Six guidelines establish updated clinical practice recommendations for the evaluation, diagnosis, and treatment of obstructive sleep apnea in adults.
Anticoagulation with dabigatran was associated with fewer bleeding complications compared with warfarin among patients undergoing ablation for atrial fibrillation.
Early feeding, skin-to-skin contact improves hospital admission rates for infants at risk of hypoglycemia
A hypoglycemia bundle was created in order to reduce hospital admission rates for infants at risk of hypoglycemia.
A high BMI is associated with an increased risk for severe liver disease, and the risk is higher in those who also have type 2 diabetes mellitus.
The drug combination significantly contributes to the overall population risk of opioid overdose.
Octogenarians with colorectal cancer have several differences in clinical and tumor characteristics, compared with younger patients with the disease.
Budesonide oral suspension treatment improved symptomatic, endoscopic, and histologic parameters in eosinophilic esophagitis.
A longer period between P2Y12 inhibitor administration and primary percutaneous coronary intervention improves coronary reperfusion.
The FDA has received 120 reports of serious cases of pancreatitis or death after the approval of Viberzi in May 2015.
No difference was observed in risk of overall cancer in patients with bipolar disorder who use lithium, compared with the general population.
For many off-label indications, the prescribed drug is often not supported by strong evidence for the respective indication.
The Stepping Up model of care produced a clinically and significantly significant improvement in HbA1c among adults with type 2 diabetes managed in primary care.
Same-day discharge after percutaneous coronary intervention for non-ST-segment elevation acute coronary syndromes was not predictive of 30-day readmission, death, or bleeding.
The students improved their basic knowledge of HPV and understood the benefits of the HPV vaccine.
Using measurements of vaginal fetal fibronectin levels and cervical length did not indicate spontaneous preterm birth among first-time pregnant women.
Data presented at NAPNAP show that an early-onset sepsis calculator can decrease the number of infants who received a sepsis work-up and prophylactic antibiotics.
The ACGME announces that residency programs can increase shift hours for first-year residents from 16 to 24 hours.
A higher incidence of subdural hematomas is associated with the increased use of antithrombotic drugs, particularly vitamin k antagonists among older patients.
Implementation of the FODMAP diet is an effective strategy to manage symptoms of IBS, including bloating and abdominal pain.
Reducing postpartum depression involves universal screening and appropriate referral and treatment by clinicians.
Suboptimal intake of 10 specific dietary factors is associated with a substantial proportion of deaths due to heart disease, stroke, or type 2 diabetes.
Risk of serious infections is similar among pregnant women with systemic inflammatory conditions using steroids, non-biologics, and TNF inhibitors.
The USPSTF concludes that evidence is insufficient to assess the balance of benefits and harms of performing screening pelvic examinations in asymptomatic women for the early detection and treatment of a range of gynecologic conditions.
Point of care lung ultrasound is an accurate tool for the diagnosis of pneumonia, according to researchers.
ACOG recommends that carrier screening should be provided to all women who are pregnant but ideally should be provided to women as they are considering pregnancy.
The position statement by the ADA incorporates updates in treatment and screening for patients with diabetic retinopathy.
The American College of Gastroenterology has released recommendations of preferred approaches for diagnosing and evaluating patients with abnormal liver test results.
The guidelines outline the diagnosis of CF and clarify diagnostic criteria and terminology for other disorders associated with CFTR mutations.
Researchers report that women and men in the United States will have lower life expectancy gains, compared with those in other countries.
The American Academy of Sleep Medicine recommends that the new pharmacologic guidelines be used in conjunction with other AASM guidelines for insomnia.
Younger age, relapsing forms of MS, fewer prior immunotherapy treatments, and lower baseline EDSS score were factors associated with better outcomes for stem cell transplantation.
Patients receiving vitamin D for deficiency without bolus doses experienced the most benefit.
Among GERD patients, the mean annual ARI episode dropped from 4.39 during the year before PPI treatment to 3.89 after treatment with a PPI.
Findings from a US claims-based retrospective study call for more effective antimicrobial treatments for patients with community-acquired pneumonia.
Surgical intervention after 24.5 days of acute pancreatitis may be beneficial for reducing postoperative complications.
The Veterans Administration and Department of Defense issue a clinical practice guideline regarding opioid therapy for chronic pain in veterans.
Investigators have proposed an algorithm to facilitate the decision-making process of clinical care for patients with very early hepatocellular carcinoma.
The ACIP has released the 2017 recommended immunization schedule for adults.
MRI scans showed that the brain size of infants grew faster between 12 and 24 months, the same time that behavioral signs of autism appeared.
Rivaroxaban once daily and dabigatran twice daily showed evidence of lower thromboembolic rates.
HCV infection is associated with cancers such as bile duct and pancreatic cancers and diffuse large B-cell lymphoma.
The ACP has released 3 recommendations for the treatment of patients with acute, subacute, and chronic low back pain.
Girls whose mothers consumed high amounts of licorice during pregnancy have more advanced pubertal maturation at age 12 years.
Using transvaginal mesh and biological graft in prolapse surgery did not improve outcomes of effectiveness, quality of life, or adverse events.
The schedule includes new or revised recommendations for several vaccines for children and adolescents.
After 10 years of low-dose CT screening in patients, 1.5 lung cancers and 2.4 major cancers per 10,000 people screened were induced by radiation.
Women with a good recovery after stroke and a moderate level of optimism had a 0.40‐fold reduction in the odds of developing new-onset poststroke depression.
Atypical antipsychotic adjunctive therapy and mood stabilizers may be a more effective treatment than mood stabilizer monotherapy.
NSAID use during ARI was associated with a 3.4-fold increased risk of AMI compared with 2.7-fold increased risk without NSAID use.
Symptoms of Seoul virus infection typically begin within 1 to 2 weeks after contact with infectious material and include fever, headache, and back pain.
Researchers measured vital status records to ascertain death from 16 site-specific malignancies.
The ACOG releases an updated committee opinion suggesting that low-risk women can benefit from minimal intervention during labor and delivery.
The Seeker System is approved to screen for four rare lysosomal storage disorders in newborns.
More than 10,000 Medicare beneficiaries die each year within 7 days of being discharged from emergency departments.
Researchers observed a somewhat lower mortality among patients treated by international graduates.
Electronic cigarettes cause an imbalance of cardiac autonomic tone and increased oxidative stress, which may increase cardiovascular risk.
Higher-potency statins increased hospitalization for community-acquired pneumonia compared with lower-potency statins.
Endobronchial suture should be considered in patients with recurrent pneumonia that is unresponsive to medical therapy.
Polyvalent pneumococcal vaccines offered protection against community-acquired pneumonia in COPD patients.
The AHA found that irregular eating patterns are less ideal for maintaining body weight and cardiometabolic health.
The PPSV23 vaccine may not prevent pneumonia in patients with rheumatoid arthritis.
An estimated 900,000 veterans of a population of 6.7 million VHA patients met the criteria for LCS.
Diabetes without insulin did not appear to increase thromboembolic risk in patients with atrial fibrillation treated with anticoagulation.
Treatment is associated with decreased loss of pregnancy among women with subclinical hypothyroidism.
Prediabetes does not always show clear symptoms; however, it can lead to type 2 diabetes, heart disease, or stroke.
Updated international guidelines for managing sepsis and septic shock have been released by the Society of Critical Care Medicine and European Society of Intensive Care Medicine.
Overall, US youth consumed an average 143 kcal from sugar-sweetened beverages, with boys consuming a higher percentage of calories than girls.
Fasting glucose is specific but not sensitive, and HbA1c is neither sensitive nor specific.
The guideline aims to help clinicians identify patients with cerumen impaction who may benefit from intervention.
The USPSTF found that there is uncertainty about the accuracy of screening tools for obstructive sleep apnea in adults.
RASIs reduced cardiovascular events and death only when compared with placebo but not when compared with active controls.
About one-third of adults with physician-diagnosed asthma in the last 5 years may not have a current diagnosis.
Trulance has been approved for the treatment of chronic idiopathic constipation in adults.
The device has shut down due to an intermittent connection between the battery and electrical contacts.
For adults, the recommended serving size of fish is 4 ounces, while servings for children should be smaller based on their age and calorie intake.
Data from the PROWL studies show that most patients are satisfied with LASIK surgery, although many patients experience new symptoms.
The ACP and the AAFP has released a joint recommendation for the pharmacologic treatment of hypertension in adults aged 60 years and older.
Surgical patients with a history of migraine have an increased risk of perioperative ischemic stroke and a higher 30-day hospital readmission rate.
The declining rates for lithium use are linked to the burden of side effects and toxicity associated with the drug.
Individuals who perform their physical activity in 1 or 2 sessions during the week can still reduce their risk of mortality.
Some aspects of depression literacy were lower among patients with depression.
Recent advances in measuring asthma control tools have enhanced ongoing assessment and monitoring of asthma.
Substance use is associated with an increased risk of adolescent firearm homicide.
The USPSTF recommends folic acid supplement for all women who are capable of pregnancy or who are planning to become pregnant.
Spending on diabetes, IHD, and lower back and neck pain account for the highest amounts of spending by disease category.
The NIAID has issued addendum guidelines regarding the early introduction of peanut-containing foods to infants at risk for peanut allergies.
Budesonide/formoterol treatment decreased exacerbations in COPD after 3 months.
Self-estimated life expectancy rates may differ from clinician-estimated rates of survival.
Prescription rates for statins were dependent on age among patients with severe dyslipidemia.
Many patients with COPD report morning symptoms that are negatively associated with physical activity.
The study suggests that neither fish oil nor aspirin can be recommended for the prevention of AVF failure.
Patients diagnosed with a prior psychiatric condition have increased odds of long-term opioid receipt than patients without these conditions.
The ACP has updated the 2012 guideline to provide clinical recommendations of oral pharmacologic treatment of type 2 diabetes.
The FDA has approved a continuous glucose monitoring system to replace fingerstick blood sugar testing in patients with diabetes.
The guidelines provide a clinical framework for the diagnosis and treatment of male urethral stricture.
The HIV-positive population of the United Kingdom has a higher risk of death than the general population, despite availability of free treatment and care.
This finding suggests that any fetus with a suspected brain abnormality on ultrasound should have iuMRI to better inform counseling and management decisions.
The potency of synthetic cannabinoids is consistent with strong depressant effects that account for "zombie-like" behavior.
The FDA has issued a final ruling to ban powdered surgeon's gloves, powdered patient examination gloves, and absorbable powder for lubricating a surgeon's glove.
The USPSTF has released a final recommendation against routine serologic screening for genital herpes simplex virus infection.
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Clinical Advisor Articles
- Off-label antidepressant prescriptions not supported by strong scientific evidence
- Opioid and benzodiazepine combination use significantly increases overdose risk
- Budesonide oral suspension may be effective for eosinophilic esophagitis
- Irritable bowel syndrome medication linked to pancreatitis in certain patients
- Insulin initiation in primary care improves HbA1c levels
- Physical activity important for adults with CVD
- Annual rate of perinatal HIV infection decreased in United States
- ICU may be overused for some patients with heart or lung disease
- Obstructive sleep apnea in adults: a new clinical practice guideline
- Dabigatran linked to fewer bleeding complications in patients with atrial fibrillation