Web Exclusives

Diabetes drug lowers CVD risk in type 2 diabetes

Diabetes drug lowers CVD risk in type 2 diabetes

Fenofibrate improved lipoprotein profile more in women; CVD event reduction similar for men, women.

HPV vaccine safe for teens, provides long-term benefits

HPV vaccine safe for teens, provides long-term benefits

Vaccination-induced anti-HPV response persists through 96 months for all HPV vaccine types.

Discussing direct benefits increases parents' intent to vaccinate

Discussing direct benefits increases parents' intent to vaccinate

Emphasizing only societal benefits of MMR vaccine does not increase intention of parents to vaccinate.

Cancer drug may restore hair in alopecia patients

Cancer drug may restore hair in alopecia patients

Bone marrow cancer drug ruxolitinib appears to restore hair in patients with alopecia areata.

Chemicals found in plastics, household products reduce testosterone

Chemicals found in plastics, household products reduce testosterone

Chemicals found in many household products may reduce androgen levels in both sexes.

Stay alert for malnutrition in older patients

Stay alert for malnutrition in older patients

Sixty percent of older patients presenting to emergency department are malnourished or at risk.

CVD risks hit blacks, females harder

CVD risks hit blacks, females harder

Cutting traditional risk factors could eliminate significant amount of cardiovascular disease

High-dose flu shot better for seniors

High-dose flu shot better for seniors

A high-dose trivalent vaccine demonstrated improved protection for seniors against flu than the standard-dose vaccine.

Rapid HIV screening in ED setting accurate, feasible

Rapid HIV screening in ED setting accurate, feasible

Program serves as model for delivering public health measure in acute care setting.

Are PAs and NPs undergoing enough dermatologic training?

Are PAs and NPs undergoing enough dermatologic training?

NPs and PAs are independently performing 2.6 million dermatologic procedures in the United States.

High-dose aspirin still prescribed after myocardial infarction

High-dose aspirin still prescribed after myocardial infarction

Although data suggests low-dose aspirin offers similar results without the risk of bleeding, high-dose aspirin is still more commonly prescribed.

Does lowering sodium intake benefit or hurt CVD risk?

Does lowering sodium intake benefit or hurt CVD risk?

Three studies provide further evidence for complex link between sodium intake, cardiac health.

People with diabetes now live with disease longer

People with diabetes now live with disease longer

The number of years spent living with diabetes increased by 156% in men and by 70% in women from 1986 to 2011.

Home colorectal cancer test approved

Home colorectal cancer test approved

Cologuard, a noninvasive home-test, has been approved by the FDA to screen for colorectal cancer.

What do disease-control specialists pack to fight Ebola?

What do disease-control specialists pack to fight Ebola?

CDC disease control specialist Rebecca Merrill shares what she's packing on her trip to fight Ebola in West Africa.

Impact location does not affect concussion outcomes

Impact location does not affect concussion outcomes

Impact location in football accidents was not associated with the number of symptoms reported, prevalence of reported symptoms, or symptom resolution time.

Depression Tx risks, benefits unclear for pregnant patients

Depression Tx risks, benefits unclear for pregnant patients

Indirect evidence suggested future studies should focus on congenital anomalies, autism spectrum, and attention deficit disorders in offspring.

Multiple measurements more accurately predicts pain

Multiple measurements more accurately predicts pain

Fluctuating nature of low back pain suggests measuring outcomes more frequently may aid prediction.

Telemedicine in primary care

Telemedicine in primary care

Doctors need to invest in appropriate equipment, consider operation issues, legal issues.

CDC: Breast, cervical cancer screenings benefit millions

CDC: Breast, cervical cancer screenings benefit millions

More than 4 million female patients have been screened for breast and cervical cancer since the creation of the program.

Obstetrical complications vary fivefold across U.S. hospitals

Obstetrical complications vary fivefold across U.S. hospitals

Clinicians and policy makers should develop quality metrics to improve obstetrical outcomes.

Drug-related suicide attempts on the rise

Drug-related suicide attempts on the rise

Spikes noted among young and middle-age adults.

Low-income patients more likely to undergo diabetes-related amputation

Low-income patients more likely to undergo diabetes-related amputation

Researchers found that more non-English speaking, older male patients from low-income areas had preventable amputations.

Does losing weight make patients happier?

Does losing weight make patients happier?

Patients who reported losing more than 5% of their body weight also reported depressed moods more often.

HIV, HSV-2 coinfection linked to increase in HIV prevalence

HIV, HSV-2 coinfection linked to increase in HIV prevalence

There were marked increases in the prevalence of HIV from 7% to 13% for nearly all demographic subgroups in two cohorts of noninjection drug users.

Oritavancin is approved to treat skin infections

Oritavancin is approved to treat skin infections

The FDA has approved three drugs to treat ABSSI in 2014.

FDA is now enforcing its gluten-free standards

FDA is now enforcing its gluten-free standards

Manufacturers are now subject to scrutiny and could be subject to regulatory action if gluten-free labels are not consistent with agency standards.

Routine mammograms still benefit older female patients

Routine mammograms still benefit older female patients

Breast cancer survival was better in female patients whose cancer was detected by mammography, with 97% alive five years later.

Work-related stress increases diabetes risk

Work-related stress increases diabetes risk

Stratified analysis showed that job strain was associated with increased risk of type 2 diabetes among those with healthy and unhealthy lifestyle habits.

Abnormal B-cell function influences HIV-specific immune responses

Abnormal B-cell function influences HIV-specific immune responses

Early treatment linked with greater capacity to maintain pretreatment levels of B-cell response to virus.

Will hepatitis C become a rare disease in the next 20 years?

Will hepatitis C become a rare disease in the next 20 years?

Advancements in drug regimens and more aggressive screenings could reduce hepatitis C significantly in the next two decades.

Alcohol abuse may increase dementia risk

Alcohol abuse may increase dementia risk

The odds of severe memory impairment more than doubled with a history of alcohol use disorders.

High-dose estrogen contraception ups breast CA risk

High-dose estrogen contraception ups breast CA risk

Elevated risk observed with recent use of contraceptives involving high-dose estrogen, but not for low-dose estrogen oral contraceptives.

Eating beans, lentils, and peas aids weight loss

Eating beans, lentils, and peas aids weight loss

Patients reported feeling 31% more full after eating one serving of dietary pulses.

NPs, PAs fill gaps in rheumatology care

NPs, PAs fill gaps in rheumatology care

An increasing number of rheumatology NPs, PAs could enhance access to care.

CDC: 1 in 10 primary-care visits involves diabetes

CDC: 1 in 10 primary-care visits involves diabetes

Nearly $245 billion each year goes to the management of diabetes.

HIV undetectable in infants given early ART

HIV undetectable in infants given early ART

Starting combination antiretroviral therapy within 72 hours of birth significantly reduced HIV reservoirs.

Statin efficacy varies widely from patient to patient

Statin efficacy varies widely from patient to patient

More than 40% of those taking high-dose statins don't reach LDL-C target of <70 mg/dL

Empagliflozin approved to treat diabetes

Empagliflozin approved to treat diabetes

Pivotal trials showed that empagliflozin improved hemoglobin A1c levels compared with placebo.

High CD4 count attenuates stroke risk in HIV

High CD4 count attenuates stroke risk in HIV

Those with HIV and high CD4 cell counts had no excess risk for ischemic stroke compared with those without HIV.

Increasing activity, decreasing sitting reduces obesity risks

Increasing activity, decreasing sitting reduces obesity risks

The combined effect of high physical activity and low leisure time sitting suggests a substantially reduced risk of developing obesity.

Screen men for abdominal aneurysm

Screen men for abdominal aneurysm

The USPSTF document noted that the prevalence of AAA is 3.9% to 7.2% in men and 1.0% to 1.3% in women.

Presence, pain intensity, itch may be signs of skin cancer

Presence, pain intensity, itch may be signs of skin cancer

The prevalence of itch was 36.9%, and the prevalence of pain was 28.2% across all skin cancer, but these symptoms were mainly absent in melanomas

Travel warning issued after Ebola outbreak worsens in West Africa

Travel warning issued after Ebola outbreak worsens in West Africa

Agency also plans to send 50 more experts to the affected countries.

COPD costs projected to reach $49B in 2020

COPD costs projected to reach $49B in 2020

Nearly 13 million U.S. adults had chronic obstructive pulmonary disease in 2011, and 24 million adults had signs of impaired lung function.

Dieting young triggers greater health complications later in life

Dieting young triggers greater health complications later in life

In young women, dieting at a younger age predicts obesity, extreme weight control measures, and alcohol misuse.

IOM: GME funding system needs an overhaul

IOM: GME funding system needs an overhaul

Medicare should continue to support graduate medical education, contingent on value.

Stroke incidence, mortality declines in senior patients

Stroke incidence, mortality declines in senior patients

Incident strokes in the Medicare population aged ≥65 years decreased by approximately 40% over the last two decades.

HIV prophylaxis may also protect against herpes

HIV prophylaxis may also protect against herpes

Oral tenofovir-based prophylaxis for HIV also reduced herpes simplex virus-2 transmission.

Dietary salt intake linked to CVD in patients with T2D

Dietary salt intake linked to CVD in patients with T2D

Sodium reduction has been encouraged in guidelines for diabetes care in many countries.

New hepatitis C treatments promising

New hepatitis C treatments promising

Combined simeprevir and sofosbuvir, and an all-oral therapy with daclatasvir plus asunaprevir showed sustained virological responses.

Language barriers not associated with diabetes complications

Language barriers not associated with diabetes complications

A study of immigrant patients in Canada suggests that language barriers don't impact the risk for diabetes complications in non-native patients.

Hormonal birth control increases gestational diabetes risk

Hormonal birth control increases gestational diabetes risk

Women using barrier contraception and those using no contraception were at lower risk compared with those using hormonal contraception.

Post-cardiac-surgery stroke predictors identified

Post-cardiac-surgery stroke predictors identified

Most patients undergoing cardiac surgery have conditions such as hypertension, diabetes and atrial fibrillation.

Obesity, gestational weight gain associated with child asthma risk

Obesity, gestational weight gain associated with child asthma risk

Each 1-kg/m2 increase in maternal BMI was associated with a 2% to 3% increase in the odds of childhood asthma.

PCPs aren't recommending the HPV vaccine enough

PCPs aren't recommending the HPV vaccine enough

1/3 of parents of girls reported that their child's clinician had failed to recommended the HPV vaccination during office visits.

FDA approves extended-release painkiller

FDA approves extended-release painkiller

The medication is designed to deter abuse of the drug by snorting or injection.

Smoking during pregnancy linked to child ADHD

Smoking during pregnancy linked to child ADHD

Maternal and paternal smoking during pregnancy was associated with higher ADHD risk, but the association was stronger for females.

Probiotics may lower blood pressure

Probiotics may lower blood pressure

Effect appears to be greater when baseline blood pressure is elevated.

Antibiotics Rxs more common than antivirals for flu

Antibiotics Rxs more common than antivirals for flu

Among patients diagnosed with PCR-confirmed influenza, more receive antibiotic prescriptions than antivirals.

Clinicians' role in HIV prevention to expand

Clinicians' role in HIV prevention to expand

Combining behavioral and biomedical advancements may be the best prevention method for patients at risk of HIV.

Long-term weight loss decreases diabetes risk

Long-term weight loss decreases diabetes risk

Steady weight-loss over two years was a stronger predictor of reducing diabetes risk, compared with six months of weight-loss.

Tech program helps PCPs identify undiagnosed hypertension

Tech program helps PCPs identify undiagnosed hypertension

Hypertension is the leading modifiable risk factor for coronary artery disease, stroke, heart failure, and chronic kidney disease.

Comorbidities, social factors complicate HIV self management

Comorbidities, social factors complicate HIV self management

Low income, inflexible work schedules, and loneliness associated with difficulty self-managing comorbidities.

Experts urge reconsidering lifetime ban on blood donations from gay men

Experts urge reconsidering lifetime ban on blood donations from gay men

Citing new technologies and legal protections, the lifetime ban on blood donations from gay men should be reconsidered.

Drug-resistant CRE increasing in southeastern U.S. hospitals

Drug-resistant CRE increasing in southeastern U.S. hospitals

Greater use of broad-spectrum antibiotics, increased transmission from long-term acute care facilities associated with increases in carbapenem-resistant Enterobacteriaceae.

Medical malpractice filings drop 40% in Pennsylvania

Medical malpractice filings drop 40% in Pennsylvania

Two new state rulings are credited with the drop in malpractice filings.

Follow-up care improves heart-failure outcomes

Follow-up care improves heart-failure outcomes

Heart failure patients receiving continuity care after ED discharge were less likely to experience hospitalization or death.

CDC: Not enough teens are being tested for HIV

CDC: Not enough teens are being tested for HIV

Female and black patients were more likely to be tested for sexually transmitted diseases compared with males.

Patients may not need to fast for cholesterol tests

Patients may not need to fast for cholesterol tests

Agencies should consider re-evaluating the recommendation that patients fast before obtaining a lipid panel.

Electronic communications increase PCP visits for diabetes

Electronic communications increase PCP visits for diabetes

A 10% increase in secure message threads and telephone encounters correlated with 1.25% and 2.74% increases in office visits, respectively.

Delayed retirement has slowed predicted nursing shortage

Delayed retirement has slowed predicted nursing shortage

The economic recession and the influx of new nursing students has slowed the predicted nursing shortage in the United States.

Testicular cancer risk up in Hispanic patients

Testicular cancer risk up in Hispanic patients

A 58% increase in incidence rate per 100,000 has been noted from 1992 to 2010.

Niacin, laropiprant may not decrease vascular risk

Niacin, laropiprant may not decrease vascular risk

Adverse effects have been found in 34.2% and 32.5% of patients prescribed extended-release niacin.

Simplified approach to aspirin for heart risk prevention

Simplified approach to aspirin for heart risk prevention

Recommend aspirin for all high-risk patients without an increased risk of bleeding.

Stress, hostility increase stroke risk

Stress, hostility increase stroke risk

Correlations seen in middle-aged and older adults, even after adjustment for risk factors.

Psoriasis may be triggered by nerve cells responsible for feeling pain

Psoriasis may be triggered by nerve cells responsible for feeling pain

Researchers are investigating ways to mediate the interactions between immune cells and nerves.

Should you advise patients to eat organic?

Should you advise patients to eat organic?

A new study suggests organically grown produce and grains contain less cadmium and more antioxidants.

Behavioral weight-loss program may reduce hot flashes

Behavioral weight-loss program may reduce hot flashes

Hot flash reduction was reported as a motivator for weight loss.

Detailed screening tools help diagnose PsA

Detailed screening tools help diagnose PsA

PsA prevalence based on the patient-administered screening tools was 12% to 16% higher compared with rheumatologists' diagnosis.

Polio vaccine boosts kids' intestinal immunity

Polio vaccine boosts kids' intestinal immunity

Single dose improves intestinal immunity for children previously vaccinated with oral polio vaccine.

Routine NSAID use in females ups cardiovascular risks

Routine NSAID use in females ups cardiovascular risks

Risk up with regular NSAID use, selective cox-2 inhibitor use, agents with cox-2>cox-1 inhibition.

Update: 444,000 patients die each year due to medical errors

Update: 444,000 patients die each year due to medical errors

Medical errors are the third leading cause of death in the United States.

Drinking less alcohol benefits heart health

Drinking less alcohol benefits heart health

Patients with the rs1229984 gene variant tended to drink less and had healthier hearts.

Obesity linked to higher total mortality

Obesity linked to higher total mortality

Increasing BMI was associated with increasing number of years of life lost in class III obese patients.

Newly discovered protein may be key to psoriasis Tx

Newly discovered protein may be key to psoriasis Tx

AhR signaling in nonhematopoietic cells plays a pivotal role in prevention of excessive skin inflammation.

Kidney donation OK for select seniors

Kidney donation OK for select seniors

The combined outcome of death/cardiovascular disease was not significantly different between donors and nondonors.

WHO recognizes psoriasis as chronic condition

WHO recognizes psoriasis as chronic condition

The resolution sends a powerful global message about the serious nature of the disease.

Violence 'accepted' in the ED

Violence 'accepted' in the ED

Barriers to decreasing violence included limited recognition of high-risk patients and culture of acceptance of violence.

Poverty linked to increased PAD prevalence

Poverty linked to increased PAD prevalence

Patients who were in the lowest six poverty-income ratios were at a two-fold higher risk of peripheral artery disease.

Dupilumab effective for atopic dermatitis

Dupilumab effective for atopic dermatitis

A 50% reduction in the Eczema Area and Severity Index score (EASI-50) seen in 85% of patients in the dupilumab group.

Secukinumab effective for plaque psoriasis

Secukinumab effective for plaque psoriasis

Data from two randomized trials demonstrate efficacy of secukinumab versus placebo.

Sibling obesity better predicts child obesity

Sibling obesity better predicts child obesity

Siblings of the same gender showed stronger patterns than between siblings of different genders.

Long-term use of hypertension meds linked to psoriasis

Long-term use of hypertension meds linked to psoriasis

Psoriasis flares were seen in female patients prescribed hypertension medication.

Healthy lifestyle choices lower future CAD risk

Healthy lifestyle choices lower future CAD risk

Low alcohol intake, healthy diet, low and physical activity decreased coronary artery calcification after 20 years.

Varenicline plus nicotine replacement improves quit rates

Varenicline plus nicotine replacement improves quit rates

The combination treatment was associated with a higher continuous abstinence rate at 12 weeks and at 24 weeks.

Is a blood test that can predict Alzheimer disease on the way?

Is a blood test that can predict Alzheimer disease on the way?

Researchers have identified 10 proteins in the blood that may be predictors of Alzheimer disease.

Vaccinations safe for U.S. children

Vaccinations safe for U.S. children

Rare adverse events that may be associated with vaccination should be weighed against the protective benefits vaccines provide.

Insulin resistance increases T2D risk, independent of BMI

Insulin resistance increases T2D risk, independent of BMI

Genetic score for insulin resistance linked to lower BMI and adiposity, incident type 2 diabetes.

Malnutrition increases hypertension risk later in life

Malnutrition increases hypertension risk later in life

Patients who survived early malnutrition are reported to have weakened cardiovascular structure and function.