Web Exclusives

Timolol effective treatment for infantile hemangiomas

Timolol effective treatment for infantile hemangiomas

Topical timolol maleate may be safe and effective for infantile hemangiomas, amid concerns about the potential overuse of propranolol.

Binge-eating disorder: a review of effective treatment options

Binge-eating disorder: a review of effective treatment options

Cognitive behavioral therapy, lisdexamfetamine, second-generation antidepressants, and topiramate reduced binge eating.

Cohort effect shows earlier and stronger effects of bipolar disorder

Cohort effect shows earlier and stronger effects of bipolar disorder

Researchers observe a cohort effect for earlier age at onset of bipolar disorder. Bipolar disorder is also more common in patients with a family history of unipolar depression and bipolar disorder.

Bipolar disorder treatment more effective in earlier stages

Bipolar disorder treatment more effective in earlier stages

Treatment initiated in the early stages of bipolar disorder is more effective than treatment in later stages.

Use of stronger antibiotics increases in US hospitals

Use of stronger antibiotics increases in US hospitals

Although the overall use of antibiotics in US hospitals is unchanged, use of broad spectrum agents has increased significantly.

The FDA approves first drug for Duchenne muscular dystrophy

The FDA approves first drug for Duchenne muscular dystrophy

Data showed an increase in dystrophin production that could predict clinical benefit among patients with DMD.

Codeine use unsafe in children, AAP issues stronger warning

Codeine use unsafe in children, AAP issues stronger warning

Additional clinical research is required to understand the risk and benefits of opioid and nonopioid alternatives for acute pain.

Multibiomarker disease activity predicts relapse in rheumatoid arthritis patients

Multibiomarker disease activity predicts relapse in rheumatoid arthritis patients

Multibiomarker disease activity improved relapse prediction in RA patients who are in remission.

Patient personality may affect treatment adherence in rheumatoid arthritis

Patient personality may affect treatment adherence in rheumatoid arthritis

Early and aggressive management of RA is urged by investigators.

Age as a determining factor in TNFi discontinuation in rheumatoid arthritis

Age as a determining factor in TNFi discontinuation in rheumatoid arthritis

It is critical to identify disease-modifying antirheumatic drugs for elderly patients with rheumatoid arthritis.

Bariatric surgery linked to an increased risk of preterm birth

Bariatric surgery linked to an increased risk of preterm birth

Pregnant women with a history of bariatric surgery may have an increased risk of preterm birth.

Menopausal transition linked to rapid increase in metabolic syndrome severity

Menopausal transition linked to rapid increase in metabolic syndrome severity

The American Heart Association found that during menopausal transition, women have a rapid increase in metabolic syndrome severity.

Acute exacerbations may accelerate lung function decline in smokers with COPD

Acute exacerbations may accelerate lung function decline in smokers with COPD

Exacerbations were associated with accelerated lung function loss in patients with established COPD.

MRI safe in early pregnancy, gadolinium use linked to adverse outcomes

MRI safe in early pregnancy, gadolinium use linked to adverse outcomes

Gadolinium-enhanced MRI is associated with an increased risk of stillbirth or neonatal death, as well as rheumatologic, inflammatory, or infiltrative skin conditions.

Screening for latent tuberculosis infection: USPSTF finalizes recommendation

Screening for latent tuberculosis infection: USPSTF finalizes recommendation

The USPSTF task force reviewed evidence regarding screening for LTBI in asymptomatic adults.

Pancreatic cancer is most lethal pancreatic disorder worldwide

Pancreatic cancer is most lethal pancreatic disorder worldwide

The mortality rate from pancreatic cancer is significantly higher in the American region than in the European and Western Pacific regions.

Hepatitis C virus core antigen testing is a highly accurate diagnostic tool

Hepatitis C virus core antigen testing is a highly accurate diagnostic tool

HCVcAg assays with signal amplification have the potential to replace NAT in settings with high HCV prevalence.

Addressing parental vaccine concerns: AAP provides guidance for clinicians

Addressing parental vaccine concerns: AAP provides guidance for clinicians

The AAP has released a report to help clinicians address the concerns of parents who are hesitant about their children's vaccination.

Obeticholic acid may be effective for primary biliary cholangitis

Obeticholic acid may be effective for primary biliary cholangitis

In patients with primary biliary cholangitis obeticholic acid was associated with significant decreases in alkaline phosphatase and total bilirubin levels.

Folic acid-fortified foods linked to lower risk of congenital heart defects

Folic acid-fortified foods linked to lower risk of congenital heart defects

Foods fortified with folic acid are associated with a decrease in infants being born with congenital heart defects.

Using neuroimaging in chronic pain management

Using neuroimaging in chronic pain management

Developments in functional, structural, and neurochemical imaging could help predict individuals with acute pain who are likely to progress to chronic pain.

Oxycodone/naloxone may be beneficial for managing pain after total knee replacement

Oxycodone/naloxone may be beneficial for managing pain after total knee replacement

Oxycodone/naloxone may provide effective analgesia and improve patients' ability to participate in physiotherapy.

Food allergies in children linked to high risk of asthma, rhinitis

Food allergies in children linked to high risk of asthma, rhinitis

Researchers measured rates of childhood allergic conditions with data from healthcare provider-based diagnoses.

Group prenatal care vs traditional prenatal care

Group prenatal care vs traditional prenatal care

Group prenatal care may lower the risk of preterm birth in African American women.

CPAP does not prevent cardiovascular events in obstructive sleep apnea

CPAP does not prevent cardiovascular events in obstructive sleep apnea

Patients with obstructive sleep apnea did not have reduced cardiovascular events after CPAP in addition to usual care.

Early intensification of diabetes therapy after metformin failure is beneficial

Early intensification of diabetes therapy after metformin failure is beneficial

Intensification of therapy within 6 months of metformin monotherapy failure resulted in rapid attainment of A1c goals.

Study cites factors behind the high cost of prescription drugs in the United States

Study cites factors behind the high cost of prescription drugs in the United States

A peer-review analysis identified the source of increasing drug prices in the United States.

Team-based care may be more effective than traditional practice management in primary care

Team-based care may be more effective than traditional practice management in primary care

Researchers compared quality of care, acute care use, and program investment costs of team-based care and traditional practices.

Many parents place their infants in unsafe sleep environments

Many parents place their infants in unsafe sleep environments

Many parents do not place their infants in a supine position, or place them on nonrecommended surfaces with loose items.

The flu shot versus flu nasal spray—which is more effective?

The flu shot versus flu nasal spray—which is more effective?

In a study of pediatric patients, vaccine coverage in both LAIV and IIV groups was similar.

Oily fish consumption may lower diabetic retinopathy risk in type 2 diabetes

Oily fish consumption may lower diabetic retinopathy risk in type 2 diabetes

A target intake of at least 500 mg/d is recommended to combat sight-threatening diabetic retinopathy.

Drug may slow renal disease progression in type 2 diabetes

Drug may slow renal disease progression in type 2 diabetes

Canagliflozin 100 mg or 300 mg slowed kidney decline compared with glimepiride.

AHA advisory: Sedentary behavior may increase cardiovascular morbidity and mortality

AHA advisory: Sedentary behavior may increase cardiovascular morbidity and mortality

The American Heart Association has released a science advisory regarding the cardiovascular risks associated with sedentary behavior.

Acetaminophen use during pregnancy linked to higher risk of childhood behavioral problems

Acetaminophen use during pregnancy linked to higher risk of childhood behavioral problems

Children exposed to acetaminophen prenatally had an increased risk of multiple behavioral difficulties.

Preventing bronchopulmonary dysplasia in preterm infants

Preventing bronchopulmonary dysplasia in preterm infants

Seven ventilation strategies were compared for efficacy in a study of 5598 preterm infants.

New guideline for managing kidney stones is released

New guideline for managing kidney stones is released

Guideline from the American Urological Association has been revised to incorporate the management of patients with staghorn renal stones.

Vital sign instability at hospital discharge linked to increased mortality risk

Vital sign instability at hospital discharge linked to increased mortality risk

Nearly 17% of patients exhibiting one unstable vital sign at hospital discharge were readmitted or died within 30 days.

Early interferon beta-1b treatment beneficial in patients with multiple sclerosis

Early interferon beta-1b treatment beneficial in patients with multiple sclerosis

Results of the BENEFIT 11 trial show that many clinical outcomes were improved with earlier interferon beta-1b treatment.

ICU care is frequently overused and may not improve hospital mortality

ICU care is frequently overused and may not improve hospital mortality

Hospital mortality rates do not improve in institutions that frequently use ICU care for patients.

FDA approves generic Tamiflu

FDA approves generic Tamiflu

Oseltamivir phosphate can be used to prevent flu in patients aged 1 year and older.

Blood pressure lower than recommended level is beneficial in type 2 diabetes

Blood pressure lower than recommended level is beneficial in type 2 diabetes

Patients with type 2 diabetes with systolic blood pressure lower than 140 mm Hg have a lower risk of cardiovascular events.

MRI may be useful in assessing hypovascular hepatic lesions

MRI may be useful in assessing hypovascular hepatic lesions

Researchers found significant differences on MRI between malignant and benign hypovascular lesions of the liver.

Chronic pancreatitis in women typically not related to alcohol use

Chronic pancreatitis in women typically not related to alcohol use

Most cases of chronic pancreatitis in women are from nonalcoholic etiologies, according to researchers.

Sedentary behavior linked to chronic pain in children

Sedentary behavior linked to chronic pain in children

Prepubertal children who regularly engage in sedentary behavior have an increased likelihood of experiencing various pain conditions.

Marijuana poisoning cases in children increase in Colorado

Marijuana poisoning cases in children increase in Colorado

Results suggest that the legalization of recreational marijuana use led to the increase in children who were unintentionally exposed to the drug.

ASCO issues guidelines for chronic pain in patients with a history of adult cancer

ASCO issues guidelines for chronic pain in patients with a history of adult cancer

Screening for pain at every visit is recommended, and management and treatment options are specified.

Lancet series highlights need for understanding and improving health care in transgender community

Lancet series highlights need for understanding and improving health care in transgender community

The Lancet aims to provide a framework to improve the health and lives of members of the transgender community across the globe.

Clinician survey indicates improved attitudes toward COPD treatment

Clinician survey indicates improved attitudes toward COPD treatment

Clinician awareness of COPD treatment guidelines has increased since 2007.

Blood eosinophil counts linked to adverse pneumonia events in COPD patients

Blood eosinophil counts linked to adverse pneumonia events in COPD patients

Patients with a blood eosinophil count below 2% had a poor response to treatment with inhaled corticosteroids.

Injectable oxymorphone, syringe sharing lead to HIV outbreak

Injectable oxymorphone, syringe sharing lead to HIV outbreak

The use of injectable, extended-release oxymorphone and syringe sharing was linked to an outbreak of HIV infections in Indiana.

FDA approves new HPV test

FDA approves new HPV test

A new HPV screening test that uses cervical cells collected for a Pap test has been approved by the FDA.

FDA approves over-the-counter Differin Gel 0.1% to treat acne

FDA approves over-the-counter Differin Gel 0.1% to treat acne

Differin Gell 0.1% (adapalene) is the first retinoid approved for over-the-counter treatment of acne by the FDA.

Does statin use benefit patients with COPD?

Does statin use benefit patients with COPD?

Potential effects of statin use as adjunct therapy in COPD patients is still widely debated.

Inpatient mortality, length of stay decreasing for COPD patients, but financial burden increasing

Inpatient mortality, length of stay decreasing for COPD patients, but financial burden increasing

For patients hospitalized with COPD, mortality and length of stay have decreased while financial burden has increased.

COPD Assessment Test can identify new COPD, mild airflow obstruction

COPD Assessment Test can identify new COPD, mild airflow obstruction

The COPD Assessment Test (CAT) can be used to distinguish between newly diagnosed patients, those with more exacerbations, and by gender.

Diabetes drugs similar regarding cardiovascular and all-cause mortality risk

Diabetes drugs similar regarding cardiovascular and all-cause mortality risk

A meta-analysis of the 9 classes of glucose-lowering drugs supports the ADA's recommendation of metformin monotherapy as preferred initial treatment.

Young patients with COPD still active smokers

Young patients with COPD still active smokers

Patients who are socioeconomically disadvantaged are more likely to continue smoking after a COPD diagnosis.

California penalties on medical errors do not reduce errors

California penalties on medical errors do not reduce errors

A program in California where hospitals are penalized for preventable medical errors has failed to reduce the number of errors.

Prenatal nicotine exposure rates higher than previously reported

Prenatal nicotine exposure rates higher than previously reported

High levels of nicotine were detected in 16.5% of study participants.

Managing aspergillosis: updated guidelines from IDSA

Managing aspergillosis: updated guidelines from IDSA

New guidelines for the treatment and management of aspergillosis have been published by the Infectious Diseases Society of America.

Common medications can cause or worsen heart failure, cautions AHA

Common medications can cause or worsen heart failure, cautions AHA

The American Heart Association has published a scientific statement that outlines which medications cause or exacerbate heart failure.

Chronic visceral pain management

Chronic visceral pain management

Pain management specialists may have an important role to play in the treatment of patients with chronic visceral pain.

State restrictions not associated with reduced opioid misuse among disabled adults

State restrictions not associated with reduced opioid misuse among disabled adults

The adoption of various state laws did not affect rates of opioid prescription or strength of dose.

Vagal nerve stimulation does not reduce mortality in heart failure patients

Vagal nerve stimulation does not reduce mortality in heart failure patients

At 16 months, 30.3% of patients either died or experienced worsening heart failure.

Acupressure effective for fatigue linked to breast cancer

Acupressure effective for fatigue linked to breast cancer

Nearly 70% of participants who self-administered acupressure therapy experienced improved levels of fatigue.

Direct-acting antivirals in hepatitis C do not reduce hepatocellular carcinoma occurrence

Direct-acting antivirals in hepatitis C do not reduce hepatocellular carcinoma occurrence

Patients previously treated for HCC have a high risk of tumor recurrence in the long term.

New York's proposed "Lavern's Law" halted in state legislature

New York's proposed "Lavern's Law" halted in state legislature

A law aimed at helping victims of medical malpractice did not pass the New York State Legislature.

Patients with atrial fibrillation and stroke risk treated with aspirin over oral anticoagulants

Patients with atrial fibrillation and stroke risk treated with aspirin over oral anticoagulants

Specific patient characteristics predicted the type of therapy more likely to be prescribed.

Exercise during pregnancy does not increase preterm birth risk

Exercise during pregnancy does not increase preterm birth risk

Women who participated in an aerobic exercise program 3 to 4 times per week during their pregnancies were not likely to give birth prematurely.

Conservative management of gallbladder disease before bariatric surgery is safe

Conservative management of gallbladder disease before bariatric surgery is safe

At 12 months, 21.2% of patients had developed de novo gallbladder disease.

Reduced inpatient hypoglycemia with electronic glycemic management system

Reduced inpatient hypoglycemia with electronic glycemic management system

The eGMS system provides patient-specific insulin dosing.

Reduced antibiotic prescribing may lead to increase in pneumonia, peritonsillar abscess cases

Reduced antibiotic prescribing may lead to increase in pneumonia, peritonsillar abscess cases

General practices that prescribe fewer antibiotics may encounter slightly higher incidences of pneumonia and peritonsillar abscess.

New questionnaire to guide treatment of patients with acromegaly

New questionnaire to guide treatment of patients with acromegaly

Patients with acromegaly often exhibit breakthrough symptoms, despite stable treatment.

Parental management of child's postoperative pain

Parental management of child's postoperative pain

Despite being well-informed, many parents struggled to manage their child's postoperative pain.

Long-acting opioid therapy linked to increased mortality risk

Long-acting opioid therapy linked to increased mortality risk

Patients with chronic, noncancer pain who were treated with long-acting opioid therapy had a 1.6 times greater risk of death.

Whole grain consumption reduces chronic disease, all-cause mortality

Whole grain consumption reduces chronic disease, all-cause mortality

Reductions in disease risk were observed for an intake as high as 7.5 servings of whole grains per day.

Coronary artery bypass linked to new-onset diabetes

Coronary artery bypass linked to new-onset diabetes

Coronary artery bypass surgery may lead to metabolic changes, causing new-onset diabetes.

New opioid use common post-hospital discharge among Medicare beneficiaries

New opioid use common post-hospital discharge among Medicare beneficiaries

After an acute hospitalization, many Medicare beneficiaries submit pharmacy claims for opioid prescriptions.

HIV viral load linked to liver fibrosis

HIV viral load linked to liver fibrosis

Patients with HIV infection and elevated viral load are likely to progress to advanced hepatic fibrosis.

Glucommander linked to improved blood glucose levels

Glucommander linked to improved blood glucose levels

Use of the Glucommander was linked to a shorter time to achieving blood glucose levels lower than 200 mg/dL.

Perinatal HIV exposure has negative psychosocial consequences

Perinatal HIV exposure has negative psychosocial consequences

Children who were perinatally exposed to HIV are more likely to struggle with psychosocial adjustment during childhood and adolescence.

Clinician calls for retraction of "flawed" BMJ study of medical errors in the U.S.

Clinician calls for retraction of "flawed" BMJ study of medical errors in the U.S.

A clinician has called for the retraction of a study that identified medical errors as the 3rd leading cause of death in the United States.

Smartphone app helps circumvent unnecessary testing for chest pain in ED patients

Smartphone app helps circumvent unnecessary testing for chest pain in ED patients

The HEART pathway app provides doctors in the ED with a digital application an already proven method of assessment.

Updated guidelines for safe sedation of pediatric patients

Updated guidelines for safe sedation of pediatric patients

Updated guidelines for safely sedating pediatric patients have been released by the AAP and AAPD.

Obesity linked to increased risk for adverse pregnancy, neonatal outcomes

Obesity linked to increased risk for adverse pregnancy, neonatal outcomes

Women categorized as class III obese were more likely to experience adverse outcomes in pregnancy and neonatal risks.

Non-vitamin K antagonist oral anticoagulants may be safe, effective

Non-vitamin K antagonist oral anticoagulants may be safe, effective

Non-vitamin K antagonist oral anticoagulants perform similarly to warfarin for patients with atrial fibrillation.

Consuming fiber from bread, cereal, fruits may improve aging process

Consuming fiber from bread, cereal, fruits may improve aging process

Consuming dietary fiber from bread, cereal, and fruit may increase the likelihood of successful aging over 10 years.

USPSTF recommends screening for colorectal cancer from age 50 to 75

USPSTF recommends screening for colorectal cancer from age 50 to 75

The USPSTF has released a recommendation statement regarding screening adults for colorectal cancer.

COPD exacerbations linked to quality of life, history of pneumonia

COPD exacerbations linked to quality of life, history of pneumonia

Patients with mild-to-moderate airflow limitations should be screened for COPD exacerbations.

Frailty affects rehabilitation outcomes in COPD patients

Frailty affects rehabilitation outcomes in COPD patients

Patients who complete pulmonary rehabilitation programs may experience short-term symptom reversal.

A step-by-step approach to managing gastrointestinal bleeding

A step-by-step approach to managing gastrointestinal bleeding

Using a stepwise approach to diagnose and treat gastrointestinal bleeding can improve patient outcomes.

Long-term breast cancer care transitioning to primary care clinicians

Long-term breast cancer care transitioning to primary care clinicians

As breast cancer survivorship increases, NPs have taken on long-term patient care.

Interventions effectively increase colon cancer screening rates

Interventions effectively increase colon cancer screening rates

Multi-level interventions can effectively increase rates of colon cancer screening in a primary care setting.

NPs provide essential health care in underserved populations

NPs provide essential health care in underserved populations

NPs provide high-quality health care to underserved and uninsured populations throughout the United States.

Gaps exist in clinician knowledge of gout management

Gaps exist in clinician knowledge of gout management

Ample opportunities exist to increase clinician's knowledge of gout identification and management.

Keep misconceptions in mind when recommending probiotics

Keep misconceptions in mind when recommending probiotics

When recommending probiotics to patients, NPs should remember that different strains have different health benefits.

Many patients lack knowledge about NSAIDs and their risks

Many patients lack knowledge about NSAIDs and their risks

Despite the widespread use of NSAIDs to treat pain, many patients lack knowledge about these medications and their risks.

AANP supports bill for full practice authority for NPs in veterans health care

AANP supports bill for full practice authority for NPs in veterans health care

The AANP held a press conference to support a bill that would grant full practice authority to all NPs within the Veterans Administration healthcare system.

Long-acting reversible contraception effective in nulliparous adolescents

Long-acting reversible contraception effective in nulliparous adolescents

LARC is safe and effective in nulliparous adolescents and should be considered as a viable alternative to oral contraception.

AANP 2016: A patient-centered mission for NPs

AANP 2016: A patient-centered mission for NPs

The American Association of Nurse Practitioners (AANP) 2016 National Conference takes place in San Antonio from June 21 through June 26.

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