-fold higher risk of peripheral artery disease.

Dupilumab effective for atopic dermatitis

Dupilumab effective for atopic dermatitis

A 50% reduction in the Eczema Area and Severity Index score (EASI-50) seen in 85% of patients in the dupilumab group.

Secukinumab effective for plaque psoriasis

Secukinumab effective for plaque psoriasis

Data from two randomized trials demonstrate efficacy of secukinumab versus placebo.

Sibling obesity better predicts child obesity

Sibling obesity better predicts child obesity

Siblings of the same gender showed stronger patterns than between siblings of different genders.

Long-term use of hypertension meds linked to psoriasis

Long-term use of hypertension meds linked to psoriasis

Psoriasis flares were seen in female patients prescribed hypertension medication.

Healthy lifestyle choices lower future CAD risk

Healthy lifestyle choices lower future CAD risk

Low alcohol intake, healthy diet, low and physical activity decreased coronary artery calcification after 20 years.

Varenicline plus nicotine replacement improves quit rates

Varenicline plus nicotine replacement improves quit rates

The combination treatment was associated with a higher continuous abstinence rate at 12 weeks and at 24 weeks.

Is a blood test that can predict Alzheimer disease on the way?

Is a blood test that can predict Alzheimer disease on the way?

Researchers have identified 10 proteins in the blood that may be predictors of Alzheimer disease.

Vaccinations safe for U.S. children

Vaccinations safe for U.S. children

Rare adverse events that may be associated with vaccination should be weighed against the protective benefits vaccines provide.

Insulin resistance increases T2D risk, independent of BMI

Insulin resistance increases T2D risk, independent of BMI

Genetic score for insulin resistance linked to lower BMI and adiposity, incident type 2 diabetes.

Malnutrition increases hypertension risk later in life

Malnutrition increases hypertension risk later in life

Patients who survived early malnutrition are reported to have weakened cardiovascular structure and function.

Aerobic exercise benefits patients with Parkinson disease

Aerobic exercise benefits patients with Parkinson disease

Walking 45 minutes three days per week improved motor function and quality of life in patients with Parkinson disease.

Fish oil, vitamin D may offer psoriasis relief

Fish oil, vitamin D may offer psoriasis relief

Studies suggest that omega-3 fatty acids may be beneficial as monotherapy or in combination with other therapeutic regimens.

No link between testosterone therapy, heart attack

No link between testosterone therapy, heart attack

High-risk patients treated with testosterone had a lower rate of heart attacks compared with patients who did not receive treatment.

Novel psoriasis drug on the horizon

Novel psoriasis drug on the horizon

Promising investigational oral drug may offer fewer side effects than current therapies.

Injury and violence leading causes of death among young adults

Injury and violence leading causes of death among young adults

The CDC urges medical providers to frame injuries and violence as preventable and identify evidence-based interventions.

Be cautious of substance abuse in kids with ADHD

Be cautious of substance abuse in kids with ADHD

Kids diagnosed with attention-deficit/hyperactivity disorder are at higher risk for developing substance use disorders.

CDC: Beware of antibiotic resistance in foodborne pathogens

CDC: Beware of antibiotic resistance in foodborne pathogens

The rate of resistance to quinolone drugs in Salmonella typhi rose to 68% in 2012.

Mental stress linked to adverse CV events in CAD patients

Mental stress linked to adverse CV events in CAD patients

Risk of adverse cardiovascular events is approximately doubled in patients with coronary artery disease.

New guidelines recommend against pelvic screening

New guidelines recommend against pelvic screening

Pelvic examinations had a predictive value of less than 4% for detecting ovarian cancer.

Opioid prescribing rates vary drastically by region

Opioid prescribing rates vary drastically by region

The CDC noted a positive trend in decreasing overdose deaths, but urges clinicians to continue safe prescribing habits.

Chronic kidney disease linked to some cancers

Chronic kidney disease linked to some cancers

A history of reduced kidney function may put an individual at greater risk for developing renal and urothelial cancers.

Brodalumab improves psoriatic arthritic symptoms

Brodalumab improves psoriatic arthritic symptoms

Improvement rates were similar among treatment-experienced patients and those naive to biologic treatment.

Large malpractice award may challenge Wisconsin damages cap

Large malpractice award may challenge Wisconsin damages cap

A Milwaukee patient was awarded $25 million after loss of all four limbs due to undiagnosed group A streptococcal infection.

FDA approves inhaled insulin drug Afrezza

FDA approves inhaled insulin drug Afrezza

Afrezza can be used for the improvement of glycemic control in adult patients with diabetes mellitus.

CKD risk factors identified years before diagnosis

CKD risk factors identified years before diagnosis

Hypertension, obesity, diabetes and other risk factors were found in patients with chronic kidney disease years before diagnosis.

Shared decision-making in CA screenings falls short

Shared decision-making in CA screenings falls short

Less than 50% of survey participants reported shared-decision making when considering cancer-screening options.

Lower ART toxicity improves HIV positive life expectancy rates

Lower ART toxicity improves HIV positive life expectancy rates

A simulation model predicting the rate of new HIV medications suggests newer drugs with lower toxicity levels may increase life expectancy.

Television linked to all-cause mortality

Television linked to all-cause mortality

Participants reporting three or more versus less than one hour/day of television viewing had a more than two-fold increase in mortality.

PCP visits reduce surgical readmission rates

PCP visits reduce surgical readmission rates

Readmission risk was significantly reduced with early PCP follow-up among patients who underwent high risk surgery.

1 in 10 U.S. beaches pose health hazards

1 in 10 U.S. beaches pose health hazards

Great Lakes, Gulf states worst offenders in coastal and lake beach pollution.

New testing technology closes gaps in HIV prevention

New testing technology closes gaps in HIV prevention

New CDC recommendations for laboratory testing can identify HIV infection weeks earlier.

Pertussis still common in kids with persistent cough

Pertussis still common in kids with persistent cough

Among kids at several UK general practices, 20% had evidence of recent pertussis infection.

Calcium, vitamin D benefit pregnant gestational-diabetes patients

Calcium, vitamin D benefit pregnant gestational-diabetes patients

Glucose metabolism, lipid profiles, and biomarkers of oxidative stress improvements were seen in patients assigned supplementation.

Upping calcium decreases CRC mortality rates

Upping calcium decreases CRC mortality rates

Postdiagnosis milk intake, but not vitamin D intake, was inversely associated with all-cause mortality.

Do CDC anti-smoking ads impact cessation rates?

Do CDC anti-smoking ads impact cessation rates?

The CDC reports that their 2012 anti-smoking campaign generated more than 100,000 additional calls to the agency's quit line.

Expert urges caution in considering lung CA screening options

Expert urges caution in considering lung CA screening options

Decision not to include low-dose computed tomography screening for lung cancer under Medicare may affect lung cancer disparity rates.

BRCA gene testing impacts surgery decisions

BRCA gene testing impacts surgery decisions

In women with newly diagnosed breast cancer, the optimal time for referral to cancer genetic specialists is unknown.

FDA approves tedizolid phosphate for skin infections

FDA approves tedizolid phosphate for skin infections

The antibiotic is designed to treat infections including MRSA.

Prior hospitalizations may predict stroke readmission

Prior hospitalizations may predict stroke readmission

Readmitted patients were more likely to have more than two hospitalizations in the year prior.

Birth control use differs between race, age, and ethnicity

Birth control use differs between race, age, and ethnicity

Interventions to improve contraceptive use should focus on younger female patients.

CDC: 1 in 10 pregnant patients develops gestational diabetes

CDC: 1 in 10 pregnant patients develops gestational diabetes

Gestational diabetes incidence was found to vary by geographical area, and may be associated with obesity levels.

Coping strategies help families of teens with autism adapt

Coping strategies help families of teens with autism adapt

Greater impact of daily stressors, behavioral problems and worry about the future associated with more difficulty adapting.

Educate pregnant women to prevent congenital CMV

Educate pregnant women to prevent congenital CMV

Despite being the leading cause of mental retardation and disability in children, there are currently no national public awareness campaigns on CMV.

Lorcaserin improved glycemic control regardless of weight loss

Lorcaserin improved glycemic control regardless of weight loss

Lorcaserin is more effective in helping obese patients with type 2 diabetes achieve glycemic control than diet and exercise alone.

ImPACT program may aid concussion detection in student athletes

ImPACT program may aid concussion detection in student athletes

The intervention is designed to be administered immediately after a sports injury, in order to evaluate for potential cognitive changes.

Healthy Lifestyle Program effective for weight loss

Healthy Lifestyle Program effective for weight loss

An adaptable office-based lifestyle and diet intervention helped patients effectively lose weight.

Having a survivorship plan aids NP-provided cancer care

Having a survivorship plan aids NP-provided cancer care

Coordinating with a cancer survivor's oncology team and understanding the survivorship plan can help ease care transitions.

Educating at-risk patients reduces diabetes risk factors

Educating at-risk patients reduces diabetes risk factors

A reduction in weight and glycohemoglobin was seen in patients that completed a diabetes prevention course.

Techniques aid safe opioid prescribing

Techniques aid safe opioid prescribing

Drug screening, risk stratification and pharmacogenetic testing should be used to guide prescribing habits.

Majority of allergies can be treated in primary care

Majority of allergies can be treated in primary care

With a dwindling number of practicing allergists, primary-care clinicians should be prepared to identify and treat allergic conditions.

NP-led acute care teams improve inpatient care

NP-led acute care teams improve inpatient care

Better care coordination may help reduce patient complications and length of stay.

Culture shift critical to achieving evidence-based practice

Culture shift critical to achieving evidence-based practice

Mentors, infrastructure and reward system are essential components in successfully transitioning existing health care models to evidence-based practice.

Pharmacology update: 2014 drug trends

Pharmacology update: 2014 drug trends

More orphan drugs approved in recent years are filling the need for treating rare disease and medical conditions.

How to negotiate a fair NP contract

How to negotiate a fair NP contract

Prepare, probe and propose when discussing terms of employment.