Web Exclusives

Exercise won't make up for poor diet

Exercise won't make up for poor diet

The most effective intervention for reducing the features of metabolic syndrome is dietary carbohydrate restriction.

Antibiotic shortages may catch providers off guard

Antibiotic shortages may catch providers off guard

Many of the drug shortages were of broad-spectrum antibiotics.

VNN1 gene may be potential biomarker for childhood asthma

VNN1 gene may be potential biomarker for childhood asthma

The activity of a gene called vanin-1 (VNN1) affected whether they were good or poor responders to corticosteroid treatment.

Mindfulness-based cognitive therapy as effective as antidepressants

Mindfulness-based cognitive therapy as effective as antidepressants

Results of the study indicate that mindfulness-based cognitive therapy is as effective as antidepressants for preventing recurring depression .

Medical org urges FDA to ban e-cigarette flavorings, ads

Medical org urges FDA to ban e-cigarette flavorings, ads

Calling for a ban on television advertisements for e-cigarettes follows the American College's continuing policy supporting bans on all tobacco advertising.

More evidence debunks measles vaccine, autism link

More evidence debunks measles vaccine, autism link

Finding held true even for children at risk for the developmental disorder

FDA recalls Queso Fresco cheese for Staphylococcus aureus contamination

FDA recalls Queso Fresco cheese for Staphylococcus aureus contamination

To date, no illnesses are known by the Department of Agriculture and Markets to be associated with this product.

Exercise with calorie reduction benefits glucoregulation

Exercise with calorie reduction benefits glucoregulation

Weight losses were similar in all groups, but insulin sensitivity index values increased two-fold more in the calorie reduction and exercise group.

New adult congenital heart disease guidelines released

New adult congenital heart disease guidelines released

Adult patients diagnosed with congenital heart failure need to seek routine follow-up care.

Feds revisit mammography guidelines

Feds revisit mammography guidelines

Women in their 40s should make a decision whether or not to receive mammograms every two years after talking about their individual risk factors with their providers.

Long-term aspirin use may lower gastrointestinal cancer risk

Long-term aspirin use may lower gastrointestinal cancer risk

The reduced risk was largely due to fewer cases of gastrointestinal cancers, including colon cancer, rectal cancer, and esophageal cancer.

Gene variation linked to smoking duration

Gene variation linked to smoking duration

The average age of diagnosis was 61 years among those with the variation and 65 years for those without the variation.

Prepare for a bad allergy season

Prepare for a bad allergy season

Although, because pollen season started later this year, pollen season may be shorter than in past years, according to allergy experts.

Modest caffeine consumption may reduce liver scarring in patients with hepatitis C

Modest caffeine consumption may reduce liver scarring in patients with hepatitis C

About 100 milligrams of caffeine was associated with a one-third reduction of advanced liver scarring.

Subcutaneous measles vaccine superior to aerosolized vaccine

Subcutaneous measles vaccine superior to aerosolized vaccine

At day 91, 85.4% of children in the aerosol group and 94.6% in the subcutaneous group were seropositive.

Fish oil may lower atherothrombotic risk in patients with suspected coronary artery disease

Fish oil may lower atherothrombotic risk in patients with suspected coronary artery disease

Regardless of lipid-lowering therapy, patients on fish oil supplementation had lower urinary 11-dehydrothromboxane B2 levels.

Is 'flakka' the new bath salt?

Is 'flakka' the new bath salt?

Use of a new designer drug, a synthetic version of cathinone, appears to be on the rise.

Ebola vaccine trials start in West Africa

Ebola vaccine trials start in West Africa

Roughly 6,000 health workers will get shots in country hit hard by current outbreak

Gestational diabetes may up kids' autism risk

Gestational diabetes may up kids' autism risk

Under guidelines from the American College of Obstetricians and Gynecologists, women are screened for gestational diabetes, usually at 24 to 28 weeks.

Type 2 diabetes screening does not improve mortality rates

Type 2 diabetes screening does not improve mortality rates

Treatment of impaired fasting glucose, impaired glucose tolerance can delay progression to diabetes.

Quadrivalent human papillomavirus vaccine cost-effective oropharyngeal cancer prevention

Quadrivalent human papillomavirus vaccine cost-effective oropharyngeal cancer prevention

The potential costs and effectiveness of HPV4 vaccination versus no vaccination were compared in a theoretical cohort based on a cohort of 192,940 boys aged 12 years.

Assessing third-line treatment options for type 2 diabetes

Assessing third-line treatment options for type 2 diabetes

Add-on thiazolidinedione decreased HbA1c significantly better than add-on glimepiride among patients inadequately controlled on metformin + exenatide, but there were significant increases in BMI and systolic blood pressure.

Rule out pulmonary embolism by combining Wells rule and D-dimer test

Rule out pulmonary embolism by combining Wells rule and D-dimer test

Combining the Wells rule and a POC yielded a sensitivity and specificity of 94.5% and 51.0%, respectively, which when combined with a quantitative test changed to 98.6% and 47.2%, respectively.

Serious life events may increase type 1 diabetes risk in kids

Serious life events may increase type 1 diabetes risk in kids

Serious life events, such as death, illness, divorce or birth of a new child, during childhood can triple the risk for developing type 1 diabetes later.

Sam's Club savings program now offers low-cost Alzheimer, diabetes medications

Sam's Club savings program now offers low-cost Alzheimer, diabetes medications

More than 200 generic medications are available for $4 and more than 400 generic prescriptions are available for $10.

Stroke patients at higher risk for suicide

Stroke patients at higher risk for suicide

During follow-up, 1,217 suicides attempts were reported; 260 were fatal.

Are shorter people at higher risk for developing coronary artery disease?

Are shorter people at higher risk for developing coronary artery disease?

There is a relative 13.5% increase in coronary artery disease risk for every 2.5 inches shaved off a person's height.

Sleep apnea could raise psoriasis risk in women

Sleep apnea could raise psoriasis risk in women

The presence of snoring was not associated with a higher risk of psoriasis.

Depression linked to increased gestational diabetes risk

Depression linked to increased gestational diabetes risk

Significant symptoms of depression were identified in 20% of women with gestational diabetes mellitus and 13% of women without gestational diabetes mellitus.

Few weight-loss programs backed by scientific evidence

Few weight-loss programs backed by scientific evidence

Only Weight Watchers and Jenny Craig had gone through studies showing that people not only lost weight but kept it off for at least a year.

Nurse-physician collaboration cuts ICU infection rates

Nurse-physician collaboration cuts ICU infection rates

Units with more nursing hours per patient-day had a 0.42 decrease in the rate of bloodstream infections.

Researchers identify gene that causes psoriatic arthritis

Researchers identify gene that causes psoriatic arthritis

This discovery could prevent progression of psoriatic arthritis in patients with psoriasis.

Dipeptidyl peptidase-4 inhibitor use not tied to pneumonia hospitalizations

Dipeptidyl peptidase-4 inhibitor use not tied to pneumonia hospitalizations

Of the 49,653 patients included in the cohort, 562 were hospitalized for community-acquired pneumonia during follow-up.

Lifestyle interventions for diabetes yield modest weight loss results

Lifestyle interventions for diabetes yield modest weight loss results

From all 10 lifestyle intervention groups, the pooled within-group effect on weight (3,063 patients) was −5.33 kg.

Three-quarters of kids with ADHD take medication

Three-quarters of kids with ADHD take medication

Of the patients with current ADHD, 74.0% received treatment in the past week and 44.0% had received behavioral therapy in the past year.

HIV may damage central nervous system during early stages of infection

HIV may damage central nervous system during early stages of infection

Of the patients, 10% to 22% showed evidence of HIV replication or inflammation in the brain at different times within the first two years of infection.

Opioids improve breathlessness in patients with chronic obstructive pulmonary disease

Opioids improve breathlessness in patients with chronic obstructive pulmonary disease

Opioids had no impact on exercise capacity, however.

Vegetarian-vegan diets may be safe for pregnant women

Vegetarian-vegan diets may be safe for pregnant women

Vegetarian mothers were reported to have lower birth weight babies in five studies, while two studies reported higher birth weights.

Multidrug-resistant shigellosis spreads through United States

Multidrug-resistant shigellosis spreads through United States

In the United States, most Shigella is already resistant to the antibiotics ampicillin and trimethoprim/sulfamethoxazole.

Cardiovascular disease-related deaths on the rise

Cardiovascular disease-related deaths on the rise

In 1990, 12.3 million people died worldwide of heart disease. The number grew to 17.3 million by 2013, an increase of 40%.

All-oral simeprevir-sofosbuvir superior to interferon-based treatment for HCV patients with compensated cirrhosis

All-oral simeprevir-sofosbuvir superior to interferon-based treatment for HCV patients with compensated cirrhosis

Patients assigned the interferon-containing regimen had a significantly higher rate of virologic relapse compared with patients given simeprevir and sofosbuvir.

Moderate alcohol intake may cut fasting insulin

Moderate alcohol intake may cut fasting insulin

Alcohol consumption did not influence estimated insulin sensitivity or fasting glucose but was correlated with reductions in HbA1c and fasting insulin concentrations.

Methotrexate, cyclosporine among most affordable psoriasis treatments

Methotrexate, cyclosporine among most affordable psoriasis treatments

Infliximab and ustekinumab 90 mg were the most costly therapies.

Is it time to reconsider acetaminophen for back pain?

Is it time to reconsider acetaminophen for back pain?

Acetaminophen provided a small benefit in the reduction of pain and disability in patients with osteoarthritis of the hip or knee and provided no benefit in reducing pain in patients with lower back pain.

Proper screening of at-risk alcohol users is lacking

Proper screening of at-risk alcohol users is lacking

Only a minority of primary care providers appropriately screen or intervene with at-risk alcohol users.

Phase 1 trial results favorable for experimental psoriasis drug

Phase 1 trial results favorable for experimental psoriasis drug

The 31 patients who received BI 655066 had clinical improvement beginning at week 2 and maintained through week 66 weeks.

More flexible BP guidelines for coronary artery disease issued

More flexible BP guidelines for coronary artery disease issued

Guidelines reinforce a target blood pressure of less than 140/90 mm Hg for those at risk for heart attack and stroke.

Evidence lacking for prenatal iron supplementation

Evidence lacking for prenatal iron supplementation

The recommendations regarding prenatal supplements are an unchanged update from those in 2006.

Roadblocks remain in path of generic form of insulin

Roadblocks remain in path of generic form of insulin

Without insurance, insulin costs $120 to $400 per month, which can be a substantial barrier to many patients with diabetes.

Mindfulness intervention may improve fasting glucose in obese women

Mindfulness intervention may improve fasting glucose in obese women

Mindfulness-based stress reduction may benefit overweight and obese female patients.

Cardiac screening in low-risk adults

Cardiac screening in low-risk adults

Clinicians should not use resting or stress electrocardiography, stress echocardiography, or stress myocardial perfusion imaging to screen low-risk adults for cardiac disease.

Overimaging is region-based

Overimaging is region-based

Inappropriate use of imaging was strongly associated with the hospital referral regions in which patients were treated.

Lung cancer screening may be inadequate

Lung cancer screening may be inadequate

The current screening criteria for lung cancer may not be sensitive enough to protect people at risk, given the recent decline in smoking rates.

Anticoagulant use for atrial fibrillation

Anticoagulant use for atrial fibrillation

Anticoagulants are associated with an increased risk for bleeding, but for most patients, the benefits outweigh the bleeding risk.

Use metric dosing for kids' medications

Use metric dosing for kids' medications

New recommendations are designed to prevent caregivers from accidentally measuring out 10 times the prescribed dose.

H. Pylori may affect psoriasis severity

H. Pylori may affect psoriasis severity

The prevalence of H. pylori was not higher in psoriasis versus the control, but patients infected with H. pylori showed more severe psoriasis compared with uninfected patients.

MIND diet help may lower Alzheimer risk

MIND diet help may lower Alzheimer risk

The MIND diet combines the Mediterranean diet with the DASH diet, both of which call for high consumption of fruits, vegetables, and fish.

Diabetes may worsen breast cancer diagnosis

Diabetes may worsen breast cancer diagnosis

Five-year survival for breast cancer patients with diabetes was 15% lower than for those without diabetes.

Fish, PUFA intake linked to higher survival rates after breast cancer

Fish, PUFA intake linked to higher survival rates after breast cancer

All-cause mortality was reduced for those reporting the highest quartile of intake (versus never) for tuna , other baked or broiled fish , and dietary long-chain ω-3 PUFAs.

Abnormal brain responses to hunger in patients with anorexia

Abnormal brain responses to hunger in patients with anorexia

The patients who recovered from anorexia showed decreased response to reward, even when hungry.

Consuming 3 or more alcoholic drinks per day may increase liver cancer risk

Consuming 3 or more alcoholic drinks per day may increase liver cancer risk

The investigators also found that being overweight or obese boosts the chances of developing liver cancer.

Hypertension-related deaths spike in the United States

Hypertension-related deaths spike in the United States

A spike in hypertension-related death was seen in both genders and was most marked among those aged 45 to 64 years and those aged over 85 years.

FDA: Avoid amiodarone use in patients prescribed hepatitis C meds

FDA: Avoid amiodarone use in patients prescribed hepatitis C meds

Adding ledipasvir/sofosbuvir or sofosbuvir to amiodarone could cause symptomatic bradycardia, reported the FDA.

Certain antibiotics may boost type 2 diabetes risk

Certain antibiotics may boost type 2 diabetes risk

Patients who were prescribed at least two courses of four types of antibiotics -- penicillins, cephalosporins, quinolones, and macrolides -- were more likely to develop diabetes.

FDA approves expands use of diabetic retinopathy drug

FDA approves expands use of diabetic retinopathy drug

The FDA has granted expanded the use of Eylea injection to treat diabetic retinopathy in patients with diabetic macular edema (DME).

Medicaid expansion linked to increase in newly diagnosed diabetes patients

Medicaid expansion linked to increase in newly diagnosed diabetes patients

There was a 23% increase in the number of Medicaid-enrolled patients with newly identified diabetes in the 26 states and the D.C. that expanded Medicaid, compared with a 0.4% increase in the 24 states that did not expand Medicaid.

Air pollution may increase anxiety, stroke risk

Air pollution may increase anxiety, stroke risk

The findings of these two studies support a sharper focus on air pollution as a leading global health concern, according to an accompanying editorial.

Family-centered care improves ADHD symptoms

Family-centered care improves ADHD symptoms

After one year, the children as a whole showed improvements in hyperactivity, impulsivity, inattention, and social skills.

Bariatric surgery cuts asthma-related hospital visits

Bariatric surgery cuts asthma-related hospital visits

Significantly fewer ED visits or hospitalizations for asthma exacerbation occurred within 12 months after bariatric surgery.

Sleep impacts sexual desire, response in women

Sleep impacts sexual desire, response in women

Overall, women with longer average sleep duration reported better genital arousal than women with shorter average sleep length.

Multi-step intervention improves hand hygiene compliance

Multi-step intervention improves hand hygiene compliance

At both the completion of the project and three months afterward, hand hygiene compliance rates improved.

Intensive weight management, bariatric surgery yield similar results in type 2 diabetes

Intensive weight management, bariatric surgery yield similar results in type 2 diabetes

Both bariatric surgery and intensive weight management yielded similar improvements in HbA1c, weight loss and quality of life.

Nurse practitioner faces non-compete battle with former employer

Nurse practitioner faces non-compete battle with former employer

Only two states, New Jersey and Massachusetts, have ruled on patients' rights in a non-compete situation thus far.

Adiposity, weight gain up type 2 diabetes risk in patients with gestational diabetes

Adiposity, weight gain up type 2 diabetes risk in patients with gestational diabetes

Raised risk for increased baseline BMI, most recent BMI, and weight gain after gestational diabetes

Losing 30 minutes of sleep may increase obesity risk

Losing 30 minutes of sleep may increase obesity risk

For every 30 minutes of lost weekday sleep, the risk of obesity and insulin resistance increased substantially.

Assisted reproductive technology tied to higher incidence of autism

Assisted reproductive technology tied to higher incidence of autism

Correlation mainly explained by adverse prenatal and perinatal outcomes; multiple births, according to researchers.

Most psoriasis patients being treated accordingly

Most psoriasis patients being treated accordingly

Providers may have not made changes to treatment strategies due to the high effectiveness of biologics in most visits.

Diet soda linked to greater obesity in seniors

Diet soda linked to greater obesity in seniors

The mean interval in waist-circumference change in patients who drank diet soda was triple that compared with patients who did not drink diet soda.

Reduce unnecessary cardiac screening in low-risk patients

Reduce unnecessary cardiac screening in low-risk patients

Within a low-risk population, clinicians should focus on strategies for treating modifiable risk factors and encouraging healthy levels of exercise.

Obesity ups weight-related cancer risk by 40% in women

Obesity ups weight-related cancer risk by 40% in women

In a group of 1,000 obese women, 274 will be diagnosed with a body weight-linked cancer in their lifetime, compared with 194 women diagnosed in a group of 1,000 healthy weight women.

Hypogylcemia linked to deteriorated language processing

Hypogylcemia linked to deteriorated language processing

There was a significant deterioration in reading span and a decrease in correct responses with hypoglycemia.

Missouri tries to set caps on medical malpractice damages again

Missouri tries to set caps on medical malpractice damages again

Supporters of the bill believe it will reduce medical malpractice insurance rates, keep doctors from fleeing the state, and reduce incentives for frivolous lawsuits.

New hypersensitivity/allergic disease model proposed

New hypersensitivity/allergic disease model proposed

The proposed model has been presented to the World Health Organization groups in charge of International Classification of Diseases (ICD-11) revision.

Enalapril plus folic acid linked to reduced stroke risk

Enalapril plus folic acid linked to reduced stroke risk

The enalapril-folic acid group had reduced risk of first ischemic stroke and composite cardiovascular events consisting of cardiovascular death, myocardial infarction, and stroke.

PCP shortage expected by 2035

PCP shortage expected by 2035

An additional 1,700 primary-care residency slots will be necessary by 2035 based on current production.

IOM report highlights benefits of raising legal age for tobacco purchase

IOM report highlights benefits of raising legal age for tobacco purchase

Raising the legal age would save thousands of lives and lower the number of smokers, according to an Institute of Medicine report.

AMA, CDC to focus on diabetes prevention

AMA, CDC to focus on diabetes prevention

Testing Americans at risk for type 2 diabetes is the first step, experts said.

Interoperable medical devices could cut down medical errors

Interoperable medical devices could cut down medical errors

Half of the nurses surveyed reported personally witnessing a medical error due to lack of device coordination.

Poll: More Americans favor vaccination

Poll: More Americans favor vaccination

Survey results indicate that more people feel positively toward childhood vaccination in the wake of the measles outbreak.

Long-term NSAID use linked to improvements in knee osteoarthritis

Long-term NSAID use linked to improvements in knee osteoarthritis

Improvements in pain, stiffness, physical function, and in knee joint space width were found with long-term NSAID use in patients with knee osteoarthritis.

Stress, depression up heart attack, mortality risk in heart disease

Stress, depression up heart attack, mortality risk in heart disease

Coronary heart disease coupled with depression and stress significantly increases the risk for heart attack and death.

Melatonin may pose health risks for children

Melatonin may pose health risks for children

Animal research suggesting that melatonin affects reproductive and endocrine health raises questions about its safety in children with sleep disorders.

Evidence supporting herbal meds for GI disorders lacking

Evidence supporting herbal meds for GI disorders lacking

Limited evidence and a lack of quality control for manufacturing practices cast doubt on the use of herbal medicines for gastrointestinal conditions.

Reminders improve quality-assurance testing in health care

Reminders improve quality-assurance testing in health care

Postal, computer reminders equally increase adherence to quality-assurance program.

Intervention cuts inappropriate PPI prescriptions

Intervention cuts inappropriate PPI prescriptions

Increase in proportion of PPIs discontinued at hospital discharge after intervention implementation.

Parents' depression ups asthma risk for baby

Parents' depression ups asthma risk for baby

And older antidepressants in pregnancy showed similarly increased odds.

Cresemba approved for serious fungal infections

Cresemba approved for serious fungal infections

New drug targets cell walls of the fungi and is available in oral and intravenous formulations.

Treating depression helps reduce cardiovascular risk

Treating depression helps reduce cardiovascular risk

Reduced risk of death, heart disease, stroke observed in patients with moderate to severe depression who were treated with antidepressants.

Hearing loss, otologic problems more frequent with HIV

Hearing loss, otologic problems more frequent with HIV

Odds of hearing loss up for HAART-naive patients, and those receiving first- or second-line HAART