Web Exclusives

Interrelationship Between Celiac Disease, Self-Reported Wheat Sensitivity, and Functional GI Disorders

Interrelationship Between Celiac Disease, Self-Reported Wheat Sensitivity, and Functional GI Disorders

Individuals with clinically diagnosed celiac disease are at greater risk for chronic gastrointestinal symptoms, possibly fitting modified Rome criteria for irritable bowel syndrome and functional dyspepsia.

Fidaxomicin Effective for Long-Term Cure of Clostridium difficile

Fidaxomicin Effective for Long-Term Cure of Clostridium difficile

Fidaxomicin demonstrated the strongest evidence for being the most effective treatment in providing a long-term cure for C difficile infection.

Cardiac Pathology in SUDEP Compared With Sudden Arrhythmic or Traumatic Deaths

Cardiac Pathology in SUDEP Compared With Sudden Arrhythmic or Traumatic Deaths

Causes of death in patients with epilepsy were assessed to determine the presence of cardiac pathology.

Skin Cancer Education May Improve Sun Protection Practices Among Organ Transplant Recipients

Skin Cancer Education May Improve Sun Protection Practices Among Organ Transplant Recipients

The use of multiple sun protection measures was defined as the use of 2 or more of these measures more than 50% of the time when the individual was outdoors.

Lack of Vaccination in High-Exempt Areas Linked to Medical Distrust

Lack of Vaccination in High-Exempt Areas Linked to Medical Distrust

Exemption from vaccination is common in Arizona school districts due to lack of trust in medical establishments.

Food-Induced Anaphylaxis Risk in Infants, Children

Food-Induced Anaphylaxis Risk in Infants, Children

Respiratory symptoms were more common in older children compared with infants who presented with food-induced anaphylaxis.

Preeclampsia With Severe Features Increases Risk for Cardiac Abnormalities

Preeclampsia With Severe Features Increases Risk for Cardiac Abnormalities

Women with preeclampsia with severe features had increased right ventricular systolic pressure and decreased global right ventricular longitudinal systolic strain.

Link Between Bullous Pemphigoid and Dipeptidyl Peptidase-4 Inhibitors

Link Between Bullous Pemphigoid and Dipeptidyl Peptidase-4 Inhibitors

The relationship between bullous pemphigoid and dipeptidyl peptidase-4 inhibitors in type 2 diabetes.

Single High-Dose Liposomal Amphotericin B Effectively Treats HIV-Associated Cryptococcal Meningitis

Single High-Dose Liposomal Amphotericin B Effectively Treats HIV-Associated Cryptococcal Meningitis

Single high-dose liposomal amphotericin B (L-AmB) is non-inferior to daily dosed L-AmB at the standard dose in treatment of fungal clearance in HIV-associated cryptococcal meningitis.

Therapy Focusing on Mindfulness, Interoception Improves Outcomes for Women With Substance Use Disorder

Therapy Focusing on Mindfulness, Interoception Improves Outcomes for Women With Substance Use Disorder

These findings are consistent with emerging neurocognitive models linking interoception to emotion regulation and related health outcomes, providing valuable input in improving substance use disorder treatment.

Guidelines for Management of Hypothalamic-Pituitary, Growth Disorders in Childhood Cancer Survivors

Guidelines for Management of Hypothalamic-Pituitary, Growth Disorders in Childhood Cancer Survivors

The Endocrine Society, European Society of Endocrinology, and Pediatric Endocrine Society issue guidelines for the management of hypothalamic-pituitary and growth disorders in childhood cancer survivors.

Chemotherapy With Bevacizumab May Improve Some Ovarian Cancer Outcomes, Worsen Others

Chemotherapy With Bevacizumab May Improve Some Ovarian Cancer Outcomes, Worsen Others

First-line chemotherapy in combination with bevacizumab, compared with chemotherapy alone, may benefit patients with ovarian cancer and elevated neutrophil-to-lymphocyte ratios.

Emergency Physicians Offer Recommendations for Identifying and Managing Opioid Use Disorder

Emergency Physicians Offer Recommendations for Identifying and Managing Opioid Use Disorder

American emergency medicine physicians have been taking measures to address the ongoing opioid crisis, which affects emergency departments throughout the country.

Radiofrequency Denervation Efficacious in Treating Thoracic Zygapophyseal Joint Pain

Radiofrequency Denervation Efficacious in Treating Thoracic Zygapophyseal Joint Pain

Radiofrequency denervation, typically used to treat lumbar and cervical zygapophyseal joint pain, has shown efficacy in treating thoracic zygapophyseal joint pain.

Is New Surveillance Monitoring Required for Enterococcal Oxazolidinone Resistance?

Is New Surveillance Monitoring Required for Enterococcal Oxazolidinone Resistance?

A study was conducted to evaluate the oxazolidinone resistance mechanisms of enterococci bacteria.

Progress Report in Cancer Control: How Are We Doing?

Progress Report in Cancer Control: How Are We Doing?

An analysis of population data on cancer incidence, survival, and mortality revealed that early interventions and improvements to treatments contributed to a 26% decline in cancer deaths from 1991 to 2015.

No Difference in CEA vs CA125/CEA Ratio for Identifying Ovarian Masses

No Difference in CEA vs CA125/CEA Ratio for Identifying Ovarian Masses

No significant difference was identified in combination CA125/CEA ratio vs CEA alone in distinguishing ovarian neoplasms from ovarian metastases.

Avastin Plus ChemoTx Approved for Advanced Ovarian Cancer After Resection

Avastin Plus ChemoTx Approved for Advanced Ovarian Cancer After Resection

Study patients who received Avastin plus chemotherapy followed by Avastin alone, had a greater median PFS vs patients who received chemotherapy alone (18.2 months vs 12 months; hazard ratio [HR] 0.62, 95% CI, 0.52-0.75; P<.0001).

Overuse of Neuroimaging in the Emergency Department Reported for Pediatric Headache

Overuse of Neuroimaging in the Emergency Department Reported for Pediatric Headache

Investigators examined rates, predictors, and outcomes of neuroimaging in pediatric and adolescent patients who presented to the ED with a headache.

Differences Between Cyclothymic Disorder and Unspecified Bipolar Disorder in Youth May Indicate Course of Disorder

Differences Between Cyclothymic Disorder and Unspecified Bipolar Disorder in Youth May Indicate Course of Disorder

Investigators sought to determine the differences between youth with cyclothymic disorder and bipolar disorder not otherwise specified.

Pain Societies Issue Guidelines on Use of Ketamine for the Management of Acute Pain

Pain Societies Issue Guidelines on Use of Ketamine for the Management of Acute Pain

Consensus guidelines regarding the use of ketamine for the management of acute pain have been approved.

Acute Coronary Syndrome Risk Elevated in Siblings of Patients With RA

Acute Coronary Syndrome Risk Elevated in Siblings of Patients With RA

Siblings of patients with rheumatoid arthritis appear to have an increased risk for acute coronary syndrome, which suggests there is a shared susceptibility between the 2 conditions.

Otitis Media-Related Ambulatory Visits Declined After Pneumococcal Conjugate Vaccine

Otitis Media-Related Ambulatory Visits Declined After Pneumococcal Conjugate Vaccine

The administration of PCV7 and PCV13 reduced the number of ambulatory visits for otitis media in pediatric patients.

Menopause Transition Often Prompts Changes in Migraine Pattern, Characteristics

Menopause Transition Often Prompts Changes in Migraine Pattern, Characteristics

This retrospective study sought to assess migraine patterns in 69 menopausal women between ages 40 and 60 who were treated at Partners Healthcare Hospitals for concurrent migraine headache.

fMRI Evidence for Social Motivation Hypothesis of Autism

fMRI Evidence for Social Motivation Hypothesis of Autism

These data show that ASD may arise from an early neurobiological difference in response to rewarding social stimuli, which could result in reduced social motivation.

Retinal Nerve Fiber Layer Thickness May Be Associated With Cognitive Function

Retinal Nerve Fiber Layer Thickness May Be Associated With Cognitive Function

Thinning of the retinal nerve fiber layer has been linked to worsening cognitive function and may be valuable in identifying individuals who may be at risk for cognitive decline.

Blister Packs for Several Meds Recalled Due to Risk of Harm to Children

Blister Packs for Several Meds Recalled Due to Risk of Harm to Children

The recall affects approximately 470,000 units that include drugs packaged with 3 to 10 tablets per blister card. The blister packs were developed for use in hospitals, however some were sent to retail pharmacies and were likely dispensed for in-home use.

FDA Takes Steps to Reconcile Needs of Patients With Chronic Pain, Efforts to Curb Opioid Epidemic

FDA Takes Steps to Reconcile Needs of Patients With Chronic Pain, Efforts to Curb Opioid Epidemic

A panel discussion event held at the US Food and Drug Administration gathered patients with chronic pain and FDA officials, to reconcile concerns around prescriptions of opioid medications with the needs of these patient populations.

Reproductive Dysfunction Risk in Women Taking Long-Term Opioids for Musculoskeletal Pain

Reproductive Dysfunction Risk in Women Taking Long-Term Opioids for Musculoskeletal Pain

Women prescribed long- vs short-term opioids for chronic musculoskeletal pain may be at increased risk for menopause and abnormal menstruation.

Mirvetuximab Gets Fast Track Status for Platinum-Resistant Ovarian Cancer

Mirvetuximab Gets Fast Track Status for Platinum-Resistant Ovarian Cancer

Mirvetuximuab soravtansine uses a humanized FRα-binding antibody to target antibody-drug conjugates specifically to FRα-expressing cancer cells and a potent anti-tumor agent, DM4, to kill the targeted cancer cells.

Continuous Subcutaneous Insulin Infusion May Reduce Basal Hyperglycemia in T2D

Continuous Subcutaneous Insulin Infusion May Reduce Basal Hyperglycemia in T2D

Patients with type 2 diabetes who were initially treated with multiple daily injections were assessed before and after switching to continuous subcutaneous insulin infusion.

New App Lets Consumers Order STD Tests and Get Treatment via Telemedicine

New App Lets Consumers Order STD Tests and Get Treatment via Telemedicine

Results - including the date you were checked and a list of what you were checked for - can be shared by users through text, e-mail or on dating profiles.

Universal Purchase Programs in the United States May Not Effectively Increase Vaccination Rates

Universal Purchase Programs in the United States May Not Effectively Increase Vaccination Rates

Using state- and individual-level data from the 1995-2014 National Immunization Survey, the effect of a state's Universal Purchase adoption on vaccination rates was estimated.

New AAP Policy on Patient Dismissal for Vaccine Refusal May "Erode Solidarity" Among Pediatricians

New AAP Policy on Patient Dismissal for Vaccine Refusal May "Erode Solidarity" Among Pediatricians

Others have argued that dismissal is ethically problematic because it can deprive children of comprehensive pediatric care and undermine public health.

Poor Adherence Contributes to Inadequate Update of Multidose Hepatitis Vaccine Schedules

Poor Adherence Contributes to Inadequate Update of Multidose Hepatitis Vaccine Schedules

Adherence and completion to multidose vaccine schedules for hepatitis A, B, and A-B are low, thereby rendering vaccination ineffective.

Vitamin D and Gestational Hypertension, Preeclampsia Risk: Is There a Connection?

Vitamin D and Gestational Hypertension, Preeclampsia Risk: Is There a Connection?

Researchers from the University of Bristol found no association between 25-hydroxyvitamin D level and pregnancy-related hypertensive disorders.

#DontFryDay: 12 Million Twitter Impressions Spread Message of Sun Safety

#DontFryDay: 12 Million Twitter Impressions Spread Message of Sun Safety

Social media is an ideal platform to reach teenagers and young adults to encourage sun safety.

Diabetes Risk Associated With Cirrhosis, Not Chronic HCV Infection, in HIV Positive Patients

Diabetes Risk Associated With Cirrhosis, Not Chronic HCV Infection, in HIV Positive Patients

Cirrhosis is associated with an increased risk for diabetes mellitus among patients living with HIV.

Chronic Pain Leads to Higher Opioid Doses and Lower QoL in Sickle Cell Patients

Chronic Pain Leads to Higher Opioid Doses and Lower QoL in Sickle Cell Patients

In adults with sickle cell disease, higher daily opioid use may be associated with poorer health-related quality of life.

Empagliflozin Reduces Risk for Nephropathy Regardless of Blood Pressure, LDL Cholesterol, HbA1c

Empagliflozin Reduces Risk for Nephropathy Regardless of Blood Pressure, LDL Cholesterol, HbA1c

Investigators examined renal outcomes when controlling cardiovascular risk factors, such as blood pressure, LDL-C, and HbA1c.

Menopausal Hormone Therapy Slows Cognitive Decline in Postmenopausal Women

Menopausal Hormone Therapy Slows Cognitive Decline in Postmenopausal Women

Hormone therapy in postmenopausal women with mild cognitive impairment was examined.

Risk for Below Knee Amputations With Canagliflozin vs Other Antihyperglycemic Agents

Risk for Below Knee Amputations With Canagliflozin vs Other Antihyperglycemic Agents

Investigators analyzed real world data to examine the risk for below-knee amputations in patients with type 2 diabetes taking canagliflozin vs other medications.

Beta-Blockers Show Varied Effects on Hypoglycemic Mortality Risk in Diabetes

Beta-Blockers Show Varied Effects on Hypoglycemic Mortality Risk in Diabetes

Investigators examined the relationship between the use of β-blockers and incidence of hypoglycemia and risk for mortality in hospitalized patients with diabetes.

Pen vs Patch Bolus Insulin Delivery for T2D Using CGM

Pen vs Patch Bolus Insulin Delivery for T2D Using CGM

Investigators compared 2 methods of delivering bolus insulin, pen vs patch, using metrics from continuous glucose monitoring.

Metabolic Health Predicative of Cognitive Development in Children

Metabolic Health Predicative of Cognitive Development in Children

Researchers assessed whether current metabolic parameters are inversely associated with cognitive functioning.

Liraglutide May Prevent Dementia in Elderly With Type 2 Diabetes

Liraglutide May Prevent Dementia in Elderly With Type 2 Diabetes

Investigators examined the efficacy of liraglutide for the prevention of dementia in elderly patients with type 2 diabetes.

Age, Baseline HbA1c May Predict Glycemic Control in Newly Diagnosed Type 2 Diabetes

Age, Baseline HbA1c May Predict Glycemic Control in Newly Diagnosed Type 2 Diabetes

Investigators examined the effectiveness of oral agents vs insulin as an initial treatment option for people newly diagnosed with type 2 diabetes.

Elevated Triglycerides, Diabetes May Be Predictors of Major Cardiovascular Events

Elevated Triglycerides, Diabetes May Be Predictors of Major Cardiovascular Events

Investigators examined cardiovascular outcomes in patients with elevated triglyceridemia and diabetes treated with statins.

Discharge Tools, Follow-Up Calls Reduce Readmission for Congestive Heart Failure

Discharge Tools, Follow-Up Calls Reduce Readmission for Congestive Heart Failure

A literature review revealed that the use of care navigators in conjunction with follow-up telephone calls from nursing staff improved transition of care and readmission rates in patients with congestive heart failure.

Preoperative Testing, Management: Addressing a Potential Hospitalist NP Gap

Preoperative Testing, Management: Addressing a Potential Hospitalist NP Gap

Hospitalist NPs are key to successfully implementing Society of Hospital Medicine guidelines for preoperative testing and management.

Assessing a Comprehensive Long-Acting Reversible Contraceptive Program

Assessing a Comprehensive Long-Acting Reversible Contraceptive Program

An evaluation assessed the nonhealthcare-related influences that have led to misconceptions about long-acting reversible contraceptives.

Nursing Faculty Ill Prepared to Educate Students on Transgender Patient Care

Nursing Faculty Ill Prepared to Educate Students on Transgender Patient Care

Nurse educators may not be fully prepared to teach students about transgender patient care.

Project ECHO: Educational Support to Improve Hepatitis Care

Project ECHO: Educational Support to Improve Hepatitis Care

Project ECHO at Los Angeles Christian Health Center contributes to improved care of HCV in underserved populations.

Ribociclib Prolongs Progression-Free Survival in Premenopausal Breast Cancer

Ribociclib Prolongs Progression-Free Survival in Premenopausal Breast Cancer

Investigators report results from the MONALEESA-7 trial, which assessed ribociclib plus endocrine therapy in premenopausal women with advanced breast cancer.

Lofexidine a Non-Narcotic Option for Opioid Withdrawal Symptoms

Lofexidine a Non-Narcotic Option for Opioid Withdrawal Symptoms

Lofexidine may help patients with opioid withdrawal symptoms or difficulty with opioid discontinuation.

Safety and Performance of Omnipod HCL for Children With Type 1 Diabetes

Safety and Performance of Omnipod HCL for Children With Type 1 Diabetes

In children with type 1 diabetes, the Omnipod hybrid closed-loop personal model system was safe and performed well.

Type 2 Diabetes Does Not Affect Pneumonia Incidence, Outcomes After Stroke

Type 2 Diabetes Does Not Affect Pneumonia Incidence, Outcomes After Stroke

Investigators examined the incidence and outcomes of pneumonia in patients with acute ischemic stroke and type 2 diabetes.

ITCA 650 Shows Efficacy in Reducing Weight, HbA1c in Type 2 Diabetes

ITCA 650 Shows Efficacy in Reducing Weight, HbA1c in Type 2 Diabetes

The ITCA 650, a small titanium osmotic mini-pump, provides a subcutaneous infusion of exenatide over 3 or 6 months.

MEDI0382 Safe, Effective for Normalizing Glucose, Weight Loss in Type 2 Diabetes

MEDI0382 Safe, Effective for Normalizing Glucose, Weight Loss in Type 2 Diabetes

MEDI0382 reduced body weight and normalized fasting and postprandial blood glucose levels in patients with type 2 diabetes.

Chronic Kidney Disease More Common in Type 2 Diabetes Than in Type 1 Diabetes

Chronic Kidney Disease More Common in Type 2 Diabetes Than in Type 1 Diabetes

Investigators examined the prevalence of chronic kidney disease in adults with type 1 diabetes compared with type 2 diabetes.

Implantable Continuous Glucose Monitoring Device Safe, Effective for Adolescents

Implantable Continuous Glucose Monitoring Device Safe, Effective for Adolescents

The safety assessment included incidence of insertion or procedure-related removal and device-related serious adverse events through 180 after insertion.

Quantification of Prevalence, Outcomes of Incidental Imaging Abnormalities

Quantification of Prevalence, Outcomes of Incidental Imaging Abnormalities

Incidental abnormalities are most frequently observed in computed tomography colonoscopy, computed tomography of the chest, and cardiac magnetic resonance imaging.

FDA Upscheduling of Hydrocodone Places Burden on APRNs

FDA Upscheduling of Hydrocodone Places Burden on APRNs

A study assessing the impact of upscheduling of hydrocodone combined medications on APRN practices in Oklahoma revealed significant barriers to effective pain management.

Buprenorphine Diversion Driven by Withdrawal Prevention, Abstinence Maintenance

Buprenorphine Diversion Driven by Withdrawal Prevention, Abstinence Maintenance

Researchers deployed a survey to individuals who had received treatment for opioid use disorder to assess their use of buprenorphine.

NKTR-181 for Chronic Lower Back Pain: SUMMIT-07 Results

NKTR-181 for Chronic Lower Back Pain: SUMMIT-07 Results

The phase 3 SUMMIT-07 trial assessed the safety, efficacy, and tolerability of a new mu-opioid receptor agonist analgesic in adults with moderate to severe chronic lower back pain.

Screening for Tardive Dyskinesia Associated with Antipsychotic Treatment

Screening for Tardive Dyskinesia Associated with Antipsychotic Treatment

Patients receiving treatment with antipsychotic agents would benefit from screening for tardive dyskinesia as these repetitive movements can negatively affect quality of life.

Oxycodone Substitute Shows Lower Abuse Potential

Oxycodone Substitute Shows Lower Abuse Potential

Investigators assessed the potential for abuse associated with NKTR-181, a new mu-opioid receptor agonist analgesic.

Transition to Naltrexone in Opioid Use Disorder Benefits from Psychosocial Assessment

Transition to Naltrexone in Opioid Use Disorder Benefits from Psychosocial Assessment

A combination of naltrexone induction and psychoeducational counseling was found to facilitate transition from active opioid use and buprenorphine maintenance in individuals with opioid use disorder.

Demographic Insights Into Hepatitis Vaccination Practices

Demographic Insights Into Hepatitis Vaccination Practices

From 2007 to 2015, the majority of initial hepatitis A, B, and A/B vaccinations were administered by primary care providers.

CDC Surveillance Information for the 2017-2018 Influenza Season in the United States

CDC Surveillance Information for the 2017-2018 Influenza Season in the United States

The 2017-2018 influenza season in the United States (October 1, 2017-May 19, 2018) was a high-severity season.

COPD End-of-Life Management Strategies: Use Could Be Expanded

COPD End-of-Life Management Strategies: Use Could Be Expanded

The use of formal palliative care services among patients with chronic obstructive pulmonary disease increased by 1% per year, going from 5.3% in 2004 to 14.3% in 2014.

Regular Repeated Assessments Align Self-Reports, Case Manager Reports in Schizophrenia

Regular Repeated Assessments Align Self-Reports, Case Manager Reports in Schizophrenia

Repeated assessments improved the patients' ability to assess their own situation and the case workers' understanding of the patients' situations.

Home Blood Pressure Monitoring Systems Quality Assessment

Home Blood Pressure Monitoring Systems Quality Assessment

An observational study was conducted in order to determine the accuracy and quality of readings provided by home blood pressure monitoring systems.

Tiotropium Once-Daily Plus ICS Maintenance May Improve Airflow Obstruction in Adult Asthma

Tiotropium Once-Daily Plus ICS Maintenance May Improve Airflow Obstruction in Adult Asthma

Researchers from the University of Rochester identified improvement in pulmonary function in symptomatic adult patients with asthma treated with once-daily tiotropium.

Budesonide ER for Ulcerative Colitis Safe Regardless of Gender, Age

Budesonide ER for Ulcerative Colitis Safe Regardless of Gender, Age

The budesonide extended-release formulation was found to be safe and well tolerated for the remission of ulcerative colitis, regardless of age or gender.

Rifaximin May Improve Abdominal Pain Symptoms in IBS-D

Rifaximin May Improve Abdominal Pain Symptoms in IBS-D

A 2-week course of treatment with rifaximin for diarrhea-predominant irritable bowel syndrome was found to improve abdominal pain symptoms.

More NPs Ordering Multitarget Stool DNA Test for Colorectal Cancer Screening

More NPs Ordering Multitarget Stool DNA Test for Colorectal Cancer Screening

The percentage of NPs who order the mt-sDNA test for colorectal cancer screening has increased significantly since the test became available in 2014.

Osteoporosis Fracture Risk Awareness Lacking in Postmenopausal Women

Osteoporosis Fracture Risk Awareness Lacking in Postmenopausal Women

Postmenopausal women have little awareness of osteoporotic fracture risk and poor understanding that a fragility fracture may be indicative of osteoporosis and that it increases future fracture risk.

Psoriasis Treatment With Biologics Often Requires Multiple Courses, Treatment Changes

Psoriasis Treatment With Biologics Often Requires Multiple Courses, Treatment Changes

The final analysis set comprised biologic-naïve individuals — individuals who had filled an initial prescription for etanercept, infliximab, adalimumab, or ustekinumab after 2 years without using any biologic agent during the study period.

First Marijuana-Based Drug Approved to Treat LGS, Dravet Syndrome

First Marijuana-Based Drug Approved to Treat LGS, Dravet Syndrome

This marks the first approved drug that contains an active ingredient derived from marijuana as well as the first treatment approved for patients with Dravet syndrome.

Post-Op Pain Treatment Gets Breakthrough Therapy Designation

Post-Op Pain Treatment Gets Breakthrough Therapy Designation

The Company indicated that they will work towards an New Drug Application submission for the treatment in the second half of 2018.

Childhood Abuse Linked to Compromised White Matter Integrity in Bipolar Disorder

Childhood Abuse Linked to Compromised White Matter Integrity in Bipolar Disorder

These findings are in line with previous research, which suggested that abuse and neglect in childhood have different effects on the brain.

CDC Issues Update for Resistant Shigella Infections

CDC Issues Update for Resistant Shigella Infections

The CDC has identified an increasing number of Shigella isolates that test within the susceptible range for the fluoroquinolone antibiotic ciprofloxacin.

Novel Antibiotic for C Difficile Infection Gets FDA's QIDP Designation

Novel Antibiotic for C Difficile Infection Gets FDA's QIDP Designation

ACX-362E is a targeted, narrow spectrum oral antibiotic that blocks the DNA replication process through inhibition of polymerase III, which has been shown to be bactericidal.

Medication Adherence Predictors in Patients With Severe Psychiatric Disorders

Medication Adherence Predictors in Patients With Severe Psychiatric Disorders

As antipsychotic medications are vital to the effective management of severe psychiatric disorders, investigators sought to examine reasons for medication nonadherence in patients with schizophrenia, bipolar disorders, and other psychotic disorders.

Diagnosis, Treatments Affected by Amyloid Results in Dementia, Nondementia Patients

Diagnosis, Treatments Affected by Amyloid Results in Dementia, Nondementia Patients

In patients with and without dementia, amyloid-positive and negative results were significantly linked to diagnoses and treatment changes.

NAPNAP, Nursing Coalition Community Oppose Border Separation of Children From Families

NAPNAP, Nursing Coalition Community Oppose Border Separation of Children From Families

NAPNAP has called on the US Department of Homeland Security, in collaboration with the Justice Department, to protect the health and wellness of immigrant children by voicing their opposition to the border separation of children and parents.

Double Lung Transplantation Improves Survival in Interstitial Pulmonary Fibrosis

Double Lung Transplantation Improves Survival in Interstitial Pulmonary Fibrosis

Double lung transplantation appears to offer superior survival outcomes to single lung transplantation in patients with interstitial pulmonary fibrosis who are younger than 70 years.

Schizophrenia, Major Depressive Disorder, Bipolar Disorder Linked With Abnormal Functional Connectivity

Schizophrenia, Major Depressive Disorder, Bipolar Disorder Linked With Abnormal Functional Connectivity

Local functional connectivity may serve as neuroimaging marker to investigate the human brain connectome.

WHO Independent High-Level Commission on Noncommunicable Diseases Issues Recommendations

WHO Independent High-Level Commission on Noncommunicable Diseases Issues Recommendations

Although heads of state and governments have pledged to reduce premature mortality from noncommunicable diseases by one-third by 2030, many countries are not on track to achieve this goal.

No Association Between Rotavirus Vaccination and Intussusception in New Study

No Association Between Rotavirus Vaccination and Intussusception in New Study

The risk of intussusception within 1 to 7 days and 8 to 21 days after rotavirus vaccination was assessed in infants age 28 to 245 days.

Normal on-Treatment ALT Linked to Reduced Hepatic Events in Hepatitis B

Normal on-Treatment ALT Linked to Reduced Hepatic Events in Hepatitis B

Patients with chronic hepatitis B have a lower risk of hepatic events if they achieve normal on-treatment ALT in the first 12 months of NA treatment.

Hearing Loss Linked to CVD Risks in Elderly

Hearing Loss Linked to CVD Risks in Elderly

Elderly patients aged 80 years and older have an increased risk of developing cardiovascular disease (CVD) with worse hearing as well as hearing deterioration.

Sex Hormone Levels May Affect Postmenopausal Heart Disease Risk

Sex Hormone Levels May Affect Postmenopausal Heart Disease Risk

Researchers assessed the effect of testosterone, estradiol, dehydroepiandrosterone, and sex hormone-binding globulin levels on coronary heart disease, heart failure, and cardiovascular disease in postmenopausal women.

Recommendations for Perioperative Pain Management in Patients With Opioid Tolerance

Recommendations for Perioperative Pain Management in Patients With Opioid Tolerance

With the increasing number of patients presenting to surgery with opioid tolerance, clinicians should be familiar with their specific analgesic needs.

Sodium Chloride Fluid Infusion Rates Do Not Affect Pediatric Diabetic Ketoacidosis

Sodium Chloride Fluid Infusion Rates Do Not Affect Pediatric Diabetic Ketoacidosis

Sodium chloride content of intravenous fluids does not affect neurologic events in children with diabetic ketoacidosis.

NSAID Use May Increase CVD Risk in Osteoarthritis

NSAID Use May Increase CVD Risk in Osteoarthritis

Nonsteroidal anti-inflammatory drug use mediated a substantial amount of cardiovascular disease risk in osteoarthritis.

Gastroesophageal Reflux in Preterm Infants: Diagnosis and Management

Gastroesophageal Reflux in Preterm Infants: Diagnosis and Management

The American Academy of Pediatrics releases a new clinical report on the diagnosis and treatment of clinically significant gastroesophageal reflux.

Rapid Decreasing Heroin Use During Opioid Substitution Treatment Associated With Treatment Success

Rapid Decreasing Heroin Use During Opioid Substitution Treatment Associated With Treatment Success

In patients receiving opioid substitution treatment for opioid use disorder (mainly involving heroin), those exhibiting a rapid decline in heroin use were found to be more likely to have successful treatment outcomes.

Genetic Risk Score Better Than APOE Alone for Assessing Risk for Alzheimer's Dementia

Genetic Risk Score Better Than APOE Alone for Assessing Risk for Alzheimer's Dementia

The genetic risk score primarily modified the risk for and onset of dementia and AD among homozygous carriers for APOE ε4.

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